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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ASETRKAYTTKMIPRSHDRMKLLGNFMDYLMDGTPIFFELWNQFGGGIDRDIISGTANKDKISDDLLLAVNWFKVMPINS
KPQGVSPSNLANLFQQYSGSEPDIQAQEYFASNFDTEKHQWKDMRVEYERLLAELQLSRSDMHHDLKLMYKEKCIGLSLS
TAHYITSVMCMEKIKAFLASKVGPYYLGSYSAMLENALSPIKGMTTKNCKFVLKQIDAKNDIKYENEPFGKIVEGVKWVL
HPHHIGESNIKTLWEDLNAIHSKYEEDIASLSEDKKEKRIKVYQGDVCQTINTYCEEVGKEAKTPLVQLLRYLYSRKDDI
AVDKIIDGITFLSKKHKVEKQKINPVIQKYPSFNFGNNSKLLGKIISPKDKLKHNLKCNRNQVDNYIWIEIKVLNTKTMR
WEKHHYALSSTRFLEEVYYPATSYEGKPALSAEQIEQIRSAPVGLRKVKKRQMRLEAARQQNLLPRYTWGKDFNINICKR
GNNFEVTLATKVKKKKEKNYKVVLGYDANIVRKNTYAAIEAHANGDGVIDYNDLPVKPIESGFVTVESQVRDKSYDQLSY
NGVKLLYCKPHVESRRSFLEKYNMKDFEAIADDETSLYYFNMKYCKLLQSSIRNHSSQAKEYREEIFELLRDGKLSVLKL
SSLSNLSFVMFKVAKSLIGTYFGHLLKKAPPITDEDKQKADPEMFALRLALEEKRLNKVKSKKEVIANKIVAKALELRDK
YGPVLIKGENISDTTKKGKKSSTNSFLMDWLARGVANKVKEMVMMHQGLEFVEVNPNFTSHQDPFVHKNPENTFRARYSR
CTPSELTEKNRKEILSFLSDKPSKRPTNAYYNEGAMAFLATYGLKKNDVLGVSLEKFKQIMANILHQRSEDQLLFPSRGG
MFYLATYKLDADATSVNWNGKQFWVCNADLVAAYNVGLVDIQKDFKKK

The query sequence (length=928) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6w64:A 928 928 1.0000 1.0000 1.0000 0.0
2 6w62:A 910 948 0.9558 0.9747 0.9357 0.0
3 6w5c:A 1023 767 0.8179 0.7419 0.9896 0.0
4 6w5c:A 1023 169 0.1821 0.1652 1.0000 4.14e-110
5 7d8c:A 1057 811 0.8147 0.7152 0.9322 0.0
6 7d8c:A 1057 169 0.1821 0.1599 1.0000 7.69e-110
7 7eu9:A 1078 804 0.8136 0.7004 0.9391 0.0 7d2l:A, 7d3j:A
8 7eu9:A 1078 169 0.1821 0.1568 1.0000 1.44e-109 7d2l:A, 7d3j:A
9 6ltp:G 923 980 0.2791 0.2806 0.2643 4.11e-85 6ltp:A
10 6lu0:A 937 997 0.2737 0.2711 0.2548 2.19e-70
11 6ltr:A 1037 806 0.2284 0.2044 0.2630 1.18e-61 6ltu:A
12 6ltr:A 1037 159 0.0506 0.0453 0.2956 9.45e-17 6ltu:A
13 2y9w:A 391 177 0.0431 0.1023 0.2260 2.0 2y9w:B, 2y9x:A, 2y9x:B, 2y9x:C, 2y9x:D
14 8dml:B 133 72 0.0237 0.1654 0.3056 2.0 8dml:D, 8dml:F, 8dml:H, 5kew:B, 5kew:D, 5kew:F
15 6yxy:EQ 471 46 0.0183 0.0361 0.3696 2.6
16 6qjz:A 504 75 0.0205 0.0377 0.2533 2.9
17 8hr6:A 359 118 0.0366 0.0947 0.2881 4.2 8hr6:B
18 3avt:A 1203 147 0.0356 0.0274 0.2245 6.4 7abz:6, 5afi:z, 3agp:A, 3agq:A, 3avu:A, 3avv:A, 3avw:A, 3avx:A, 3avy:A, 7bbn:A, 7bbn:B, 2bvn:A, 2bvn:B, 1efm:A, 1etu:A, 4fwt:A, 2hcj:A, 2hcj:B, 2hdn:A, 2hdn:B, 2hdn:C, 2hdn:D, 2hdn:E, 2hdn:F, 2hdn:G, 2hdn:H, 2hdn:I, 2hdn:J, 2hdn:K, 2hdn:L, 5i4r:C, 5i4r:D, 5i4r:G, 5i4r:H, 3mmp:G, 5opd:A, 5opd:B, 4pc2:A, 4pc2:B, 4pc3:A, 4pc3:B, 4pc6:A, 4pc6:B, 4pc7:A, 3u6b:B, 3u6b:A, 3vnu:A, 3vnv:A, 6wd4:8, 6wd7:8, 6wd9:8, 6wda:8
19 6yjo:A 475 54 0.0162 0.0316 0.2778 8.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218