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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ATTLYLTRHGETKWNVERRMQGWQDSPLTEKGRQDAMRLGKRLEAVELAAIYTSTSGRALETAEIVRGGRLIPIYQDERL
REIHLGDWEGKTHDEIRQMDPIAFDHFWQAPHLYAPQRGERFCDVQQRALEAVQSIVDRHEGETVLIVTHGVVLKTLMAA
FKDTPLDHLWSPPYMYGTSVTIIEVDGGTFHVAVEGDVSHIEEVKEV

The query sequence (length=207) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1h2e:A 207 207 1.0000 1.0000 1.0000 2.45e-154 1h2f:A
2 4ij6:A 207 170 0.2415 0.2415 0.2941 4.43e-20 4ij6:B
3 1k6m:A 432 205 0.2995 0.1435 0.3024 1.26e-17 1c7z:A, 1c7z:B, 1c80:A, 1c80:B, 1c81:A, 1fbt:A, 1fbt:B, 1k6m:B, 1tip:A, 1tip:B
4 2axn:A 451 204 0.3140 0.1441 0.3186 1.66e-17 5ajv:B, 5ajw:A, 5ajx:A, 5ajy:A, 5ajz:A, 5ak0:A, 4d4j:A, 4d4k:A, 4d4l:A, 4d4m:A, 2dwo:A, 2dwp:A, 6etj:A, 6hvh:A, 6hvi:A, 6hvj:A, 2i1v:B, 6ibx:A, 6iby:A, 6ibz:A, 6ic0:A, 4ma4:A, 3qpu:A, 3qpv:A, 3qpw:A
5 5htk:A 425 205 0.3285 0.1600 0.3317 1.17e-16 5hr5:A, 5htk:B
6 1bif:A 432 196 0.2802 0.1343 0.2959 2.43e-16 2bif:A, 2bif:B
7 1qhf:A 240 187 0.2850 0.2458 0.3155 2.34e-15 1bq3:D, 1bq3:A, 1bq4:A, 5pgm:E, 1qhf:B
8 4pza:B 217 137 0.2464 0.2350 0.3723 2.69e-15 4pza:A, 4qih:A, 4qih:B
9 5zr2:C 198 156 0.2174 0.2273 0.2885 2.00e-13 6m1x:C, 6m1x:D, 5zr2:A, 5zr2:B, 5zr2:D
10 7xb8:B 249 192 0.2464 0.2048 0.2656 1.87e-10 6isn:C, 8it4:A, 8it4:B, 8it5:C, 8it6:C, 8it7:C, 8it8:C, 8itb:C, 8itc:C, 8itd:C, 7xb7:B, 7xb7:C, 7xb8:C, 7xb9:B, 7xb9:C, 5y2i:B, 5y2u:B, 5y2u:C, 5y35:C, 5y64:C, 5y65:C, 1yfk:A, 1yjx:B, 1yjx:C, 1yjx:D, 1yjx:E, 1yjx:G, 1yjx:I, 1yjx:J, 1yjx:K, 1yjx:L, 5zrm:C, 5zs8:C
11 2h4z:A 255 197 0.2464 0.2000 0.2589 3.74e-10 2f90:A, 2f90:B, 2h4z:B, 2hhj:A, 2hhj:B, 7n3r:B, 7n3s:A, 7n3s:B, 7thi:A, 7thi:B
12 1e59:A 239 189 0.2609 0.2259 0.2857 9.26e-10
13 3gp5:A 248 97 0.1691 0.1411 0.3608 3.44e-08 3fdz:A, 3gp3:A, 3gp3:B, 3gp3:C, 3gp3:D, 3gp5:B, 3gw8:A, 3gw8:B
14 3lg2:A 269 184 0.2271 0.1747 0.2554 1.10e-05 3lg2:B, 3lg2:C, 3lg2:D, 3ll4:A, 3ll4:B, 3oi7:A, 3oi7:B, 3oi7:C, 3oi7:D
15 9emu:C 227 96 0.1401 0.1278 0.3021 1.36e-05 9emu:A, 9emu:B, 9emu:D
16 2b7y:A 181 52 0.0628 0.0718 0.2500 0.44 2b7y:C
17 3c7t:A 259 152 0.1691 0.1351 0.2303 0.46 3c7t:B, 3c7t:C, 3c7t:D
18 2dld:A 337 69 0.0966 0.0593 0.2899 1.9 2dld:B
19 4uy0:C 333 19 0.0531 0.0330 0.5789 2.2
20 8gdl:A 355 23 0.0531 0.0310 0.4783 3.9 8gdl:B
21 7mjc:A 493 42 0.0628 0.0264 0.3095 5.3 7mjc:B, 7mjd:A, 7mjd:B, 7rad:A, 7rad:B
22 4my0:C 392 46 0.0918 0.0485 0.4130 6.3 4my0:A, 4my0:E, 4my0:B, 4my0:D, 4my0:F
23 3ays:A 357 35 0.0628 0.0364 0.3714 7.3

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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