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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ASPAKRIQAFTGDPDFMTSLARGLAVIQAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTDGRTYSLLPKVL
TLGHAYLSSTPLAISAQPYLDRISDQLHEAANMATLEGDDILYIARSALSVGGRLPAYCTSMGRILLAAMDDTSLREYLE
RADLKARTSRTLNDPESLFACIQQVRAQGWCVVDQELEQGLRSIAVPVYDASGQVLAALNVSTHVGRVTRSELEQRFLPI
LLAASRDLCHQLFG

The query sequence (length=254) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8eju:B 257 251 0.9528 0.9416 0.9641 3.45e-176 8eju:A
2 5hpf:A 175 165 0.2008 0.2914 0.3091 5.42e-20 5hpf:C, 5hpi:A, 5hpi:B, 5hpi:C, 5hpi:D
3 5whm:A 263 248 0.2756 0.2662 0.2823 3.32e-16
4 2o99:C 182 174 0.1811 0.2527 0.2644 6.42e-15 2o99:A, 2o99:B, 2o99:D, 2o9a:A, 2o9a:B, 2o9a:C, 2o9a:D
5 1mkm:A 246 245 0.1890 0.1951 0.1959 2.12e-14
6 2xro:B 240 196 0.2087 0.2208 0.2704 1.97e-09 2xro:A, 2xro:E, 2xro:F
7 5ayy:A 289 60 0.0709 0.0623 0.3000 0.41 5ayy:B, 5ayy:C, 5ayy:D, 5ayy:E, 5ayy:F, 5ayy:G, 5ayy:H, 5ayy:I, 5ayz:A, 5ayz:B, 5ayz:C, 5ayz:D, 5ayz:E, 5ayz:F, 5ayz:G, 5ayz:H, 5ayz:I, 5ayz:J, 5ayz:K, 5ayz:L, 4kww:A, 4kww:B, 4kww:C, 4kww:D, 4kww:E, 4kww:F
8 3t58:B 504 107 0.0984 0.0496 0.2336 0.94 4p2l:A, 4p2l:B, 3t58:A, 3t58:C, 3t58:D, 3t59:A, 3t59:B, 3t59:C, 3t59:D
9 7rr9:A 560 93 0.1142 0.0518 0.3118 1.4 7rr9:B, 7vx8:B, 7vx8:A
10 4wai:A 91 52 0.0669 0.1868 0.3269 2.0 4wai:C, 4wai:B, 4wai:D
11 5fog:D 284 53 0.0630 0.0563 0.3019 2.2 5fog:A, 5fog:B, 5fog:C, 5fol:A, 5fom:A
12 8pj1:t 472 39 0.0512 0.0275 0.3333 2.5 7d43:P, 6fec:S, 5k0y:S, 6k71:P, 6k72:P, 8oz0:E, 8pj2:t, 8ppl:It, 6yal:B, 6yam:B, 6yan:B
13 1y1x:A 182 70 0.0748 0.1044 0.2714 3.9 1y1x:B
14 6gaw:Ao 572 34 0.0472 0.0210 0.3529 3.9 6gaz:Ao
15 7tnb:AAA 353 53 0.0591 0.0425 0.2830 4.1
16 4dyn:A 437 29 0.0472 0.0275 0.4138 4.7 5b7b:A, 5b7b:C, 5b7b:D, 4bbl:D, 4bbl:F, 4bbl:H, 4bbl:J, 4bbl:L, 4bbl:N, 4bbl:P, 4bbl:R, 4bbl:T, 4bbl:V, 4bbl:X, 4bbl:A, 4bbl:C, 4bbl:E, 4bbl:G, 4bbl:I, 4bbl:K, 4bbl:M, 4bbl:O, 4bbl:Q, 4bbl:S, 4bbl:U, 4dya:A, 4dya:B, 4dyb:A, 4dyb:B, 4dyn:B, 4dyp:A, 4dyp:B, 6h9g:A, 6h9g:C, 6i54:A, 6i54:C, 6i7b:A, 6i7b:C, 6i7m:A, 6i7m:C, 3ro5:A, 3ro5:B, 3tg6:A, 3tg6:B
17 8pzp:A 470 29 0.0472 0.0255 0.4138 5.1 6j1u:A, 6j1u:C, 8pzq:A, 8pzq:C, 8pzq:B
18 4bbl:B 399 29 0.0472 0.0301 0.4138 5.2 4bbl:W, 6i85:A, 6i85:C
19 7dxp:B 418 31 0.0472 0.0287 0.3871 8.1 7dkg:B
20 1ft9:A 210 46 0.0512 0.0619 0.2826 8.7 1ft9:B, 4k8f:A, 4k8f:B, 4k8f:C, 4k8f:D
21 8fni:9 858 70 0.0709 0.0210 0.2571 9.3 8fnk:9
22 6v6s:k 370 50 0.0512 0.0351 0.2600 9.7 6v5v:g, 6v6s:a, 6v6s:b, 6v6s:c, 6v6s:d, 6v6s:e, 6v6s:f, 6v6s:g, 6v6s:h, 6v6s:i, 6v6s:j, 6v6s:l, 6v6s:m, 6v6s:t

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218