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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
APPLWRPGRVLARLREHQPGPVHIIDPFKVPVTEAVEKAAELTRLGFAAVLLASTDYESFESHMEPYVAAVKAATPLPVV
LHFPPRPGAGFPVVRGADALLLPALLGSGDDYFVWKSFLETLAAFPGRIPREEWPELLLTVALTFGEDPRTGDLLGTVPV
STASTEEIDRYLHVARAFGFHMVYLYSRNEHVPPEVVRHFRKGLGPDQVLFVSGNVRSGRQVTEYLDSGADYVGFAGALE
QPDWRSALAEIAGR

The query sequence (length=254) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3vkb:B 254 254 1.0000 1.0000 1.0000 0.0 3vk5:A, 3vk5:B, 3vka:A, 3vka:B, 3vkb:A, 3vkc:A, 3vkc:B, 3vkd:A, 3vkd:B
2 4mm1:A 238 226 0.2638 0.2815 0.2965 6.29e-08 4mm1:B, 4mm1:C, 4mm1:D, 4mm1:E, 4mm1:F
3 6jo3:A 247 212 0.2362 0.2429 0.2830 3.96e-07
4 6nke:A 249 252 0.2402 0.2450 0.2421 2.67e-04
5 2wpb:A 302 80 0.1024 0.0861 0.3250 0.053 4bwl:A, 4bwl:B, 4bwl:C, 4bwl:D, 1fdy:A, 1fdy:B, 1fdy:C, 1fdy:D, 1fdz:A, 1fdz:B, 1fdz:C, 1fdz:D, 1hl2:A, 1hl2:B, 1hl2:C, 1hl2:D, 3lbc:D, 3lcw:A, 3lcw:B, 3lcw:C, 3lcw:D, 4uui:A, 4uui:B, 4uui:C, 4uui:D, 2wkj:C, 2wkj:D, 2wpb:B, 2wpb:C, 2wpb:D, 2xfw:A, 2xfw:B, 2xfw:C, 2xfw:D
6 8u8w:A 297 79 0.0984 0.0842 0.3165 0.53
7 5hud:D 457 67 0.0945 0.0525 0.3582 1.1 5huc:A, 5hud:A, 5hud:B, 5hud:C, 5hue:A
8 5epo:A 261 81 0.1024 0.0996 0.3210 1.3 5epo:B, 5epo:C, 5epo:D
9 3oix:A 310 45 0.0630 0.0516 0.3556 2.0 3oix:B, 3oix:C, 3oix:D
10 3qfe:A 305 54 0.0669 0.0557 0.3148 2.1
11 1p4r:A 589 67 0.0591 0.0255 0.2239 2.8 1p4r:B, 1pkx:A, 1pkx:C, 1pl0:A, 1pl0:B, 1pl0:C, 1pl0:D, 5uy8:A, 5uy8:B, 5uy8:C, 5uy8:D, 5uz0:A, 5uz0:B, 5uz0:C, 5uz0:D
12 6zll:A 321 27 0.0354 0.0280 0.3333 4.2 6zl6:A, 6zl6:B, 6zla:A, 6zla:B, 6zla:C, 6zla:D, 6zld:A, 6zld:B, 6zlj:A, 6zlj:B, 6zlk:A, 6zlk:B, 6zlk:C, 6zlk:D, 6zll:B, 6zll:C, 6zll:D
13 2ywc:A 475 45 0.0669 0.0358 0.3778 5.6 2ywc:B, 2ywc:C, 2ywc:D
14 6ucz:B 265 58 0.0669 0.0642 0.2931 5.9 6ucz:A
15 6s6b:K 1024 99 0.1024 0.0254 0.2626 8.8 6s8b:K, 6s8e:K, 6s91:K, 6sh8:K, 6shb:K, 6sic:K
16 5kbk:A 157 24 0.0433 0.0701 0.4583 9.4 5kbl:A, 5kbm:A, 4n3t:A, 4n3u:A
17 3dxy:A 207 67 0.0709 0.0870 0.2687 9.5 3dxz:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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