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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ATSNPAFDPKNLMQSEIYHFAQNNPLADFSSDKNSILTLSDKRSIMGNQSLLWKWKGGSSFTLHKKLIVPTDKEASKAWG
RSSTPVFSFWLYNEKPIDGYLTIDFGEKLISTSQAGFKVKLDFTGWRAVGVSLNNDLELGAKVDSIRFKAPSNVSQGEIY
IDRIMFSVDDARYQWSDYQVKTRLSEPEIQFHNVKPQLPVTPENLAAIDLIRQRLINEFVGKETNLALEENISKLKSDFD
ALNIHTLANGGTQGRHLITDKQIIIYQPENLNSQDKQLFDNYVILGNYTTLMFNISRAYVLEKDPTQKAQLKQMYLLMTK
HLLDQGFVKGSALVTTHHWGYSSRWWYISTLLMSDALKEANLQTQVYDSLLWYSREFKSSFDMKVSADSSDLDYFNTLSR
QHLALLLLEPDDQKRINLVNTFSHYITGALTQVPPGGKDGLRPDGTAWRHEGNYPGYSFPAFKNASQLIYLLRDTPFSVG
ESGWNNLKKAMVSAWIYSNPEVGLPLAGRHPFNSPSLKSVAQGYYWLAMSAKSSPDKTLASIYLAISDKTQNESTAIFGE
TITPASLPQGFYAFNGGAFGIHRWQDKMVTLKAYNTNVWSSEIYNKDNRYGRYQSHGVAQIVSNGSQLSQGYQQEGWDWN
RMQGATTIHLPLKDLDSPKPHTLMQRGERGFSGTSSLEGQYGMMAFDLIYPANLERFDPNFTAKKSVLAADNHLIFIGSN
INSSDKNKNVETTLFQHAITPTLNTLWINGQKIENMPYQTTLQQGDWLIDSNGNGYLITQAEKVNVSRQHQVSAENKNRQ
PTEGNFSSAWIDHSTRPKDASYEYMVFLDATPEKMGEMAQKFRENNGLYQVLRKDKDVHIILDKLSNVTGYAFYQPASIE
DKWIKKVNKPAIVMTHRQKDTLIVSAVTPDLNMTRQKAATPVTINVTINGKWQSSEVKYQVSGDNTELTFTSYFGIPQEI
KLSPLP

The query sequence (length=966) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7eip:A 966 966 1.0000 1.0000 1.0000 0.0 7eiq:A, 7eir:A, 7eis:A, 7yke:A
2 2q1f:A 991 1000 0.2629 0.2563 0.2540 6.12e-78 2q1f:B
3 2e22:A 752 515 0.1201 0.1543 0.2252 1.38e-13 1j0m:A, 1j0n:A, 1x1i:A, 1x1j:A
4 1cb8:A 674 366 0.0880 0.1261 0.2322 1.80e-12 1hm2:A, 1hm3:A, 1hmu:A, 1hmw:A
5 1rwc:A 754 363 0.0890 0.1141 0.2369 6.86e-11 1rwf:A, 1rwg:A, 1rwh:A
6 6f2p:A 1040 339 0.0735 0.0683 0.2094 8.67e-06
7 1i8q:A 814 110 0.0311 0.0369 0.2727 0.021 1lxm:A
8 2wda:A 742 273 0.0569 0.0741 0.2015 0.025
9 5jmd:A 646 104 0.0269 0.0402 0.2500 0.065 5jmf:A
10 1nf2:A 267 83 0.0290 0.1049 0.3373 0.28 1nf2:B, 1nf2:C
11 6v0t:A 402 125 0.0280 0.0672 0.2160 1.5 3mq3:A, 2pnq:A, 2pnq:B
12 4itb:A 453 57 0.0197 0.0419 0.3333 1.9 4ita:A, 4ita:B, 4itb:B, 3vz3:A, 3vz3:B
13 5fp1:A 701 94 0.0269 0.0371 0.2766 3.6
14 2dcn:A 308 124 0.0352 0.1104 0.2742 4.0 2dcn:B, 2dcn:C, 2dcn:D, 2dcn:E, 2dcn:F, 2dcn:G, 2dcn:H, 2dcn:I, 2dcn:J, 2dcn:K, 2dcn:L
15 1u7h:A 341 99 0.0259 0.0733 0.2525 4.0 1u7h:B, 1x7d:A, 1x7d:B
16 7nra:BBB 328 45 0.0166 0.0488 0.3556 5.4 7nra:AAA
17 3byj:A 440 82 0.0238 0.0523 0.2805 5.5 3byk:A, 3byn:A, 1oyg:A, 1pt2:A, 6pwq:A, 6pwq:B, 2vdt:A, 6vhq:A, 6vhq:B
18 4y9v:A 603 99 0.0300 0.0481 0.2929 6.8
19 8hjo:B 440 58 0.0166 0.0364 0.2759 7.6 8hjf:A, 8hjf:B, 8hjg:A, 8hjg:B, 8hjh:A, 8hjh:B, 8hjk:A, 8hjl:A, 8hjl:B, 8hjn:A, 8hjn:B, 8hjo:A, 8hjp:A, 8hjp:B, 8j66:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218