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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AVKGGSFLVDEITIDQVFTPEDFSSEHKMIAKTTEDFIVNEVLPELEYLEQHEFDRSVRLLKEAGELGLLGADVPEEYGG
IGLDKVSSALIAEKFSRAGGFAITHGAHVGIGSLPIVLFGNEEQKKKYLPLLATGEKLAAYALTEPGSGSDALGAKTTAR
LNAEGTHYVLNGEKQWITNSAFADVFIVYAKIDGEHFSAFIVEKDYAGVSTSPEEKKMGIKCSSTRTLILEDALVPKENL
LGEIGKGHIIAFNILNIGRYKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAAKTYAAESSVYRTVG
LFESRMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDEGVQIHGGYGFMAEYEIERMYRDSRINRIFEGT
NEINRLIVPGTFLRKAMKGELPLLQKAQKLQEELMMMMPEEVGDEPLALQKYLVNNAKKIGLMVAGLAAQKYGKALDKEQ
EILVNIADIVSNLYAMESAVLRTEKAIKTTGLEKNKQKVLYTEVFCQEAFNEIEAHAKETLIAVENGDMLRMMLSSLRKL
TRHTPLNVIPKKREIAAKILEDERYTV

The query sequence (length=587) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3owa:C 587 587 1.0000 1.0000 1.0000 0.0 3owa:A, 3owa:B, 3owa:D
2 2z1q:B 549 585 0.5366 0.5738 0.5385 0.0 2z1q:A
3 8phe:A 551 534 0.3373 0.3593 0.3708 1.19e-99 8phe:B, 8phf:A, 8phf:B
4 7s7g:A 571 583 0.3356 0.3450 0.3379 5.93e-82 3b96:A, 2uxw:A
5 5ol2:F 378 400 0.2589 0.4021 0.3800 1.17e-81 5ol2:C
6 5lnx:D 374 388 0.2743 0.4305 0.4149 1.94e-81 5lnx:A, 5lnx:B, 5lnx:C, 5lnx:E, 5lnx:F, 5lnx:G, 5lnx:H
7 8ca1:B 589 595 0.3339 0.3328 0.3294 1.84e-79 8ca1:A
8 6fah:D 379 402 0.2538 0.3931 0.3706 3.45e-77 6fah:C
9 7y0a:C 387 410 0.2453 0.3721 0.3512 7.95e-76 1jqi:A, 1jqi:B, 8sgs:A, 8sgs:B, 8sgs:C, 8sgs:D, 2vig:A, 2vig:B, 2vig:C, 2vig:D, 2vig:E, 2vig:F, 2vig:G, 2vig:H, 7y0a:A, 7y0a:B, 7y0a:D, 7y0b:A, 7y0b:B, 7y0b:C, 7y0b:D
10 4l1f:A 380 399 0.2555 0.3947 0.3759 1.03e-72 4l1f:B
11 7szv:A 372 385 0.2504 0.3952 0.3818 2.23e-71 7szv:B
12 1ukw:A 379 396 0.2487 0.3852 0.3687 1.59e-70 1ukw:B
13 4n5f:A 378 393 0.2385 0.3704 0.3562 2.84e-70 4n5f:B
14 1rx0:A 384 396 0.2215 0.3385 0.3283 6.93e-68 1rx0:C, 1rx0:B, 1rx0:D
15 4m9a:B 376 395 0.2402 0.3750 0.3570 5.32e-67 4m9a:A
16 8sgr:A 393 398 0.2300 0.3435 0.3392 2.68e-65 1ivh:A, 1ivh:B, 1ivh:C, 1ivh:D, 8sgr:B, 8sgr:C, 8sgr:D
17 2a1t:C 388 396 0.2334 0.3531 0.3460 6.82e-65 2a1t:A, 2a1t:B, 2a1t:D, 1egc:A, 1egc:B, 1egc:C, 1egc:D, 1egd:A, 1egd:B, 1egd:C, 1egd:D, 1ege:A, 1ege:B, 1ege:C, 1ege:D, 4p13:A, 4p13:B, 4p13:C, 4p13:D, 8sgp:A, 8sgp:B, 8sgp:C, 8sgp:D, 1t9g:A, 1t9g:B, 1t9g:C, 1t9g:D
18 3mdd:A 385 396 0.2317 0.3532 0.3434 7.37e-64 3mdd:B, 3mde:A, 3mde:B, 1udy:A, 1udy:B, 1udy:C, 1udy:D
19 1buc:A 383 363 0.2385 0.3655 0.3857 1.23e-62 1buc:B
20 3pfd:C 369 370 0.2215 0.3523 0.3514 1.38e-62 3pfd:A, 3pfd:B, 3pfd:D
21 7w0j:E 382 401 0.2249 0.3455 0.3292 2.48e-62 8i4p:A, 8i4r:A, 7w0j:B, 7w0j:C, 7w0j:H
22 2dvl:A 370 381 0.2385 0.3784 0.3675 6.57e-59 2dvl:B
23 4irn:A 378 362 0.2010 0.3122 0.3260 1.97e-57 4irn:B, 4irn:C, 4irn:D, 4irn:E, 4irn:F, 4irn:G, 4irn:H
24 2pg0:A 380 390 0.2215 0.3421 0.3333 4.07e-57 2pg0:B
25 2d29:A 386 398 0.2436 0.3705 0.3593 6.97e-57 2d29:B
26 4iv6:B 383 394 0.2215 0.3394 0.3299 9.09e-57 4iv6:A
27 3gqt:C 385 398 0.2232 0.3403 0.3291 9.57e-57 3d6b:C, 3eon:C, 3gnc:A, 3gnc:B, 3gnc:C, 3gnc:D, 3gqt:A, 3gqt:B
28 3mpi:C 395 395 0.2147 0.3190 0.3190 2.91e-56 3mpi:A, 3mpi:B, 3mpi:D, 3mpj:B, 3mpj:A, 3mpj:D, 3mpj:E, 3mpj:F, 3mpj:G
29 4kto:A 377 362 0.2164 0.3369 0.3508 3.62e-52 4kto:C, 4kto:B, 4kto:D
30 2jif:A 381 390 0.2010 0.3097 0.3026 4.12e-52 2jif:C, 2jif:B, 2jif:D
31 8w0t:A 398 409 0.2249 0.3317 0.3227 9.55e-52 8w0t:B, 8w0t:C, 8w0t:D, 8w0u:A, 8w0u:B, 8w0u:C, 8w0u:D, 8w0z:A, 8w0z:B, 8w0z:C, 8w0z:D, 8w0z:E, 8w0z:F, 8w0z:G, 8w0z:H
32 7p9a:A 380 393 0.2266 0.3500 0.3384 1.11e-50 7p98:A, 7p98:B, 7p9a:B, 7p9x:A, 7p9x:B, 7p9x:C, 7p9x:D
33 2r0m:A 390 397 0.2112 0.3179 0.3123 1.50e-50 2r0n:A, 1siq:A, 1sir:A
34 5idu:C 405 400 0.2181 0.3160 0.3200 1.64e-49 5idu:A, 5idu:B, 5idu:D
35 3r7k:A 378 397 0.2266 0.3519 0.3350 1.66e-48 3r7k:B, 3r7k:C, 3r7k:D
36 3nf4:A 369 375 0.1959 0.3117 0.3067 1.97e-45 3nf4:B
37 6es9:A 545 408 0.2129 0.2294 0.3064 3.77e-43 6es9:B
38 5jsc:A 388 363 0.1976 0.2990 0.3196 1.90e-42 5jsc:B, 5jsc:C, 5jsc:D
39 2ix6:A 416 402 0.2010 0.2837 0.2935 1.95e-42 2ix5:A, 2ix5:B, 2ix5:C, 2ix5:D, 2ix6:C, 2ix6:F, 2ix6:B, 2ix6:E, 2ix6:D
40 6cxt:B 372 379 0.1857 0.2930 0.2876 3.20e-40 6cy8:B
41 2eba:A 380 404 0.2010 0.3105 0.2921 3.75e-40 2eba:D, 2eba:C, 2eba:E, 2eba:F, 2eba:G, 2eba:H, 2eba:I
42 3swo:A 388 385 0.1891 0.2861 0.2883 2.45e-39 3swo:D, 3swo:B, 3swo:C
43 6af6:A 383 359 0.1823 0.2794 0.2981 1.78e-38 5zw2:A, 5zw7:A, 5zw8:A
44 3sf6:A 387 394 0.2044 0.3101 0.3046 7.58e-38
45 3oib:A 381 389 0.2061 0.3176 0.3111 1.85e-37 3oib:B, 3p4t:A, 3p4t:B
46 7xp7:B 376 351 0.1806 0.2819 0.3020 1.28e-32 7xp7:A, 7xp7:C, 7xp7:D
47 8ciw:A 555 425 0.2095 0.2216 0.2894 1.46e-30 8ciw:B
48 5af7:B 391 386 0.1823 0.2737 0.2772 2.18e-27 5af7:A, 5ahs:A, 5ahs:B, 5ahs:C, 5ahs:E, 5ahs:F, 5ahs:D
49 6wy8:B 384 370 0.1755 0.2682 0.2784 1.74e-18 6wy8:D, 6wy9:A
50 1r2j:A 353 359 0.1533 0.2550 0.2507 9.36e-18
51 6kse:A 607 435 0.1891 0.1829 0.2552 1.62e-17 6kse:B
52 2wbi:B 398 334 0.1550 0.2286 0.2725 2.49e-17 2wbi:A
53 6ksa:B 611 463 0.1993 0.1915 0.2527 2.67e-17 6kpt:A, 6kpt:B, 6kri:A, 6kri:B, 6ks9:A, 6ks9:B, 6ksa:A, 6ksb:A, 6ksb:B, 6lpy:A, 6lpy:B, 6lq0:A, 6lq0:B, 6lq1:A, 6lq1:B, 6lq2:A, 6lq2:B, 6lq3:A, 6lq3:B, 6lq4:A, 6lq4:B, 6lq5:A, 6lq5:B, 6lq6:A, 6lq6:B, 6lq7:A, 6lq7:B, 6lq8:A, 6lq8:B
54 4y9j:B 593 342 0.1516 0.1501 0.2602 3.78e-17 4y9j:A, 4y9l:A, 4y9l:B
55 6u1v:B 389 386 0.1567 0.2365 0.2383 6.95e-17 6u1v:A, 6u1v:C, 6u1v:D
56 4x28:A 386 376 0.1670 0.2539 0.2606 2.25e-16 4x28:B
57 4hr3:A 407 421 0.1704 0.2457 0.2375 2.97e-16
58 8hk0:B 379 209 0.1073 0.1662 0.3014 1.86e-14 8hk0:A
59 6sd8:X 503 451 0.1840 0.2147 0.2395 2.09e-14 6sd8:A, 6sda:A, 6sda:B
60 3u33:A 540 286 0.1210 0.1315 0.2483 5.02e-14 3djl:A, 3u33:B, 3u33:C, 3u33:D, 3u33:E, 3u33:F, 3u33:G, 3u33:H, 3u33:I, 3u33:J, 3u33:K, 3u33:L
61 5z8t:A 395 343 0.1533 0.2278 0.2624 5.14e-12 5z8t:B, 5z8t:C
62 5ys9:A 692 345 0.1397 0.1185 0.2377 8.95e-12 5ys9:B
63 5ez3:B 541 271 0.1039 0.1128 0.2251 3.65e-11 5ez3:A, 5ez3:C, 5ez3:D
64 6wy8:C 364 380 0.1721 0.2775 0.2658 5.20e-11 6wy8:A, 6wy9:B
65 3mkh:A 426 430 0.1670 0.2300 0.2279 3.36e-10 3mkh:B, 3mkh:C, 3mkh:D
66 5y9d:A 687 328 0.1312 0.1121 0.2348 1.71e-08 5y9d:B
67 4zyj:D 392 376 0.1465 0.2194 0.2287 4.16e-07 4zyj:A, 4zyj:B, 4zyj:C
68 4x28:D 364 302 0.1363 0.2198 0.2649 5.76e-07 4x28:C
69 3d9d:A 432 139 0.0750 0.1019 0.3165 1.10e-06 2c0u:A, 2c0u:B, 2c0u:C, 2c0u:D, 2c12:A, 2c12:B, 2c12:C, 2c12:D, 2c12:E, 2c12:F, 3d9d:B, 3d9d:C, 3d9d:D, 3d9e:A, 3d9e:B, 3d9e:C, 3d9e:D, 3d9f:A, 3d9f:B, 3d9f:C, 3d9f:D, 3d9g:A, 3d9g:B, 3d9g:C, 3d9g:D, 3fcj:A, 3fcj:B, 3fcj:C, 3fcj:D, 2reh:A, 2reh:B, 2reh:C, 2reh:D, 2zaf:A, 2zaf:B, 2zaf:C, 2zaf:D
70 1w07:B 658 458 0.1687 0.1505 0.2162 6.77e-06 1w07:A
71 2fon:B 656 337 0.1295 0.1159 0.2255 1.73e-05 2fon:A, 2fon:C
72 3x0y:A 402 188 0.0801 0.1169 0.2500 3.10e-05 3x0y:F, 3x0y:C, 3x0y:E, 3x0y:B, 3x0y:D
73 5xdc:B 402 187 0.0818 0.1194 0.2567 1.11e-04 5xdb:A, 5xdb:B, 5xdb:C, 5xdb:D, 5xdc:A, 5xdc:C, 5xdc:D, 5xdd:A, 5xdd:B, 5xdd:C, 5xdd:D, 5xde:A, 5xde:B, 5xde:C, 5xde:D, 5xdg:A, 5xdg:B, 5xdg:C, 5xdg:D
74 1is2:A 637 451 0.1840 0.1695 0.2395 0.001 2ddh:A, 1is2:B
75 5k3i:A 661 315 0.1244 0.1104 0.2317 0.002 5k3i:B, 5k3i:C, 5k3i:D, 5k3i:E, 5k3i:F, 5k3i:G, 5k3i:H
76 7q86:A 612 337 0.1329 0.1275 0.2315 0.002 7q86:B
77 4kcf:A 407 357 0.1227 0.1769 0.2017 0.004 3m9v:A
78 4xvx:B 373 287 0.1073 0.1689 0.2195 0.009 4xvx:A
79 2rfq:A 388 196 0.0733 0.1108 0.2194 0.026 2rfq:B, 2rfq:C, 2rfq:D
80 5k3j:A 662 141 0.0664 0.0589 0.2766 0.26 5k3j:B
81 8zkk:B 202 34 0.0256 0.0743 0.4412 3.1 8zkm:B, 8zkm:C
82 2uzz:B 372 120 0.0528 0.0833 0.2583 4.2 2uzz:A, 2uzz:C, 2uzz:D
83 7f76:B 173 58 0.0341 0.1156 0.3448 9.7 7f76:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218