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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
APFGTLLGYAPGGVAIYSSDYVFRSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPL
QAFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQWTRELEMVVENGCYTLKDTFD
DTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYVQANGQVINQDPYHYYTITESAEQ
ELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTE
AGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEENYHAQFMEQALHQAGFETRILRGLDELGW
QLIDGEGRLVNCVWKTWAWETAFDQIREVFAAVPIRTGHPQNEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLFP
HHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDKTSGKFAEQKNIYQQLWCLPKVDGKYIQVCTFTVG
GNYGGTCLRGDESLVIKKESDIEPLIVVK

The query sequence (length=589) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2io9:B 603 603 1.0000 0.9768 0.9768 0.0 3a2y:A, 2io7:A, 2io7:B, 2io8:A, 2io8:B, 2io9:A, 2ioa:A, 2ioa:B, 3o98:A, 3o98:B
2 7uk7:A 389 366 0.1749 0.2648 0.2814 5.34e-29
3 7uka:A 368 372 0.1800 0.2880 0.2849 2.42e-26
4 7olc:A 312 77 0.0323 0.0609 0.2468 0.99 7old:A, 8oo0:A, 7r81:h2, 7z3n:A, 7z3o:A
5 5a2q:g 314 47 0.0255 0.0478 0.3191 1.9 7a01:a3, 7a09:V, 5aj0:Bg, 9bdl:ARAC, 9bdn:ARAC, 9bdp:ARAC, 8bhf:h3, 9bkd:c, 9bln:c, 8btk:AF, 7cpu:Sg, 7cpv:Sg, 4d5l:g, 4d61:g, 6d90:hh, 6d9j:hh, 9f1b:AF, 9f1c:AF, 9f1d:AF, 6fec:m, 5flx:g, 6g18:g, 6g51:g, 6g53:g, 6g5h:g, 6g5i:g, 8g5y:Sg, 8g5z:Sg, 8g60:Sg, 8g61:Sg, 8g6j:Sg, 8glp:Sg, 6gz3:Bg, 6gz4:Bg, 6gz5:Bg, 6hcf:h1, 6hcj:h2, 6hcm:h1, 6hcq:h2, 8ifd:3F, 8ife:3F, 6ip5:3F, 6ip6:3F, 6ip8:3F, 3j7p:Sg, 3j7r:Sg, 3jag:gg, 3jah:gg, 3jai:gg, 3jaj:Sg, 3jan:Sg, 8jdj:AR, 8jdk:AR, 8jdl:AR, 8jdm:AR, 7jqb:h, 7jqc:h, 5k0y:m, 8k2c:Sg, 7k5i:g, 4kzx:g, 4kzy:g, 4kzz:g, 5lks:Sg, 7ls1:I3, 7ls2:I3, 5lzs:gg, 5lzt:gg, 5lzu:gg, 5lzv:gg, 5lzw:gg, 5lzx:gg, 5lzy:gg, 5lzz:gg, 7mdz:gg, 6mtb:gg, 6mtc:gg, 6mtd:gg, 6mte:gg, 7nwg:h2, 7nwh:gg, 7nwi:gg, 7o7y:AF, 7o7z:AF, 7o80:AF, 7o81:AF, 5oa3:g, 6ole:Sg, 6olf:Sg, 6olg:Bg, 6oli:Sg, 6olz:Bg, 6om0:Sg, 6om7:Sg, 7oya:g2, 7oyb:g2, 7oyc:g2, 7oyd:Gg, 8oz0:k, 8p03:g, 8p09:g, 8p2k:AF, 6p4g:h, 6p4h:h, 6p5i:h, 6p5j:h, 6p5k:h, 6p5n:h, 8pj1:c, 8pj2:c, 8pj3:c, 8pj4:c, 8pj5:c, 8pj6:c, 8ppk:g, 8ppl:Ag, 8q7z:AF, 8q87:AF, 7qgg:Sg, 8qoi:Sg, 7qp6:c, 7qp7:c, 7qvp:Sg, 6qzp:Sg, 7r4x:g, 6r5q:6, 6r6g:6, 6r6p:6, 6r7q:6, 8scb:gg, 6sgc:h1, 7syg:h, 7syh:h, 7syi:h, 7syj:h, 7syk:h, 7syl:h, 7sym:h, 7syn:h, 7syo:h, 7syp:h, 7syq:h, 7syr:h, 7sys:h, 7syt:h, 7syu:h, 7syv:h, 7syw:h, 7syx:h, 5t2c:AI, 8t4s:g, 7toq:ARAC, 7tor:ARAC, 7tql:j, 7ucj:Gg, 7uck:Gg, 4ug0:Sg, 4ujc:Cg, 4ujd:Cg, 4uje:Bg, 4v5z:Aa, 4v6x:Ag, 5vyc:g1, 5vyc:g2, 5vyc:g3, 5vyc:g4, 5vyc:g5, 5vyc:g6, 6w2s:h, 6w2t:h, 6xa1:Sg, 7xnx:Sg, 7xny:Sg, 8xsx:Sg, 8xsy:Sg, 8xsz:Sg, 8xxl:Sg, 8xxm:Sg, 8xxn:Sg, 6y0g:Sg, 8y0w:Sg, 8y0x:Sg, 6y2l:Sg, 6yal:g, 6yam:g, 6yan:g, 6ybs:c, 8yoo:Sg, 8yop:Sg, 6z6l:Sg, 6z6m:Sg, 6z6n:Sg, 7zjw:SG, 7zjx:SG, 6zlw:j, 6zm7:Sg, 6zme:Sg, 6zmi:Sg, 6zmo:Sg, 6zmt:j, 6zmw:c, 6zn5:j, 6zoj:g, 6zol:g, 6zon:V, 6zp4:V, 6zuo:g, 6zv6:g, 6zvh:g, 6zvj:V, 6zvk:a3, 6zxd:g, 6zxe:g, 6zxf:g, 6zxg:g, 6zxh:g
6 3h2s:A 216 74 0.0424 0.1157 0.3378 2.3 3h2s:B
7 6wgm:A 304 76 0.0357 0.0691 0.2763 6.9
8 7bkb:G 568 35 0.0221 0.0229 0.3714 7.6 7bkb:g, 7bkc:G, 7bkc:g
9 5znq:A 183 36 0.0289 0.0929 0.4722 7.8 5b6h:A, 5y07:A, 5y07:B, 5zc7:A, 5zc7:B, 5zmi:A, 5znq:B, 5zoc:A
10 2fax:A 138 89 0.0441 0.1884 0.2921 9.3 2fdx:A, 1fla:A, 1fld:A, 1fln:A, 2flv:A, 2fox:A, 1fvx:A, 2fvx:A, 3nll:A, 4nll:A, 5nll:A, 4nul:A, 5nul:A, 6nul:A, 5ull:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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