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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AVPKRKMSRSNTRHRRSQWKTVATKLVTCANPACGEKHLPHTACPSCGGYGPRGDRRQVVEA

The query sequence (length=62) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 9c4g:z 62 62 1.0000 1.0000 1.0000 9.46e-42 8crx:z, 8cvm:z
2 5xym:0 55 30 0.3226 0.3636 0.6667 2.05e-07 6dzi:b, 6dzp:b, 8fr8:8, 8kab:b, 5o60:b, 5o61:b, 7s0s:c, 8v9j:4, 8v9k:4, 8v9l:4, 8whx:5, 8why:5, 8wi7:5, 8wi8:5, 8wib:5, 8wic:5, 7xam:b, 8xz3:b, 7y41:b, 5zeb:3, 5zep:z, 5zet:3
3 7a0r:Z 58 59 0.4194 0.4483 0.4407 1.53e-06 7a0s:Z, 7a18:Z, 3cf5:Y, 3dll:Y, 5dm6:Z, 5dm7:Z, 4io9:Z, 4ioa:Z, 4ioc:Z, 1j5a:M, 5jvg:Z, 5jvh:Z, 1jzx:M, 1jzy:M, 1jzz:M, 1k01:M, 1nkw:Z, 1nwx:Z, 1nwy:Z, 1ond:Z, 3pio:Z, 3pip:Z, 1sm1:Z, 4u67:Z, 4v49:BZ, 4v4a:BZ, 4v4g:B2, 4v4g:D2, 4v4g:F2, 4v4g:H2, 4v4g:J2, 4v4p:A5, 4v4r:B5, 4v4s:B5, 4v4t:B5, 4wfn:Z, 1xbp:Z, 2zjp:Y, 2zjq:Z, 2zjr:Z
4 3j3v:0 55 50 0.3226 0.3636 0.4000 1.87e-06 7aqc:b, 7aqd:b, 7as8:f, 7as9:f, 8buu:0, 6ha1:0, 6ha8:0, 6htq:1, 3j3w:0, 3j9w:B4, 5njt:p, 7o5b:0, 7ope:f, 6ppf:b, 6ppk:b, 6pvk:b, 8qcq:0, 7qgu:b, 7qh4:b, 8qpp:0, 7qv1:0, 7qv2:0, 7qv3:0, 8r55:0, 8s1p:0, 8s1u:0, 7s9u:b, 7sae:b, 6tnn:p, 6tpq:p
5 8a57:5 53 50 0.3387 0.3962 0.4200 1.98e-06 8a5i:5, 8a63:5, 7nhn:5, 8uu4:4, 8uu5:4, 8uu6:4, 8uu7:4, 8uu8:4, 8uu9:4, 8uua:4
6 6o8w:2 56 50 0.3226 0.3571 0.4000 4.78e-06 7nhk:4, 6o8x:2, 6o8y:2, 6o8z:2, 6o90:2, 7p7q:4, 7p7r:4, 7p7s:4, 7p7t:4, 7p7u:4, 6w6p:2, 6wu9:2
7 7lh5:D5 60 50 0.3387 0.3500 0.4200 2.12e-05 5a9z:Ab, 5aa0:Ab, 7azo:L32A, 7azo:L32B, 7azs:L32A, 7azs:L32B, 9b00:15, 9b00:25, 6b4v:CA, 6b4v:GC, 6boh:CA, 6boh:HC, 6bok:CA, 6bok:FC, 6buw:R5, 6buw:Y5, 6bz6:R5, 6bz6:Y5, 6bz7:R5, 6bz7:Y5, 6bz8:R5, 6bz8:Y5, 6c5l:B5, 6c5l:D5, 6cae:15, 6cae:25, 6cfj:15, 6cfj:25, 6cfk:15, 6cfk:25, 6cfl:15, 6cfl:25, 8cvj:15, 8cvj:25, 8cvk:15, 8cvk:25, 8cvl:15, 8cvl:25, 5czp:Y5, 5czp:R5, 6czr:15, 6czr:25, 5d8b:Y, 5d8b:UB, 5dfe:Y5, 5dfe:R5, 5dox:15, 5dox:25, 5doy:15, 5doy:25, 5e7k:N8, 5e7k:J5, 5e81:N8, 5e81:J5, 8ekb:15, 8ekb:25, 5el4:N8, 5el4:J5, 5el5:N8, 5el5:J5, 5el6:N8, 5el6:J5, 5el7:N8, 5el7:J5, 8ev6:15, 8ev6:25, 8ev7:15, 8ev7:25, 5f8k:15, 5f8k:25, 8fc1:15, 8fc1:25, 8fc2:15, 8fc2:25, 8fc3:15, 8fc3:25, 8fc4:15, 8fc4:25, 8fc5:15, 8fc5:25, 8fc6:15, 8fc6:25, 5fdu:15, 5fdu:25, 5fdv:15, 5fdv:25, 6fkr:15, 6fkr:25, 8fom:R5, 8fom:Y5, 8fon:R5, 8fon:Y5, 8g29:15, 8g29:25, 8g2a:15, 8g2a:25, 8g2b:15, 8g2b:25, 8g2c:15, 8g2c:25, 8g2d:15, 8g2d:25, 6gsj:N8, 6gsj:J5, 6gsk:N8, 6gsk:J5, 6gsl:N8, 6gsl:J5, 6gzq:a1, 6gzx:a1, 6gzx:a2, 6gzz:a1, 6gzz:a2, 5hau:13, 5hau:23, 5hcp:15, 5hcp:25, 5hcq:15, 5hcq:25, 5hcr:15, 5hcr:25, 5hd1:15, 5hd1:25, 5ib7:N8, 5ib7:J5, 5ib8:N8, 5ib8:J5, 5ibb:N8, 5ibb:J5, 5imq:w, 5imr:w, 5j30:R5, 5j30:Y5, 5j3c:R5, 5j3c:Y5, 5j4b:15, 5j4b:25, 5j4c:15, 5j4c:25, 5j4d:CA, 5j4d:HC, 5j8b:5, 7jql:15, 7jql:25, 7jqm:15, 7jqm:25, 4l47:R5, 4l47:Y5, 4l71:R5, 4l71:Y5, 4lel:R5, 4lel:Y5, 4lfz:R5, 4lfz:Y5, 7lh5:B5, 4lnt:R5, 4lnt:Y5, 4lsk:R5, 4lsk:Y5, 4lt8:R5, 4lt8:Y5, 7md7:15, 7md7:25, 6n1d:AL32, 6n1d:BL32, 6n9e:15, 6n9e:25, 6n9f:15, 6n9f:25, 5ndj:N8, 5ndj:J5, 5ndk:N8, 5ndk:J5, 6nd5:15, 6nd5:25, 6nd6:15, 6nd6:25, 6ndk:R5, 6ndk:Y5, 6nsh:R5, 6nsh:Y5, 6nta:R5, 6nta:Y5, 6nuo:R5, 6nuo:Y5, 6nwy:R5, 6nwy:Y5, 6o3m:R5, 6o3m:Y5, 6o97:15, 6o97:25, 6of1:15, 6of1:25, 6of6:R5, 6of6:Y5, 6oj2:R5, 6oj2:Y5, 6ope:R5, 6ope:Y5, 6ord:R5, 6ord:Y5, 6osi:R5, 6osi:Y5, 5ot7:a, 6otr:R5, 6otr:Y5, 6oxa:R5, 6oxa:Y5, 6oxi:R5, 6oxi:Y5, 4p6f:R5, 4p6f:Y5, 4p70:R5, 4p70:Y5, 6q95:b, 6qnq:N8, 6qnq:J5, 6qnr:N8, 6qnr:J5, 7rq8:15, 7rq8:25, 7rq9:15, 7rq9:25, 7rqa:15, 7rqa:25, 7rqb:15, 7rqb:25, 7rqc:15, 7rqc:25, 7rqd:15, 7rqd:25, 7rqe:15, 7rqe:25, 8t8b:15, 8t8b:25, 8t8c:15, 8t8c:25, 4tua:R5, 4tua:Y5, 4tub:R5, 4tub:Y5, 4tuc:R5, 4tuc:Y5, 4tud:R5, 4tud:Y5, 4tue:R5, 4tue:Y5, 7u2h:15, 7u2h:25, 7u2i:15, 7u2i:25, 7u2j:15, 7u2j:25, 6ucq:15, 6ucq:25, 8ud6:15, 8ud6:25, 8ud7:15, 8ud7:25, 8ud8:15, 8ud8:25, 6uo1:15, 6uo1:25, 5uq7:5, 5uq8:5, 8uvr:15, 8uvr:25, 8uvs:15, 8uvs:25, 4v4i:Y, 4v4j:Y, 4v4x:B4, 4v4y:B4, 4v4z:B4, 4v51:B5, 4v51:D5, 4v5a:B5, 4v5a:D5, 4v5c:B5, 4v5c:D5, 4v5d:B5, 4v5d:D5, 4v5e:B5, 4v5e:D5, 4v5f:B5, 4v5f:D5, 4v5g:B5, 4v5g:D5, 4v5j:B5, 4v5j:D5, 4v5k:B5, 4v5k:D5, 4v5l:B5, 4v5m:B5, 4v5n:B5, 4v5p:B5, 4v5p:D5, 4v5q:B5, 4v5q:D5, 4v5r:B5, 4v5r:D5, 4v5s:B5, 4v5s:D5, 4v63:B5, 4v63:D5, 4v67:B5, 4v67:D5, 4v68:B5, 4v6a:B5, 4v6a:D5, 4v6f:A5, 4v6f:D5, 4v6g:B5, 4v6g:D5, 4v7j:A5, 4v7j:B5, 4v7k:A5, 4v7k:B5, 4v7l:B5, 4v7l:D5, 4v7m:B5, 4v7m:D5, 4v7p:B2, 4v7p:C2, 4v7w:B5, 4v7w:D5, 4v7x:B5, 4v7x:D5, 4v7y:B5, 4v7y:D5, 4v7z:B5, 4v7z:D5, 4v83:B2, 4v83:D2, 4v84:B2, 4v84:D2, 4v87:A5, 4v87:D5, 4v8a:A5, 4v8a:B5, 4v8b:B5, 4v8b:D5, 4v8c:A5, 4v8c:B5, 4v8d:B5, 4v8d:D5, 4v8e:A5, 4v8e:C5, 4v8f:A5, 4v8f:D5, 4v8g:B5, 4v8g:D5, 4v8h:B5, 4v8h:D5, 4v8i:B5, 4v8i:D5, 4v8j:B5, 4v8j:D5, 4v8n:B5, 4v8n:D5, 4v8o:B5, 4v8q:A5, 4v8u:B5, 4v8u:D5, 4v8x:B5, 4v8x:D5, 5v8i:15, 5v8i:25, 4v90:B5, 4v95:B5, 4v95:D5, 4v97:B5, 4v97:D5, 4v9a:B5, 4v9a:D5, 4v9b:B5, 4v9b:D5, 4v9h:B5, 4v9i:B5, 4v9i:D5, 4v9j:B5, 4v9j:D5, 4v9k:B5, 4v9k:D5, 4v9l:B5, 4v9l:D5, 4v9m:B5, 4v9m:D5, 4v9n:B5, 4v9n:D5, 4v9q:A2, 4v9q:C2, 4v9r:B5, 4v9r:D5, 4v9s:B5, 4v9s:D5, 5vp2:15, 5vp2:25, 5vpo:R5, 5vpo:Y5, 5vpp:R5, 5vpp:Y5, 8vtu:15, 8vtu:25, 8vtv:15, 8vtv:25, 8vtw:15, 8vtw:25, 8vtx:15, 8vtx:25, 8vty:15, 8vty:25, 1vvj:R5, 1vvj:Y5, 1vy4:B5, 1vy4:D5, 1vy5:B5, 1vy5:D5, 1vy6:B5, 1vy6:D5, 1vy7:B5, 1vy7:D5, 4w29:B5, 4w29:D5, 4w2e:5, 4w2f:B5, 4w2f:D5, 4w2g:B5, 4w2g:D5, 4w2h:B5, 4w2h:D5, 4w2i:B5, 4w2i:D5, 4w4g:R5, 4w4g:Y5, 5w4k:15, 5w4k:25, 5wis:15, 5wis:25, 5wit:15, 5wit:25, 4wpo:A5, 4wpo:C5, 4wq1:N8, 4wq1:J5, 4wqf:A5, 4wqf:C5, 4wqr:N8, 4wqr:J5, 4wqu:A5, 4wqu:C5, 4wqy:A5, 4wqy:C5, 4wr6:N8, 4wr6:J5, 4wra:N8, 4wra:J5, 4wro:N8, 4wsd:N8, 4wsd:J5, 4wsm:N8, 4wsm:J5, 4wt1:N8, 4wt1:J5, 4wt8:C6, 4wt8:D6, 4wu1:N8, 4wu1:J5, 4wzd:N8, 4wzd:J5, 4wzo:N8, 4wzo:J5, 4xej:AL32, 4xej:BL32, 6xhv:15, 6xhv:25, 6xhw:15, 6xhw:25, 6xhx:15, 6xhx:25, 6xhy:15, 6xhy:25, 6xqd:15, 6xqd:25, 6xqe:15, 6xqe:25, 4y4o:15, 4y4o:25, 4y4p:15, 4y4p:25, 4ypb:R5, 4ypb:Y5, 4yzv:R5, 4yzv:Y5, 4z3s:15, 4z3s:25, 4z8c:15, 4z8c:25, 4zer:15, 4zer:25, 5zlu:x, 4zsn:R5, 4zsn:Y5
8 5li0:4 56 51 0.3226 0.3571 0.3922 6.93e-05 7asm:Z, 7asn:b, 7aso:g, 7asp:Z, 6ddd:N, 6ddg:N, 6fxc:AZ, 6fxc:BZ, 5hkv:Z, 5hl7:Z, 6hma:Z, 5nd8:4, 5nd9:4, 5ngm:AZ, 7nhl:5, 7nhm:5, 5nrg:Z, 8p2f:5, 8p2g:5, 8p2h:5, 7p48:Z, 6s0x:Z, 6s0z:Z, 6s12:Z, 6s13:Z, 5t7v:LE, 5tcu:LE, 7ttu:N, 7ttw:N, 4wce:Z, 4wf9:Z, 4wfa:Z, 4wfb:Z, 6wqn:N, 6wqq:N, 6wrs:N, 6wru:N, 8y36:Z, 8y37:Z, 8y38:Z, 8y39:Z, 6yef:4
9 7jil:b 59 60 0.3871 0.4068 0.4000 2.87e-04
10 6ywe:W 59 51 0.3710 0.3898 0.4510 0.006 6yws:W, 6ywv:W, 6ywx:W, 6ywy:W
11 8a22:Az 59 55 0.3226 0.3390 0.3636 4.3 8apn:Az, 8apo:Az
12 5a07:A 395 13 0.1129 0.0177 0.5385 5.7 5a07:B, 5a08:B
13 5oar:D 498 31 0.1935 0.0241 0.3871 6.0 5oar:B
14 5zb8:A 400 18 0.1290 0.0200 0.4444 6.5 7k30:A, 7k31:A, 7k32:A, 7k33:A, 5zb8:B, 5zb8:C, 5zb8:D, 5zb8:E
15 3zqj:D 921 14 0.1290 0.0087 0.5714 7.4 3zqj:B, 3zqj:E
16 2o03:A 129 22 0.1613 0.0775 0.4545 7.5
17 5aaz:A 31 23 0.1290 0.2581 0.3478 7.5
18 3zqj:C 890 14 0.1290 0.0090 0.5714 8.0
19 2r6f:A 899 15 0.1129 0.0078 0.4667 8.0
20 3zqj:A 944 14 0.1290 0.0085 0.5714 8.0
21 3uwx:A 945 15 0.1129 0.0074 0.4667 8.5
22 8ouw:2 701 11 0.1290 0.0114 0.7273 8.8
23 2r6f:B 879 15 0.1129 0.0080 0.4667 8.9
24 6knb:B 1120 26 0.1452 0.0080 0.3462 9.9 6knc:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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