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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAINTDGQALNLSKAESKIQIGEKLTRGLGAGANPEIGKKAAEESREQIED
AIQGADMVFVTSGMGGGTGTGAAPVVAKIAKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDTLIVIPNDRLLD
IVDKSTPMMEAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIMSNQGSALMGIGVSSGENRAVEAAKKAISSPLLE
TSIVGAQGVLMNITGGESLSLFEAQEAADIVQDAADEDVNMIFGTVINPELQDEIVVTVIATGFD

The query sequence (length=305) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4m8i:A 311 305 0.9869 0.9678 0.9869 0.0 4dxd:A, 5h5g:A, 5h5g:B, 5h5h:A, 5h5i:A, 8htb:A, 6kvp:A, 6kvq:A, 5mn4:A, 5mn5:A, 5mn5:B, 5mn6:A, 5mn6:B, 5mn7:A, 5mn7:B, 5mn8:B, 5mn8:A, 7ohh:A, 7ohk:A, 7ohl:A, 7ohn:A, 7oi2:A, 7oja:A, 7ojb:A, 7ojc:A, 7ojd:A, 7ojz:A, 7on2:A, 7on3:A, 7on4:A, 6rvm:A, 6rvm:B, 6rvm:C, 6rvn:A, 6rvp:A, 6rvq:A, 6si9:A, 3vo8:A, 3vo8:B, 3voa:A, 3vob:A, 3wgj:A, 3wgj:B, 3wgk:A, 3wgk:B, 3wgl:A, 3wgl:B, 3wgm:A, 3wgm:B, 3wgn:A, 3wgn:B, 5xdt:A, 5xdu:A, 5xdv:A, 5xdw:A, 6yd1:A, 6yd5:A, 6yd6:A
2 2rhl:B 315 304 0.8033 0.7778 0.8059 7.66e-156 2rhl:A, 2rho:A, 2rho:B, 4u39:B, 4u39:E, 4u39:F, 4u39:G
3 4u39:D 280 291 0.7180 0.7821 0.7526 1.28e-132 4u39:H, 4u39:I
4 7yop:B 304 304 0.5934 0.5954 0.5954 6.46e-121 8grw:A, 8grw:B, 7yop:A, 7ysz:A, 7ysz:B
5 5zue:A 309 291 0.6000 0.5922 0.6289 6.00e-118 4kwe:A, 4kwe:B, 4kwe:C, 2q1y:A, 1rlu:A, 1rq7:A, 5v68:B, 5v68:E, 6y1u:A, 6y1u:B, 6y1v:A, 6y1v:B, 6ym1:A, 6ym9:A
6 2vaw:A 315 292 0.5148 0.4984 0.5377 9.12e-95 1ofu:A, 1ofu:B
7 1w5f:A 315 305 0.5049 0.4889 0.5049 6.69e-91 1w5f:B
8 8h1o:A 314 291 0.4951 0.4809 0.5189 5.83e-90 8gzv:A, 8gzw:A, 8gzw:C, 8gzw:E, 8gzx:A, 8gzy:A, 8gzy:C, 8gzy:E, 8ibn:A, 8ibn:B, 8ibn:C, 8ibn:D, 6ll5:A, 6ll6:A, 6umk:A, 6unx:A
9 1w58:1 337 303 0.4951 0.4481 0.4983 1.61e-81 1fsz:A, 2vap:A, 1w5a:A, 1w5a:B, 1w5b:A, 1w5b:B, 1w5e:A, 1w5e:B, 1w5e:C, 1w5e:D, 1w5e:E, 1w5e:F, 1w5e:G, 1w5e:H, 1w5e:I
10 2r6r:1 323 293 0.4295 0.4056 0.4471 1.22e-74 2r75:1
11 3zid:A 360 261 0.2262 0.1917 0.2644 3.37e-09 3zid:B
12 4b46:A 330 169 0.1770 0.1636 0.3195 2.24e-04
13 4b45:A 334 202 0.1738 0.1587 0.2624 0.005
14 4xcq:A 303 110 0.1049 0.1056 0.2909 0.039
15 5ycd:B 193 83 0.0787 0.1244 0.2892 1.2 5x6k:A, 5x6k:B, 5x6l:A, 5x6l:B, 5xru:A, 5xru:B, 5xz2:A, 5xz2:B, 5ycb:A, 5ycb:B, 5ycc:A, 5ycc:B, 5ycd:A, 5ycf:B, 5ycf:A
16 5ysc:A 255 20 0.0328 0.0392 0.5000 1.9
17 6kbn:C 504 75 0.0754 0.0456 0.3067 2.4 6kbm:A, 6kbn:A
18 4rnh:A 423 93 0.0885 0.0638 0.2903 2.6
19 5jiz:A 151 53 0.0492 0.0993 0.2830 3.6 6bq8:A, 5bv6:A, 5jix:A
20 5l22:B 540 53 0.0623 0.0352 0.3585 5.1 5l22:A
21 6gos:1 284 47 0.0459 0.0493 0.2979 5.3 6gos:2, 6grg:1, 6grg:2, 6grh:1, 6grh:2, 6gri:1, 6gri:2
22 8e73:FD 122 44 0.0426 0.1066 0.2955 6.5
23 3jz4:A 481 55 0.0721 0.0457 0.4000 6.8 3jz4:B, 3jz4:C, 3jz4:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218