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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ATFVRNAWYVAALPEELSEKPLGRTILDTPLALYRQPDGVVAALLDICPHRFAPLSDGILVNGHLQCPYHGLEFDGGGQC
VHNPHGNGARPASLNVRSFPVVERDALIWIWPGDPALADPGAIPDFGCRVDPAYRTVGGYGHVDCNYKLLVDNLMDLEVI
VGDGEIQALMKIPGGTPSVLMAKFLRGANTPVDAWNDIRWNKVSAMLNFIAVAPEGTPKEQSIHSRGTHILTPETEASCH
YFFGSSRNFGIDDPEMDGVLRSWQAQALVKEDKVVVEAIERRRAYVEANGIRPAMLSCDEAAVRVSREIEKLEQLEAARL

The query sequence (length=320) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6vsh:C 320 320 1.0000 1.0000 1.0000 0.0 3gke:C, 3gl0:C, 3gl2:C
2 3gob:A 342 341 1.0000 0.9357 0.9384 0.0 3gb4:A, 3gb4:B, 3gb4:C, 3gke:A, 3gke:B, 3gl0:A, 3gl0:B, 3gl2:A, 3gl2:B, 3gob:B, 3gob:C, 3gte:A, 3gte:B, 3gte:C, 3gts:A, 3gts:B, 3gts:C, 6vsh:A, 6vsh:B
3 7qwt:A 352 333 0.3312 0.3011 0.3183 6.84e-51 7qwt:B, 7qwt:C, 7qwt:D, 7qwt:E, 7qwt:F, 7qwt:G, 7qwt:H, 7qwt:I
4 7sze:B 329 134 0.1437 0.1398 0.3433 3.80e-15 7sze:A, 7sze:C, 7szf:A, 7szf:B, 7szf:C, 7szg:A, 7szg:B, 7szg:C, 6wnc:A, 6wnc:B, 6wnc:C, 6wnd:A, 6wnd:B, 6wnd:C
5 6wn3:B 328 134 0.1406 0.1372 0.3358 2.33e-14 7szh:A, 7szh:B, 7szh:C, 6wn3:A, 6wn3:C, 6wnb:A, 6wnb:B, 6wnb:C
6 6icn:A 344 142 0.1531 0.1424 0.3451 6.55e-11 6ick:A, 6ick:B, 6ick:C, 6icm:A, 6icm:B, 6icm:C, 6icn:B, 6icn:C, 6ico:A, 6ico:B, 6ico:C, 6icp:A, 6icp:B, 6icp:C, 6icq:A, 6icq:B, 6icq:C
7 7fhr:A 437 139 0.1219 0.0892 0.2806 1.12e-10
8 4qdf:B 357 161 0.1250 0.1120 0.2484 3.05e-09
9 3gkq:A 374 161 0.1500 0.1283 0.2981 8.53e-07 3gkq:B, 3gkq:C, 3gkq:D, 3gkq:E, 3gkq:F
10 6icl:A 338 89 0.0938 0.0888 0.3371 9.11e-07
11 2zyl:A 359 121 0.1000 0.0891 0.2645 2.01e-06 4qck:A
12 7v28:B 425 163 0.1281 0.0965 0.2515 3.06e-06 7fjl:A, 7fjl:B, 7fjl:C, 7fjl:D, 7fjl:E, 7fjl:F, 7v25:B, 7v25:A, 7v25:C, 7v25:D, 7v25:E, 7v25:F, 7v28:A, 7v28:C, 7v28:D, 7v28:E, 7v28:F
13 2qpz:A 103 93 0.0938 0.2913 0.3226 3.90e-06
14 4qdc:A 369 172 0.1313 0.1138 0.2442 3.91e-06 4qdd:A, 4qdf:A
15 5bok:A 102 98 0.0906 0.2843 0.2959 1.56e-04
16 4nbb:E 114 81 0.0781 0.2193 0.3086 1.81e-04 7buh:A, 7bui:D, 7bui:E, 2de5:D, 2de5:E, 2de5:F, 2de6:D, 2de6:E, 2de6:F, 2de7:D, 2de7:E, 2de7:F, 6llf:D, 6llf:E, 6llf:F, 6llh:D, 6llh:E, 6llh:F, 4nb8:D, 4nb8:E, 4nb8:F, 4nb9:D, 4nb9:E, 4nb9:F, 4nba:D, 4nba:E, 4nba:F, 4nbb:D, 4nbb:F, 4nbc:D, 4nbc:E, 4nbc:F, 4nbd:D, 4nbd:E, 4nbe:D, 4nbe:E, 4nbf:D, 4nbf:E, 4nbf:F, 4nbg:D, 4nbg:E, 4nbg:F, 4nbh:D, 4nbh:E, 4nbh:F, 1vck:A, 3vmg:D, 3vmg:E, 3vmg:F, 3vmh:D, 3vmh:E, 3vmh:F, 3vmi:D, 3vmi:E, 3vmi:F
17 3gcf:A 367 157 0.1313 0.1144 0.2675 2.11e-04 3gcf:B, 3gcf:C, 3gcf:D, 3gcf:E, 3gcf:F, 3gcf:G, 3gcf:H, 3gcf:I, 3gcf:J, 3gcf:K, 3gcf:L, 3gcf:M, 3gcf:N, 3gcf:O
18 6y9c:A 365 163 0.1187 0.1041 0.2331 4.33e-04 6y8s:A, 6y9d:A, 6y9d:B, 6y9d:C, 6y9d:D, 6y9d:E, 6y9d:F, 6y9d:G, 6y9d:H, 6y9d:I, 6y9d:J, 6y9d:K, 6y9d:L, 6zgp:A, 6zgp:B, 6zgp:C, 6zgp:D, 6zgp:E, 6zgp:F, 6zgp:G, 6zgp:H, 6zgp:I, 6zgp:J, 6zgp:K, 6zgp:L
19 6y8j:A 343 163 0.1187 0.1108 0.2331 5.30e-04
20 7yls:B 436 98 0.0875 0.0642 0.2857 8.89e-04 8h2t:B, 8h2t:D, 8h2t:G
21 2b1x:A 441 168 0.1375 0.0998 0.2619 0.001 2b1x:C, 2b1x:E, 2b24:A, 2b24:C, 2b24:E
22 2i7f:A 102 90 0.0750 0.2353 0.2667 0.003 2i7f:B
23 3en1:A 424 59 0.0563 0.0425 0.3051 0.009 3eqq:A
24 1uli:C 425 66 0.0625 0.0471 0.3030 0.021 1uli:A, 1uli:E, 1ulj:A, 1ulj:C, 1ulj:E
25 2bmo:A 437 75 0.0688 0.0503 0.2933 0.022 2bmq:A, 2bmr:A
26 8jng:A 147 82 0.0844 0.1837 0.3293 0.027
27 1wql:A 436 59 0.0531 0.0390 0.2881 0.035
28 1eg9:A 447 70 0.0688 0.0492 0.3143 0.058 4hjl:A, 4hkv:A, 2hmj:A, 2hmk:A, 2hml:A, 2hmm:A, 2hmn:A, 2hmo:A, 4hm0:A, 4hm1:A, 4hm2:A, 4hm3:A, 4hm4:A, 4hm5:A, 4hm6:A, 4hm7:A, 4hm8:A, 1ndo:A, 1ndo:C, 1ndo:E, 1o7g:A, 1o7h:A, 1o7m:A, 1o7n:A, 1o7p:A, 1o7w:A, 1uuv:A, 1uuw:A
29 2gbw:A 449 180 0.1375 0.0980 0.2444 0.066 2ckf:A, 2gbw:C, 2gbw:E, 2gbx:A, 2gbx:C, 2gbx:E
30 5xbp:A 444 75 0.0656 0.0473 0.2800 0.070 5xbp:D, 5xbp:G
31 5aeu:A 433 64 0.0563 0.0416 0.2812 0.12 5aeu:C, 5aeu:E, 5aeu:G, 5aew:A, 5aew:C, 5aew:E, 5aew:G, 5aew:I, 5aew:K, 5aew:M, 5aew:O, 5aew:Q, 5aew:S, 5aew:U, 5aew:W, 2xr8:A, 2xr8:C, 2xr8:E, 2xr8:G, 2xr8:I, 2xr8:K, 2xr8:M, 2xr8:O, 2xr8:Q, 2xr8:S, 2xr8:U, 2xr8:W, 2xrx:A, 2xrx:C, 2xrx:E, 2xrx:G, 2xrx:I, 2xrx:K, 2xrx:M, 2xrx:O, 2xrx:Q, 2xrx:S, 2xrx:U, 2xrx:W, 2xsh:A, 2xsh:C, 2xsh:E, 2xsh:G, 2xsh:I, 2xsh:K, 2xso:A, 2xso:C, 2xso:E, 2xso:G, 2xso:I, 2xso:K, 2xso:M, 2xso:O, 2xso:Q, 2xso:S, 2xso:U, 2xso:W, 2yfi:A, 2yfi:C, 2yfi:E, 2yfi:G, 2yfi:I, 2yfi:K, 2yfj:A, 2yfj:C, 2yfj:E, 2yfj:G, 2yfj:I, 2yfj:K, 2yfl:A, 2yfl:C, 2yfl:E, 2yfl:G, 2yfl:I, 2yfl:K
32 8c3a:D 214 82 0.0531 0.0794 0.2073 0.16 8c3a:CO, 8cq7:D, 8cq7:CO, 8cqw:D, 8cqw:CO, 8cre:D, 8cre:CO, 8oeq:D, 8oeq:CO, 7pzy:C, 7q08:C, 7q0f:C, 7q0p:C, 7q0r:C, 8q5i:C
33 3gzx:A 440 59 0.0594 0.0432 0.3220 0.21 3gzy:A
34 7d4i:SC 242 82 0.0469 0.0620 0.1829 0.31 7a1g:Q, 7ajt:DA, 7aju:DA, 7b7d:Q, 8bn3:S1, 8bqd:Q, 8bqx:Q, 8c00:Q, 8c01:Q, 8cah:Q, 8cas:Q, 8cbj:B, 8ccs:e, 8cdl:e, 8cdr:e, 8ceh:e, 8cf5:e, 8cg8:e, 8cgn:e, 8civ:e, 8cku:e, 8cmj:e, 7d5t:SC, 7d63:SC, 5dat:S1, 5dat:s1, 5dc3:S1, 5dc3:s1, 5dge:S1, 5dge:s1, 5dgf:S1, 5dgf:s1, 5dgv:S1, 5dgv:s1, 6eml:Q, 8eub:BB, 8evp:BB, 8evq:BB, 8evr:BB, 8evs:BB, 8evt:BB, 8ewb:BB, 8ewc:BB, 6fai:B, 5fci:S1, 5fci:s1, 5fcj:S1, 5fcj:s1, 6fyx:B, 6fyy:B, 6gq1:r, 6gqb:r, 6gqv:r, 6gsm:B, 6gsn:B, 6hhq:s1, 6hhq:C, 5i4l:S1, 5i4l:s1, 6i7o:Q, 6i7o:Qb, 8i7j:B, 5it7:B, 5it9:B, 3j6x:S1, 3j6y:S1, 3j77:S1, 3j78:S1, 3j80:B, 3j81:B, 3jam:B, 3jap:B, 5juo:YA, 5jup:YA, 5jus:YA, 5jut:YA, 5juu:YA, 8k2d:SB, 8k82:SB, 6ke6:SC, 5ll6:Q, 6lqp:SC, 6lqq:SC, 6lqr:SC, 6lqs:SC, 6lqt:SC, 5lyb:S1, 5lyb:s1, 5m1j:B2, 5mc6:Q, 5mei:s1, 5mei:C, 7mpi:BB, 7mpj:BB, 7n8b:BB, 5ndg:S1, 5ndg:s1, 5ndv:S1, 5ndv:s1, 5ndw:S1, 5ndw:s1, 7nrc:SQ, 7nrd:SQ, 5obm:S1, 5obm:s1, 5on6:s1, 5on6:C, 7osa:eS1, 7osm:eS1, 6q8y:Q, 6rbd:B, 6rbe:B, 7rr5:SB, 8rw1:B, 6s47:BC, 8s8d:B, 8s8e:B, 8s8f:B, 8s8g:B, 8s8h:B, 8s8i:B, 8s8j:B, 6snt:B, 6sv4:Q, 6sv4:Qb, 6sv4:Qc, 6t4q:SB, 6t7i:SB, 6t7t:SB, 6t83:Ba, 6t83:c, 5tbw:s1, 5tbw:C, 6tb3:Q, 5tga:S1, 5tga:s1, 5tgm:S1, 5tgm:s1, 6tnu:Q, 4u3m:S1, 4u3m:s1, 4u3n:S1, 4u3n:s1, 4u3u:S1, 4u3u:s1, 4u4n:S1, 4u4n:s1, 4u4o:S1, 4u4o:s1, 4u4q:S1, 4u4q:s1, 4u4r:S1, 4u4r:s1, 4u4u:S1, 4u4u:s1, 4u4y:S1, 4u4y:s1, 4u4z:S1, 4u4z:s1, 4u50:S1, 4u50:s1, 4u51:S1, 4u51:s1, 4u52:S1, 4u52:s1, 4u53:S1, 4u53:s1, 4u55:S1, 4u55:s1, 4u56:S1, 4u56:s1, 4u6f:S1, 4u6f:s1, 4uer:4, 6uz7:B, 4v88:AB, 4v88:CB, 4v8y:AB, 4v8z:AB, 4v92:BB, 6woo:BB, 7wtl:SB, 7wtm:SB, 7wtn:SB, 7wto:SB, 7wtp:SB, 7wtq:SB, 7wtr:SB, 5wyj:SC, 5wyk:SC, 6xiq:r, 6xir:r, 8y0u:SB, 6y7c:B, 6z6j:SB, 6z6k:SB, 6zce:C, 7zpq:AB, 6zqa:DA, 6zqb:DA, 6zqc:DA, 6zqd:DA, 6zqe:DA, 6zqf:DA, 6zqg:DA, 7zrs:AB, 6zu9:Q, 7zuw:AB, 7zux:DB, 6zvi:j, 7zw0:sQ
35 4aay:B 132 47 0.0625 0.1515 0.4255 0.40 4aay:D, 4aay:F, 4aay:H, 8ccq:B, 8ccq:D, 8ccq:F, 8ccq:H, 8ed4:B, 8ed4:D, 8ed4:F, 8ed4:H, 5nqd:B, 5nqd:D, 5nqd:F, 5nqd:H
36 1sjg:A 112 82 0.0625 0.1786 0.2439 1.8 4p1b:H, 4p1b:I, 4p1c:H, 4p1c:I, 2q3w:A, 1vm9:A
37 7c8z:A 383 91 0.0688 0.0574 0.2418 2.4 7c8z:C, 7c8z:E, 7c8z:G
38 5dok:A 170 46 0.0500 0.0941 0.3478 2.5 5dok:B
39 3chv:A 279 130 0.0906 0.1039 0.2231 2.7
40 6sl5:5 202 48 0.0563 0.0891 0.3750 3.2
41 7q05:E 409 95 0.0750 0.0587 0.2526 3.4 7q04:D, 7q04:E, 7q04:F, 7q05:D, 7q05:F, 7q06:D, 7q06:E, 7q06:F, 7vju:A, 7vju:C, 7vju:E
42 3azc:A 133 43 0.0469 0.1128 0.3488 4.1
43 8cas:G 396 76 0.0594 0.0480 0.2500 4.2 6fyy:k, 6i3m:O, 6i3m:P, 6i7t:O, 6i7t:P, 3jap:k, 8s8f:k
44 3dqy:A 106 69 0.0750 0.2264 0.3478 4.7 4emj:B
45 6hiv:AJ 126 41 0.0437 0.1111 0.3415 5.4 6hix:AJ
46 7olc:SB 232 84 0.0531 0.0733 0.2024 6.0 7old:SB, 8oo0:SB, 5oql:l, 7r81:C2, 6rxt:Ca, 6rxu:Ca, 6rxv:Ca, 6rxx:Ca, 7z3n:SB, 7z3o:SB
47 5cxm:A 99 23 0.0312 0.1010 0.4348 6.9 5cxm:B, 5cxm:C, 5cxm:D
48 2a06:E 196 79 0.0656 0.1071 0.2658 7.8 2a06:R, 1bcc:E, 2bcc:E, 3bcc:E, 1be3:E, 1bgy:Q, 4d6t:R, 4d6u:R, 7dkf:Q1, 2fyu:E, 5gpn:E, 5gpn:Q, 5gup:2, 5gup:4, 6haw:E, 8iog:C, 8iog:c, 5j4z:AE, 5j4z:AP, 5j7y:AE, 5j7y:AP, 5j8k:AE, 5j8k:AP, 5klv:E, 1l0l:E, 1l0n:E, 5luf:q, 6nhg:E, 5nmi:E, 1ntk:E, 1ntm:E, 1ntz:E, 1nu1:E, 7o37:E, 7o37:P, 7o3c:E, 7o3c:P, 7o3h:E, 7o3h:P, 5okd:E, 8p65:E, 8p65:R, 1pp9:R, 1pp9:E, 1ppj:R, 1ppj:E, 8pw5:E, 8pw5:P, 8pw6:E, 8pw6:P, 8pw7:E, 8pw7:P, 6q9e:f1, 6q9e:f2, 6qbx:f1, 6qbx:f2, 6qc2:f1, 6qc2:f2, 6qc3:f1, 6qc3:f2, 6qc4:f1, 6qc4:f2, 7r3v:E, 1rie:A, 1sqb:E, 1sqp:E, 1sqq:E, 1sqv:E, 1sqx:E, 7tay:E, 7tz6:E, 7tz6:R, 8ugd:3E, 8ugd:3R, 8uge:3E, 8uge:3R, 8ugf:3E, 8ugf:3R, 8ugg:3E, 8ugg:3R, 8ugh:3E, 8ugh:3R, 8ugi:3E, 8ugi:3R, 8ugj:3E, 8ugj:3R, 8ugk:3E, 8ugk:3R, 8ugn:3E, 8ugn:3R, 8ugr:3E, 8ugr:3R, 8ugr:6E, 8ugr:6R, 5xte:C, 5xte:P, 5xth:AC, 5xth:AP, 5xti:AC, 5xti:AP, 6xvf:E, 2ybb:e, 2ybb:E, 6zfs:E, 6zft:E, 6zfu:E
49 7ase:f 1523 38 0.0437 0.0092 0.3684 9.0 7ask:F
50 6o1e:A 431 61 0.0531 0.0394 0.2787 9.7 5ix1:B, 5ix2:A, 5ix2:B, 4qq4:A, 4qq4:B, 5svi:A, 5svi:B, 5svx:A, 5svy:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218