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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
APSPEEKLHLITRNLQEVLGEEKLKEILKERELKIYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNM
KAPWELLELRVSYYENVIKAMLESIGVPLEKLKFIKGTDYQLSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPLLSG
LLYPGLQALDEEYLKVDAQFGGIDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTGSKIDLLDRKEDVKKKLKKAFCEP
GNVENNGVLSFIKHVLFPLKSEFVILRDEKWGGNKTYTAYVDLEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKFNTPA
LKKLASAAYP

The query sequence (length=330) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7rou:A 335 334 1.0000 0.9851 0.9880 0.0 1q11:A, 4q93:A, 4qbt:A, 5thh:A
2 2dlc:X 339 338 0.5848 0.5693 0.5710 2.82e-141
3 2cyb:A 319 321 0.3667 0.3793 0.3769 4.71e-69 2cyb:B
4 4nx2:A 313 322 0.3333 0.3514 0.3416 3.57e-51 2ag6:A, 7ckg:B, 3d6u:A, 3d6v:A, 2hgz:A, 4hjx:A, 4hjx:B, 4hpw:A, 1j1u:A, 5l7p:B, 3n2y:A, 3n2y:B, 5n5u:A, 4nda:A, 5nsf:B, 5nsf:A, 5nsf:C, 5nsf:D, 4pbr:A, 4pbs:A, 4pbt:A, 2pxh:A, 3qe4:A, 3qe4:B, 6wrk:A, 6wrn:A, 6wrq:A, 6wrt:A, 7ynw:A, 7ynw:B, 1zh0:A, 1zh6:A, 2zp1:A
5 7ror:B 362 313 0.3091 0.2818 0.3259 7.39e-38 7ror:A, 7ros:A, 7ros:B, 7rot:A, 7rot:B, 3vgj:A, 3vgj:B
6 7sc6:A 349 338 0.3121 0.2951 0.3047 7.14e-34 7scq:A, 7scq:B
7 2cyc:A 371 355 0.3000 0.2668 0.2789 1.16e-30 2cyc:B
8 3p0j:A 657 352 0.2727 0.1370 0.2557 5.62e-18 3p0h:B, 3p0i:B, 3p0j:B
9 3p0j:A 657 89 0.1030 0.0518 0.3820 3.76e-06 3p0h:B, 3p0i:B, 3p0j:B
10 5usf:A 682 353 0.2697 0.1305 0.2521 1.29e-17 3p0h:A, 3p0i:A, 3p0j:C, 3p0j:D, 5usf:B
11 5usf:A 682 89 0.1030 0.0499 0.3820 4.20e-06 3p0h:A, 3p0i:A, 3p0j:C, 3p0j:D, 5usf:B
12 2j5b:A 321 332 0.2455 0.2523 0.2440 5.05e-15 2j5b:B
13 1h3e:A 427 240 0.2030 0.1569 0.2792 3.32e-09
14 1h3f:B 406 233 0.1970 0.1601 0.2790 2.37e-08 1h3f:A
15 6bqz:A 215 188 0.1576 0.2419 0.2766 4.19e-07 6bqz:B
16 2a4m:C 331 270 0.1818 0.1813 0.2222 4.94e-04 1yi8:C, 1yia:B, 1yid:B
17 3jxe:B 363 225 0.1333 0.1212 0.1956 0.11 3jxe:A
18 4jfa:C 348 75 0.0636 0.0603 0.2800 0.20
19 5h4r:A 375 102 0.0758 0.0667 0.2451 0.25
20 4nl8:A 549 46 0.0606 0.0364 0.4348 1.3
21 7q3s:A 453 30 0.0394 0.0287 0.4333 1.4
22 4liq:E 469 77 0.0545 0.0384 0.2338 1.7
23 3fvd:B 367 64 0.0545 0.0490 0.2812 3.2 3fvd:A
24 8a5a:U 690 47 0.0485 0.0232 0.3404 5.7 8a5o:U, 4am7:A, 4am7:B
25 4s28:A 520 98 0.0818 0.0519 0.2755 8.5 4n7q:A, 4s25:A, 4s26:A, 4s26:B, 4s27:A, 4s29:A
26 2g36:A 322 278 0.1879 0.1925 0.2230 9.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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