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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ARLLLVSNRLPIYDFSMSGGLVSGFQWYGWPGLEVPEPVVKQRLKDEYGAIPVFIDDELADRHYNGFSNSILWPLFHYHP
GEITFDESAWEAYKEANRLFAKAVAKEVQDGDLIWVHDYHLMLLPEMLREEIGDSKENVKIGFFLHTPFPSSEIYRILPV
RNELLLGVLHCDLIGFHTYDYTRHFLSACSRLLGLATTPNGIEFQGKVIACGAFPIGIDPEKFQEGLKKEKVQKRIAQLE
QKFQGVKLMVGVDRLDYIKGVPQKLHALEVFLSDHPEWVGKVVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTVE
FMPIHFLHKSVNFDELIALYAVSDACIVSSTRDGMNLVAYEYIASQQKRHGVLVLSEFAGAAQSLNGSIIINPWNTEELA
GAYQEAVTMSDEQRALNFSKLDKYVNKYTSAFWGQSFVTELNRISA

The query sequence (length=446) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5hvm:B 452 452 0.9888 0.9757 0.9757 0.0 5hvm:A
2 6jbr:A 465 466 0.8139 0.7806 0.7790 0.0 6jbr:B, 6jbr:D, 6jbr:F, 6jbr:H, 6jbr:K, 6jbr:M, 6jbr:O, 6jbw:A, 6jbw:B
3 5hvo:A 459 459 0.7915 0.7691 0.7691 0.0 5hvo:B, 5hvo:C, 5hvo:D
4 5hut:A 469 468 0.6906 0.6567 0.6581 0.0 5hut:B, 5huu:A, 5huu:B, 5huv:A, 5huv:B, 5hvl:A, 5hvl:B
5 8fhw:A 432 444 0.6592 0.6806 0.6622 0.0 8fhw:B, 8fhw:C, 8fhw:D
6 2wtx:D 457 458 0.3632 0.3545 0.3537 2.01e-89 1gz5:A, 1gz5:B, 1gz5:C, 1gz5:D, 1uqt:A, 1uqt:B, 1uqu:A, 2wtx:A, 2wtx:B, 2wtx:C
7 5jio:A 467 465 0.3610 0.3448 0.3462 1.71e-87 5k41:A, 5k42:A, 5k44:A, 5k5c:A, 5l3k:A, 5l3k:B, 5l3k:C, 5l3k:D, 5l3k:E, 5l3k:F, 5l3k:G, 5l3k:H
8 5tvg:A 468 464 0.3744 0.3568 0.3599 6.05e-86 5tvg:B, 5tvg:C, 5tvg:D, 5tvg:E, 5tvg:F, 5tvg:G, 5tvg:H, 5uof:B
9 5v0t:E 457 462 0.3498 0.3414 0.3377 1.27e-80 5v0t:A, 5v0t:B, 5v0t:C, 5v0t:D, 5v0t:F, 5v0t:G, 5v0t:H
10 8iye:A 475 337 0.1951 0.1832 0.2582 2.38e-19 4f96:B, 4f96:A, 4f97:A, 4f97:B, 4f9f:A, 4f9f:D, 4f9f:B, 4f9f:C, 4f9f:E, 4f9f:F, 8iye:B, 8iyf:A, 8iyf:B, 3t5t:A, 3t5t:B, 3t7d:A, 3t7d:B, 3vdn:B
11 6lkx:A 441 74 0.0561 0.0567 0.3378 0.37 6jdr:A, 6jds:A, 6jdu:A, 6lkx:B
12 8dr0:D 344 78 0.0448 0.0581 0.2564 0.48 8dqw:D, 8dqx:D, 8dqz:D, 8dr1:D, 8dr3:D, 8dr4:D, 8dr5:D, 8dr6:D, 8dr7:D, 8fs3:D, 8fs4:D, 8fs5:D, 8fs6:D, 8fs7:D, 8fs8:D, 7sgz:D, 7sh2:D, 7st9:D, 7stb:D, 7ste:D, 1sxj:D, 7tfh:D, 7tfi:D, 7tfj:D, 7tfk:D, 7tfl:D, 7thj:D, 7thv:D, 8thb:D, 8thc:D, 8thd:D, 7ti8:D, 7tib:D, 7tic:D, 7tid:D, 7tku:D, 8tw7:2, 8tw8:2, 8twa:2, 8twb:2, 7u19:D, 7u1a:D, 7u1p:D
13 6ytt:A 708 64 0.0493 0.0311 0.3438 0.72 6ytt:D
14 6kih:A 400 159 0.0852 0.0950 0.2390 1.4 6kih:C, 6kih:D, 6kih:E, 6kih:F, 6kih:H, 6kih:I, 6kih:K, 6kih:L, 6kih:B, 6kih:G, 6kih:J
15 6g59:A 387 166 0.0785 0.0904 0.2108 1.7 6g58:A, 6g58:B, 6g59:B
16 5btr:C 322 105 0.0516 0.0714 0.2190 2.4
17 1ash:A 147 56 0.0426 0.1293 0.3393 6.7
18 7d72:A 407 49 0.0404 0.0442 0.3673 7.2 7d72:B, 7d72:C, 7d72:D, 7d73:A, 7d73:B, 7d73:C, 7d73:D, 7d74:A, 7d74:D, 7d74:B, 7d74:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218