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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ATKFPKFSQDLANDPTTRRIFYAIATAHDFESHDGMTEENLYQRIFASHFGHLAIIFLWASGILFHVAWQGNFEVWIKDP
VHVRPIAHAIWDAQFGPGAIKAFTQAGARNPVDICYSGVYHWWYTIGLRTNTELYVGALFLILLAAVFLFAGWLHLQPRY
RPNLGWFKNSEARLNHHLAGLFGVSSLAWAGHLVHVAIPESRGQHVGWDNFLSTPPHPAGLWAFFTGNWGAYAQNPDTAE
HVFSTSQGAGTAILTFLGGFHPQTQSLWLTDMAHHHLAIAVVLIIAGHMYRTNWRIGHSIKEMMDSKTFFGRKVEGPFNL
PHQGLYETVNNSLHFQLSLALACLGVASSLTAQHMYSMPPYAFIAKDFTTMAALYTHHQYIAGFLMVGAFSHAAIFWIKD
YDPEQNKGNVLERVLKHKEAIIAHLSWVSLFLGFHTLGLYVHNDVEVAFGAADKQILIEPVFAQFIQSANGKILYGFHTL
LSNPDSIAFTAWPNHANVWLPGWLDAINNGTNSLFLTIGPGDFYVHHAIALGLHVTTLILVKGALDARGSKLMPDKKDFG
YAFPCDGPGRGGTCDISAWDASYLAVFWMLNTLGWVTFYWHWKHLSIWQGNVAQFNESSTYLMGWFRDYLWANSAQLING
YNPYGTNNLAVWAWMFLFGHLAWAVSFMFLITWRGYWQELIETLAWAHEQTPLSFGYWRDKPVALSIVQARLVGLTHFTV
GYIATYGAFLIASTASKF

The query sequence (length=738) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7lx0:H 739 738 1.0000 0.9986 1.0000 0.0 7lx0:b, 7lx0:B, 6pnj:H, 6pnj:B, 6pnj:b
2 7fix:B1 740 739 0.8455 0.8432 0.8444 0.0 7bw2:B, 4fe1:B, 7fix:B2, 7fix:B3, 1jb0:B, 6k33:aB, 6k33:bB, 6k33:cB, 7m75:B, 7m76:B, 7m78:B, 3pcq:B, 6pfy:H, 6pfy:B, 6pfy:Z, 6pgk:H, 6pgk:B, 6pgk:Z, 6tra:B, 6trc:B, 6trc:b, 6trc:2, 6trd:B, 6trd:b, 6trd:2, 5zf0:B1, 5zf0:B2, 5zf0:B3, 5zf0:B4, 5zf0:B6, 5zf0:B5
3 6k61:B 740 739 0.8374 0.8351 0.8363 0.0 6jeo:aB, 6jeo:bB, 6jeo:cB, 6jeo:dB, 6k61:b, 6tcl:B1, 6tcl:B2, 6tcl:B, 6tcl:BB, 7y3f:B
4 7s3d:B 742 743 0.8347 0.8302 0.8291 0.0 7s3d:H, 7s3d:b
5 6kmx:aB 727 738 0.8198 0.8322 0.8198 0.0 6kmx:bB, 6kmx:cB
6 7qco:B 734 738 0.8144 0.8188 0.8144 0.0 7qco:G, 7qco:g, 7qco:b
7 6lu1:B 713 739 0.8184 0.8471 0.8173 0.0
8 6kmw:aB 740 740 0.8076 0.8054 0.8054 0.0 6kmw:cB, 6kmw:bB
9 6vpv:B 737 740 0.8035 0.8046 0.8014 0.0 8am5:b, 8asl:b, 8asp:b, 6hqb:B, 4kt0:B, 4l6v:B, 4l6v:b, 4l6v:2, 6nwa:B, 6nwa:b, 6nwa:G, 7o1v:B, 5oy0:B, 5oy0:b, 5oy0:2, 7umh:B, 7umh:G, 7umh:b, 6uzv:B, 6uzv:b, 6uzv:2, 6vpv:b, 6vpv:2
10 7y5e:BN 732 738 0.7710 0.7773 0.7710 0.0 7y5e:B2, 7y7a:B7, 7y7a:Bo, 7y7b:B, 7y8a:B
11 6kif:B 733 739 0.7873 0.7926 0.7862 0.0 6kif:H, 6kif:f, 6kig:B, 6kig:H, 6kig:f
12 7d0j:B 734 740 0.7683 0.7725 0.7662 0.0 7a4p:B, 7bgi:B, 7blx:B, 8cmo:B, 7dz7:B, 7dz8:B, 8h2u:B, 6ijj:B, 6ijo:B, 6jo5:B, 6jo6:B, 6qph:B, 7r3k:B, 6rhz:B, 6sl5:B, 7wyi:B, 7wzn:B, 6yxr:B, 7zq9:B, 7zqc:B, 7zqd:B, 7zqd:B2, 6zzx:B, 6zzy:B
13 7blz:B 731 739 0.7602 0.7674 0.7591 0.0 6fos:B, 8wey:B, 5zgb:B, 5zgh:B
14 8wm6:B 732 738 0.7493 0.7555 0.7493 0.0 8wmj:B, 8wmv:B, 8wmw:B
15 6igz:B 733 739 0.7615 0.7667 0.7605 0.0
16 7dr0:B 706 739 0.7642 0.7989 0.7632 0.0 7dr1:B, 7dr2:aB, 7dr2:bB, 7dr2:cB, 7dr2:dB
17 7yca:B 732 739 0.7575 0.7637 0.7564 0.0
18 6ly5:b 732 739 0.7371 0.7432 0.7361 0.0 6l4u:B
19 7wfd:AB 734 739 0.7480 0.7520 0.7470 0.0 8bcv:B, 8bcw:B, 7dkz:B, 7ew6:B, 7ewk:B, 7f9o:B, 7f9o:f, 8htu:B, 8j6z:B, 8j7a:B, 8j7b:B, 7ksq:B, 7kux:B, 6l35:B, 5l8r:B, 3lw5:B, 2o01:B, 4rku:B, 7wfe:BB, 7wg5:AB, 7wg5:BB, 8wgh:B, 2wsc:B, 2wse:B, 2wsf:B, 4xk8:B, 4xk8:b, 7xqp:B, 4y28:B, 6yac:B, 6yez:B, 5zji:B, 6zoo:B, 6zxs:B
20 7f4v:aB 725 740 0.6965 0.7090 0.6946 0.0 7f4v:bB, 7f4v:cB
21 7dwq:B 659 734 0.6531 0.7314 0.6567 0.0 7coy:aB, 7coy:bB, 7coy:cB
22 6k61:A 742 764 0.4444 0.4420 0.4293 0.0 6jeo:aA, 6jeo:bA, 6jeo:cA, 6jeo:dA, 6k61:a, 6tcl:A1, 6tcl:A2, 6tcl:A, 6tcl:AA, 7y3f:A
23 7f4v:aA 772 784 0.4526 0.4326 0.4260 0.0 7f4v:bA, 7f4v:cA
24 5l8r:A 743 760 0.4472 0.4441 0.4342 0.0 8bcv:A, 8bcw:A, 7dkz:A, 7ew6:A, 7ewk:A, 7f9o:A, 7f9o:e, 8htu:A, 8j6z:A, 8j7a:A, 8j7b:A, 7ksq:A, 7kux:A, 6l35:A, 3lw5:A, 2o01:A, 4rku:A, 7wfd:AA, 7wfe:BA, 7wg5:AA, 7wg5:BA, 8wgh:A, 2wsc:A, 2wse:A, 2wsf:A, 4xk8:A, 4xk8:a, 7xqp:A, 4y28:A, 6yac:A, 6yez:A, 5zji:A, 6zoo:A, 6zxs:A
25 6tra:A 746 768 0.4444 0.4397 0.4271 0.0 4fe1:A, 7fix:A1, 7fix:A2, 7fix:A3, 1jb0:A, 6k33:aA, 6k33:bA, 6k33:cA, 6lu1:A, 7m75:A, 7m76:A, 7m78:A, 3pcq:A, 6pfy:A, 6pfy:G, 6pfy:Y, 6pgk:A, 6pgk:G, 6pgk:Y, 6trc:A, 6trc:a, 6trc:1, 6trd:A, 6trd:a, 6trd:1, 5zf0:A1, 5zf0:A2, 5zf0:A3, 5zf0:A4, 5zf0:A6, 5zf0:A5
26 7dr0:A 739 764 0.4404 0.4398 0.4254 0.0 7dr1:A, 7dr2:aA, 7dr2:bA, 7dr2:cA, 7dr2:dA
27 6kif:A 751 772 0.4472 0.4394 0.4275 0.0 6kif:G, 6kif:e, 6kig:A, 6kig:G, 6kig:e
28 7yca:A 742 759 0.4309 0.4286 0.4190 0.0 7a4p:A, 7bgi:A, 7blx:A, 8cmo:A, 7d0j:A, 7dz7:A, 7dz8:A, 8h2u:A, 6ijj:A, 6ijo:A, 6jo5:A, 6jo6:A, 7r3k:A, 7wyi:A, 7wzn:A, 7zq9:A, 7zqc:A, 7zqd:A, 7zqd:A2, 6zzx:A, 6zzy:A
29 6igz:A 740 759 0.4363 0.4351 0.4242 0.0 6qph:A, 6rhz:A, 6sl5:A, 6yxr:A
30 7y5e:AN 745 763 0.4282 0.4242 0.4142 0.0 7y5e:A2, 7y7a:A7, 7y7a:Ao
31 7s3d:A 749 769 0.4377 0.4312 0.4200 0.0 7s3d:G, 7s3d:a
32 5oy0:A 751 767 0.4377 0.4301 0.4211 0.0 8am5:a, 8asl:a, 8asp:a, 6hqb:A, 4kt0:A, 4l6v:A, 4l6v:a, 4l6v:1, 6nwa:A, 6nwa:a, 6nwa:H, 7o1v:A, 5oy0:a, 5oy0:1, 7umh:A, 7umh:H, 7umh:a, 6uzv:A, 6uzv:a, 6uzv:1, 6vpv:A, 6vpv:a, 6vpv:1
33 7qco:A 728 764 0.4390 0.4451 0.4241 0.0 7qco:E, 7qco:e, 7qco:a
34 8wm6:A 742 779 0.4295 0.4272 0.4069 0.0 8wmj:A, 8wmv:A, 8wmw:A, 7y7b:A, 7y8a:A
35 7blz:A 743 762 0.4363 0.4334 0.4226 1.94e-180 6fos:A, 8wey:A, 5zgb:A, 5zgh:A
36 7dwq:A 726 767 0.4214 0.4284 0.4055 3.01e-180
37 7lx0:G 751 780 0.4431 0.4354 0.4192 4.88e-179 7lx0:a, 7lx0:A, 6pnj:A, 6pnj:G, 6pnj:a
38 8jjr:b 659 747 0.4214 0.4719 0.4163 4.58e-177
39 6kmw:aA 721 763 0.4322 0.4424 0.4181 6.63e-175 6kmw:bA, 6kmw:cA
40 8jze:b 663 746 0.4038 0.4495 0.3995 5.25e-174 8jzf:b
41 7coy:aA 685 735 0.4024 0.4336 0.4041 1.23e-173 7coy:bA, 7coy:cA
42 6ly5:a 742 764 0.4133 0.4111 0.3992 2.26e-173 6l4u:A
43 6kmx:aA 717 758 0.4201 0.4324 0.4090 2.73e-171 6kmx:bA, 6kmx:cA
44 8jw0:b 617 726 0.3943 0.4716 0.4008 1.73e-165
45 8jjr:a 665 726 0.2995 0.3323 0.3044 6.01e-100
46 8jw0:a 645 741 0.3103 0.3550 0.3090 2.63e-93
47 8jze:a 670 727 0.2791 0.3075 0.2834 3.72e-90 8jzf:a
48 7zq9:B2 180 214 0.1694 0.6944 0.5841 5.59e-70
49 5v8k:A 600 366 0.1355 0.1667 0.2732 5.97e-14
50 6m32:A 628 80 0.0393 0.0462 0.3625 5.35e-05 6m32:a
51 8gwa:A 667 80 0.0393 0.0435 0.3625 6.27e-05 8gwa:a, 7uea:A, 7uea:a, 7ueb:A, 7ueb:a, 7z6q:A, 7z6q:a
52 7vzg:a 858 115 0.0447 0.0385 0.2870 6.05e-04 7vzg:A, 7vzr:A, 7vzr:a
53 1y1p:A 342 121 0.0501 0.1082 0.3058 0.38 1y1p:B
54 2xvz:A 263 48 0.0230 0.0646 0.3542 8.3 2xvx:A, 2xvy:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218