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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ASELLFYVNGRKVIEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISRYNPITKRIRHHPANACLIPICSLYG
AAVTTVEGIGSTHTRIHPVQERIAKCHGTQCGFCTPGMVMSIYTLLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKT
FCKPKLFAEEEFLPLDPTQELIFPPELMIMAEKQSQRTRVFGSERMMWFSPVTLKELLEFKFKYPQAPVIMGNTSVGPEV
KFKGVFHPVIISPDRIEELSVVNHAYNGLTLGAGLSLAQVKDILADVVQKLPEEKTQMYHALLKHLGTLAGSQIRNMASL
GGHIISRHPDSDLNPILAVGNCTLNLLSKEGKRQIPLNEQFLSKCPNADLKPQEILVSVNIPYSRKWEFVSAFRQAQRQE
NALAIVNSGMRVFFGEGDGIIRELCISYGGVGPATICAKNSCQKLIGRHWNEQMLDIACRLILNEVSLLGSAPGGKVEFK
RTLIISFLFKFYLEVSQILKKMDPVHYPSLADKYESALEDLHSKHHCSTLKYQNQHPEDPIGHPIMHLSGVKHATGEAIY
CDDMPLVDQELFLTFVTSSRAHAKIVSIDLSEALSMPGVVDIMTAEHLSDVNSFCFFTEAEKFLATDKVFCVGQLVCAVL
ADSEVQAKRAAKRVKIVYQDLEPLILTIEESIQHNSSFKPERKLEYGNVDEAFKVVDQILEGEIHMGGQEHFYMETQSML
VVPKGEDQEMDVYVSTQFPKYIQDIVASTLKLPANKVMCHVRRVGGAFGGKVLKTGIIAAVTAFAANKHGRAVRCVLERG
EDMLITGGRHPYLGKYKAGFMNDGRILALDMEHYSNAGASLDESLFVIEMGLLKMDNAYKFPNLRCRGWACRTNLPSNTA
FRGFGFPQAALITESCITEVAAKCGLSPEKVRIINMYKEIDQTPYKQEINAKNLIQCWRECMAMSSYSLRKVAVEKFNAE
NYWKKKGLAMVPLKFPVGLGSRAAGQAAALVHIYLDGSVLVTHGGIEMGQGVHTKMIQVVSRELRMPMSNVHLRGTSTET
VPNANISGGSVVADLNGLAVKDACQTLLKRLEPIISKNPKGTWKDWAQTAFDESINLSAVGYFRGYESDMNWEKGEGQPF
EYFVYGAACSEVEIDCLTGDHKNIRTDIVMDVGCSINPAIDIGQIEGAFIQGMGLYTIEELNYSPQGILHTHGPDQYKIP
AICDMPTELHIALLPPSQNSNTLYSSKGLGESGVFLGCSVFFAIHDAVSAARQERGLHLTLNSPLTPEKIRMACEDKFTK
MIPRDEPGSYVPWNV

The query sequence (length=1295) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7orc:B 1299 1299 0.9992 0.9962 0.9962 0.0 5epg:A, 7opn:A, 7opn:B, 7orc:A, 6q6q:A, 4uhw:A, 4uhx:A
2 8emt:A 1254 1297 0.9653 0.9968 0.9638 0.0
3 8emt:B 1221 1295 0.9405 0.9975 0.9405 0.0
4 3zyv:B 1262 1299 0.6178 0.6339 0.6159 0.0 3zyv:A, 3zyv:C, 3zyv:D
5 1fo4:A 1299 1309 0.5143 0.5127 0.5088 0.0 3am9:A, 3am9:B, 3amz:A, 3amz:B, 3b9j:B, 3b9j:C, 3b9j:J, 3b9j:K, 3bdj:A, 3bdj:B, 3etr:B, 3etr:C, 3etr:M, 3etr:N, 3eub:B, 3eub:C, 3eub:K, 3eub:L, 3eub:T, 3eub:U, 3eub:3, 3eub:4, 1fiq:B, 1fo4:B, 8j79:A, 8j79:B, 1n5x:A, 1n5x:B, 3nrz:B, 3nrz:C, 3nrz:K, 3nrz:L, 3ns1:B, 3ns1:C, 3ns1:K, 3ns1:L, 3nvv:B, 3nvv:C, 3nvv:K, 3nvv:L, 3nvw:B, 3nvw:C, 3nvw:K, 3nvw:L, 3nvy:B, 3nvy:C, 3nvy:K, 3nvy:L, 3nvz:B, 3nvz:C, 3nvz:K, 3nvz:L, 3sr6:B, 3sr6:C, 3sr6:K, 3sr6:L, 3una:A, 3una:B, 3unc:A, 3unc:B, 3uni:A, 3uni:B, 1v97:A, 1v97:B, 1vdv:A, 1vdv:B
6 2e1q:A 1307 1320 0.5127 0.5080 0.5030 0.0 6a7x:A, 6a7x:B, 6abu:A, 6abu:B, 6ac1:A, 6ac1:B, 6ac4:A, 6ac4:B, 6ad4:A, 6ad4:B, 6adj:A, 6adj:B, 6aju:A, 6aju:F, 3an1:A, 3an1:B, 3b9j:A, 3b9j:I, 2ckj:B, 2ckj:C, 2ckj:D, 2e1q:B, 2e1q:C, 2e1q:D, 2e3t:A, 2e3t:B, 3etr:A, 3etr:L, 3eub:A, 3eub:J, 3eub:S, 3eub:2, 1fiq:A, 3nrz:A, 3nrz:J, 3ns1:A, 3ns1:J, 3nvv:A, 3nvv:J, 3nvw:A, 3nvw:J, 3nvy:A, 3nvy:J, 3nvz:A, 3nvz:J, 3sr6:A, 3sr6:J, 1wyg:A, 4yrw:A, 4yrw:B, 4ysw:A, 4ysw:B, 4yty:A, 4yty:B, 4ytz:A, 4ytz:B
7 2ckj:A 1264 1288 0.5058 0.5182 0.5085 0.0
8 3ax7:A 1225 1294 0.4919 0.5200 0.4923 0.0 3ax7:B, 3ax9:A, 3ax9:B
9 7px0:B 1253 1298 0.3012 0.3113 0.3005 1.08e-152 7px0:A, 7px0:C, 7px0:D
10 1jro:B 760 760 0.2216 0.3776 0.3776 9.52e-141 1jro:D, 1jro:F, 1jro:H, 1jrp:B, 1jrp:D, 1jrp:F, 1jrp:H, 2w3r:B, 2w3r:D, 2w3r:F, 2w3r:H, 2w3s:B, 2w3s:D, 2w3s:F, 2w3s:H, 2w54:B, 2w54:D, 2w54:F, 2w54:H, 2w55:B, 2w55:D, 2w55:F, 2w55:H
11 7dqx:D 770 784 0.1614 0.2714 0.2666 1.03e-50 7dqx:A
12 1rm6:A 761 764 0.1583 0.2694 0.2683 2.98e-50 1rm6:D, 1sb3:A, 1sb3:D
13 4c7y:A 907 791 0.1583 0.2260 0.2592 1.19e-44 4c7z:A, 4c80:A, 3fah:A, 3fc4:A, 3l4p:A, 1sij:A, 4us8:A, 4us9:A, 4usa:A, 1vlb:A
14 4c7y:A 907 158 0.0479 0.0684 0.3924 8.07e-22 4c7z:A, 4c80:A, 3fah:A, 3fc4:A, 3l4p:A, 1sij:A, 4us8:A, 4us9:A, 4usa:A, 1vlb:A
15 1jro:A 450 467 0.1019 0.2933 0.2827 2.53e-40 1jro:C, 1jro:E, 1jro:G, 1jrp:A, 1jrp:C, 1jrp:E, 1jrp:G, 2w3r:A, 2w3r:C, 2w3r:E, 2w3r:G, 2w3s:A, 2w3s:C, 2w3s:E, 2w3s:G, 2w54:A, 2w54:C, 2w54:E, 2w54:G, 2w55:A, 2w55:C, 2w55:E, 2w55:G
16 3hrd:A 420 386 0.0888 0.2738 0.2979 1.89e-39 3hrd:E
17 1dgj:A 906 809 0.1552 0.2219 0.2485 2.74e-38
18 1dgj:A 906 143 0.0448 0.0640 0.4056 3.02e-22
19 1t3q:B 786 737 0.1367 0.2252 0.2402 4.26e-35 1t3q:E
20 1sb3:C 161 167 0.0541 0.4348 0.4192 7.35e-32 1rm6:C, 1rm6:F, 1sb3:F
21 4zoh:A 701 748 0.1390 0.2568 0.2406 1.39e-30
22 4zoh:C 161 157 0.0463 0.3727 0.3822 2.71e-29
23 1ffu:D 156 150 0.0502 0.4167 0.4333 4.27e-29 1ffu:A, 1ffv:A, 1ffv:D
24 1n5w:A 161 150 0.0440 0.3540 0.3800 8.00e-28 1n5w:D, 1n60:A, 1n60:D, 1n61:A, 1n61:D, 1n62:A, 1n62:D, 1n63:A, 1n63:D, 1zxi:A, 1zxi:D
25 1ffu:B 797 736 0.1328 0.2158 0.2337 6.31e-27 1ffu:E, 1ffv:B, 1ffv:E
26 5y6q:A 157 156 0.0463 0.3822 0.3846 1.99e-26
27 1n63:B 805 774 0.1413 0.2273 0.2364 2.71e-26 1n5w:B, 1n5w:E, 1n60:B, 1n60:E, 1n61:B, 1n61:E, 1n62:B, 1n62:E, 1n63:E, 1zxi:B, 1zxi:E
28 5g5g:C 731 761 0.1436 0.2544 0.2444 6.39e-26 5g5h:C
29 1t3q:A 162 140 0.0417 0.3333 0.3857 1.08e-25 1t3q:D
30 7dqx:C 160 143 0.0402 0.3250 0.3636 2.10e-25 7dqx:F
31 8gy3:B 154 154 0.0440 0.3701 0.3701 3.62e-24
32 5g5g:A 175 169 0.0494 0.3657 0.3787 9.01e-24 5g5h:A
33 3hrd:D 160 141 0.0402 0.3250 0.3688 3.63e-20 3hrd:H
34 3hrd:B 330 336 0.0695 0.2727 0.2679 1.18e-19 3hrd:F
35 5y6q:C 748 755 0.1236 0.2139 0.2119 5.71e-13
36 4zoh:B 274 277 0.0456 0.2153 0.2130 1.62e-12
37 1t3q:C 285 206 0.0386 0.1754 0.2427 1.34e-08 1t3q:F
38 3hrd:G 292 245 0.0448 0.1986 0.2367 2.18e-08 3hrd:C
39 8gy3:C 732 290 0.0525 0.0929 0.2345 4.42e-08
40 8gy3:C 732 165 0.0355 0.0628 0.2788 0.027
41 7dqx:E 293 211 0.0394 0.1741 0.2417 6.22e-05 7dqx:B
42 5y6q:B 330 277 0.0486 0.1909 0.2274 2.11e-04
43 1ffu:C 287 214 0.0378 0.1707 0.2290 0.044 1ffu:F, 1ffv:C, 1ffv:F
44 1rm6:B 323 317 0.0479 0.1920 0.1956 0.42 1rm6:E, 1sb3:B, 1sb3:E
45 1n5w:C 287 74 0.0147 0.0662 0.2568 0.49 1n5w:F, 1n60:C, 1n60:F, 1n61:C, 1n61:F, 1n62:C, 1n62:F, 1n63:C, 1n63:F, 1zxi:C, 1zxi:F
46 1lh0:A 213 54 0.0170 0.1033 0.4074 2.6 1lh0:B, 1opr:A, 1oro:A, 1sto:A
47 4ff7:A 247 66 0.0131 0.0688 0.2576 2.7 4ff7:B, 7tim:A, 7tim:B, 2ypi:A, 2ypi:B, 3ypi:A, 3ypi:B
48 7zpq:CA 1742 44 0.0108 0.0080 0.3182 8.4 7zrs:CA, 7zuw:CA
49 7f19:A 444 38 0.0108 0.0315 0.3684 8.7 2yxv:A, 2yxv:B, 2yxw:A, 2yxw:B
50 5b7e:A 477 38 0.0108 0.0294 0.3684 9.0 5b7f:A, 5b7m:A, 5b7m:B, 5b7m:C, 4ef3:A, 2fqd:A, 2fqe:A, 2fqf:A, 2fqg:A, 6im7:A, 1kv7:A, 1n68:A, 3nsc:A, 3nsd:A, 3nsy:A, 3nt0:A, 3pau:A, 3pav:A, 1pf3:A, 3qqx:A, 5ys1:A, 5ys5:A
51 3od3:A 488 38 0.0108 0.0287 0.3684 9.2 4e9q:A, 4e9r:A, 4e9s:A, 4e9t:A, 7f0v:A, 7f0v:B, 4hak:A, 4hal:A, 4ner:A, 3uaa:A, 3uab:A, 3uac:A, 3uad:A, 3uae:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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