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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ANRAYPYTRLRRNRRDDFSRRLVRENVLTVDDLILPVFVLDGVNQRESIPSMPGVERLSIDQLLIEAEEWVALGIPALAL
FPVTPVEKKSLDAAEAYNPEGIAQRATRALRERFPELGIITDVCLCEFTTHGQCGILDDDGYVLNDVSIDVLVRQALSHA
EAGAQVVAPSDMMDGRIGAIREALESAGHTNVRVMAYSAKYASAYYGPFRDANRATYQMDPANSDEALHEVAADLAEGAD
MVMVKPGMPYLDIVRRVKDEFRAPTFVYQVSGEYAMHMGAIQNGWLAESVILESLTAFKRAGADGILTYFAKQAAEQLRR

The query sequence (length=320) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2c18:A 333 330 0.9844 0.9459 0.9545 0.0 1b4k:A, 1b4k:B, 2c14:B, 2c15:B, 2c16:B, 2c18:B, 2c19:B, 1gzg:A, 1gzg:B, 1w54:A, 1w56:A, 1w56:B, 1w5m:A, 1w5m:B, 1w5n:A, 1w5n:B, 1w5o:A, 1w5o:B, 1w5p:A, 1w5p:B, 1w5q:A, 1w5q:B, 2woq:A
2 2c1h:A 319 308 0.5094 0.5110 0.5292 2.90e-109 2c1h:B, 1w1z:A, 1w1z:B
3 3obk:A 352 321 0.4719 0.4290 0.4704 3.69e-93 3obk:B, 3obk:C, 3obk:D, 3obk:E, 3obk:F, 3obk:G, 3obk:H
4 5lzl:A 336 330 0.4906 0.4673 0.4758 3.44e-89 5lzl:B, 5lzl:D, 5lzl:E, 5lzl:F, 5lzl:G, 5lzl:I, 5lzl:J, 5lzl:K, 5lzl:L
5 1b4e:A 323 317 0.4031 0.3994 0.4069 5.67e-76 1i8j:A, 1i8j:B, 1l6s:A, 1l6s:B, 1l6y:A, 1l6y:B, 5mhb:A
6 5hms:A 330 305 0.4281 0.4152 0.4492 1.44e-75 1e51:A, 5hms:B, 5hnr:A
7 1h7r:A 342 312 0.3812 0.3567 0.3910 1.61e-62 1aw5:A, 1eb3:A, 1gjp:A, 1h7n:A, 1h7o:A, 1h7p:A, 1ohl:A, 1qml:A, 1qnv:A, 1w31:A, 1ylv:A
8 1pv8:A 276 297 0.3875 0.4493 0.4175 3.98e-57
9 6hwh:V 550 94 0.0750 0.0436 0.2553 1.3 6hwh:Q
10 2r6f:A 899 177 0.1437 0.0512 0.2599 5.8
11 8cp2:A 600 51 0.0531 0.0283 0.3333 5.9 8cp2:B, 8cp5:A, 8cp5:B
12 8ro0:C 898 56 0.0563 0.0200 0.3214 9.1 8ro1:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218