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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ASRFPKFSRGLSQDPTTRRIWFGIATAHDFESHDDMTEERLYQKIFASHFGQLAIIFLWTSGNLFHVAWQGNFEAWGQDP
LHVRPIAHAIWDPHFGQPAVEAFTRGGASGPVNIAYSGVYQWWYTIGLRTNQDLYGGSIFLLFVSALFLIAGWLHLQPKW
KPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPESRGEHVRWNNLLTALPHPQGLGPFFAGQWNVYAQNPDSNS
HLFGTSEGAGTAILTFLGGFHPQTQSLWLTDMAHHHLAIAVIFIIAGHMYRTNFGIGHSMKEILEAHTPPGGRLGRGHKG
LYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPPYAFLAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPE
QNKDNVLARMLEHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPVFAQWIQSAHGKALYGFDVLLSSA
DSPAFNAGQTLWLPGWLDAINNNSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKEFGYSFPCDG
PGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVAQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMN
SLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLVRWKDKPVALSIVQARLVGLAHFSVGYIFTY
AAFLIASTSGKFG

The query sequence (length=733) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7wfd:AB 734 733 0.9250 0.9237 0.9250 0.0 8bcv:B, 8bcw:B, 7dkz:B, 7ew6:B, 7ewk:B, 7f9o:B, 7f9o:f, 8htu:B, 8j6z:B, 8j7a:B, 8j7b:B, 7ksq:B, 7kux:B, 6l35:B, 5l8r:B, 3lw5:B, 2o01:B, 4rku:B, 7wfe:BB, 7wg5:AB, 7wg5:BB, 8wgh:B, 2wsc:B, 2wse:B, 2wsf:B, 4xk8:B, 4xk8:b, 7xqp:B, 4y28:B, 6yac:B, 6yez:B, 5zji:B, 6zoo:B, 6zxs:B
2 7d0j:B 734 730 0.8786 0.8774 0.8822 0.0 7a4p:B, 7bgi:B, 7blx:B, 8cmo:B, 7dz7:B, 7dz8:B, 8h2u:B, 6ijj:B, 6ijo:B, 6jo5:B, 6jo6:B, 6qph:B, 7r3k:B, 6rhz:B, 6sl5:B, 7wyi:B, 7wzn:B, 6yxr:B, 7zq9:B, 7zqc:B, 7zqd:B, 7zqd:B2, 6zzx:B, 6zzy:B
3 6igz:B 733 733 0.8772 0.8772 0.8772 0.0
4 7yca:B 732 733 0.8649 0.8661 0.8649 0.0
5 7y5e:BN 732 732 0.8499 0.8511 0.8511 0.0 7y5e:B2, 7y7a:B7, 7y7a:Bo, 7y7b:B, 7y8a:B
6 6vpv:B 737 738 0.8431 0.8385 0.8374 0.0 8am5:b, 8asl:b, 8asp:b, 6hqb:B, 4kt0:B, 4l6v:B, 4l6v:b, 4l6v:2, 6nwa:B, 6nwa:b, 6nwa:G, 7o1v:B, 5oy0:B, 5oy0:b, 5oy0:2, 7umh:B, 7umh:G, 7umh:b, 6uzv:B, 6uzv:b, 6uzv:2, 6vpv:b, 6vpv:2
7 6kif:B 733 733 0.8404 0.8404 0.8404 0.0 6kif:H, 6kif:f, 6kig:B, 6kig:H, 6kig:f
8 8wm6:B 732 732 0.8158 0.8169 0.8169 0.0 8wmj:B, 8wmv:B, 8wmw:B
9 7blz:B 731 732 0.8213 0.8235 0.8224 0.0 6fos:B, 8wey:B, 5zgb:B, 5zgh:B
10 6kmw:aB 740 740 0.8295 0.8216 0.8216 0.0 6kmw:cB, 6kmw:bB
11 6ly5:b 732 733 0.8104 0.8115 0.8104 0.0 6l4u:B
12 7fix:B1 740 740 0.8240 0.8162 0.8162 0.0 7bw2:B, 4fe1:B, 7fix:B2, 7fix:B3, 1jb0:B, 6k33:aB, 6k33:bB, 6k33:cB, 7m75:B, 7m76:B, 7m78:B, 3pcq:B, 6pfy:H, 6pfy:B, 6pfy:Z, 6pgk:H, 6pgk:B, 6pgk:Z, 6tra:B, 6trc:B, 6trc:b, 6trc:2, 6trd:B, 6trd:b, 6trd:2, 5zf0:B1, 5zf0:B2, 5zf0:B3, 5zf0:B4, 5zf0:B6, 5zf0:B5
13 7qco:B 734 735 0.8076 0.8065 0.8054 0.0 7qco:G, 7qco:g, 7qco:b
14 6k61:B 740 740 0.8035 0.7959 0.7959 0.0 6jeo:aB, 6jeo:bB, 6jeo:cB, 6jeo:dB, 6k61:b, 6tcl:B1, 6tcl:B2, 6tcl:B, 6tcl:BB, 7y3f:B
15 7dr0:B 706 734 0.8035 0.8343 0.8025 0.0 7dr1:B, 7dr2:aB, 7dr2:bB, 7dr2:cB, 7dr2:dB
16 6lu1:B 713 735 0.8063 0.8289 0.8041 0.0
17 7s3d:B 742 742 0.7722 0.7628 0.7628 0.0 7s3d:H, 7s3d:b
18 7lx0:H 739 740 0.7708 0.7645 0.7635 0.0 7lx0:b, 7lx0:B, 6pnj:H, 6pnj:B, 6pnj:b
19 6kmx:aB 727 735 0.7694 0.7758 0.7673 0.0 6kmx:bB, 6kmx:cB
20 7f4v:aB 725 732 0.7462 0.7545 0.7473 0.0 7f4v:bB, 7f4v:cB
21 7dwq:B 659 727 0.6849 0.7618 0.6905 0.0 7coy:aB, 7coy:bB, 7coy:cB
22 7f4v:aA 772 766 0.4707 0.4469 0.4504 0.0 7f4v:bA, 7f4v:cA
23 7y5e:AN 745 753 0.4598 0.4523 0.4475 0.0 7y5e:A2, 7y7a:A7, 7y7a:Ao
24 6k61:A 742 751 0.4584 0.4528 0.4474 0.0 6jeo:aA, 6jeo:bA, 6jeo:cA, 6jeo:dA, 6k61:a, 6tcl:A1, 6tcl:A2, 6tcl:A, 6tcl:AA, 7y3f:A
25 5l8r:A 743 754 0.4679 0.4616 0.4549 0.0 8bcv:A, 8bcw:A, 7dkz:A, 7ew6:A, 7ewk:A, 7f9o:A, 7f9o:e, 8htu:A, 8j6z:A, 8j7a:A, 8j7b:A, 7ksq:A, 7kux:A, 6l35:A, 3lw5:A, 2o01:A, 4rku:A, 7wfd:AA, 7wfe:BA, 7wg5:AA, 7wg5:BA, 8wgh:A, 2wsc:A, 2wse:A, 2wsf:A, 4xk8:A, 4xk8:a, 7xqp:A, 4y28:A, 6yac:A, 6yez:A, 5zji:A, 6zoo:A, 6zxs:A
26 6tra:A 746 743 0.4543 0.4464 0.4482 0.0 4fe1:A, 7fix:A1, 7fix:A2, 7fix:A3, 1jb0:A, 6k33:aA, 6k33:bA, 6k33:cA, 6lu1:A, 7m75:A, 7m76:A, 7m78:A, 3pcq:A, 6pfy:A, 6pfy:G, 6pfy:Y, 6pgk:A, 6pgk:G, 6pgk:Y, 6trc:A, 6trc:a, 6trc:1, 6trd:A, 6trd:a, 6trd:1, 5zf0:A1, 5zf0:A2, 5zf0:A3, 5zf0:A4, 5zf0:A6, 5zf0:A5
27 7yca:A 742 752 0.4502 0.4447 0.4388 0.0 7a4p:A, 7bgi:A, 7blx:A, 8cmo:A, 7d0j:A, 7dz7:A, 7dz8:A, 8h2u:A, 6ijj:A, 6ijo:A, 6jo5:A, 6jo6:A, 7r3k:A, 7wyi:A, 7wzn:A, 7zq9:A, 7zqc:A, 7zqd:A, 7zqd:A2, 6zzx:A, 6zzy:A
28 5oy0:A 751 760 0.4638 0.4527 0.4474 0.0 8am5:a, 8asl:a, 8asp:a, 6hqb:A, 4kt0:A, 4l6v:A, 4l6v:a, 4l6v:1, 6nwa:A, 6nwa:a, 6nwa:H, 7o1v:A, 5oy0:a, 5oy0:1, 7umh:A, 7umh:H, 7umh:a, 6uzv:A, 6uzv:a, 6uzv:1, 6vpv:A, 6vpv:a, 6vpv:1
29 8wm6:A 742 753 0.4516 0.4461 0.4396 0.0 8wmj:A, 8wmv:A, 8wmw:A, 7y7b:A, 7y8a:A
30 7blz:A 743 753 0.4598 0.4536 0.4475 0.0 6fos:A, 8wey:A, 5zgb:A, 5zgh:A
31 6kif:A 751 765 0.4611 0.4501 0.4418 0.0 6kif:G, 6kif:e, 6kig:A, 6kig:G, 6kig:e
32 7dr0:A 739 751 0.4488 0.4452 0.4381 0.0 7dr1:A, 7dr2:aA, 7dr2:bA, 7dr2:cA, 7dr2:dA
33 6ly5:a 742 755 0.4502 0.4447 0.4371 0.0 6l4u:A
34 6igz:A 740 752 0.4475 0.4432 0.4362 0.0 6qph:A, 6rhz:A, 6sl5:A, 6yxr:A
35 6kmw:aA 721 756 0.4529 0.4605 0.4392 0.0 6kmw:bA, 6kmw:cA
36 7qco:A 728 753 0.4529 0.4560 0.4409 0.0 7qco:E, 7qco:e, 7qco:a
37 7dwq:A 726 762 0.4379 0.4421 0.4213 0.0
38 7s3d:A 749 763 0.4393 0.4299 0.4220 0.0 7s3d:G, 7s3d:a
39 7coy:aA 685 730 0.4284 0.4584 0.4301 0.0 7coy:bA, 7coy:cA
40 7lx0:G 751 767 0.4543 0.4434 0.4342 0.0 7lx0:a, 7lx0:A, 6pnj:A, 6pnj:G, 6pnj:a
41 8jjr:b 659 740 0.4407 0.4901 0.4365 2.93e-180
42 8jze:b 663 734 0.4270 0.4721 0.4264 1.59e-178 8jzf:b
43 6kmx:aA 717 752 0.4243 0.4338 0.4136 1.20e-177 6kmx:bA, 6kmx:cA
44 8jw0:b 617 719 0.4106 0.4878 0.4186 1.44e-177
45 8jjr:a 665 744 0.3247 0.3579 0.3199 1.27e-103
46 8jze:a 670 741 0.3083 0.3373 0.3050 1.91e-96 8jzf:a
47 8jw0:a 645 734 0.3206 0.3643 0.3202 3.23e-92
48 7zq9:B2 180 216 0.1869 0.7611 0.6343 1.44e-79
49 7zq9:B2 180 27 0.0218 0.0889 0.5926 0.041
50 5v8k:A 600 234 0.0900 0.1100 0.2821 7.15e-13
51 6m32:A 628 80 0.0396 0.0462 0.3625 1.12e-05 6m32:a
52 8gwa:A 667 80 0.0396 0.0435 0.3625 1.26e-05 8gwa:a, 7uea:A, 7uea:a, 7ueb:A, 7ueb:a, 7z6q:A, 7z6q:a
53 7vzg:a 858 116 0.0409 0.0350 0.2586 0.001 7vzg:A, 7vzr:A, 7vzr:a
54 4is3:C 250 104 0.0341 0.1000 0.2404 5.3 4is3:A, 4is3:B, 4is3:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218