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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ANVWGVRLADSLSSPTIETRTRHYTLHDFYSDLDASVGKEPWRPLRNQRTNEIVAVQLFRPLQGLVFDTQLYGFPGTFSQ
WEQFMKEKLRVLKYEVLRIYPISTYNHDRVNVFVANALVGAFLSNQAFYDLLPLLIVNDTMISDLLGTGAALSQFFQSHG
EVLEVAAGRKYLQMNNYSNDDDDPPLFAKDLSDYAKAFYSDTYEVLDRFFWTHDSSAGVLVHYDKPTNGNHYILGTLTQM
VSAPPHIINATDALLLESCLEQFAANVRARSAQPVTRLDQCYHLRWGAQYVGEDSLTYRLGVLSLLATNGYQLARPIPKQ
LTNRWLSSFVSQVVSDGINETPLWPQERYVQIAYDSPSVVDGATQYGYVRRNQLRLGMRISALQSLSDTPAPVQWLPQYT
IDQVAVDEGDAMVSQLTQLPLRPDYGSIWIGEALSYYVDYNRSHRVVLSSELPQLPDTYFDGDEQYGRSLFSLARKVGDR
SLVKDTAVLKHAYQAIDPNTGKEYLRAGQSVAYFGASAGHSGADQPLVIEPWMQGKISGVPPPSSVRQFGYDVAKGAIVD
LARPFPSGDYQFVYSDVDQVVDGHDDLSISSGLVESLLDSCVHATAPGGSFVMKINFPTRTVWHYIEQKILPNVTSYMLI
KPFVTNNVEVFFVAFGVHQQSALTWTSGVYFFLVDHFYRYETLSAISRQLPSFGYVDDGSSVTGIEIISIENPGFSNMTQ
AARVGISGLCANVGNARKSIAIYESHGARVLTITSRRSPASARRKARLRYLPLIDPRSLEVQARTILPSNPVLFDNINGA
SPHVCLTMMYNFEVSSAVYDGDVVLDLGTGPEAKILELIPSTSPVTCVDIRPTAQPNGCWNVRTTFLELDYLSDGWITGV
RGDIVTCMLSLGAAAAGKSMTFDAAFQQLVRVLTRSTANVLLIQVNCPTDVIRTIKGYLEIDQTNKRYKFPKFGRDEPYS
DMDSLERICRAAWPNCSITWVPLSYDLRWTKLALLESTTLSSASVRIAELMYKYMPIMRIDIHG

The query sequence (length=1024) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7yed:H 1288 1024 1.0000 0.7950 1.0000 0.0 7yed:I, 7yed:J, 7yed:K, 7yed:L, 7yev:H, 7yev:I, 7yev:J, 7yev:K, 7yev:L, 7yez:H, 7yez:I, 7yez:J, 7yez:K, 7yez:L
2 1eiz:A 180 119 0.0332 0.1889 0.2857 1.5 1ej0:A
3 6mni:A 258 79 0.0234 0.0930 0.3038 1.7 6mni:B
4 6ed2:A 591 170 0.0410 0.0711 0.2471 5.1
5 3rim:A 694 107 0.0254 0.0375 0.2430 6.2 3rim:C, 3rim:B, 3rim:D
6 2brr:Y 225 57 0.0166 0.0756 0.2982 6.3 2brr:H, 6f7t:H, 6f7t:B, 4hxb:H, 1uwx:H, 1uwx:M
7 6iig:A 495 54 0.0166 0.0343 0.3148 7.7 6cfg:B, 6ijt:A, 6in5:A, 6vmz:B, 6vmz:D, 6vmz:F, 5z88:A
8 6evj:B 752 51 0.0146 0.0199 0.2941 9.9 6evj:E, 6evk:B, 9f2r:B, 9f37:B, 6fhh:B, 6fhi:B, 5m3h:B, 6szu:B, 6szv:B, 6t0n:B, 6t0r:B, 6t0s:B, 6t0u:B, 6t0v:B, 6t2c:B, 6tw1:B, 4wsb:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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