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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ATKLFPKFSQGLAQDPTTRRIWFGLAVAHDFESHDGMTEENLYQKIFASHFGQLAIIFLWTSGNLFHVAWQGNFEQWGAD
PIHVRPIAHAIWDPHFGQPAVEAFTRGGASGPVNISTSGVYQWWYTIGMRTNQDLYVGSVFLALVSAIFLFASWLHLQPS
FTPSLSWFKDAESRLNHHLSGLFGVSSLAWTGHLVHVAIPESRGKHVGWDNFLTQLPHPQGLTPFWTGNWAAYAQNPDSA
SHVFGTSDGAGEAILTFLGGFHPQTQSLWLTDMAHHHLAIAVIFIVAGHMYRTNFGIGHRMSAILDAHVAPSGRLGAGHK
GLFETVNNSLHFQLGLALASVGTICSLVAQHMYSLPPYAFLANDFTTQASLYTHHQYIAGFIMCGAFAHGAIFWIRDYDP
EQNKGNVLARMLDHKEAIISHLSWVSLFLGFHTLGLYVHNDVMQAFGTPEKQILIEPVFAQWIQAAHGKAFYGFDLLLSS
SSSSAASASQTLWLPGWLDAINNNQNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCD
GPGRGGTCDISAYDAFYLAVFWMLNTIGWVTFYFHWKHLTLWQGNVSQFDESSTYLMGWLRDYLWLNSSQLINGYNPFGM
NSLSVWAWIFLFGHLVYATGFMFLISWRGYWQELIETLVWAHEKTPLANLVYWKDKPVALSIVQARLVGLTHFSVGYVFT
YAAFLIASTSGK

The query sequence (length=732) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7d0j:B 734 732 0.9331 0.9305 0.9331 0.0 7a4p:B, 7bgi:B, 7blx:B, 8cmo:B, 7dz7:B, 7dz8:B, 8h2u:B, 6ijj:B, 6ijo:B, 6jo5:B, 6jo6:B, 6qph:B, 7r3k:B, 6rhz:B, 6sl5:B, 7wyi:B, 7wzn:B, 6yxr:B, 7zq9:B, 7zqc:B, 7zqd:B, 7zqd:B2, 6zzx:B, 6zzy:B
2 6igz:B 733 732 0.8716 0.8704 0.8716 0.0
3 7yca:B 732 732 0.8593 0.8593 0.8593 0.0
4 7y5e:BN 732 728 0.8265 0.8265 0.8310 0.0 7y5e:B2, 7y7a:B7, 7y7a:Bo, 7y7b:B, 7y8a:B
5 7wfd:AB 734 728 0.8402 0.8379 0.8448 0.0 8bcv:B, 8bcw:B, 7dkz:B, 7ew6:B, 7ewk:B, 7f9o:B, 7f9o:f, 8htu:B, 8j6z:B, 8j7a:B, 8j7b:B, 7ksq:B, 7kux:B, 6l35:B, 5l8r:B, 3lw5:B, 2o01:B, 4rku:B, 7wfe:BB, 7wg5:AB, 7wg5:BB, 8wgh:B, 2wsc:B, 2wse:B, 2wsf:B, 4xk8:B, 4xk8:b, 7xqp:B, 4y28:B, 6yac:B, 6yez:B, 5zji:B, 6zoo:B, 6zxs:B
6 8wm6:B 732 728 0.8074 0.8074 0.8118 0.0 8wmj:B, 8wmv:B, 8wmw:B
7 6kif:B 733 732 0.8210 0.8199 0.8210 0.0 6kif:H, 6kif:f, 6kig:B, 6kig:H, 6kig:f
8 6vpv:B 737 737 0.8265 0.8209 0.8209 0.0 8am5:b, 8asl:b, 8asp:b, 6hqb:B, 4kt0:B, 4l6v:B, 4l6v:b, 4l6v:2, 6nwa:B, 6nwa:b, 6nwa:G, 7o1v:B, 5oy0:B, 5oy0:b, 5oy0:2, 7umh:B, 7umh:G, 7umh:b, 6uzv:B, 6uzv:b, 6uzv:2, 6vpv:b, 6vpv:2
9 7blz:B 731 732 0.8074 0.8085 0.8074 0.0 6fos:B, 8wey:B, 5zgb:B, 5zgh:B
10 6kmw:aB 740 740 0.8224 0.8135 0.8135 0.0 6kmw:cB, 6kmw:bB
11 6ly5:b 732 732 0.8019 0.8019 0.8019 0.0 6l4u:B
12 7fix:B1 740 739 0.8128 0.8041 0.8051 0.0 7bw2:B, 4fe1:B, 7fix:B2, 7fix:B3, 1jb0:B, 6k33:aB, 6k33:bB, 6k33:cB, 7m75:B, 7m76:B, 7m78:B, 3pcq:B, 6pfy:H, 6pfy:B, 6pfy:Z, 6pgk:H, 6pgk:B, 6pgk:Z, 6tra:B, 6trc:B, 6trc:b, 6trc:2, 6trd:B, 6trd:b, 6trd:2, 5zf0:B1, 5zf0:B2, 5zf0:B3, 5zf0:B4, 5zf0:B6, 5zf0:B5
13 7qco:B 734 732 0.7964 0.7943 0.7964 0.0 7qco:G, 7qco:g, 7qco:b
14 7dr0:B 706 731 0.7937 0.8229 0.7948 0.0 7dr1:B, 7dr2:aB, 7dr2:bB, 7dr2:cB, 7dr2:dB
15 6lu1:B 713 735 0.8005 0.8219 0.7973 0.0
16 6k61:B 740 739 0.7964 0.7878 0.7889 0.0 6jeo:aB, 6jeo:bB, 6jeo:cB, 6jeo:dB, 6k61:b, 6tcl:B1, 6tcl:B2, 6tcl:B, 6tcl:BB, 7y3f:B
17 7lx0:H 739 739 0.7678 0.7605 0.7605 0.0 7lx0:b, 7lx0:B, 6pnj:H, 6pnj:B, 6pnj:b
18 6kmx:aB 727 735 0.7637 0.7689 0.7605 0.0 6kmx:bB, 6kmx:cB
19 7s3d:B 742 742 0.7568 0.7466 0.7466 0.0 7s3d:H, 7s3d:b
20 7f4v:aB 725 727 0.7158 0.7228 0.7208 0.0 7f4v:bB, 7f4v:cB
21 7dwq:B 659 726 0.6831 0.7587 0.6887 0.0 7coy:aB, 7coy:bB, 7coy:cB
22 5l8r:A 743 753 0.4686 0.4616 0.4555 0.0 8bcv:A, 8bcw:A, 7dkz:A, 7ew6:A, 7ewk:A, 7f9o:A, 7f9o:e, 8htu:A, 8j6z:A, 8j7a:A, 8j7b:A, 7ksq:A, 7kux:A, 6l35:A, 3lw5:A, 2o01:A, 4rku:A, 7wfd:AA, 7wfe:BA, 7wg5:AA, 7wg5:BA, 8wgh:A, 2wsc:A, 2wse:A, 2wsf:A, 4xk8:A, 4xk8:a, 7xqp:A, 4y28:A, 6yac:A, 6yez:A, 5zji:A, 6zoo:A, 6zxs:A
23 7yca:A 742 752 0.4549 0.4488 0.4428 0.0 7a4p:A, 7bgi:A, 7blx:A, 8cmo:A, 7d0j:A, 7dz7:A, 7dz8:A, 8h2u:A, 6ijj:A, 6ijo:A, 6jo5:A, 6jo6:A, 7r3k:A, 7wyi:A, 7wzn:A, 7zq9:A, 7zqc:A, 7zqd:A, 7zqd:A2, 6zzx:A, 6zzy:A
24 7y5e:AN 745 753 0.4536 0.4456 0.4409 0.0 7y5e:A2, 7y7a:A7, 7y7a:Ao
25 6tra:A 746 757 0.4563 0.4477 0.4412 0.0 4fe1:A, 7fix:A1, 7fix:A2, 7fix:A3, 1jb0:A, 6k33:aA, 6k33:bA, 6k33:cA, 6lu1:A, 7m75:A, 7m76:A, 7m78:A, 3pcq:A, 6pfy:A, 6pfy:G, 6pfy:Y, 6pgk:A, 6pgk:G, 6pgk:Y, 6trc:A, 6trc:a, 6trc:1, 6trd:A, 6trd:a, 6trd:1, 5zf0:A1, 5zf0:A2, 5zf0:A3, 5zf0:A4, 5zf0:A6, 5zf0:A5
26 7f4v:aA 772 760 0.4577 0.4339 0.4408 0.0 7f4v:bA, 7f4v:cA
27 6k61:A 742 750 0.4440 0.4380 0.4333 0.0 6jeo:aA, 6jeo:bA, 6jeo:cA, 6jeo:dA, 6k61:a, 6tcl:A1, 6tcl:A2, 6tcl:A, 6tcl:AA, 7y3f:A
28 8wm6:A 742 753 0.4454 0.4394 0.4329 0.0 8wmj:A, 8wmv:A, 8wmw:A, 7y7b:A, 7y8a:A
29 5oy0:A 751 755 0.4522 0.4407 0.4384 0.0 8am5:a, 8asl:a, 8asp:a, 6hqb:A, 4kt0:A, 4l6v:A, 4l6v:a, 4l6v:1, 6nwa:A, 6nwa:a, 6nwa:H, 7o1v:A, 5oy0:a, 5oy0:1, 7umh:A, 7umh:H, 7umh:a, 6uzv:A, 6uzv:a, 6uzv:1, 6vpv:A, 6vpv:a, 6vpv:1
30 6igz:A 740 752 0.4481 0.4432 0.4362 0.0 6qph:A, 6rhz:A, 6sl5:A, 6yxr:A
31 7dr0:A 739 753 0.4481 0.4438 0.4356 0.0 7dr1:A, 7dr2:aA, 7dr2:bA, 7dr2:cA, 7dr2:dA
32 7qco:A 728 753 0.4508 0.4533 0.4382 0.0 7qco:E, 7qco:e, 7qco:a
33 7blz:A 743 753 0.4536 0.4468 0.4409 0.0 6fos:A, 8wey:A, 5zgb:A, 5zgh:A
34 6ly5:a 742 755 0.4426 0.4367 0.4291 0.0 6l4u:A
35 6kif:A 751 766 0.4536 0.4421 0.4334 0.0 6kif:G, 6kif:e, 6kig:A, 6kig:G, 6kig:e
36 7s3d:A 749 762 0.4440 0.4339 0.4265 0.0 7s3d:G, 7s3d:a
37 7dwq:A 726 753 0.4290 0.4325 0.4170 0.0
38 6kmw:aA 721 756 0.4426 0.4494 0.4286 0.0 6kmw:bA, 6kmw:cA
39 7lx0:G 751 748 0.4399 0.4288 0.4305 0.0 7lx0:a, 7lx0:A, 6pnj:A, 6pnj:G, 6pnj:a
40 7coy:aA 685 727 0.4139 0.4423 0.4168 0.0 7coy:bA, 7coy:cA
41 6kmx:aA 717 752 0.4249 0.4338 0.4136 1.64e-176 6kmx:bA, 6kmx:cA
42 8jze:b 663 736 0.4235 0.4676 0.4212 1.19e-175 8jzf:b
43 8jjr:b 659 747 0.4331 0.4810 0.4244 1.91e-175
44 8jw0:b 617 719 0.4098 0.4862 0.4172 2.74e-174
45 8jjr:a 665 742 0.3265 0.3594 0.3221 4.18e-104
46 8jw0:a 645 735 0.3292 0.3736 0.3279 2.05e-97
47 8jze:a 670 744 0.3005 0.3284 0.2957 1.35e-94 8jzf:a
48 7zq9:B2 180 219 0.2145 0.8722 0.7169 7.40e-93
49 7zq9:B2 180 27 0.0246 0.1000 0.6667 0.002
50 5v8k:A 600 236 0.0888 0.1083 0.2754 2.37e-10
51 6m32:A 628 80 0.0396 0.0462 0.3625 1.51e-05 6m32:a
52 8gwa:A 667 80 0.0396 0.0435 0.3625 1.81e-05 8gwa:a, 7uea:A, 7uea:a, 7ueb:A, 7ueb:a, 7z6q:A, 7z6q:a
53 7vzg:a 858 116 0.0369 0.0315 0.2328 0.023 7vzg:A, 7vzr:A, 7vzr:a

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218