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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
APYLPLASDHRNGEVQTASNAWLEVDLGAFEHNIQTLKDRLGDKGPKICAIMKADAYGHGIDLLVPSVVKAGIPCIGIAS
NEEARVAREKGFTGRLMRVRAATPAEVEQALPYKMEELIGSLVSAQGIADIAQRHHTNIPVHIALNSAGMSRNGIDLRLA
DSKEDALAMLKLKGITPVGIMTHFPVEEKEDVKMGLAQFKLDSQWLLEAGKLDRSKITIHAANSFATLEVPDAYFDMVRP
GGLLYGDSIPSYTEYKRVMAFKTQVASVNHYPAGNTVGYDRTFTLKRDSWLANLPLGYSDGYRRALSNKAYVLIQGQKVP
VVGKTSMNTIMVDVTDLKGVKPGDEVVLFGRQGEAEVKQADLEEYNGALLADMYTIWGYTNPKKIKRSSGHHHHHH

The query sequence (length=396) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4bf5:A 396 396 1.0000 1.0000 1.0000 0.0 4bf5:B
2 4fs9:A 384 380 0.5505 0.5677 0.5737 7.34e-164 4fs9:B
3 4beu:A 392 377 0.4874 0.4923 0.5119 1.10e-142 7agz:A, 7agz:B, 4beq:A
4 4y2w:A 388 343 0.2854 0.2912 0.3294 3.59e-56 4y2w:B
5 5yyc:A 368 338 0.2525 0.2717 0.2959 4.37e-39 5yyc:C
6 6scz:A 373 365 0.2879 0.3056 0.3123 1.35e-38 8b8h:A, 8b8h:B, 6scz:B, 1xfc:A, 1xfc:B
7 5irp:A 386 363 0.2576 0.2642 0.2810 1.10e-37 5irp:B, 6q70:A, 6q70:B, 6q71:A, 6q71:B, 6q72:A, 6q72:B, 6q72:D, 6q72:E
8 4lut:A 375 363 0.2803 0.2960 0.3058 5.15e-37 4lus:B, 4lut:B
9 1epv:A 382 376 0.2601 0.2696 0.2739 1.05e-35 1bd0:A, 1bd0:B, 1epv:B, 1ftx:A, 1ftx:B, 1l6f:A, 1l6f:B, 1l6g:A, 1l6g:B, 1niu:A, 1niu:B, 1sft:A, 1sft:B, 2sfp:A, 2sfp:B, 1xqk:A, 1xqk:B, 1xql:A, 1xql:B
10 2vd8:A 387 386 0.2753 0.2817 0.2824 1.06e-32 2vd8:B, 2vd9:A, 2vd9:B
11 7xll:A 378 348 0.2475 0.2593 0.2816 2.36e-31 7xll:B
12 5fag:A 390 377 0.2702 0.2744 0.2838 7.33e-30 5fac:A, 5fac:B, 5fac:C, 5fac:D, 5fag:B, 5fag:C, 5fag:D, 5faj:A, 5faj:B, 5faj:C, 5faj:D
13 3b8t:A 359 329 0.2475 0.2730 0.2979 1.03e-26 3b8t:B, 3b8t:C, 3b8t:D, 3b8u:A, 3b8u:B, 3b8u:C, 3b8u:D, 3b8v:A, 3b8v:B, 3b8v:C, 3b8v:D, 3b8w:A, 3b8w:B, 3b8w:C, 3b8w:D, 2rjg:A, 2rjg:B, 2rjg:C, 2rjg:D, 2rjh:A, 2rjh:B, 2rjh:C, 2rjh:D, 4wr3:A, 4wr3:B, 4wr3:C, 4wr3:D, 4xbj:A, 4xbj:B, 4xbj:C, 4xbj:D
14 1vfs:A 383 376 0.2551 0.2637 0.2686 4.67e-25 1vfh:A, 1vfs:B, 1vft:A, 1vft:B
15 6g59:A 387 344 0.2222 0.2274 0.2558 2.81e-24 6g58:A, 6g58:B, 6g59:B
16 6a2f:A 358 335 0.2399 0.2654 0.2836 3.88e-24 6a2f:B
17 1rcq:A 357 340 0.2449 0.2717 0.2853 6.18e-24
18 3e5p:B 371 341 0.2247 0.2399 0.2610 2.20e-23 3e5p:A, 3e5p:C, 3e6e:A, 3e6e:C, 3e6e:B
19 2dy3:D 344 333 0.2298 0.2645 0.2733 3.16e-22 2dy3:A, 2dy3:B, 2dy3:C
20 4a3q:A 356 338 0.2096 0.2331 0.2456 8.70e-20 4a3q:B
21 5zl6:A 372 363 0.2424 0.2581 0.2645 2.89e-19 5zl6:B, 5zl6:C, 5zl6:D
22 3co8:A 360 360 0.2247 0.2472 0.2472 1.75e-17 3co8:B
23 1s4d:E 265 61 0.0556 0.0830 0.3607 0.30 1s4d:A, 1s4d:B, 1s4d:D, 1s4d:F, 1s4d:G, 1s4d:H, 1s4d:I, 1s4d:J, 1s4d:K, 1s4d:L, 1s4d:M
24 6lt4:A 623 126 0.0783 0.0498 0.2460 0.73 6lt4:B, 6lt4:C, 6lt4:D, 6lt4:E, 6lt4:F, 6lt4:G, 6lt4:H, 6lt4:I, 6lt4:J, 6lt4:K, 6lt4:L, 6lt4:M, 6lt4:N
25 3sgi:A 408 80 0.0556 0.0539 0.2750 1.2 7k72:A, 7k72:B, 7k72:C, 7k72:D, 6kdu:A, 6kjm:A, 6kkv:A, 6krh:A, 6ksc:A, 6ksd:A, 6lw8:A, 1zau:A
26 2qua:A 615 38 0.0328 0.0211 0.3421 3.2 2qub:A, 2qub:C, 2qub:E, 2qub:G, 2qub:I, 2qub:K
27 7abr:F 536 110 0.0732 0.0541 0.2636 3.4
28 3a6z:C 616 38 0.0303 0.0195 0.3158 7.2 3a6z:A, 3a70:A, 3a70:C, 2z8x:A, 2z8z:A, 2zj6:A, 2zj7:A, 2zvd:A, 2zvd:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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