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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ATYAQALQSVPETQVSQLDNGLRVASEQSSQPTCTVGVWIDAGSRYESEKNNGAGYFVEHLAFKGTKNRPGNALEKEVES
MGAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNCSLEDSQIEKERDVILQELQENDTSMRDVVFNYLHATAFQGT
PLAQSVEGPSENVRKLSRADLTEYLSRHYKAPRMVLAAAGGLEHRQLLDLAQKHFSGLSGTYDEDAVPTLSPCRFTGSQI
CHREDGLPLAHVAIAVEGPGWAHPDNVALQVANAIIGHYDCTYGGGAHLSSPLASIAATNKLCQSFQTFNICYADTGLLG
AHFVCDHMSIDDMMFVLQGQWMRLCTSATESEVLRGKNLLRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAE
VDARVVREVCSKYFYDQCPAVAGFGPIEQLPDYNRIRSGMFWLR

The query sequence (length=444) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1be3:A 446 444 1.0000 0.9955 1.0000 0.0 2a06:A, 1bgy:A, 1bgy:M, 4d6t:N, 4d6u:A, 4d6u:N, 7dgq:k, 7dgq:w, 7dgr:k, 7dgr:w, 7dgs:k, 7dgs:w, 7dkf:A1, 7dkf:M1, 6fo0:N, 6fo0:A, 6fo2:N, 6fo2:A, 5luf:c, 5luf:l, 5nmi:N, 5nmi:A, 1pp9:A, 1ppj:A, 6qbx:a3, 6qc3:a1, 7tz6:A, 7tz6:N, 2ybb:a, 2ybb:A
2 7o3e:L 445 444 0.8761 0.8742 0.8761 0.0
3 8iao:Aa 412 436 0.8131 0.8762 0.8280 0.0 8iar:Aa, 8ibd:AA, 8ibd:Aa, 8ibg:AA, 8ibg:Aa
4 7jrg:A 487 442 0.4527 0.4127 0.4548 1.30e-148 8e73:A, 8e73:M, 7jrg:M, 7jrp:A, 7jrp:M
5 8bep:B 487 440 0.4572 0.4168 0.4614 7.16e-148 8bep:L, 8bpx:AB, 8bpx:BB, 8bq5:AB, 8bq5:BB, 8bq6:AB, 8bq6:BB
6 8q1b:A 443 440 0.4617 0.4628 0.4659 4.96e-132 8q1b:L
7 1hr6:D 443 392 0.3694 0.3702 0.4184 8.77e-107 1hr6:B, 1hr6:F, 1hr6:H, 1hr7:B, 1hr7:D, 1hr7:F, 1hr7:H, 1hr8:B, 1hr8:D, 1hr8:F, 1hr8:H, 1hr9:B, 1hr9:D, 1hr9:F, 1hr9:H
8 8e7s:A 431 443 0.3086 0.3179 0.3093 8.19e-52 8e7s:a, 8ec0:A, 8ec0:a
9 3hdi:A 414 418 0.2500 0.2681 0.2656 1.52e-47 3hdi:B
10 7v4y:A 402 407 0.2545 0.2811 0.2776 1.42e-27
11 5euf:B 416 275 0.1712 0.1827 0.2764 1.83e-26 5euf:A
12 1pp9:O 424 434 0.2320 0.2429 0.2373 4.76e-26 2a06:B, 4d6t:B, 4d6t:O, 4d6u:B, 4d6u:O, 7dgq:l, 7dgq:x, 7dgr:l, 7dgr:x, 7dgs:l, 7dgs:x, 6fo0:O, 6fo0:B, 6fo2:O, 6fo2:B, 1pp9:B, 1ppj:O, 1ppj:B, 6qbx:a2, 6qbx:a4, 6qc3:a2, 6qc3:a4, 7tz6:B, 7tz6:O
13 8ibd:AB 418 434 0.2162 0.2297 0.2212 6.90e-23 8iao:Ab, 8iar:Ab, 8ibd:Ab, 8ibg:AB, 8ibg:Ab
14 3amj:C 422 206 0.1374 0.1445 0.2961 4.20e-22 3amj:A
15 6ofs:A 905 216 0.1306 0.0641 0.2685 2.61e-15
16 1q2l:A 937 126 0.0811 0.0384 0.2857 7.27e-08
17 5cio:A 770 215 0.1261 0.0727 0.2605 4.06e-07 5cio:B
18 6b03:A 896 219 0.1171 0.0580 0.2374 1.50e-06 6b05:A, 6brs:A
19 4iof:A 932 204 0.1126 0.0536 0.2451 1.37e-05
20 2g49:A 970 213 0.1171 0.0536 0.2441 0.001 6b3q:A, 6b3q:B, 6b70:A, 6b70:B, 6bfc:A, 6bfc:B, 6byz:A, 6byz:B, 5cjo:A, 3cww:B, 3cww:A, 4dtt:A, 4dtt:B, 4dwk:A, 4dwk:B, 3e4a:A, 3e4a:B, 3e4z:A, 3e4z:B, 3e50:A, 3e50:B, 6eds:A, 6eds:B, 2g47:A, 2g47:B, 2g48:A, 2g48:B, 2g49:B, 2g54:A, 2g54:B, 2g56:A, 2g56:B, 4gs8:A, 4gs8:B, 4gsc:A, 4gsc:B, 4gsf:A, 4gsf:B, 3h44:A, 3h44:B, 3hgz:A, 3hgz:B, 4ifh:A, 4ifh:B, 2jbu:A, 2jbu:B, 2jg4:A, 2jg4:B, 7k1d:A, 7k1d:B, 7k1e:A, 7k1e:B, 7k1f:A, 7k1f:B, 4lte:A, 4lte:B, 4m1c:A, 4m1c:B, 6mq3:A, 6mq3:B, 3n56:A, 3n56:B, 3n57:A, 3n57:B, 4nxo:A, 4nxo:B, 3ofi:A, 3ofi:B, 3p7l:A, 3p7o:A, 4pes:A, 4pes:B, 4pf7:A, 4pf7:B, 4pf9:A, 4pf9:B, 4pfc:A, 4pfc:B, 4qia:A, 4qia:B, 3qz2:A, 3qz2:B, 4ral:A, 4ral:B, 4re9:A, 4re9:B, 7rze:A, 7rzf:A, 7rzi:A, 7rzi:B, 3tuv:A, 2wby:A, 2wby:B, 2wc0:A, 2wc0:B, 2wk3:A, 2wk3:B, 5wob:A, 5wob:B, 5wob:C, 5wob:D, 5wob:E, 5wob:F, 5wob:G, 5wob:H, 2ypu:A, 2ypu:B
21 3go9:A 458 243 0.1171 0.1135 0.2140 0.17
22 6f6t:B 677 185 0.1036 0.0679 0.2486 2.1 6f6t:A, 6hqf:A, 6hqf:B
23 6sgb:F1 889 80 0.0495 0.0247 0.2750 2.5 6sg9:F1, 6sga:F1
24 2nv9:B 372 62 0.0450 0.0538 0.3226 4.2 2nv9:A, 2nv9:C, 2nv9:D, 2nv9:E, 2nv9:F, 2nv9:G, 2nv9:H, 2nva:A, 2nva:B, 2nva:C, 2nva:D, 2nva:E, 2nva:F, 2nva:G, 2nva:H
25 3cur:H 545 87 0.0608 0.0495 0.3103 4.5 3cur:I, 3cur:J, 3cus:Q, 3cus:R, 3cus:S, 1frf:L, 3h3x:Q, 3h3x:R, 3h3x:S, 4ucq:Q, 4ucq:R, 4ucq:S, 4ucw:Q, 4ucw:R, 4ucw:S, 4ucx:Q, 4ucx:R, 4ucx:S, 4ud2:S, 4ud2:Q, 4ud2:R, 4ud6:Q, 4ud6:R, 4ud6:S, 4ue2:Q, 4ue2:R, 4ue2:S, 4ue6:R, 4ue6:Q, 4ue6:S, 4ueq:Q, 4ueq:R, 4ueq:S, 4ueq:T, 4ueq:U, 4ueq:V, 4uew:Q, 4uew:R, 4uew:S, 4upe:Q, 4upe:R, 4upe:S, 4upv:Q, 4upv:R, 4uql:Q, 4uql:R, 4uqp:Q, 4uqp:R, 4urh:Q, 4urh:S, 4urh:R, 1yqw:Q, 1yqw:R, 1yqw:S, 1yrq:H, 1yrq:I, 1yrq:J, 1yrq:K, 1yrq:M, 1yrq:N
26 4pof:A 255 75 0.0360 0.0627 0.2133 4.7 5iy0:A, 5iy0:B, 5iy0:C, 5iy0:D, 5iy0:E, 5iy0:F, 4pof:B, 4pof:C, 4pof:D, 4pof:E, 4pof:F, 4pog:A, 4pog:E, 4pog:F, 4pog:K, 4pog:L, 4pog:G, 4pog:H, 4pog:I, 4pog:J, 4pog:B, 4pog:C, 4pog:D, 4ywl:A, 4ywl:B, 4ywl:C, 4ywl:D, 4ywl:E, 4ywl:F, 4ywl:G, 4ywl:H, 4ywl:I, 4ywl:J, 4ywm:A, 4ywm:B, 4ywm:C, 4ywm:D, 4ywm:E, 4ywm:F, 4ywm:G, 4ywm:H, 4ywm:I, 4ywm:J
27 7nl1:D 400 126 0.0698 0.0775 0.2460 5.6 8bis:C, 8bis:A, 8biu:G, 8biu:A, 8biv:A, 8biv:E, 8biw:E, 8biw:A, 8bix:C, 8bix:A, 8biz:E, 8biz:A, 7nl1:A, 7nl1:B, 7nl1:C, 7nl1:E, 7nl1:F, 7nl1:G, 7nl1:H
28 6yji:A 477 56 0.0338 0.0314 0.2679 6.3 6yji:B
29 8ide:A 929 40 0.0338 0.0161 0.3750 6.7
30 6rgs:B 626 182 0.0991 0.0703 0.2418 7.1
31 6z0p:A 242 78 0.0518 0.0950 0.2949 7.1 6z0p:B
32 3vpb:B 282 76 0.0518 0.0816 0.3026 9.2 3vpb:A, 3vpb:C, 3vpb:D, 3vpc:A, 3vpc:B, 3vpc:C, 3vpc:D
33 5diy:A 463 40 0.0315 0.0302 0.3500 9.5 5diy:B
34 1icp:A 358 25 0.0225 0.0279 0.4000 9.5 3hgr:A, 3hgr:B, 1icp:B, 1icq:A, 1icq:B, 1ics:A, 1ics:B
35 6jjj:A 151 47 0.0293 0.0861 0.2766 9.9 6jjj:B, 6jjj:C, 6jjj:D, 6jjj:E, 6jjj:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218