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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
APGAPEGVSALSDAQYNEANKIYFERCAGCHGVLRKGATGKALTPDLTRDLGFDYLQSFITYGSPAGMPNWGTSGELSAE
QVDLMANYLLLDPAAPPEFGMKEMRESWKVHVAPEDRPTQQENDWDLENLFSVTLRDAGQIALIDGATYEIKSVLDTGYA
VHISRLSASGRYLFVIGRDGKVNMIDLWMKEPTTVAEIKIGSEARSIETSKMEGWEDKYAIAGAYWPPQYVIMDGETLEP
KKIQSTRGMTYDEQEYHPEPRVAAILASHYRPEFIVNVKETGKILLVDYTDLDNLKTTEISAERFLHDGGLDGSHRYFIT
AANARNKLVVIDTKEGKLVAIEDTGGQTPHPGRGANFVHPTFGPVWATSHMGDDSVALIGTDPEGHPDNAWKILDSFPAL
GGGSLFIKTHPNSQYLYVDATLNPEAEISGSVAVFDIKAMTGDGSDPEFKTLPIAEWAGITEGQPRVVQGEFNKDGTEVW
FSVWNGKDQESALVVVDDKTLELKHVIKDERLVTPTGKFNVYNTMTDTY

The query sequence (length=529) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1aom:B 559 529 0.9887 0.9356 0.9887 0.0 1aof:A, 1aof:B, 1aom:A, 1aoq:A, 1aoq:B, 1dy7:A, 1dy7:B, 1e2r:A, 1e2r:B, 1gq1:A, 1gq1:B, 1h9x:A, 1h9x:B, 1h9y:A, 1h9y:B, 1hcm:A, 1hcm:B, 1hj3:A, 1hj3:B, 1hj4:A, 1hj4:B, 1hj5:A, 1hj5:B, 1qks:A, 1qks:B
2 1gjq:A 541 527 0.6824 0.6673 0.6850 0.0 1bl9:A, 1bl9:B, 1gjq:B, 5guw:M, 5guw:N, 1hzu:A, 1hzv:A, 1n15:A, 1n15:B, 1n50:A, 1n50:B, 1n90:A, 1n90:B, 1nir:A, 1nir:B, 1nno:A, 1nno:B, 6tpo:A, 6tsi:A, 6tsi:B
3 6rtd:B 466 508 0.2439 0.2768 0.2539 2.72e-27 6rtd:A, 6rte:A, 6rte:B
4 6tp9:A 85 76 0.0454 0.2824 0.3158 7.58e-04 6tp9:C, 6tp9:B, 6tp9:F, 6tp9:D, 6tp9:J, 6tp9:E, 6tp9:K, 6tp9:G, 6tp9:H, 6tp9:I
5 8frn:G 297 51 0.0359 0.0640 0.3725 0.24
6 8frl:G 338 44 0.0321 0.0503 0.3864 0.28 8frm:G, 8fro:G, 8ufg:G, 8ufh:G
7 8snh:G 304 91 0.0548 0.0954 0.3187 0.39
8 6tv9:A 372 366 0.1456 0.2070 0.2104 0.57 6tv9:B, 6tv9:C, 6tv9:D, 6tv9:E, 6tv9:F, 6tv9:G, 6tv9:H
9 5djq:C 303 93 0.0548 0.0957 0.3118 0.61 5djq:M, 5djq:F, 5djq:I, 3mk7:C, 3mk7:M, 3mk7:F, 3mk7:I
10 5djq:C 303 79 0.0435 0.0759 0.2911 4.3 5djq:M, 5djq:F, 5djq:I, 3mk7:C, 3mk7:M, 3mk7:F, 3mk7:I
11 1eil:A 289 61 0.0302 0.0554 0.2623 0.66 1dhy:A, 1eiq:A, 1eir:A, 1kw3:B, 1kw6:B, 1kw8:B, 1kw9:B, 1kwc:B
12 3vh0:A 322 43 0.0302 0.0497 0.3721 0.67 3vh0:D
13 3vh0:A 322 142 0.0662 0.1087 0.2465 3.7 3vh0:D
14 4ueu:A 256 76 0.0491 0.1016 0.3421 0.95 4csv:A
15 2d0w:A 168 27 0.0208 0.0655 0.4074 1.2 2d0w:B
16 3mwb:A 306 45 0.0302 0.0523 0.3556 1.3 3mwb:B
17 3edd:B 597 54 0.0378 0.0335 0.3704 3.2 3edd:A, 3ede:A, 3ede:B, 3edf:A, 3edf:B, 3edj:A, 3edj:B, 3edk:A, 3edk:B, 1h3g:A, 1h3g:B
18 9cd7:A 276 31 0.0265 0.0507 0.4516 3.3 8udv:C
19 6pnx:B 294 31 0.0265 0.0476 0.4516 4.2 9cd7:B, 9cd7:C, 7dhl:A, 4k33:A, 6lvm:A, 6pnx:A, 8udt:A, 8udt:B, 8udt:C, 8udu:A, 8udu:B, 8udv:A, 8udv:B
20 2gc4:D 147 27 0.0208 0.0748 0.4074 4.5 2gc4:H, 2gc4:L, 2gc4:P, 2gc7:D, 2gc7:H, 2gc7:L, 2gc7:P, 1mg2:D, 1mg2:H, 1mg2:L, 1mg2:P, 1mg3:D, 1mg3:H, 1mg3:L, 1mg3:P, 2mta:C
21 1gdv:A 85 87 0.0510 0.3176 0.3103 4.6
22 6bdn:A 307 30 0.0246 0.0423 0.4333 4.7
23 6xkw:p 254 82 0.0359 0.0748 0.2317 6.5 6xkx:p, 6xkz:p
24 3oa8:B 180 82 0.0397 0.1167 0.2561 6.5 3oa8:D, 3oa8:F, 3ocd:B, 3ocd:D
25 5g4l:A 265 45 0.0284 0.0566 0.3333 6.9 5g4l:B
26 8smr:G 312 77 0.0435 0.0737 0.2987 9.3
27 2c1d:A 264 95 0.0435 0.0871 0.2421 9.6 2c1d:C, 2c1d:G, 2c1d:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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