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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSE
KSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFAS
EIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNVIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRT
GEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTEPMVRNEKGLLTYTSWEDALSRVAGMLQNFEGNAVAAIAGGLVD
AEALVALKDLLNKVDSDNLCTEEIFPTEGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRKSWLHNDL
KVALIGSPVDLTYRYDHLGDSPKILQDIASGRHSFCEVLKDAKKPMVVLGSSALQRDDGAAILVAVSNMVQKIRVTTGVA
AEWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKMLFLLGADGGCITRQDLPKDCFIVYQGHHGDVGAPMADVILPGA
AYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDIEETNYFQQ
ASELAKLVNQEVLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEG

The query sequence (length=690) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7qso:G 700 690 0.9449 0.9314 0.9449 0.0 7ak5:G, 7ak6:G, 7b93:G, 8c2s:G, 8ca3:G, 8ca4:G, 8ca5:G, 7dgq:A, 7dgr:A, 7dgs:A, 7dgz:A, 7dh0:A, 7dkf:A2, 6g2j:G, 6g72:G, 5gpn:Y, 5gup:G, 8iao:G, 8iap:G, 8ib4:G, 8ib5:G, 8ib9:G, 8iba:G, 8ibd:G, 8ibe:G, 8ic2:G, 8ic3:G, 5lnk:3, 5o31:G, 8olt:G, 8om1:G, 7psa:G, 8pw5:3, 8pw6:3, 8pw7:3, 8q0a:G, 8q0f:G, 8q0j:G, 8q0m:G, 8q0o:G, 8q0q:G, 8q1p:G, 8q1u:G, 8q1y:G, 8q25:G, 8q45:G, 8q46:G, 8q47:G, 8q48:G, 8q49:G, 8q4a:G, 6q9d:S1, 6qa9:S1, 6qbx:S1, 6qc2:S1, 6qc3:S1, 6qc4:S1, 6qc5:S1, 6qc6:S1, 6qc7:S1, 6qc8:S1, 6qc9:S1, 6qca:S1, 6qcf:S1, 7qsd:G, 7qsk:G, 7qsl:G, 7qsm:G, 7qsn:G, 7r41:G, 7r42:G, 7r43:G, 7r44:G, 7r45:G, 7r46:G, 7r47:G, 7r48:G, 7r4c:G, 7r4d:G, 7r4f:G, 7r4g:G, 8rgp:3, 8rgq:3, 8rgr:3, 8rgt:3, 8ud1:1G, 8ueo:1G, 8uep:1G, 8ueq:1G, 8uer:1G, 8ues:1G, 8uet:1G, 8ueu:1G, 8uev:1G, 8uew:1G, 8uex:1G, 8uey:1G, 8uez:1G, 8ugh:1G, 8ugi:1G, 8ugj:1G, 8ugn:1G, 8ugn:5G, 8ugr:1G, 8ugr:5G, 7v2c:M, 7v2d:M, 7v2e:M, 7v2f:M, 7v2h:M, 7v2k:M, 7v2r:M, 7v30:M, 7v31:M, 7v32:M, 7v33:M, 7v3m:M, 7vb7:M, 7vbn:M, 7vbz:M, 7vwj:M, 7vxp:M, 7vxu:M, 7vy8:M, 7vya:M, 7vyf:M, 7vyh:M, 7vyn:M, 7vz1:M, 7vzv:M, 7vzw:M, 7w00:M, 7w0h:M, 7w0r:M, 7w0y:M, 7w1o:M, 7w1p:M, 7w1t:M, 7w1u:M, 7w1v:M, 7w1z:M, 7w20:M, 7w2k:M, 7w2l:M, 7w2r:M, 7w2u:M, 7w2y:M, 7w31:M, 7w32:M, 7w35:M, 7w4c:M, 7w4d:M, 7w4e:M, 7w4f:M, 7w4g:M, 7w4j:M, 7w4k:M, 7w4l:M, 7w4m:M, 7w4n:M, 7w4q:M, 5xtb:M, 5xtd:M, 5xth:M, 5xti:M, 5xti:BM, 7zd6:3, 7zdh:3, 7zdj:3, 7zdm:3, 7zdp:3, 7zeb:3, 6zk9:3, 6zkc:3, 6zkd:3, 6zke:3, 6zkf:3, 6zkg:3, 6zkh:3, 6zki:3, 6zkj:3, 6zkk:3, 6zkl:3, 6zkm:3, 6zkn:3, 6zko:3, 6zkp:3, 6zkq:3, 6zkr:3, 6zks:3, 6zkt:3, 6zku:3, 6zkv:3, 6zr2:G, 6ztq:G
2 8esz:S1 683 689 0.6232 0.6296 0.6241 0.0 8b9z:G, 8ba0:G, 8esw:S1
3 7arc:G 682 687 0.5725 0.5792 0.5750 0.0 7ard:G
4 7b0n:G 694 685 0.5449 0.5418 0.5489 0.0 6gcs:A, 7o6y:A, 7o71:A, 6rfq:A, 6rfr:A, 6rfs:A, 6y79:A, 6yj4:G
5 7zm7:A 711 698 0.5565 0.5401 0.5501 0.0 7zmb:A, 7zmg:A
6 6x89:S1 688 679 0.5580 0.5596 0.5670 0.0 8e73:S1
7 8gym:s1 689 690 0.5478 0.5486 0.5478 0.0 8b6f:AB, 8bqs:AB, 8gym:S1, 8gzu:s1, 8gzu:S1, 7tgh:S1
8 7a23:C 693 680 0.5377 0.5354 0.5456 0.0 7a24:C, 7aqr:G, 7ar7:G, 7ar8:G, 7arb:G, 8bed:G, 8bpx:G, 8bq5:G, 8bq6:G
9 8qby:G 666 694 0.4609 0.4775 0.4582 0.0
10 5lc5:G 685 202 0.2899 0.2920 0.9901 1.06e-139 5ldw:G, 5ldx:G
11 8e9h:G 782 411 0.2188 0.1931 0.3674 5.46e-69 8e9g:G, 8e9i:G
12 8e9h:G 782 75 0.0290 0.0256 0.2667 6.0 8e9g:G, 8e9i:G
13 4hea:3 756 651 0.2754 0.2513 0.2919 3.26e-65 2fug:3, 2fug:C, 2fug:L, 2fug:U, 4hea:D, 6i0d:3, 6i0d:D, 6i1p:3, 6i1p:D, 3i9v:3, 3i9v:C, 3iam:3, 3iam:C, 3ias:3, 3ias:C, 3ias:L, 3ias:U, 3m9s:3, 3m9s:C, 6q8o:3, 6q8o:D, 6q8w:3, 6q8w:D, 6q8x:3, 6q8x:D, 6y11:3, 6y11:D, 2ybb:3, 6ziy:3, 6zjl:3, 6zjn:3, 6zjy:3
14 7awt:G 907 705 0.2565 0.1951 0.2511 1.50e-55 7nyr:G, 7nyu:G, 7nyv:G, 7nz1:G, 7p61:G, 7p62:G, 7p63:G, 7p64:G, 7p69:G, 7p7c:G, 7p7e:G, 7p7j:G, 7p7k:G, 7p7l:G, 7p7m:G, 7z7r:G, 7z7s:G, 7z7t:G, 7z7v:G, 7z80:G, 7z83:G, 7z84:G, 7zc5:G, 7zci:G
15 8iuf:1A 352 277 0.1522 0.2983 0.3791 3.48e-51 8j9h:1A, 8j9i:1A, 8j9j:1A
16 7q5y:A 626 290 0.1391 0.1534 0.3310 1.96e-44 7q5y:G, 7q5y:M, 7q5y:S
17 7t30:A 666 659 0.2319 0.2402 0.2428 4.46e-40 7t2r:A, 7t2r:F, 7t30:F
18 6tg9:A 949 414 0.1609 0.1170 0.2681 6.28e-40 6tg9:E, 6tga:A, 6tga:E
19 6tg9:A 949 78 0.0304 0.0221 0.2692 0.026 6tg9:E, 6tga:A, 6tga:E
20 8a6t:A 571 208 0.1058 0.1278 0.3510 2.68e-31 8a6t:D, 8bew:A, 8bew:D
21 8a5e:A 583 219 0.1130 0.1338 0.3562 5.19e-29 8a5e:D, 7q4v:A, 7q4v:E, 7q4w:A, 7q4w:E
22 7p8n:a 642 205 0.0957 0.1028 0.3220 1.54e-27 7p5h:A, 7p5h:D, 7p5h:a, 7p5h:d, 7p8n:A, 7p91:a, 7p91:A, 7p92:A
23 6h8k:A 628 126 0.0855 0.0939 0.4683 1.56e-25
24 5xf9:B 234 238 0.1058 0.3120 0.3067 4.87e-24 5xf9:F, 5xfa:B, 5xfa:F
25 7vw6:A 913 451 0.1623 0.1227 0.2483 3.14e-22 7e5z:A, 8j83:A, 7xqw:A
26 7vw6:A 913 92 0.0449 0.0340 0.3370 8.97e-09 7e5z:A, 8j83:A, 7xqw:A
27 8oh5:C 1172 594 0.1913 0.1126 0.2222 8.69e-20 8oh5:F, 8oh5:I, 8oh5:L, 8oh9:C, 8oh9:F, 8oh9:I, 8oh9:L
28 8oh5:C 1172 101 0.0536 0.0316 0.3663 6.54e-16 8oh5:F, 8oh5:I, 8oh5:L, 8oh9:C, 8oh9:F, 8oh9:I, 8oh9:L
29 7qv7:S 571 76 0.0391 0.0473 0.3553 1.79e-08 7qv7:Y
30 7qv7:S 571 178 0.0551 0.0665 0.2135 0.11 7qv7:Y
31 7bkb:D 549 109 0.0551 0.0692 0.3486 1.63e-07 7bkb:d, 7bkc:D, 7bkc:d, 7bkd:D, 7bke:D
32 4xdd:A 582 208 0.0681 0.0808 0.2260 5.70e-07 8aio:A, 8aio:B, 8aj6:A, 8aj6:B, 8aln:A, 8aln:B, 8ap2:A, 8ap2:B, 5byq:A, 5byq:B, 5byr:A, 5byr:B, 5bys:A, 5bys:B, 1c4a:A, 1c4c:A, 3c8y:A, 8cjy:A, 8cjy:B, 1feh:A, 6gly:A, 6gly:B, 6glz:A, 6glz:B, 6gm0:A, 6gm0:B, 6gm1:A, 6gm1:B, 6gm2:A, 6gm2:B, 6gm3:A, 6gm3:B, 6gm4:A, 6gm4:B, 6gm8:A, 6gm8:B, 6h63:A, 6h63:B, 5la3:A, 5la3:B, 6n59:A, 6n6p:A, 6nac:A, 5oef:A, 5oef:B, 8pvm:A, 8pvm:B, 7qhf:A, 7qhf:B, 8qm3:A, 8qm3:B, 4xdc:A, 4xdc:B, 4xdd:B, 6yf4:A, 6yf4:B
33 2nya:A 791 61 0.0333 0.0291 0.3770 0.001 2nya:F
34 1fdi:A 715 92 0.0333 0.0322 0.2500 0.001 1aa6:A, 1fdo:A, 2iv2:X, 7z0t:A
35 3ml1:A 799 60 0.0348 0.0300 0.4000 0.002 3o5a:A
36 1ogy:A 789 60 0.0319 0.0279 0.3667 0.015 1ogy:C, 1ogy:E, 1ogy:G, 1ogy:I, 1ogy:K, 1ogy:M, 1ogy:O
37 2e7z:A 727 100 0.0362 0.0344 0.2500 0.099
38 2v45:A 723 134 0.0536 0.0512 0.2761 0.13 2jim:A, 2jio:A, 2jip:A, 2jiq:A, 2jir:A, 2nap:A, 2v3v:A
39 2v45:A 723 53 0.0261 0.0249 0.3396 0.42 2jim:A, 2jio:A, 2jip:A, 2jiq:A, 2jir:A, 2nap:A, 2v3v:A
40 2ivf:A 912 49 0.0290 0.0219 0.4082 0.53
41 4aay:A 843 120 0.0478 0.0391 0.2750 1.8 4aay:C, 4aay:E, 4aay:G, 8ccq:A, 8ccq:C, 8ccq:E, 8ccq:G, 8ed4:A, 8ed4:C, 8ed4:E, 8ed4:G, 5nqd:A, 5nqd:C, 5nqd:E, 5nqd:G
42 5chc:A 895 56 0.0275 0.0212 0.3393 1.8 5ch7:A, 5ch7:C, 5ch7:E, 5chc:C, 5chc:E, 5e7o:A, 5e7o:C, 5e7o:E, 5e7o:G, 5e7o:I, 5e7o:K, 4ydd:A, 4ydd:C, 4ydd:E
43 8que:C 697 111 0.0319 0.0316 0.1982 3.1
44 2wz8:A 135 63 0.0304 0.1556 0.3333 4.2
45 6icm:D 87 44 0.0232 0.1839 0.3636 4.7
46 2d7d:A 621 77 0.0275 0.0306 0.2468 5.7 2nmv:A, 3v4r:B, 3v4r:A
47 4rji:C 555 144 0.0609 0.0757 0.2917 9.6 4rji:A, 4rji:B, 4rji:D, 4rjj:A, 4rjj:B, 4rjj:C, 4rjj:D, 4rjj:E, 4rjj:F, 4rjj:G, 4rjj:H, 4rjk:A, 4rjk:B, 4rjk:C, 4rjk:D, 4rjk:E, 4rjk:F, 4rjk:G, 4rjk:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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