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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
APLPELLSNNGKHALMVDGAPYIILGSQTNNSSNYPDALKDVWPSMEKMGANTLSIPVAWEQIEPVEGQFDFSFVDVLLK
EARQRKVRLVLLWFATWKNNAPHYAPAWVKLDNARFPRVVKEDGDTLNSLSPLGQNTLAADKKAFVELMKYLAKRDKDHT
VIMVQVQNEVGTYGAVRDYSPMAQAVFNAAVPDDLIQKLQLKPGTWSQVFGRDADEFFHAYQIARYCDEVTVAGKAIKNL
PMYVNVALRNPFNPGLPGQYSSGGGTDNVLHIWKAAAPNIDLIAPDIYFRDYKTVSKVLELYTRPDNALFVAEIGNDQPF
ARYLFPTLGKGGIGFSPFGMDDTDYTNYPLGAKVYNDETIEQFAQVYRLVNPMMREWARLSYQGQVWGVAEPLDSTTEEQ
HKKDRASALTQQLDLGLWDAEVTYGRPMFWVTPPEGNTPAAGGALIAQLDDNEYLVTAYKARVEFKPSQELAGKKFMIER
VEEGRFEKGKWVMERVWNGDQTDWGLNFTDRPHLLRVKMASYSVQ

The query sequence (length=525) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4d1j:D 540 539 1.0000 0.9722 0.9740 0.0 4d1j:A, 4d1j:B, 4d1j:C, 4d1j:E, 4d1j:F, 4d1j:G, 4d1j:H, 5jaw:A, 5jaw:D, 5jaw:B, 5jaw:C, 5jaw:E, 5jaw:F, 5jaw:G, 5jaw:H, 8pej:A, 8pej:B, 8pej:C, 8pej:D, 8pej:E, 8pej:F, 8pej:G, 8pej:H, 6tbf:A, 6tbf:B, 6tbf:C, 6tbf:D, 6tbf:E, 6tbf:F, 6tbf:G, 6tbf:H, 6tbg:A, 6tbg:B, 6tbg:C, 6tbg:D, 6tbg:E, 6tbg:F, 6tbg:G, 6tbg:H, 6tbh:A, 6tbh:C, 6tbh:B, 6tbh:D, 6tbh:E, 6tbh:G, 6tbh:F, 6tbh:H, 6tbi:A, 6tbi:B, 6tbi:C, 6tbi:D, 6tbi:E, 6tbi:F, 6tbi:G, 6tbi:H, 6tbj:A, 6tbj:B, 6tbj:C, 6tbj:D, 6tbj:E, 6tbj:F, 6tbj:G, 6tbj:H, 6tbk:A, 6tbk:B, 6tbk:C, 6tbk:D, 6tbk:E, 6tbk:F, 6tbk:G, 6tbk:H
2 7kmo:A 511 522 0.5638 0.5793 0.5670 0.0
3 6eon:A 754 180 0.0838 0.0584 0.2444 2.03e-04
4 5e9a:B 684 144 0.0724 0.0556 0.2639 8.76e-04 5e9a:A, 5e9a:C, 5e9a:D, 5e9a:E, 5e9a:F
5 3thc:A 605 196 0.0990 0.0860 0.2653 0.002 3thc:B, 3thc:C, 3thc:D, 3thd:A, 3thd:B, 3thd:C, 3thd:D, 3wez:A, 3wez:B, 3wez:C, 3wez:D, 3wf0:A, 3wf0:B, 3wf0:C, 3wf0:D, 3wf1:A, 3wf1:B, 3wf1:C, 3wf1:D, 3wf2:A, 3wf2:B, 3wf2:C, 3wf2:D, 3wf3:A, 3wf3:B, 3wf3:C, 3wf3:D, 3wf4:A, 3wf4:B, 3wf4:C, 3wf4:D
6 5dfa:A 685 160 0.0781 0.0599 0.2562 0.003 5dfa:B, 5dfa:C, 4oif:A, 4oif:B, 4oif:C
7 7vl3:A 707 182 0.0724 0.0537 0.2088 0.003 7vkx:A, 7vkx:B, 7vky:A, 7vky:B, 7vkz:A, 7vkz:B, 7vl0:A, 7vl0:B, 7vl1:A, 7vl1:B, 7vl2:A, 7vl2:B, 7vl3:B, 7vl4:A, 7vl4:B, 7vl5:B, 7vl6:A, 7vl6:B, 7vl7:A, 7vl7:B, 7x87:A, 7x87:B
8 4uzs:A 687 150 0.0762 0.0582 0.2667 0.006 4ucf:A, 4ucf:B, 4ucf:C, 4uzs:B
9 5gsm:A 786 57 0.0419 0.0280 0.3860 0.009 5gsm:B
10 4e8c:A 594 174 0.0762 0.0673 0.2299 0.013 4e8c:B
11 5bxa:A 414 63 0.0362 0.0459 0.3016 0.093
12 8ibt:A 694 150 0.0648 0.0490 0.2267 0.20 8ibs:A, 8ibs:B, 8ibs:C, 8ibs:D, 8ibs:E, 8ibs:F, 8ibt:B
13 3tts:A 675 124 0.0648 0.0504 0.2742 0.20 3tts:B, 3tts:C, 3tts:D, 3tts:E, 3tts:F, 3tty:A, 3tty:B, 3tty:C, 3tty:D, 3tty:E, 3tty:F
14 4fcx:B 369 165 0.0686 0.0976 0.2182 0.30 4fcx:A
15 4uni:A 689 173 0.0800 0.0610 0.2428 0.37 4uni:B, 4uni:C, 4uoz:A, 4uoz:B, 4uoz:C
16 2a1t:C 388 89 0.0476 0.0644 0.2809 0.41 2a1t:A, 2a1t:B, 2a1t:D, 1egc:A, 1egc:B, 1egc:C, 1egc:D, 1egd:A, 1egd:B, 1egd:C, 1egd:D, 1ege:A, 1ege:B, 1ege:C, 1ege:D, 4p13:A, 4p13:B, 4p13:C, 4p13:D, 8sgp:A, 8sgp:B, 8sgp:C, 8sgp:D, 1t9g:A, 1t9g:B, 1t9g:C, 1t9g:D
17 5ljf:A 321 226 0.0933 0.1526 0.2168 1.1 5ljf:B, 4m24:A, 7p6h:A, 7p6h:B, 7p6j:A, 7p6j:B, 7p6j:C, 7p6j:D, 6zz3:A, 6zz3:B, 6zz3:C, 6zz3:D
18 3mdd:A 385 89 0.0457 0.0623 0.2697 2.8 3mdd:B, 3mde:A, 3mde:B, 1udy:A, 1udy:B, 1udy:C, 1udy:D
19 2osx:A 449 65 0.0343 0.0401 0.2769 3.9 2osy:A, 2osy:B, 2oyk:A, 2oyk:B, 2oyl:A, 2oyl:B, 2oym:A, 2oym:B
20 3ahr:A 362 106 0.0514 0.0746 0.2547 4.1 3ahq:A
21 6cpd:B 127 44 0.0248 0.1024 0.2955 4.1 6cpd:A
22 4fbk:A 424 59 0.0305 0.0377 0.2712 4.9 4fbk:B, 4fbq:A, 4fbq:B, 4fbw:A, 4fbw:B
23 6ojz:D 361 127 0.0514 0.0748 0.2126 7.6 6ojx:A, 6ojx:B, 6ojx:C, 6ojz:A, 6ojz:B, 6ojz:C, 6ojz:E, 6ojz:F, 6ok2:A, 6ok2:B, 6ok2:C, 6ok2:D, 6ok2:E, 6ok2:F, 6okv:A, 6okv:B, 6okv:C, 6okv:D, 6okv:E, 6okv:F, 6olm:A, 6olm:B, 6olm:C, 6olm:D, 6olm:E, 6olm:F
24 4khm:A 562 67 0.0362 0.0338 0.2836 8.7 3hkw:A, 3hkw:B, 3hkw:C, 4khm:B, 4khr:A, 6mvo:A, 6mvo:B, 3qgh:A, 3qgi:A, 2xi3:A, 2xi3:B
25 3lbf:A 207 69 0.0381 0.0966 0.2899 9.8 3lbf:B, 3lbf:C, 3lbf:D
26 8ovs:AAA 276 63 0.0400 0.0761 0.3333 9.9 8ovs:BBB

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218