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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
APAQAFATRVIHAGQAPDPSTGAIMPPIYANSTYIQESPGVHKGLDYGRSHNPTRWALERCVADLEGGTQAFAFASGLAA
ISSVLELLDAGSHIVSGNDLYGGTFRLFERVRRRSAGHRFSFVDPTDLQAFEAALTPETRMVWVETPSNPLLRLTDLRAI
AQLCRARGIISVADNTFASPYIQRPLELGFDVVVHSTTKYLNGHSDVIGGIAIVGDNPDLRERLGFLQNSVGAISGPFDA
FLTLRGVKTLALRMERHCSNALALAQWLERQPQVARVYYPGLASHPQHELAKRQMRGFGGMISLDLRCDLAGARRFLENV
RIFSLAESLGGVESLIEHPAGDSLIRLSVGVEALEDLQADLAQALAKIHH

The query sequence (length=370) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ba4:A 377 387 0.9676 0.9496 0.9251 0.0 7ba4:B, 7ba4:C, 7ba4:D
2 4iyo:D 384 380 0.6541 0.6302 0.6368 0.0 4ixs:B, 4ixz:A, 4iy7:A, 4iy7:B, 4iy7:C, 4iy7:D, 4iyo:A, 4iyo:B, 4iyo:C
3 6k1l:A 382 380 0.6514 0.6309 0.6342 3.11e-180 6k1l:B, 6k1l:C, 6k1l:D, 6k1m:A, 6k1m:B, 6k1m:C, 6k1m:D, 6k1n:A, 6k1n:B, 6k1n:C, 6k1n:D
4 6cja:A 381 377 0.5838 0.5669 0.5729 2.31e-155 6cja:B, 6cja:C, 6cja:D
5 4l0o:H 373 378 0.5027 0.4987 0.4921 1.91e-128 4l0o:A, 4l0o:C, 4l0o:E, 4l0o:G, 4l0o:M, 4l0o:O
6 8j6n:A 390 385 0.5162 0.4897 0.4961 5.17e-126 8j6n:D, 8j6n:B, 8j6n:C, 8j6n:E, 8j6n:H, 8j6n:J, 8j6n:K, 8j6n:F, 8j6n:G, 8j6n:I, 8j6n:L
7 7d7o:B 377 376 0.4865 0.4775 0.4787 9.87e-126 7d7o:A
8 6ldo:A 381 381 0.5000 0.4856 0.4856 1.60e-123 6ldo:B, 6ldo:C, 6ldo:D, 6ldo:E, 6ldo:F, 6le4:A, 6le4:B, 6le4:C, 6le4:D, 6le4:E, 6le4:F
9 5x5h:A 385 382 0.4838 0.4649 0.4686 2.50e-120
10 3cog:D 392 385 0.5135 0.4847 0.4935 4.24e-119 3cog:A, 3cog:B, 3cog:C, 5eig:C, 5eig:D, 5eig:E, 5eig:F, 5eig:G, 6nba:A, 6nba:B, 6nba:C, 6nba:D, 2nmp:A, 2nmp:B, 2nmp:C, 2nmp:D, 5tsu:A, 5tsu:C, 5tsu:D, 5tsu:E, 5tsu:F, 5tsu:G, 5tsu:H
11 3qhx:A 377 376 0.5081 0.4987 0.5000 6.84e-116 3qhx:B
12 7mcb:H 380 376 0.4486 0.4368 0.4415 3.90e-112 7mcl:H, 7mcn:H, 7mcp:A, 7mcp:H, 7mcq:A, 7mcq:H, 7mct:H, 7mcu:H, 7mcy:H, 7md0:H, 7md6:H, 7md8:H, 7mda:H, 7mdb:H
13 6egr:A 396 389 0.4838 0.4520 0.4602 4.28e-108 5d5s:A, 5e4z:A, 4hf8:A, 3jw9:A, 3jwa:A, 3jwb:A, 5k30:A, 5m3z:A, 3mkj:A, 4oma:A, 6s0c:A
14 8jui:A 380 378 0.4459 0.4342 0.4365 7.45e-106
15 1pg8:A 398 386 0.4649 0.4322 0.4456 2.47e-104 7f1u:A, 7f1u:B, 7f1u:C, 7f1u:D, 7f1v:A, 7f1v:B, 7f1v:C, 7f1v:D, 1pg8:C, 1pg8:B, 1pg8:D, 3vk3:A, 3vk3:B, 3vk3:C, 3vk3:D, 5x2w:A, 5x2w:B, 5x2w:C, 5x2w:D, 5x2x:A, 5x2x:B, 5x2x:C, 5x2x:D, 5x2z:A, 5x2z:B, 5x2z:C, 5x2z:D, 5x30:A, 5x30:B, 5x30:C, 5x30:D
16 5dx5:A 399 388 0.4514 0.4185 0.4304 1.89e-102 5dx5:B
17 6ld8:A 388 381 0.4541 0.4330 0.4409 3.14e-100 6ld8:D, 6ld8:B, 6ld8:C, 6ld9:A, 6ld9:B, 6ld9:C, 6ld9:D, 6lgo:A, 6lgo:B, 6lgo:C, 6lgo:D
18 1cs1:D 384 373 0.4432 0.4271 0.4397 7.40e-99
19 1n8p:A 393 390 0.4514 0.4249 0.4282 2.45e-97 1n8p:B, 1n8p:C, 1n8p:D
20 7nl1:D 400 382 0.4108 0.3800 0.3979 2.71e-91 8bis:C, 8bis:A, 8biu:G, 8biu:A, 8biv:A, 8biv:E, 8biw:E, 8biw:A, 8bix:C, 8bix:A, 8biz:E, 8biz:A, 7nl1:A, 7nl1:B, 7nl1:C, 7nl1:E, 7nl1:F, 7nl1:G, 7nl1:H
21 1ibj:A 380 375 0.4000 0.3895 0.3947 3.53e-88 1ibj:C
22 1e5e:A 394 387 0.4054 0.3807 0.3876 1.10e-87 1e5e:B, 1e5f:A, 1e5f:B
23 3aej:A 387 365 0.3784 0.3618 0.3836 4.44e-86 3aej:D, 3aej:B, 3aej:C, 3ael:A, 3ael:D, 3ael:B, 3ael:C, 3aem:A, 3aem:D, 3aem:B, 3aem:C, 3aen:A, 3aen:D, 3aen:B, 3aen:C, 3aeo:A, 3aeo:D, 3aeo:B, 3aeo:C, 3aep:A, 3aep:D, 3aep:B, 3aep:C
24 1qgn:A 398 387 0.3892 0.3618 0.3721 6.15e-77 1i41:A, 1i41:C, 1i41:B, 1i41:D, 1i41:E, 1i41:G, 1i41:F, 1i41:H, 1i41:I, 1i41:K, 1i41:J, 1i41:L, 1i43:A, 1i43:C, 1i43:B, 1i43:D, 1i43:E, 1i43:G, 1i43:F, 1i43:H, 1i43:I, 1i43:K, 1i43:J, 1i43:L, 1i48:A, 1i48:C, 1i48:B, 1i48:D, 1i48:E, 1i48:G, 1i48:F, 1i48:H, 1i48:I, 1i48:K, 1i48:J, 1i48:L, 1qgn:C, 1qgn:B, 1qgn:D, 1qgn:E, 1qgn:G, 1qgn:F, 1qgn:H
25 8wko:A 425 421 0.4054 0.3529 0.3563 2.59e-72 8wko:B, 8wkr:A, 8wkr:B, 8wkr:C, 8wkr:D
26 7kb1:A 428 425 0.3946 0.3411 0.3435 3.18e-70 7kb1:B, 7kb1:C, 7kb1:D
27 2ctz:A 421 420 0.4189 0.3682 0.3690 7.87e-70 2ctz:B
28 8erb:K 429 429 0.3811 0.3287 0.3287 3.60e-58 8erb:A, 8erb:C, 8erb:B, 8erb:D, 8erb:G, 8erb:H, 8erb:F, 8erb:P, 8erb:I, 8erb:J, 8erb:M, 8erb:E, 8erb:Q, 8erb:N, 8erb:L, 8erj:A, 8erj:B, 8erj:C, 8erj:D, 8erj:E, 8erj:F, 8erj:H, 8erj:G
29 5ijg:B 403 394 0.3568 0.3275 0.3350 8.31e-52 5ijg:A
30 1cl1:B 392 390 0.3351 0.3163 0.3179 2.46e-51 1cl1:A, 1cl2:A, 1cl2:B, 2fq6:A, 2fq6:B, 2gqn:A, 2gqn:B, 4itx:A, 4itx:B
31 8ovh:A 400 414 0.3757 0.3475 0.3357 2.64e-48 8ovh:B, 8ovh:C, 8ovh:D
32 2cb1:A 404 405 0.3838 0.3515 0.3506 9.21e-48
33 8sad:A 398 390 0.3243 0.3015 0.3077 1.42e-47 8sa7:A, 8sa7:B, 8sa8:A, 8sa8:D, 8sa8:B, 8sa8:C, 8sa9:A, 8sa9:B, 8saa:A, 8saa:B, 8sab:A, 8sab:B, 8sac:A, 8sac:D, 8sac:B, 8sac:C, 8sad:B, 8sae:A, 8sae:B, 8u98:A, 8u98:D, 8u98:B, 8u98:C, 8u99:A, 8u99:B
34 7yeo:B 382 396 0.3541 0.3429 0.3308 5.04e-41 7yeo:A
35 3lvm:B 394 127 0.0946 0.0888 0.2756 1.62e-04 3lvj:A, 3lvj:B, 3lvk:A, 3lvl:B, 3lvm:A, 1p3w:B, 1p3w:A
36 1v2e:A 368 66 0.0703 0.0707 0.3939 3.02e-04 1v2d:A, 1v2e:B, 1v2f:A, 1v2f:B
37 2r5c:B 419 54 0.0459 0.0406 0.3148 0.001 2r5e:A, 2r5e:B, 1yiy:A, 1yiy:B
38 3e2y:A 410 111 0.0676 0.0610 0.2252 0.12 3e2y:B, 3e2z:A, 3e2z:B, 5vep:A, 5veq:A, 5veq:B, 5ver:A, 5ver:B
39 8wkj:A 391 22 0.0324 0.0307 0.5455 0.14
40 1lc7:A 358 104 0.0919 0.0950 0.3269 0.31 1lc5:A, 1lc8:A, 1lkc:A
41 1j32:A 388 47 0.0432 0.0412 0.3404 0.37 1j32:B
42 3fvs:B 419 58 0.0405 0.0358 0.2586 0.96 3fvu:A, 3fvu:B, 1w7l:A, 1w7m:A, 1w7n:A, 4wlj:A, 4wlj:B
43 1u08:A 382 55 0.0459 0.0445 0.3091 1.2 1u08:B
44 5wgb:A 291 43 0.0378 0.0481 0.3256 1.6
45 6f35:A 400 22 0.0324 0.0300 0.5455 1.8 6f35:B
46 6nzu:A 402 43 0.0378 0.0348 0.3256 1.9 6nzu:E, 8pk8:A, 8pk9:A, 8pka:A, 7rtk:A, 8tvt:A, 6uxe:A, 6w1d:A, 6wi2:A, 6wih:A, 5wkp:A, 5wkp:E, 5wlw:A, 5wlw:E
47 8k3h:A 480 31 0.0405 0.0312 0.4839 2.0 8k3h:B
48 3nu7:B 359 151 0.1054 0.1086 0.2583 2.3 3nu7:A, 3nub:A, 3nub:B, 3nys:A, 3nyt:A
49 3l8a:B 385 214 0.1351 0.1299 0.2336 2.7 3l8a:A
50 1uf9:B 191 36 0.0405 0.0785 0.4167 3.6 1uf9:C
51 1t3i:A 406 119 0.0811 0.0739 0.2521 3.6 1t3i:B
52 4r2n:A 353 106 0.0865 0.0907 0.3019 3.7 4r2n:C, 4r2n:B, 4r2n:D, 4r5z:A, 4r5z:B, 4r5z:C, 4r5z:D
53 2n7c:A 89 40 0.0297 0.1236 0.2750 5.0
54 1wyu:B 473 77 0.0622 0.0486 0.2987 5.7 1wyu:D, 1wyu:F, 1wyu:H, 1wyv:B, 1wyv:D, 1wyv:F, 1wyv:H
55 4cvq:A 404 54 0.0432 0.0396 0.2963 6.0 4cvq:B
56 2qb5:A 338 56 0.0459 0.0503 0.3036 6.1 2q7d:A, 2q7d:B, 2qb5:B
57 2oga:A 371 99 0.0784 0.0782 0.2929 6.3 2oga:B, 2oga:C, 2oga:D
58 4lis:A 364 58 0.0459 0.0467 0.2931 9.6 4lis:B, 4lis:C
59 1ssq:D 257 88 0.0730 0.1051 0.3068 10.0 1ssq:A, 1sst:A, 1sst:B, 1sst:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218