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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ATRLDRLVTILETGSTRLIRDTAVNQLADWQKQHPEELFNLLSRVVPYLRHKDWETRTTAAKAIGKIIENAPLYDPNNFF
RLESLDVATIVKYGRPLLRGGPVDYNLAALDPQKRLAHLKKTLNGRLGLLGRVFEDEEMPGAEWPFERLCEFLKVDLFDP
QWETRHGAAMGLREVIRVHGAGAGRRRGKTRKENNDLNRQWLDDLAYRLLCVLMLDKFTDYSSDTSVAPIRETVGQTLGA
VLRHISVESVHAIYRLLYCMVTGMVGLRYVVAVRKDLLLQDGDMIDGVVRCVMQGLGDIDDDVRSVSAATLIPMAKEFVM
MRRSALDSLINIVWESLSNLGDDLSASTGKIMDLLATLCSFPEVLEAMKVSASQDEERSFTLLVPRLYPFLRHTITSVRL
AVLKALMTFANLGGETSQGWLNGRILRLIFQNIIVERDQDTLNMSLELWTTLVRRLAARDPAILADEFEAHAEPMMQLAL
HPIGVPRHPIPMNPALFQKPVDGHMIQGEVDLVGVDVLIRSRISAAKAMGLIMSFIPTPRLASYDTAVLQALSSPYASTQ
LAAAMVIDEYAKNCSTPEVASRFIEPLQKIIDLERPSHYRDLVTYVQRVRSASQQLINLFRDHGKVSQGKLPTLAVVVQG
EPEAGPGAFSIANAEKVVNEDFERLKRLMAPGQRLIALPQLNEAREQTVEVIEEAKAAKEARDARIKAAAACALVAMKVL
PKKPSPLIKAIMDSIKTEENQELQSRSAATIARLVQLFTESGRRGPAEKVVANLVKFSCVEVAETPEFPIHAHKTNVILS
MQKEEDRVDHPDAVKYAREAKAARITRRGAKEALEILSKNFGAELLERVPTLRTFMEEPLVRAFSGDLPPEARDPENAFG
QEIVDAMSVIRTMTPTLHPALHPFVMQQVPLVIKALRSDLSVFRYMAAKCMATICSVITVDGMTALVEKVLPSINNPLDL
SFRQGAIEVIYHLIAVMGDAILPYVIFLIVPVLGRMSDSDNQIRLIATTSFATLVKLVPLEAGIPDPPGLSEELLKGRDR
ERTFIAQLLDPKKIEPFKIPVAIKAELRSYQQEGVNWLAFLNKYHLHGILCDDMGLGKTLQTICIVASDHHQRAEEFART
GAPEVRKLPSLIICPPTLSGHWQQEIKTYAPFLTVTAYVGSPAERRAMKDSLDKTDIVITSYDVCRNDIDVIEKYNWNYC
VLDQGHLIKNPKAKITLAVKRLTSNHRLILTGTPIQNNVLELWSLFDFLMPGFLGAEKVFLDRFAKPIANSRYSKASSKE
QEAGALAIEALHKQVLPFLLRRLKEE

The query sequence (length=1306) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7z7n:E 1306 1306 1.0000 1.0000 1.0000 0.0
2 7zke:E 1623 1336 0.9923 0.7985 0.9701 0.0
3 7z8s:E 1514 1313 0.9250 0.7979 0.9200 0.0 7zb5:E, 7zb5:H
4 8b3f:b 534 256 0.0773 0.1891 0.3945 4.11e-51 8b3d:b, 7oo3:b, 7oob:b, 7oop:b, 7opc:b, 7opd:b
5 8tvy:M 558 257 0.0766 0.1792 0.3891 1.02e-45 5vvr:M
6 1z63:A 468 245 0.0758 0.2115 0.4041 1.29e-43 1z63:B
7 6vz4:K 616 251 0.0658 0.1396 0.3426 1.53e-41 6kw3:Y, 6kw4:Y, 6kw5:Q
8 8x19:I 864 249 0.0681 0.1030 0.3574 5.48e-41 8x1c:I
9 6tda:S 783 251 0.0658 0.1098 0.3426 1.88e-40
10 6ne3:W 461 251 0.0681 0.1931 0.3546 1.20e-39 8v4y:W, 8v6v:W, 8v6v:X, 8v7l:W
11 6uxw:A 778 251 0.0666 0.1118 0.3466 1.55e-39 7egp:A, 6iy2:O, 6iy3:O, 6uxv:A, 5x0x:O, 5x0y:O, 5z3l:O, 5z3o:O, 5z3u:O, 5z3v:O
12 6gej:M 688 251 0.0697 0.1323 0.3625 6.15e-39 6gen:M
13 6pwf:K 454 250 0.0628 0.1806 0.3280 1.22e-38
14 7vdv:A 809 243 0.0689 0.1112 0.3704 1.38e-38 7vdt:A
15 6eg2:A 619 248 0.0666 0.1405 0.3508 3.09e-38 6eg3:A
16 8he5:O 516 251 0.0658 0.1667 0.3426 8.09e-38
17 6fml:G 731 257 0.0636 0.1135 0.3230 9.97e-38 8av6:G
18 7x3t:V 792 252 0.0658 0.1086 0.3413 1.84e-37 6iro:L, 6jyl:K, 6k1p:K, 7x3w:K, 2y9z:A
19 7ux9:P 468 248 0.0681 0.1902 0.3589 3.73e-37
20 5hzr:A 552 251 0.0613 0.1449 0.3187 1.59e-36
21 7y8r:I 732 243 0.0666 0.1189 0.3580 3.18e-36
22 8kcc:K 508 252 0.0689 0.1772 0.3571 7.87e-36 8j90:K, 8kcb:K, 8wh5:K, 8wh8:K, 8wh9:K, 8wha:K, 8wha:L
23 8atf:G 442 257 0.0613 0.1810 0.3113 4.20e-35 8oo9:G, 8oos:G
24 7epu:B 748 247 0.0643 0.1123 0.3401 1.88e-34 8b0a:K, 7enn:K, 7otq:K
25 8oo7:G 704 231 0.0582 0.1080 0.3290 7.87e-34 8oop:G
26 8x15:I 792 194 0.0551 0.0909 0.3711 4.27e-33
27 7zi4:G 682 241 0.0605 0.1158 0.3278 6.82e-31
28 9gd1:W 849 254 0.0590 0.0907 0.3031 1.14e-28
29 6g0l:M 855 254 0.0559 0.0854 0.2874 1.51e-28 7nkx:W, 5o9g:W
30 7tn2:W 895 259 0.0605 0.0883 0.3050 1.71e-28 9gd2:W, 9gd3:W
31 6ftx:W 878 259 0.0574 0.0854 0.2896 2.32e-28 6g0l:W, 5j70:A, 5j70:B, 3mwy:W, 3ted:A
32 7xyf:K 656 253 0.0582 0.1159 0.3004 1.26e-25 7xyg:K
33 1z3i:X 644 308 0.0689 0.1398 0.2922 1.30e-25
34 6ryr:W 708 265 0.0613 0.1130 0.3019 1.47e-25 2l75:A, 1mm2:A, 6q3m:D, 6ryu:W, 6ryu:V
35 9c57:G 878 181 0.0429 0.0638 0.3094 7.07e-15
36 6l8n:A 810 228 0.0475 0.0765 0.2719 1.27e-12
37 7r76:A 1834 240 0.0436 0.0311 0.2375 0.016 7r77:A
38 7r78:A 1880 103 0.0214 0.0149 0.2718 0.038
39 8sp4:A 859 159 0.0329 0.0501 0.2704 0.080 8spg:A
40 3wvc:A 169 63 0.0145 0.1124 0.3016 2.3 3wvc:B
41 7vl3:A 707 51 0.0138 0.0255 0.3529 2.6 7vkx:A, 7vkx:B, 7vky:A, 7vky:B, 7vkz:A, 7vkz:B, 7vl0:A, 7vl0:B, 7vl1:A, 7vl1:B, 7vl2:A, 7vl2:B, 7vl3:B, 7vl4:A, 7vl4:B, 7vl5:B, 7vl6:A, 7vl6:B, 7vl7:A, 7vl7:B, 7x87:A, 7x87:B
42 6rfl:Y 600 49 0.0145 0.0317 0.3878 5.4 7aoh:Y, 8c8h:Y
43 4dyk:A 437 62 0.0130 0.0389 0.2742 5.6 4dyk:B, 4gbd:A, 4gbd:B
44 2isv:A 298 54 0.0130 0.0570 0.3148 5.9 3gak:A
45 4ajw:A 765 134 0.0283 0.0484 0.2761 7.1 4v0i:A
46 8xvg:L 3485 129 0.0268 0.0100 0.2713 7.4 8xvv:L
47 7a9w:A 513 85 0.0184 0.0468 0.2824 8.9 7a9x:A
48 7mq9:LM 2005 99 0.0214 0.0140 0.2828 9.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218