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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ARGPKKHLKRLAAPSHWMLDKLSGTYAPRPSAGPHKLRESLPLVVFLRNRLKYALNGREVKAIMMQQHVQVDGKVRTDTT
YPAGFMDVITLEATNEHFRLVYDVKGKFAVHRISAEEAAYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPLIRANDTVK
IDLATGKIDDFIKFDTGRLVMVTGGRNLGRVGVIVHREKHEGGFDLVHIKDALENTFVTRLSNVFVIGTEAGKPWVSLPK
GKGIKLSISEERDRRRAQQG

The query sequence (length=260) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8c3a:CR 260 260 1.0000 1.0000 1.0000 0.0 8c3a:G, 8cq7:G, 8cq7:CR, 8cqw:G, 8cqw:CR, 8cre:G, 8cre:CR, 8oeq:G, 8oeq:CR, 7pzy:F, 7q08:F, 7q0f:F, 7q0p:F, 7q0r:F, 8q5i:F
2 8bn3:S4 260 260 0.8692 0.8692 0.8692 3.62e-170 7a1g:S, 7ajt:DE, 7aju:DE, 7b7d:S, 8bqd:S, 8bqx:S, 8c00:S, 8c01:S, 8c83:S, 8cah:S, 8cas:S, 8cbj:E, 8ccs:h, 8cdl:h, 8cdr:h, 8ceh:h, 8cf5:h, 8cg8:h, 8cgn:h, 8civ:h, 8cku:h, 8cmj:h, 7d4i:SF, 7d5t:SF, 7d63:SF, 5dat:S4, 5dat:s4, 5dc3:S4, 5dc3:s4, 5dge:S4, 5dge:s4, 5dgf:S4, 5dgf:s4, 5dgv:S4, 5dgv:s4, 6eml:S, 8eub:BE, 8evp:BE, 8evq:BE, 8evr:BE, 8evs:BE, 8evt:BE, 8ewb:BE, 8ewc:BE, 6fai:E, 5fci:S4, 5fci:s4, 5fcj:S4, 5fcj:s4, 6fyx:E, 6fyy:E, 6gq1:u, 6gqb:u, 6gqv:u, 6gsm:E, 6gsn:E, 6hhq:F, 6hhq:s4, 5i4l:S4, 5i4l:s4, 6i7o:Sb, 6i7o:S, 8i7j:E, 5it7:E, 5it9:E, 3j6x:S4, 3j6y:S4, 3j77:S4, 3j78:S4, 3j80:E, 3j81:E, 3jam:E, 3jap:E, 5juo:BB, 5jup:BB, 5jus:BB, 5jut:BB, 5juu:BB, 8k2d:SE, 8k82:SE, 6ke6:SF, 5ll6:S, 6lqp:SF, 6lqq:SF, 6lqr:SF, 6lqs:SF, 6lqt:SF, 6lqu:SF, 6lqv:SF, 5lyb:S4, 5lyb:s4, 5m1j:E2, 5mc6:S, 5mei:s4, 5mei:F, 7mpi:BE, 7mpj:BE, 7n8b:BE, 5ndg:S4, 5ndg:s4, 5ndv:S4, 5ndv:s4, 5ndw:S4, 5ndw:s4, 7nrc:SS, 7nrd:SS, 5obm:S4, 5obm:s4, 5on6:s4, 5on6:F, 7osa:eS4, 7osm:eS4, 6q8y:S, 6rbd:E, 6rbe:E, 7rr5:SE, 8rw1:E, 6s47:BF, 8s8d:E, 8s8e:E, 8s8f:E, 8s8g:E, 8s8h:E, 8s8i:E, 8s8j:E, 6snt:E, 7suk:L4, 6sv4:Sb, 6sv4:S, 6sv4:Sc, 6t4q:SE, 6t7i:SE, 6t7t:SE, 6t83:Eb, 6t83:f, 5tbw:F, 5tbw:s4, 6tb3:S, 5tga:S4, 5tga:s4, 5tgm:S4, 5tgm:s4, 6tnu:S, 5tzs:5, 4u3m:S4, 4u3m:s4, 4u3n:S4, 4u3n:s4, 4u3u:S4, 4u3u:s4, 4u4n:S4, 4u4n:s4, 4u4o:S4, 4u4o:s4, 4u4q:S4, 4u4q:s4, 4u4r:S4, 4u4r:s4, 4u4u:S4, 4u4u:s4, 4u4y:S4, 4u4y:s4, 4u4z:S4, 4u4z:s4, 4u50:S4, 4u50:s4, 4u51:S4, 4u51:s4, 4u52:S4, 4u52:s4, 4u53:S4, 4u53:s4, 4u55:S4, 4u55:s4, 4u56:S4, 4u56:s4, 4u6f:S4, 4u6f:s4, 4uer:W, 6uz7:E, 4v6i:AD, 4v88:AE, 4v88:CE, 4v8y:AE, 4v8z:AE, 4v92:BE, 6wdr:E, 5wlc:L4, 6woo:EE, 7wtl:SE, 7wtm:SE, 7wtn:SE, 7wto:SE, 7wtp:SE, 7wtq:SE, 7wtr:SE, 5wyj:SF, 5wyk:SF, 6xiq:u, 6xir:u, 8y0u:SE, 6y7c:E, 6z6j:SE, 6z6k:SE, 6zce:F, 7zpq:AE, 6zqb:DE, 6zqc:DE, 6zqd:DE, 6zqe:DE, 6zqf:DE, 6zqg:DE, 7zrs:AE, 6zu9:S, 7zuw:AE, 7zux:DE, 6zvi:m, 7zw0:sS
3 7olc:SE 261 254 0.7538 0.7510 0.7717 6.80e-150 7old:SE, 8oo0:SE, 5oql:m, 7r81:F2, 6rxu:Cb, 6rxv:Cb, 6rxx:Cb, 6rxz:Cb, 7z3n:SE, 7z3o:SE
4 4v6w:AE 261 259 0.7346 0.7318 0.7375 2.33e-144 6xu6:AE, 6xu7:AE, 6xu8:AE
5 6fec:I 263 259 0.6923 0.6844 0.6950 1.29e-140 7a01:j3, 7a09:q, 5a2q:E, 5aj0:BE, 9bdl:AS04, 9bdn:AS04, 9bdp:AS04, 8bhf:F3, 9bkd:C, 9bln:C, 8btk:Ad, 7cpu:SE, 7cpv:SE, 4d5l:E, 4d61:E, 6d90:FF, 6d9j:FF, 9f1b:Ad, 9f1c:Ad, 9f1d:Ad, 5flx:E, 6g18:E, 6g4s:E, 6g4w:E, 6g51:E, 6g53:E, 6g5h:E, 6g5i:E, 8g5y:SE, 8g5z:SE, 8g60:SE, 8g61:SE, 8g6j:SE, 8glp:SE, 6gz3:BE, 6gz4:BE, 6gz5:BE, 6hcf:F1, 6hcj:F2, 6hcm:F1, 6hcq:F2, 8ifd:2q, 8ife:2q, 6ip5:2q, 6ip6:2q, 6ip8:2q, 3j7p:SE, 3j7r:SE, 3jag:EE, 3jah:EE, 3jai:EE, 3jaj:SE, 3jan:SE, 8jdj:1, 8jdk:1, 8jdl:1, 8jdm:1, 7jqb:M, 7jqc:M, 5k0y:I, 8k2c:SE, 7k5i:E, 4kzx:E, 4kzy:E, 4kzz:E, 5lks:SE, 7ls1:r2, 7ls2:r2, 5lzs:EE, 5lzt:EE, 5lzu:EE, 5lzv:EE, 5lzw:EE, 5lzx:EE, 5lzy:EE, 5lzz:EE, 7mdz:EE, 7mq8:L4, 7mq9:L4, 7mqa:L4, 6mtb:EE, 6mtc:EE, 6mtd:EE, 6mte:EE, 7nwg:F2, 7nwh:EE, 7nwi:EE, 7o7y:Ad, 7o7z:Ad, 7o80:Ad, 7o81:Ad, 5oa3:E, 6ole:SE, 6olf:SE, 6olg:BE, 6oli:SE, 6olz:BE, 6om0:SE, 6om7:SE, 7oya:E2, 7oyb:E2, 7oyc:E2, 7oyd:EE, 8oz0:Y, 8p03:G, 8p09:G, 8p2k:Ad, 6p4g:F, 6p4h:F, 6p5i:F, 6p5j:F, 6p5k:F, 6p5n:F, 8pj1:C, 8pj2:C, 8pj3:C, 8pj4:C, 8pj5:C, 8pj6:C, 8ppk:E, 8ppl:AE, 8q7z:Ad, 8q87:Ad, 7qgg:SE, 8qoi:SE, 7qp6:C, 7qp7:C, 7qvp:RE, 7qvp:SE, 6qzp:SE, 7r4x:E, 6r5q:x, 6r6g:x, 6r6p:x, 6r7q:x, 8scb:EE, 6sgc:F1, 7syg:F, 7syh:F, 7syi:F, 7syj:F, 7syk:F, 7syl:F, 7sym:F, 7syn:F, 7syo:F, 7syp:F, 7syq:F, 7syr:F, 7sys:F, 7syt:F, 7syu:F, 7syv:F, 7syw:F, 7syx:F, 5t2c:Ar, 8t4s:E, 7toq:AS04, 7tor:AS04, 7tql:E, 7ucj:EE, 7uck:EE, 4ug0:SE, 4ujc:CE, 4ujd:CE, 4uje:BE, 4v6x:AE, 5vyc:E1, 5vyc:E2, 5vyc:E3, 5vyc:E4, 5vyc:E5, 5vyc:E6, 6w2s:F, 6w2t:F, 7wts:E, 7wtt:E, 7wtu:E, 7wtv:E, 7wtw:E, 7wtx:E, 7wtz:E, 7wu0:E, 6xa1:SE, 7xnx:SE, 7xny:SE, 8xsx:SE, 8xsy:SE, 8xsz:SE, 8xxl:SE, 8xxm:SE, 8xxn:SE, 6y0g:SE, 8y0w:SE, 8y0x:SE, 6y2l:SE, 6y57:SE, 6yal:G, 6yam:G, 6yan:G, 6ybw:C, 8yoo:SE, 8yop:SE, 6z6l:SE, 6z6m:SE, 6z6n:SE, 7zjw:SP, 7zjx:SP, 6zlw:E, 6zm7:SE, 6zme:SE, 6zmi:SE, 6zmo:SE, 6zmt:E, 6zmw:C, 6zn5:E, 6zoj:E, 6zok:E, 6zon:q, 6zp4:q, 6zuo:E, 6zv6:E, 6zvh:E, 6zvj:q, 6zvk:j3, 6zxd:E, 6zxe:E, 6zxf:E, 6zxg:E, 6zxh:E
6 7qix:G 261 259 0.6692 0.6667 0.6718 5.11e-129 7qiz:w
7 8jiw:BE 263 255 0.6538 0.6464 0.6667 3.30e-128 8auv:A, 8b2l:A1, 8ip8:ja, 8ip9:ja, 8ipa:ja, 8ipb:ja, 8r6f:E, 4v3p:SD, 4v7e:BE
8 5xxu:E 259 253 0.6346 0.6371 0.6522 1.77e-121
9 9bh5:AE 255 254 0.6154 0.6275 0.6299 2.05e-115 9cai:AE
10 6zj3:SE 265 260 0.5923 0.5811 0.5923 2.70e-114
11 3j7a:F 257 255 0.5692 0.5759 0.5804 3.35e-105 3jbn:F, 3jbo:F, 3jbp:F, 6okk:F, 8tpu:SF
12 4bts:AW 259 257 0.5346 0.5367 0.5409 1.66e-101 4bts:BW, 4bts:CW, 4bts:DW, 5jpq:p, 4v5o:AW, 4v5o:BW
13 8br8:SE 260 255 0.5154 0.5154 0.5255 6.84e-97 8brm:SE, 8bsi:SE, 8bsj:SE, 8btd:SE, 8btr:SE, 8fvy:E, 8g4s:E, 7pwf:E, 7pwo:E1
14 8ova:A1 262 251 0.4962 0.4924 0.5139 2.63e-89 8ove:A1, 4v8m:A1
15 5xyi:E 246 247 0.5000 0.5285 0.5263 4.57e-89
16 6zu5:SE0 257 253 0.4654 0.4708 0.4783 1.64e-88
17 7ase:l 258 251 0.4808 0.4845 0.4980 2.28e-86 5opt:L
18 8a3w:SE 260 251 0.4923 0.4923 0.5100 2.56e-85 8a98:SE, 6az1:E, 8ovj:SE, 8rxh:SE, 8rxx:SE, 5t2a:1
19 8p5d:SE0 260 251 0.4308 0.4308 0.4462 5.59e-78 8p60:SE0, 8p60:RE0, 7qca:SE0
20 7qep:S4 259 258 0.3923 0.3938 0.3953 8.44e-63
21 6rm3:SE0 256 256 0.3846 0.3906 0.3906 1.97e-61
22 6skg:Af 242 243 0.3385 0.3636 0.3621 1.86e-43 6skf:Af, 6th6:Af
23 6sw9:E 242 244 0.3423 0.3678 0.3648 2.25e-43 5jb3:E, 5jbh:E, 6swc:E, 6swd:E, 4v4n:BE, 4v6u:AE, 7zag:E, 7zah:E, 7zai:E, 7zhg:E
24 6tmf:F 241 243 0.3346 0.3610 0.3580 2.07e-41
25 8hkx:AS4E 240 233 0.3038 0.3292 0.3391 6.18e-28 8hky:AS4E, 8hkz:AS4E, 8hl1:AS4E, 8hl2:AS4E, 8hl3:AS4E, 8hl4:AS4E, 8hl5:AS4E, 8wkp:AS4E, 8wq2:AS4E, 8wq4:AS4E
26 2ak5:B 64 51 0.0577 0.2344 0.2941 0.72 2df6:A, 2df6:B
27 7uny:C 127 74 0.0885 0.1811 0.3108 1.1 7uny:B
28 6ttd:A 457 87 0.0885 0.0503 0.2644 3.5 6syy:A, 6ttd:B
29 2agd:A 273 38 0.0654 0.0623 0.4474 4.9 2ae7:A, 2ae7:B, 2ae7:C, 2aec:A, 2aec:B, 2aec:C, 2aes:A, 2aes:B, 2aes:C, 2agd:B, 2agd:C, 2ah9:A, 2ah9:B, 2ah9:C, 3ee5:A, 3ee5:B, 3ee5:C, 4ee3:A, 4ee3:B, 4ee3:C, 4ee4:A, 4ee4:B, 4ee4:C, 4ee5:A, 4ee5:B, 4ee5:C, 4eea:A, 4eea:B, 4eea:C, 4eeg:A, 4eeg:B, 4eeg:C, 4eem:A, 4eem:B, 4eem:C, 4eeo:A, 4eeo:B, 4eeo:C, 2fya:A, 2fyb:A, 2fyc:B, 2fyc:D, 4krv:A, 4krv:B, 1o0r:A, 1o0r:B, 1tvy:A, 1tvy:B, 1tw1:A, 1tw1:B, 1tw5:A, 1tw5:B
30 4tsh:A 121 34 0.0462 0.0992 0.3529 6.4
31 2djy:A 42 23 0.0385 0.2381 0.4348 8.3

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218