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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
APAERCAHPGADLGAAVHAVGQTLAAGGLVPPDEAGTTARHLVRLAVRYGNSPFTPLEEARHDLGVDRDAFRRLLALFGQ
VPELRTAVETGPAGAYWKNTLLPLEQRGVFDAALARKPVFPYSVGLYPGPTCMFRCHFCVRVTGARYDPSALDAGNAMFR
SVIDEIPAGNPSAMYFSGGLEPLTNPGLGSLAAHATDHGLRPTVYTNSFALTERTLERQPGLWGLHAIRTSLYGLNDEEY
EQTTGKKAAFRRVRENLRRFQQLRAERESPINLGFAYIVLPGRASRLLDLVDFIADLNDAGQGRTIDFVNIREDERAELQ
EALNAFEERVRERTPGLHIDYGYALNSLRTGADAELLRIKPATMRPTAHPQVAVQVDLLGDVYLYREAGFPDLDGATRYI
AGRVTPDTSLTEVVRDFVERGGEVAAVDGDEYFMDGFDQVVTARLNQLERDAADGWEEARGFLRLEHHHHHH

The query sequence (length=472) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8hzv:A 479 477 0.9852 0.9708 0.9748 0.0 8hzv:B, 8hzv:C, 8hzv:D, 8hzy:A, 8hzy:B
2 4v61:BD 227 103 0.0551 0.1145 0.2524 0.025
3 4m7t:A 246 164 0.0826 0.1585 0.2378 0.083
4 6c9a:B 723 62 0.0318 0.0207 0.2419 1.0 6c9a:A
5 8beg:A 650 118 0.0593 0.0431 0.2373 1.2 8beg:B
6 8ytx:F 268 73 0.0466 0.0821 0.3014 1.8 6gze:F, 4o4j:F, 5o7a:F, 7zyw:F
7 4tr0:A 92 42 0.0339 0.1739 0.3810 2.0 4tr0:B, 4tr1:A, 4tr1:B
8 3mbf:A 337 83 0.0487 0.0682 0.2771 2.0 3mbd:A, 3qrh:A
9 7zi4:G 682 46 0.0297 0.0205 0.3043 2.5
10 8b1r:B 1170 152 0.0763 0.0308 0.2368 2.5 3k70:B, 3k70:E, 5ld2:B, 7mr4:B, 1w36:B, 1w36:E
11 8b1t:B 1141 152 0.0763 0.0316 0.2368 2.6 8b1u:B, 7mr3:B, 6sjb:B, 6sje:B, 6sjf:B, 6sjg:B, 6t2u:B, 6t2v:B
12 3cjp:A 262 55 0.0318 0.0573 0.2727 2.9 3cjp:B
13 4m7s:A 214 94 0.0487 0.1075 0.2447 3.6
14 7nf4:A 504 24 0.0254 0.0238 0.5000 3.9 8crd:A, 6ev3:A, 6ev4:A, 6ev5:A, 6ev6:A, 6ev7:A, 6ev8:A, 6ev9:A, 6eva:A, 6evb:A, 6evc:A, 6evd:A, 7nf3:A, 7nf4:B, 8oed:A, 8oeh:A, 8oeo:A, 6r2p:A, 6r2r:A, 6r2t:A, 6r2z:A, 6r30:A, 6r32:A, 6r33:A, 6r34:A, 6r3f:A, 6r3g:A, 6r3i:A, 6r3j:A, 6r3l:A, 6r3n:A, 6r3o:A, 6tib:AAA, 6tic:AAA, 6tie:AAA, 6tih:AAA, 6tij:AAA, 6til:AAA, 6tin:AAA, 6tio:AAA, 4za4:A, 4za5:A, 4za7:A, 4za8:A, 4za9:A, 4zaa:A, 4zab:A
15 1sp8:D 393 60 0.0381 0.0458 0.3000 4.1 1sp8:A, 1sp8:B, 1sp8:C, 7x7l:A, 7x7l:B, 7x7l:C, 7x7l:D
16 8hkb:A 302 104 0.0572 0.0894 0.2596 4.3 8hka:A
17 8wev:A 486 22 0.0297 0.0288 0.6364 4.6 8wev:B
18 7me2:A 281 13 0.0212 0.0356 0.7692 5.1 7me1:A, 7me1:B, 7me2:B, 7me3:A, 7me3:B, 6q1d:A, 5uxs:A, 5uxu:A, 5uy0:A, 5uy4:A, 5uy5:A, 5uya:A, 5uyb:A, 5uyc:A, 5uyd:A, 5uye:A, 5uyf:A, 5uyg:A, 5uyh:A, 5uyv:A, 5uyw:A
19 6ln4:A 218 39 0.0233 0.0505 0.2821 5.5 6lit:A, 6lit:B
20 7vob:C 327 59 0.0466 0.0673 0.3729 5.9 7voc:C
21 2fe3:B 143 95 0.0551 0.1818 0.2737 6.0 3f8n:A, 3f8n:B, 2fe3:A, 2rgv:A, 2rgv:B
22 7p61:F 442 75 0.0487 0.0520 0.3067 6.0 7awt:F, 7nyr:F, 7nyu:F, 7nyv:F, 7nz1:F, 7p62:F, 7p63:F, 7p64:F, 7p69:F, 7p7c:F, 7p7e:F, 7p7j:F, 7p7k:F, 7p7l:F, 7p7m:F, 7z7r:F, 7z7s:F, 7z7t:F, 7z7v:F, 7z80:F, 7z83:F, 7z84:F, 7zc5:F, 7zci:F
23 5v1q:B 440 98 0.0466 0.0500 0.2245 6.1 5v1q:A, 5v1s:A, 5v1s:B, 5v1t:A
24 5fvc:D 369 32 0.0339 0.0434 0.5000 7.6 5fvc:A, 5fvc:B, 5fvc:C, 5fvc:E, 5fvc:F, 5fvc:G, 5fvc:H, 5fvc:I, 5fvc:J, 5fvd:A, 5fvd:C, 8pdl:A, 8pdm:A, 8pdn:A, 8pdn:B, 8pdn:C, 8pdn:D, 8pdn:E, 8pdn:F, 8pdn:G, 8pdn:H, 8pdn:I, 8pdn:J, 8pdn:K, 8pdn:L, 8pdo:A, 8pdo:B, 8pdp:A, 8pdq:A, 8pdr:A, 8pdr:B, 8pdr:C, 8pdr:D, 8pdr:E, 8pdr:F, 8pdr:G, 8pdr:H, 8pdr:I, 8pdr:J, 8pdr:K, 8pds:A, 8pds:C
25 3b0g:A 538 63 0.0403 0.0353 0.3016 8.0 3b0j:A, 3b0l:A, 3b0m:A, 3b0n:A, 3vkp:A, 3vkq:A, 3vkr:A, 3vks:A, 3vkt:A, 3vlx:A, 3vly:A, 3vlz:A, 3vm0:A, 3vm1:A
26 3luf:B 246 37 0.0318 0.0610 0.4054 9.2 3luf:A, 3mf4:A, 3mf4:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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