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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ASEVPQVVSLDPTSIPIEYNTPIHDIKVQVYDIKGGCNVEEGLTIFLVNNPGKENGPVKISSKVNDKQVSEFLKDENMEK
FNVKLGTSKHFYMFNDNKNSVAVGYVGCGSVADLSEADMKRVVLSLVTMLHDNKLSKLTVVFEINVDKNLFRFFLETLFY
EYMTDERFKSNVNMEYIKHLGVYINNADTYKEEVEKARVYYFGTYYASQLIAAPSNYCNPVSLSNAAVELAQKLNLEYKI
LGVKELEELKMGAYLSVGKGSMYPNKFIHLTYKSKGDVKKKIALVGKGITFDSGGYNLKAAPGSMIDLMKFDMSGCAAVL
GCAYCVGTLKPENVEIHFLSAVCENMVSKNSYRPGDIITASNGKTIEVGNTDAEGRLTLADALVYAEKLGVDYIVDIATL
TGAMLYSLGTSYAGVFGNNEELINKILQSSKTSNEPVWWLPIINEYRATLNSKYADINQISSSVKASSIVASLFLKEFVQ
NTAWAHIDIAGVSWNFKARKPKGFGVRLLTEFVLND

The query sequence (length=516) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ez4:C 525 519 1.0000 0.9829 0.9942 0.0 5cbm:A, 5cbm:B, 5cbm:C, 5cbm:D, 5cbm:E, 5cbm:F, 5cbm:G, 5cbm:H, 5cbm:I, 5cbm:J, 5cbm:K, 5cbm:L, 6ee2:A, 6ee2:B, 6ee2:C, 6ee2:D, 6ee2:E, 6ee2:F, 6ee2:G, 6ee2:H, 6ee2:I, 6ee2:J, 6ee2:K, 6ee2:L, 6eee:A, 6eee:B, 6eee:C, 6eee:D, 6eee:E, 6eee:F, 6eee:G, 6eee:H, 6eee:I, 6eee:J, 6eee:K, 6eee:L, 8ez4:A, 8ez4:B, 8ez4:D, 8ez4:E, 8ez4:F, 8ez4:G, 8ez4:H, 8ez4:I, 8ez4:J, 8ez4:K, 8ez4:L, 4k3n:A, 4k3n:B, 4k3n:C, 4k3n:D, 4k3n:E, 4k3n:F, 4k3n:G, 4k3n:H, 4k3n:I, 4k3n:J, 4k3n:K, 4k3n:L, 3kqx:A, 3kqx:B, 3kqx:C, 3kqx:D, 3kqx:E, 3kqx:F, 3kqx:G, 3kqx:H, 3kqx:I, 3kqx:J, 3kqx:K, 3kqx:L, 3kqz:A, 3kqz:B, 3kqz:C, 3kqz:D, 3kqz:E, 3kqz:F, 3kqz:G, 3kqz:H, 3kqz:I, 3kqz:J, 3kqz:K, 3kqz:L, 3kr4:A, 3kr4:B, 3kr4:C, 3kr4:D, 3kr4:E, 3kr4:F, 3kr4:G, 3kr4:H, 3kr4:I, 3kr4:J, 3kr4:K, 3kr4:L, 3kr5:A, 3kr5:B, 3kr5:C, 3kr5:D, 3kr5:E, 3kr5:F, 3kr5:G, 3kr5:H, 3kr5:I, 3kr5:J, 3kr5:K, 3kr5:L, 4r6t:A, 4r6t:B, 4r6t:C, 4r6t:D, 4r6t:E, 4r6t:F, 4r6t:G, 4r6t:H, 4r6t:I, 4r6t:J, 4r6t:K, 4r6t:L, 4r76:A, 4r76:B, 4r76:C, 4r76:D, 4r76:E, 4r76:F, 4r76:G, 4r76:H, 4r76:I, 4r76:J, 4r76:K, 4r76:L, 4r7m:A, 4r7m:B, 4r7m:C, 4r7m:D, 4r7m:E, 4r7m:F, 4r7m:G, 4r7m:H, 4r7m:I, 4r7m:J, 4r7m:K, 4r7m:L, 7rie:A, 7rie:B, 7rie:C, 7rie:D, 7rie:E, 7rie:F, 7rie:G, 7rie:H, 7rie:I, 7rie:J, 7rie:K, 7rie:L, 7srv:A, 7srv:B, 7srv:C, 7srv:D, 7srv:E, 7srv:F, 8svm:A, 8svm:B, 8svm:C, 8svm:D, 8svm:E, 8svm:F, 8svm:G, 8svm:H, 8svm:I, 8svm:J, 8svm:K, 8svm:L, 8sw9:A, 8sw9:B, 8sw9:C, 8sw9:D, 8sw9:E, 8sw9:F, 8sw9:G, 8sw9:H, 8sw9:I, 8sw9:J, 8sw9:K, 8sw9:L, 7t3v:A, 7t3v:B, 7t3v:C, 7t3v:D, 7t3v:E, 7t3v:F, 3t8w:A, 3t8w:B, 3t8w:E, 3t8w:C, 3t8w:D, 3t8w:F, 3t8w:G, 3t8w:H, 3t8w:K, 3t8w:I, 3t8w:J, 3t8w:L, 4x2t:A, 4x2t:B, 4x2t:C, 4x2t:D, 4x2t:E, 4x2t:F, 4x2t:G, 4x2t:H, 4x2t:I, 4x2t:J, 4x2t:K, 4x2t:L, 4zx8:A, 4zx8:B, 4zx8:C, 4zx8:D, 4zx8:E, 4zx8:F, 4zx8:G, 4zx8:H, 4zx8:I, 4zx8:J, 4zx8:K, 4zx8:L, 4zx9:A, 4zx9:B, 4zx9:C, 4zx9:D, 4zx9:E, 4zx9:F, 4zx9:G, 4zx9:H, 4zx9:I, 4zx9:J, 4zx9:K, 4zx9:L, 4zy0:A, 4zy0:B, 4zy0:C, 4zy0:D, 4zy0:E, 4zy0:F, 4zy0:G, 4zy0:H, 4zy0:I, 4zy0:J, 4zy0:K, 4zy0:L, 4zy1:A, 4zy1:B, 4zy1:C, 4zy1:D, 4zy1:E, 4zy1:F, 4zy1:G, 4zy1:H, 4zy1:I, 4zy1:J, 4zy1:K, 4zy1:L, 4zy2:A, 4zy2:B, 4zy2:C, 4zy2:D, 4zy2:E, 4zy2:F, 4zy2:G, 4zy2:H, 4zy2:I, 4zy2:J, 4zy2:K, 4zy2:L, 4zyq:A, 4zyq:B, 4zyq:C, 4zyq:D, 4zyq:E, 4zyq:F, 4zyq:G, 4zyq:H, 4zyq:I, 4zyq:J, 4zyq:K, 4zyq:L
2 7k5k:A 545 545 0.7636 0.7229 0.7229 0.0 7k5k:B, 7k5k:C, 7k5k:D, 7k5k:E, 7k5k:F, 6wvv:A, 6wvv:B, 6wvv:C, 6wvv:D, 6wvv:E
3 6wvv:F 497 516 0.7461 0.7746 0.7461 0.0 6wvv:G, 6wvv:H, 6wvv:I, 6wvv:J, 6wvv:L
4 6wvv:K 440 514 0.7054 0.8273 0.7082 0.0
5 4ksi:A 517 358 0.2965 0.2959 0.4274 1.30e-80 5d8n:A, 5d8n:B, 5d8n:C
6 3h8f:A 497 372 0.2868 0.2978 0.3978 1.76e-78 3h8f:B, 3h8f:C, 3h8f:D, 3h8f:E, 3h8f:F, 3h8g:F, 3h8g:A, 3h8g:B, 3h8g:C, 3h8g:D, 3h8g:E
7 8pz0:A 500 370 0.2868 0.2960 0.4000 7.96e-74 8pzm:A, 8pzy:A, 8pzy:B, 8pzy:C, 8pzy:D, 8pzy:E, 8pzy:F
8 7y1s:A 494 400 0.2810 0.2935 0.3625 1.42e-73
9 1gyt:A 503 471 0.3081 0.3161 0.3376 1.38e-70 1gyt:B, 1gyt:C, 1gyt:D, 1gyt:E, 1gyt:F, 1gyt:G, 1gyt:H, 1gyt:I, 1gyt:J, 1gyt:K, 1gyt:L
10 3jru:B 490 316 0.2578 0.2714 0.4209 1.09e-69 3jru:A
11 8d1x:D 469 327 0.2519 0.2772 0.3976 5.79e-66 8d1x:A, 8d1x:B, 8d1x:C, 8d1x:E, 8d1x:F
12 2ewb:A 486 335 0.2481 0.2634 0.3821 4.67e-64 1bll:E, 1bpm:A, 1bpn:A, 2j9a:A, 1lam:A, 1lan:A, 1lap:A, 1lcp:A, 1lcp:B
13 6ome:A 499 445 0.2888 0.2986 0.3348 1.04e-63
14 4zla:A 485 369 0.2888 0.3072 0.4038 5.64e-62 4zi6:A, 4zi6:B, 4zi6:C, 4zi6:D, 4zi6:E, 4zi6:F, 4zla:B, 4zla:C, 4zla:D, 4zla:E, 4zla:F
15 6ov8:A 429 323 0.2229 0.2681 0.3560 2.17e-51 6oad:A, 6oad:B, 6oad:C, 6oad:D, 6oad:E, 6oad:F, 6oad:G, 6oad:H, 6oad:I, 6oad:J, 6oad:K, 6oad:L, 6ov8:B, 6ov8:C, 6ov8:D, 6ov8:E, 6ov8:F
16 5ntg:A 512 322 0.2190 0.2207 0.3509 3.32e-48 5ntg:B
17 5lhk:A 455 320 0.2209 0.2505 0.3563 1.08e-44
18 5ntd:G 520 319 0.2054 0.2038 0.3323 2.32e-40 4efd:F, 5nsm:A, 5nsm:B, 5nsm:C, 5nsm:D, 5nsm:E, 5nsm:F, 5nsm:G, 5nsm:H, 5nsm:I, 5nsm:J, 5nsm:K, 5nsm:L, 5nsq:A, 5nsq:B, 5nsq:C, 5nsq:D, 5nsq:E, 5nsq:F, 5ntd:A, 5ntd:B, 5ntd:D, 5ntd:C, 5ntd:E, 5ntd:F, 5ntd:H, 5ntd:I, 5ntd:J, 5ntd:K, 5ntd:L
19 2hc9:A 489 292 0.1899 0.2004 0.3356 1.81e-34
20 5nth:A 537 325 0.1880 0.1806 0.2985 1.49e-31
21 1y7i:B 262 112 0.0581 0.1145 0.2679 0.37 1xkl:A, 1xkl:B, 1xkl:C, 1xkl:D, 1y7i:A
22 7eor:A 745 81 0.0446 0.0309 0.2840 1.3 7eor:C, 7yfi:B
23 6vvg:A 267 55 0.0368 0.0712 0.3455 2.1 6vvg:B
24 4oxi:A 526 26 0.0233 0.0228 0.4615 2.7
25 8xku:C 921 47 0.0291 0.0163 0.3191 4.8 8xkv:C
26 8pjb:A 962 82 0.0388 0.0208 0.2439 5.5 8b9g:A, 8b9k:A, 8pjj:A
27 6org:A 450 77 0.0446 0.0511 0.2987 5.7 6or4:A, 6or4:B, 6orf:A, 6orf:B, 6org:B, 6orh:A, 6orh:B
28 5aor:A 1009 82 0.0388 0.0198 0.2439 6.1 5aor:B, 8b9i:A, 8b9j:A
29 7eoq:A 783 82 0.0446 0.0294 0.2805 6.7 7eoq:C, 7eou:A, 7eou:C, 7eu7:B, 7eu7:D, 5tpw:B, 5tq2:B
30 7qep:D4 127 64 0.0388 0.1575 0.3125 6.8
31 5xn9:A 138 89 0.0465 0.1739 0.2697 7.6 5xn9:B, 5xna:A, 5xna:B
32 5u8c:B 283 80 0.0426 0.0777 0.2750 9.2 2a5s:A, 2a5t:B, 5dex:B, 5h8f:A, 5h8h:A, 5h8n:A, 5h8q:A, 5i2k:A, 5i2n:A, 5i56:B, 5i57:B, 5i58:B, 5i59:B, 5jty:B, 4jwx:A, 5kcj:A, 5kdt:A, 4nf4:B, 4nf5:B, 4nf6:B, 4nf8:B, 6odl:A, 6odl:B, 6ovd:B, 6ove:B, 5tp9:A, 5tpa:A, 6usu:B, 6usv:B, 6uz6:B, 6uzg:B, 6uzr:B, 6uzw:B, 6uzx:B, 5vih:B, 5vii:B, 5vij:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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