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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ATRIAILGAGPSGMAQLRAFQSAQEKGAEIPELVCFEKQADWGGQWNYTWRTGLDENGEPVHSSMYRYLWSNGPKECLEF
ADYTFDEHFGKPIASYPPREVLWDYIKGRVEKAGVRKYIRFNTAVRHVEFNEDSQTFTVTVQDHTTDTIYSEEFDYVVCC
TGHFSTPYVPEFEGFEKFGGRILHAHDFRDALEFKDKTVLLVGSSYSAEDIGSQCYKYGAKKLISCYRTAPMGYKWPENW
DERPNLVRVDTENAYFADGSSEKVDAIILCTGYIHHFPFLNDDLRLVTNNRLWPLNLYKGVVWEDNPKFFYIGMQDQWYS
FNMFDAQAWYARDVIMGRLPLPSKEEMKADSMAWREKELTLVTAEEMYTYQGDYIQNLIDMTDYPSFDIPATNKTFLEWK
HHKKENIMTFRDHSYRSLMTGTMAPKHHTPWIDALDDSLEAYLSD

The query sequence (length=445) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2xlr:C 452 445 0.9933 0.9779 0.9933 0.0 8b2d:A, 8b2d:B, 2vq7:A, 2vq7:B, 2vq7:C, 2vq7:D, 2vqb:A, 2vqb:B, 2vqb:C, 2vqb:D, 2xlp:A, 2xlp:B, 2xlp:C, 2xlp:D, 2xlr:A, 2xlr:B, 2xlr:D, 2xls:A, 2xls:B, 2xls:C, 2xls:D, 2xlt:A, 2xlt:B, 2xlt:C, 2xlt:D, 2xlu:A, 2xlu:B, 2xlu:C, 2xlu:D, 2xve:B, 2xve:C, 2xvf:A, 2xvf:B, 2xvf:C, 2xvh:A, 2xvh:B, 2xvh:C, 2xvi:A, 2xvi:B, 2xvi:C, 2xvj:A, 2xvj:B, 2xvj:C
2 6hns:A 443 442 0.7551 0.7585 0.7602 0.0 6hns:B
3 5gsn:A 445 442 0.6449 0.6449 0.6493 0.0 5gsn:B, 5gsn:C, 5gsn:D, 5ipy:A, 5ipy:B, 5iq1:A, 5iq1:B, 5iq4:A, 5iq4:B
4 6kbw:A 446 441 0.5551 0.5538 0.5601 0.0 6kbw:B
5 7d4k:A 444 443 0.5371 0.5383 0.5395 0.0 7d4k:B, 7d4m:A, 7d4m:B, 7d4n:A, 7d4n:B
6 5nmx:D 409 416 0.3169 0.3447 0.3389 6.62e-63 5nmw:A, 5nmw:B, 5nmw:C, 5nmw:D, 5nmx:A, 5nmx:B, 5nmx:C
7 6wpu:A 439 381 0.2652 0.2688 0.3097 4.64e-39
8 2gv8:A 442 398 0.2382 0.2398 0.2663 1.88e-32 2gv8:B, 2gvc:A, 2gvc:B, 2gvc:D, 2gvc:E, 1vqw:A, 1vqw:B
9 6sek:A 504 460 0.2809 0.2480 0.2717 3.03e-30 6sek:B
10 6se3:D 528 229 0.1663 0.1402 0.3231 8.44e-25 6se3:A, 6se3:B, 6se3:C, 6se3:E, 6se3:F
11 6se3:D 528 146 0.0944 0.0795 0.2877 1.74e-07 6se3:A, 6se3:B, 6se3:C, 6se3:E, 6se3:F
12 6sem:B 530 245 0.1685 0.1415 0.3061 1.45e-24 6sem:A, 6sem:C, 6sem:D, 6sf0:B, 6sf0:A, 6sf0:C, 6sf0:D
13 6sem:B 530 134 0.0989 0.0830 0.3284 5.93e-09 6sem:A, 6sem:C, 6sem:D, 6sf0:B, 6sf0:A, 6sf0:C, 6sf0:D
14 7al4:D 524 231 0.1730 0.1469 0.3333 4.06e-24 7al4:C, 7al4:B, 7al4:A
15 7al4:D 524 146 0.0854 0.0725 0.2603 0.002 7al4:C, 7al4:B, 7al4:A
16 8odw:A 612 213 0.1191 0.0866 0.2488 5.15e-12 8odw:B
17 6jdk:B 516 229 0.1258 0.1085 0.2445 5.38e-09 6jdk:A
18 1w4x:A 533 223 0.1258 0.1051 0.2511 3.17e-08 4c74:A, 4c77:A, 4d03:A, 4d04:A, 4ovi:A, 2ylr:A, 2yls:A, 2ylt:A, 2ylw:A, 2ylx:A, 2ylz:A, 2ym1:A, 2ym2:A
19 7v4x:A 529 206 0.1101 0.0926 0.2379 1.08e-07 6a37:A, 7v50:A, 7v51:A
20 6gqi:A 529 216 0.1169 0.0983 0.2407 5.47e-07 6gqi:B, 5m0z:A, 5m10:A, 7v8o:A, 7v8o:B, 7v8r:A, 7v8s:A, 7v8s:B
21 4aos:A 523 206 0.1124 0.0956 0.2427 1.28e-05 4aox:A, 4ap1:A, 4ap3:A
22 3uoz:A 540 214 0.1124 0.0926 0.2336 1.36e-05 3uov:A, 3uov:B, 3uox:A, 3uox:B, 3uoy:A, 3uoy:B, 3uoz:B, 3up4:A, 3up4:B, 3up5:A, 3up5:B
23 4usr:A 357 55 0.0427 0.0532 0.3455 3.74e-05
24 4usr:A 357 65 0.0449 0.0560 0.3077 5.3
25 7a76:A 326 229 0.1393 0.1902 0.2707 4.01e-05 7a76:B, 7a76:C, 7a76:D
26 4c5o:D 333 158 0.0899 0.1201 0.2532 7.28e-05 4a9w:A, 4a9w:B, 4c5o:A, 4c5o:B, 4c5o:C, 4c5o:E, 4c5o:F, 4c5o:G, 4c5o:H
27 6er9:A 531 207 0.0989 0.0829 0.2126 7.29e-05 6er9:B, 6era:A, 6era:B, 3gwd:A, 3gwf:A, 4rg3:A, 4rg4:A, 3ucl:A
28 2cdu:A 451 96 0.0629 0.0621 0.2917 1.31e-04 2cdu:B
29 5j7x:A 527 209 0.1101 0.0930 0.2344 1.70e-04
30 4usq:F 341 190 0.0854 0.1114 0.2000 3.64e-04 4usq:A
31 5mq6:A 636 131 0.0742 0.0519 0.2519 0.001
32 6y48:B 538 228 0.1146 0.0948 0.2237 0.003 6y48:A, 6y48:C, 6y48:D
33 8acs:A 598 99 0.0584 0.0435 0.2626 0.012 8acs:B, 8acs:C, 8acs:D
34 6ruz:A 443 54 0.0404 0.0406 0.3333 0.031 6ruz:B, 6ruz:C, 6ruz:D, 6rvb:A, 6rvb:B, 6rvb:C, 6rvb:D, 6rvh:A, 6rvh:B, 6rvh:C, 6rvh:D
35 3ict:A 557 62 0.0427 0.0341 0.3065 0.094 3icr:A, 3icr:B, 3ics:A, 3ics:B, 3ict:B
36 8c3m:A 346 160 0.0966 0.1243 0.2687 0.34 8c3m:B, 6gar:A, 6gar:B
37 1ho5:A 525 29 0.0315 0.0267 0.4828 2.7 1ho5:B, 1hp1:A, 1hpu:A, 1hpu:B, 1hpu:C, 1hpu:D, 1oi8:A, 1oi8:B, 1ush:A, 2ush:A, 2ush:B, 4wwl:A
38 5er0:A 450 87 0.0607 0.0600 0.3103 2.8 5er0:B, 5er0:C, 5er0:D, 5vn0:A, 5vn0:B, 5vn0:C, 5vn0:D, 5vn0:E, 5vn0:F, 5vn0:G, 5vn0:H, 5voh:A, 5voh:B, 5voh:C, 5voh:D
39 7a7b:A 323 195 0.1079 0.1486 0.2462 3.1 7a7b:B, 7a7b:C, 7a7b:D, 7a7b:E, 7a7b:F, 7a7b:H, 7apr:A, 7apr:B, 7apr:C, 7apr:D, 7apr:E, 7apr:F, 7apr:H
40 5bju:A 340 32 0.0315 0.0412 0.4375 4.7 5bju:B, 5bjv:A, 5bjv:B, 5bjw:A, 5bjw:B, 5bjx:A, 5bjx:B, 5bjy:A, 5bjy:B
41 3r9u:A 314 86 0.0494 0.0701 0.2558 6.5 3r9u:B
42 6wmr:Z 470 82 0.0584 0.0553 0.3171 6.7 6wmt:Z

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218