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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AYARTLDRAVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDRVDRDRMEKIRRYLLHEQREDGTWALYPGGPPDLD
TTIEAYVALKYIGMSRDEEPMQKALRFIQSQGGIESSRVFTRMWLALVGEYPWEKVPMVPPEIMFLGKRMPLNIYEFGSW
ARATVVALSIVMSRQPVFPLPERARVPELYETDVPPRRRGAKGGGGWIFDALDRALHGYQKLSVHPFRRAAEIRALDWLL
ERQAGDGSWGGIQPPWFYALIALKILDMTQHPAFIKGWEGLELYGVELDYGGWMFQASISPVWDTGLAVLALRAAGLPAD
HDRLVKAGEWLLDRQITVPGDWAVKRPNLKPGGFAFQFDNVYYPDVDDTAVVVWALNTLRLPDERRRRDAMTKGFRWIVG
MQSSNGGWGAYDVDNTSDLPNHIPFCDFGEVTDPPSEDVTAHVLECFGSFGYDDAWKVIRRAVEYLKREQKPDGSWFGRW
GVNYLYGTGAVVSALKAVGIDTREPYIQKALDWVEQHQNPDGGWGEDCRSYEDPAYAGKGASTPSQTAWALMALIAGGRA
ESEAARRGVQYLVETQRPDGGWDEPYYTGTGFPGDFYLGYTMYRHVFPTLALGRYKQAI

The query sequence (length=619) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2sqc:A 623 619 0.9968 0.9904 0.9968 0.0 1gsz:A, 1gsz:B, 1gsz:C, 1h35:A, 1h35:B, 1h35:C, 1h36:A, 1h36:B, 1h36:C, 1h37:A, 1h37:B, 1h37:C, 1h39:A, 1h39:B, 1h39:C, 1h3a:A, 1h3a:B, 1h3a:C, 1h3b:A, 1h3b:B, 1h3b:C, 1h3c:A, 1h3c:B, 1h3c:C, 1o6h:A, 1o6h:B, 1o6h:C, 1o6q:A, 1o6q:B, 1o6q:C, 1o6r:A, 1o6r:B, 1o6r:C, 1o79:A, 1o79:B, 1o79:C, 2sqc:B, 1ump:A, 1ump:B, 1ump:C
2 1w6j:A 727 651 0.2698 0.2297 0.2565 2.60e-43 1w6k:A
3 7xqz:A 493 237 0.1050 0.1318 0.2743 5.21e-09 7xr7:A, 7xra:A, 7xru:A
4 7xqz:A 493 124 0.0501 0.0629 0.2500 4.3 7xr7:A, 7xra:A, 7xru:A
5 6sbc:A 352 137 0.0630 0.1108 0.2847 0.015 6sbd:A, 6sbe:A, 6sbg:A
6 7awm:A 412 68 0.0372 0.0558 0.3382 0.34 7awl:A, 7awn:A, 7awp:A, 7awq:A, 5llm:A, 5llu:A, 5lm4:A, 5mju:A
7 8qrr:B 420 29 0.0226 0.0333 0.4828 0.45 8oud:A, 8oud:B, 8oud:C, 8qro:A, 8qro:B, 8qro:C, 8qrp:B, 8qrq:B, 8qrs:B, 8qru:B
8 6mpb:B 446 29 0.0226 0.0314 0.4828 0.49 7bcq:A, 7bcq:B, 7bcq:C, 7bcs:A, 7bcs:B, 7bcs:C, 6gct:A, 6gct:B, 6gct:C, 6mpb:C, 6mpb:A, 8ouh:A, 8ouh:B, 8ouj:A, 8ouj:B
9 1dce:B 329 79 0.0420 0.0790 0.3291 0.94 3c72:B, 1dce:D, 3dss:B, 3dst:B, 3dsu:B, 3dsv:B, 3dsw:B, 3dsx:B, 4ehm:B, 4gts:B, 4gtt:B, 4gtv:B, 3hxb:B, 3hxc:B, 3hxd:B, 3hxe:B, 3hxf:B, 6j6x:B, 6j74:B, 6j7f:B, 6j7x:B, 1ltx:B, 6o60:B, 3pz1:B, 3pz2:B, 3pz3:B
10 5g5g:B 316 83 0.0388 0.0759 0.2892 1.2 5g5h:B
11 3awj:A 380 82 0.0420 0.0684 0.3171 1.4
12 8fac:A 1377 114 0.0485 0.0218 0.2632 1.7 8e04:A
13 7xr4:A 425 74 0.0404 0.0588 0.3378 2.2 7vr7:A, 7vr8:A, 7xr4:B, 7xr4:C, 7xr6:A, 7xr6:B, 7xr6:C
14 7y47:B 767 27 0.0194 0.0156 0.4444 2.4
15 8ih5:A 689 22 0.0162 0.0145 0.4545 6.2 8ih5:F, 8ih5:B, 8ih5:C, 8ih5:D, 8ih5:E
16 1ft1:B 416 161 0.0582 0.0865 0.2236 6.4 2bed:B, 1d8d:B, 1d8e:B, 3dpy:B, 3e30:B, 3e32:B, 3e33:B, 3e34:B, 3e37:B, 8e9e:B, 3eu5:B, 3euv:B, 2f0y:B, 1fpp:B, 1ft2:B, 4gtm:B, 4gto:B, 4gtp:B, 4gtq:B, 4gtr:B, 2h6f:B, 2h6g:B, 2h6h:B, 2h6i:B, 2iej:B, 1jcq:B, 1jcr:B, 1jcs:B, 3ksl:B, 3ksq:B, 1kzo:B, 1kzp:B, 1ld7:B, 1ld8:B, 1mzc:B, 1n94:B, 1n95:B, 1n9a:B, 1ni1:B, 1nl4:B, 1o1r:B, 1o1s:B, 1o1t:B, 1o5m:B, 3pz4:B, 1qbq:B, 2r2l:B, 7rn5:B, 7rni:B, 1s63:B, 1sa4:B, 1sa5:B, 1tn6:B, 1tn7:B, 1tn8:B, 1x81:B, 2zir:B, 2zis:B
17 6nkf:A 301 73 0.0307 0.0631 0.2603 6.5 6nkf:D
18 6rfl:Y 600 37 0.0178 0.0183 0.2973 6.6 7aoh:Y, 8c8h:Y
19 8e05:A 1749 28 0.0210 0.0074 0.4643 7.9 8e05:B, 8e06:A
20 3ho8:D 934 44 0.0226 0.0150 0.3182 8.9
21 3bg5:A 1137 44 0.0226 0.0123 0.3182 8.9 3bg5:C, 8gk8:A, 8gk8:B, 3hb9:A, 3hb9:C, 3hbl:A, 3hbl:C, 4hnt:A, 4hnt:C, 4hnu:A, 4hnu:C, 4hnv:A, 4hnv:C
22 7nyw:J 135 38 0.0210 0.0963 0.3421 9.9 7nyw:I, 7nyx:I, 7nyx:J, 7nyz:I, 7nyz:J, 7nz0:I, 7nz0:J, 7nz2:I1, 7nz2:J1, 7nz2:I2, 7nz2:J2, 7nz2:I3, 7nz2:J3, 7nz2:I4, 7nz2:J4, 7nz3:I2, 7nz3:J2, 7nz3:I1, 7nz3:J1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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