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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AQVTCVWDLKATLGEGPIWHGDTLWFVDIKQRKIHNYHPATGERFSFDAPDQVTFLAPIVGATGFVVGLKTGIHRFHPAT
GFSLLLEVEDAALNNRPNDATVDAQGRLWFGTMHDGEENNSGSLYRMDLTGVARMDRDICITNGPCVSPDGKTFYHTDTL
EKTIYAFDLAEDGLLSNKRVFVQFALGDDVYPDGSVVDSEGYLWTALWGGFGAVRFSPQGDAVTRIELPAPNVTKPCFGG
PDLKTLYFTTARKGLSDETLAQYPLAGGVFAVPVDVAGQPQHEVRLV

The query sequence (length=287) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7plb:B 289 287 1.0000 0.9931 1.0000 0.0 7plb:A, 7plc:A, 7plc:D, 7plc:B, 7plc:C, 7pld:A, 7pld:B
2 4gn7:A 297 284 0.3345 0.3232 0.3380 8.01e-38 4gn7:B, 4gn8:A, 4gn8:B, 4gn9:A, 4gn9:B, 4gna:A, 4gna:B
3 4gnc:A 298 284 0.3136 0.3020 0.3169 3.07e-35 3g4e:A, 3g4e:B, 3g4h:B, 3g4h:A, 4gnb:A, 4gnb:B, 4gnc:B
4 5d9b:A 307 282 0.3275 0.3062 0.3333 2.18e-34 5d9c:A, 5d9d:A, 5gtq:A, 5gx1:A, 5gx2:A, 5gx3:A, 5gx4:A, 5gx5:A, 5xfe:A
5 7riz:A 306 169 0.1638 0.1536 0.2781 4.87e-08 8djf:A, 8djz:A, 8dk0:A, 7ris:A
6 3dr2:A 299 170 0.1847 0.1773 0.3118 1.67e-07 3dr2:B
7 3e5z:A 290 217 0.1916 0.1897 0.2535 2.27e-07 3e5z:B
8 2dso:C 323 146 0.1185 0.1053 0.2329 2.38e-06 2dg1:A, 2dg1:B, 2dg1:C, 2dg1:D, 2dg1:E, 2dg1:F, 2dso:A, 2dso:B, 2dso:D, 2dso:E, 2dso:F
9 3o4p:A 314 168 0.1498 0.1369 0.2560 0.032 3byc:A, 1e1a:A, 2gvu:A, 2gvv:A, 2gvw:A, 2gvx:A, 3hlh:A, 3hlh:B, 3hlh:C, 3hlh:D, 3hli:A, 3hli:B, 3hli:C, 3hli:D, 2iao:A, 2iap:A, 2iaq:A, 2iar:A, 2ias:A, 2iat:A, 2iau:A, 2iav:A, 2iaw:A, 2iax:A, 3kgg:A, 3li3:A, 3li4:A, 3li5:A, 1pjx:A
10 6j6g:m 119 64 0.0662 0.1597 0.2969 0.33 7b9v:l, 7b9v:h, 6j6g:z, 6j6h:m, 6j6h:z, 6j6n:m, 6j6n:z, 6j6q:m, 6j6q:z, 6n7p:L, 6n7r:L, 6n7x:L, 8w2o:L, 5zwn:b
11 3k4x:A 758 126 0.1115 0.0422 0.2540 1.0 6e49:B, 6e49:A, 2od8:A, 3v62:B, 3v62:E, 5zut:A
12 7wdq:A 336 63 0.0662 0.0565 0.3016 1.5 7wdq:B, 7wdq:C, 7wdw:A, 7wdw:B, 7wdw:C, 7wdw:D
13 6h0a:A 339 89 0.0906 0.0767 0.2921 1.7 6g82:A, 6gmu:A, 4hho:A, 4hhq:A, 4q1u:A, 3sre:A, 3srg:A, 1v04:A
14 5d76:B 232 72 0.0557 0.0690 0.2222 2.6 5d76:A
15 7agj:A 731 27 0.0418 0.0164 0.4444 2.7 7agj:B
16 7akq:A 389 49 0.0523 0.0386 0.3061 5.8 6epb:A, 6ylj:A, 6yn4:A
17 3sso:B 394 156 0.1463 0.1066 0.2692 7.1 3ssm:A, 3ssm:C, 3ssm:D, 3ssn:A, 3ssn:D, 3ssn:C, 3sso:A, 3sso:C, 3sso:D, 3sso:E, 3sso:F
18 6sk7:C 214 19 0.0383 0.0514 0.5789 8.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218