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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
APALAEVLAPTVPWPLSGKNPGALQGQAARLAAHLAEDHDLSLSDLGLSLATTRARLEHRAVVVLGSREEALGGLGALGE
QMPAGNVVTGAADLSGKTVFVFPGQGSQWAGMAVELLDSSPVFAARFAEVAGAVEAYVDWSVESVVRGADEAPSLDRIEI
LQPVLFTVMVSLAALWRAAGVVPDAVVGHCQGEIAAAAVSGALSLGDAAQVVVLRSQLFADELVGKGAVASVSLPAAEVE
ARIARFNGDAELLSIAGNNGPRSVTVAGQVAALEELVAELEAEGVRAKVIGSTVASHSAQVDPLHERILDLLSFVQPREG
SVPLYSTVNGEVLNGAELDASYWFENSRRPVSFEPVVRALFADGFDVFVESSAHPVLTYGISETAEAAGREVLAQGTLRR
EEGGLARFYSSLAGVWTRGVDVDWAGAFAGRGARVVDLPTYAFQ

The query sequence (length=444) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7vrs:A 444 444 1.0000 1.0000 1.0000 0.0 7vrs:B
2 7s6c:B 891 435 0.4595 0.2290 0.4690 3.07e-125
3 2qo3:B 873 437 0.4437 0.2257 0.4508 3.74e-98 2qo3:A
4 7m7f:A 1390 439 0.4640 0.1482 0.4692 1.39e-96 2fr0:A, 2fr1:A, 7m7i:A
5 6l3m:B 420 412 0.4212 0.4452 0.4539 2.06e-88 6l3m:A, 6l3m:C, 6l3m:D, 6l3n:A, 6l3n:B, 6l3n:C, 6l3n:D
6 7ags:A 427 427 0.3378 0.3513 0.3513 2.07e-54 7agu:A
7 7vef:A 828 454 0.3671 0.1969 0.3590 2.89e-44 8in9:A
8 4mz0:A 896 445 0.2658 0.1317 0.2652 1.58e-42
9 8i4y:A 1687 461 0.3559 0.0937 0.3427 6.64e-35 8i4y:B, 8i4z:A
10 3tzw:A 467 439 0.2928 0.2784 0.2961 1.09e-31 3tzx:B, 3tzx:A, 3tzy:B, 3tzy:A, 3tzz:B, 3tzz:A
11 4mz0:B 823 442 0.2410 0.1300 0.2421 6.34e-30
12 8cuy:A 1016 404 0.2523 0.1102 0.2772 9.00e-30
13 5ydl:A 408 367 0.2545 0.2770 0.3079 3.16e-28 5ydm:A
14 8cg6:A 1208 447 0.2658 0.0977 0.2640 6.29e-23
15 8cg5:A 1282 447 0.2658 0.0920 0.2640 9.92e-23 6fij:B
16 3tqe:A 316 276 0.1847 0.2595 0.2971 6.38e-22
17 8aw0:A 320 269 0.1622 0.2250 0.2677 9.04e-21 8avz:A, 8avz:C, 8avz:B, 8avz:D, 8aw0:F, 8aw0:B, 8aw0:D, 8aw0:C, 8aw0:H, 8aw0:E
18 7cpx:A 2262 427 0.2455 0.0482 0.2553 4.49e-18 7cpx:B, 7cpy:A, 7cpy:B
19 6u0j:A 309 290 0.1914 0.2751 0.2931 5.84e-18 2g2z:A
20 3im9:A 313 283 0.1689 0.2396 0.2650 7.34e-18
21 5zk4:A 287 283 0.1802 0.2787 0.2827 3.33e-16 6apg:A, 6apg:B, 3sbm:A, 5zk4:B
22 3hjv:A 307 285 0.1824 0.2638 0.2842 1.72e-14
23 5my0:A 852 338 0.2005 0.1045 0.2633 2.22e-13 5my0:C, 5my0:D, 5my2:D, 6rop:A, 6rop:C, 6rop:D
24 2jfk:D 410 346 0.2140 0.2317 0.2746 7.17e-12
25 2vz9:B 2086 336 0.1937 0.0412 0.2560 4.43e-11 2vz9:A
26 6rop:B 831 188 0.1194 0.0638 0.2819 6.38e-08
27 8csp:8 326 281 0.1486 0.2025 0.2349 6.35e-06 2c2n:A, 8csq:8, 8csr:8, 8css:8
28 4v8l:D 2822 213 0.1351 0.0213 0.2817 0.036 4ce4:o, 6hiv:US, 6hiv:UT, 6hiw:US, 6hiw:UT, 6hiy:US, 6hiy:UT, 4v8l:E, 4v8l:F, 4v8l:A, 4v8l:B, 4v8l:C, 4v8v:A, 4v8v:B, 4v8v:C, 4v8v:D, 4v8v:E, 4v8v:F, 4v8w:D, 4v8w:E, 4v8w:F, 4v8w:A, 4v8w:B, 4v8w:C
29 4amp:A 372 156 0.0946 0.1129 0.2692 0.11
30 7tui:B 2033 37 0.0405 0.0089 0.4865 0.17 6u5v:B, 6u5w:B
31 8h6s:A 306 206 0.1014 0.1471 0.2184 0.23 5czc:A, 5czd:A, 7f2r:A, 7f2r:C, 8h6s:B
32 6gjc:A 2770 264 0.1599 0.0256 0.2689 0.43 6gjc:B, 6gjc:C, 6gjc:D, 6gjc:E, 6gjc:F
33 8ps2:G 2036 35 0.0383 0.0083 0.4857 0.43 3hmj:G, 3hmj:H, 3hmj:I, 8prv:G, 8prw:G, 8prw:J, 8prw:I, 8prw:H, 8prw:K, 8prw:L, 8ps1:G, 8ps9:G, 8psa:G, 8psf:G, 8psg:G, 8psj:G, 8psk:G, 8psl:G, 8psm:G, 8psp:G, 6ql5:I, 6ql5:G, 6ql5:H, 6ql5:L, 6ql5:J, 6ql5:K, 6ql6:G, 6ql6:H, 6ql6:I, 6ql6:J, 6ql6:K, 6ql6:L, 6ql9:G, 6ql9:H, 6ql9:I, 6ql9:J, 6ql9:K, 6ql9:L, 6ta1:G, 6ta1:C, 6ta1:E, 6ta1:L, 6ta1:H, 6ta1:J, 6u5t:G, 6u5u:G, 2uv8:G, 2uv8:H, 2uv8:I, 2vkz:G, 2vkz:H, 2vkz:I
34 7bc4:B 2054 37 0.0383 0.0083 0.4595 0.77
35 5j0n:F 356 114 0.0766 0.0955 0.2982 0.77 5j0n:E, 5j0n:G, 5j0n:H, 1p7d:A, 1p7d:B, 2wcc:3, 1z19:B, 1z19:A, 1z1b:B, 1z1b:A, 1z1g:A, 1z1g:D, 1z1g:B, 1z1g:C
36 4v58:G 2060 25 0.0315 0.0068 0.5600 0.80 4v58:H, 4v58:I, 4v58:J, 4v58:K, 4v58:L, 4v59:G, 4v59:H, 4v59:I, 4v59:J, 4v59:K, 4v59:L
37 6zz6:A 360 95 0.0586 0.0722 0.2737 0.81
38 5zhe:B 200 56 0.0450 0.1000 0.3571 1.5
39 1eso:A 154 64 0.0383 0.1104 0.2656 2.5
40 7syl:W 83 52 0.0338 0.1807 0.2885 3.1 6gz3:BV, 6olz:BV, 6om0:SV, 6om7:SV, 7oyb:V2, 7tor:AS21, 7wtw:V, 7wtz:V
41 2k4w:A 154 53 0.0383 0.1104 0.3208 3.2
42 6sga:F2 915 60 0.0428 0.0208 0.3167 3.5 7pua:F2, 6sgb:F2
43 5agi:A 252 54 0.0383 0.0675 0.3148 5.0 5agj:A, 2wfg:A
44 6stu:A 204 82 0.0450 0.0980 0.2439 6.1 8ofs:A, 8ofs:B, 8ofs:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218