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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ANRSIRDGDNPELLEERRMATFDTDKMAAVIYGSEEFARRRREITDAVSKIPELADIKPYPFLTREEKVTEGTRKISILT
KYLNQLIDRDNEEESLHLHREVIGYEGHPFALHDALFIPTLQSQASDEQQEKWLERARRREIIGCYAQTELGHGSNLRNL
ETTAVYDIASQEFVLHTPTTTALKWWPGALGKSCNYALVVAELNYGPHFFMVQLRDEKTHIPLKGVTVGDIGPKMNFNAA
DNGYLGLNNLRVPRTNLLMRHCKVEADGTYVKPPHAKIGYSGMVKIRSQMAMEQGLFLAHALTIAARYSAVRRQGHLDDK
QVEVKVLDYQTQQHRLFPSLARAYAFIFTGFETIHLYSQLLKDVDMGNTSGMADLHALTSGLKSVVAHETGEGIEQARMA
CGGHGYSMASYISVVYGIAIGGCTYAGENMVMLLQLARYLVKSVELIKAGKAKKLGPVASYLADKSDETDLTSLNGYVKM
FENMARRQAWKATEKFLKLMESGESREVAWNKSAVELTRASRLHTRLFIIEAFMRRVSRIEDIPVKEVLTDLLHLHVNYE
LLDVATYALEFMSFTQLDYVRDQLYLYLEKIRPNAVSLVDSFQISDMQLRSVLGRRDGHVYENLFKWAKSSPLNNADVLP
SVEKYLKPMMEKAKLAAAH

The query sequence (length=659) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5k3j:A 662 662 0.9970 0.9924 0.9924 0.0 5k3j:B
2 5k3i:A 661 665 0.6844 0.6823 0.6782 0.0 5k3i:B, 5k3i:C, 5k3i:D, 5k3i:E, 5k3i:F, 5k3i:G, 5k3i:H
3 1is2:A 637 647 0.4234 0.4380 0.4312 3.46e-172 2ddh:A, 1is2:B
4 7q86:A 612 642 0.4067 0.4379 0.4174 2.80e-156 7q86:B
5 2fon:B 656 668 0.3794 0.3811 0.3743 1.28e-135 2fon:A, 2fon:C
6 1w07:B 658 665 0.3809 0.3815 0.3774 2.08e-133 1w07:A
7 5ys9:A 692 667 0.3065 0.2919 0.3028 1.53e-93 5ys9:B
8 5y9d:A 687 678 0.3005 0.2882 0.2920 2.28e-83 5y9d:B
9 2pg0:A 380 341 0.1229 0.2132 0.2375 2.52e-07 2pg0:B
10 3sf6:A 387 143 0.0607 0.1034 0.2797 1.63e-05
11 2wbi:B 398 142 0.0592 0.0980 0.2746 2.84e-05 2wbi:A
12 3swo:A 388 129 0.0592 0.1005 0.3023 3.75e-05 3swo:D, 3swo:B, 3swo:C
13 2r0m:A 390 156 0.0546 0.0923 0.2308 3.97e-05 2r0n:A, 1siq:A, 1sir:A
14 8w0t:A 398 159 0.0592 0.0980 0.2453 1.68e-04 8w0t:B, 8w0t:C, 8w0t:D, 8w0u:A, 8w0u:B, 8w0u:C, 8w0u:D, 8w0z:A, 8w0z:B, 8w0z:C, 8w0z:D, 8w0z:E, 8w0z:F, 8w0z:G, 8w0z:H
15 7y0a:C 387 157 0.0546 0.0930 0.2293 2.00e-04 1jqi:A, 1jqi:B, 8sgs:A, 8sgs:B, 8sgs:C, 8sgs:D, 2vig:A, 2vig:B, 2vig:C, 2vig:D, 2vig:E, 2vig:F, 2vig:G, 2vig:H, 7y0a:A, 7y0a:B, 7y0a:D, 7y0b:A, 7y0b:B, 7y0b:C, 7y0b:D
16 4m9a:B 376 155 0.0592 0.1037 0.2516 0.005 4m9a:A
17 3oib:A 381 159 0.0637 0.1102 0.2642 0.005 3oib:B, 3p4t:A, 3p4t:B
18 4hr3:A 407 140 0.0546 0.0885 0.2571 0.007
19 5ol2:F 378 215 0.0713 0.1243 0.2186 0.017 5ol2:C
20 5lnx:D 374 244 0.0835 0.1471 0.2254 0.021 5lnx:A, 5lnx:B, 5lnx:C, 5lnx:E, 5lnx:F, 5lnx:G, 5lnx:H
21 2z1q:B 549 151 0.0592 0.0710 0.2583 0.021 2z1q:A
22 3r7k:A 378 166 0.0653 0.1138 0.2590 0.047 3r7k:B, 3r7k:C, 3r7k:D
23 4n5f:A 378 154 0.0561 0.0979 0.2403 0.049 4n5f:B
24 3gqt:C 385 144 0.0577 0.0987 0.2639 0.057 3d6b:C, 3eon:C, 3gnc:A, 3gnc:B, 3gnc:C, 3gnc:D, 3gqt:A, 3gqt:B
25 6wy8:B 384 70 0.0364 0.0625 0.3429 0.067 6wy8:D, 6wy9:A
26 6t3e:B 325 66 0.0349 0.0708 0.3485 0.069 6t3e:A
27 3owa:C 587 136 0.0577 0.0647 0.2794 0.084 3owa:A, 3owa:B, 3owa:D
28 2ix6:A 416 54 0.0273 0.0433 0.3333 0.087 2ix5:A, 2ix5:B, 2ix5:C, 2ix5:D, 2ix6:C, 2ix6:F, 2ix6:B, 2ix6:E, 2ix6:D
29 4iv6:B 383 135 0.0546 0.0940 0.2667 0.097 4iv6:A
30 6fah:D 379 145 0.0592 0.1029 0.2690 0.14 6fah:C
31 2dvl:A 370 134 0.0577 0.1027 0.2836 0.15 2dvl:B
32 1nee:A 135 99 0.0470 0.2296 0.3131 0.16
33 7szv:A 372 140 0.0501 0.0887 0.2357 0.29 7szv:B
34 2a1t:C 388 142 0.0501 0.0851 0.2324 0.31 2a1t:A, 2a1t:B, 2a1t:D, 1egc:A, 1egc:B, 1egc:C, 1egc:D, 1egd:A, 1egd:B, 1egd:C, 1egd:D, 1ege:A, 1ege:B, 1ege:C, 1ege:D, 4p13:A, 4p13:B, 4p13:C, 4p13:D, 8sgp:A, 8sgp:B, 8sgp:C, 8sgp:D, 1t9g:A, 1t9g:B, 1t9g:C, 1t9g:D
35 3mdd:A 385 139 0.0486 0.0831 0.2302 0.35 3mdd:B, 3mde:A, 3mde:B, 1udy:A, 1udy:B, 1udy:C, 1udy:D
36 4x28:A 386 49 0.0273 0.0466 0.3673 0.39 4x28:B
37 3pfd:C 369 139 0.0546 0.0976 0.2590 0.46 3pfd:A, 3pfd:B, 3pfd:D
38 1ukw:A 379 376 0.1305 0.2269 0.2287 0.82 1ukw:B
39 2eba:A 380 58 0.0258 0.0447 0.2931 1.0 2eba:D, 2eba:C, 2eba:E, 2eba:F, 2eba:G, 2eba:H, 2eba:I
40 7w0j:E 382 139 0.0501 0.0864 0.2374 1.1 8i4p:A, 8i4r:A, 7w0j:B, 7w0j:C, 7w0j:H
41 2d29:A 386 168 0.0592 0.1010 0.2321 1.2 2d29:B
42 7rgn:A 340 108 0.0440 0.0853 0.2685 1.8
43 7s7g:A 571 136 0.0440 0.0508 0.2132 1.9 3b96:A, 2uxw:A
44 5w21:A 922 76 0.0303 0.0217 0.2632 2.3 7ysh:A, 7ysu:A, 7ysw:A
45 6cu5:A 314 51 0.0258 0.0541 0.3333 3.0 6cu5:B, 8ft7:A, 8ft7:B
46 8sgr:A 393 61 0.0273 0.0458 0.2951 3.3 1ivh:A, 1ivh:B, 1ivh:C, 1ivh:D, 8sgr:B, 8sgr:C, 8sgr:D
47 4s1k:A 236 54 0.0258 0.0720 0.3148 6.2 4s1l:A, 4zqx:A
48 3nf4:A 369 148 0.0531 0.0949 0.2365 6.3 3nf4:B
49 4irn:A 378 43 0.0258 0.0450 0.3953 8.8 4irn:B, 4irn:C, 4irn:D, 4irn:E, 4irn:F, 4irn:G, 4irn:H
50 4fgm:A 587 57 0.0258 0.0290 0.2982 9.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218