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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKR
KGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKAL

The query sequence (length=154) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4v6i:BT 189 154 1.0000 0.8148 1.0000 4.84e-109 8aaf:E, 8agt:E, 8agu:E, 8agv:E, 8agw:E, 8agx:E, 8agz:E, 5apn:R, 5apo:R, 7azy:H, 7b7d:Ln, 8bip:LR, 8bjq:LR, 8bn3:M9, 8bqd:BF, 8bqx:BF, 7bt6:R, 7btb:R, 8ccs:D, 8cdl:D, 8cdr:D, 8ceh:D, 8cf5:D, 8cg8:D, 8cgn:D, 8civ:D, 8cku:D, 8cmj:D, 5dat:M9, 5dat:m9, 5dc3:M9, 5dc3:m9, 5dge:M9, 5dge:m9, 5dgf:M9, 5dgf:m9, 5dgv:M9, 5dgv:m9, 8eub:AR, 8evp:AR, 8evq:AR, 8evr:AR, 8evs:AR, 8evt:AR, 8ewb:AR, 8ewc:AR, 5fci:M9, 5fci:m9, 5fcj:M9, 5fcj:m9, 6ft6:R, 5gak:T, 6gq1:R, 6gqb:R, 6gqv:R, 5h4p:R, 6hd7:T, 8hfr:RP, 6hhq:z, 6hhq:CT, 5i4l:M9, 5i4l:m9, 6i7o:BF, 6i7o:YF, 3j6x:59, 3j6y:59, 3j77:69, 3j78:69, 3jct:R, 5jcs:R, 5juo:W, 5jup:W, 5jus:W, 5jut:W, 5juu:W, 8k2d:LR, 8k82:LR, 5lyb:M9, 5lyb:m9, 5m1j:R5, 6m62:R, 5mc6:BF, 5mei:z, 5mei:CT, 7mpi:AR, 7mpj:AR, 6n8j:R, 6n8k:R, 6n8l:R, 6n8m:e, 6n8n:e, 6n8o:e, 7n8b:AR, 5ndg:M9, 5ndg:m9, 5ndv:M9, 5ndv:m9, 5ndw:M9, 5ndw:m9, 7nrc:LT, 7nrd:LT, 5obm:M9, 5obm:m9, 7of1:R, 7oh3:R, 7ohq:R, 6oig:R, 5on6:z, 5on6:CT, 7osa:eL19, 7osm:eL19, 8p8m:QQ, 8p8n:QQ, 8p8u:QQ, 8pfr:QQ, 6q8y:BF, 6qik:R, 6qt0:R, 6qtz:R, 6r84:T, 6r86:T, 6r87:T, 6ri5:R, 7rr5:LR, 6rzz:R, 6s05:R, 6s47:AT, 6snt:x, 6sv4:BF, 6sv4:YF, 6sv4:ZF, 6t4q:LR, 5t62:e, 5t6r:e, 6t7i:LR, 6t7t:LR, 6t83:Ry, 6t83:C, 5tbw:z, 5tbw:CT, 6tb3:BF, 5tga:M9, 5tga:m9, 5tgm:M9, 5tgm:m9, 6tnu:BF, 7too:AL19, 7top:AL19, 7u0h:R, 4u3m:M9, 4u3m:m9, 4u3n:M9, 4u3n:m9, 4u3u:M9, 4u3u:m9, 4u4n:M9, 4u4n:m9, 4u4o:M9, 4u4o:m9, 4u4q:M9, 4u4q:m9, 4u4r:M9, 4u4r:m9, 4u4u:M9, 4u4u:m9, 4u4y:M9, 4u4y:m9, 4u4z:M9, 4u4z:m9, 4u50:M9, 4u50:m9, 4u51:M9, 4u51:m9, 4u52:M9, 4u52:m9, 4u53:M9, 4u53:m9, 4u55:M9, 4u55:m9, 4u56:M9, 4u56:m9, 4u6f:M9, 4u6f:m9, 7ug6:R, 7uoo:R, 7uqb:R, 7uqz:R, 7v08:R, 4v4b:BP, 4v7f:R, 4v7r:BS, 4v7r:DS, 4v88:BR, 4v88:DR, 4v8t:R, 4v8y:BR, 4v8z:BR, 4v91:R, 6woo:R, 2ww9:J, 2wwa:J, 2wwb:J, 6xiq:R, 6xir:R, 8y0u:LR, 6ylg:R, 6ylh:R, 6ylx:R, 6yly:R, 7z34:R, 6z6j:LR, 6z6k:LR, 7zpq:BQ, 7zrs:BQ, 7zs5:BS, 7zuw:BQ, 7zux:EQ, 7zw0:LU
2 4v7h:BP 176 141 0.9156 0.8011 1.0000 3.41e-90
3 5it7:RR 188 154 0.8701 0.7128 0.8701 8.00e-88 6uz7:AR
4 7nac:R 134 154 0.8247 0.9478 0.8247 2.25e-82 6elz:R, 6em5:R, 7nad:R, 7naf:R, 7ohr:R, 7r72:R, 7r7a:R, 8v87:R
5 8c3a:z 179 154 0.8182 0.7039 0.8182 2.18e-80 8c3a:BM, 8cq7:z, 8cq7:BM, 8cqw:z, 8cqw:BM, 8cre:z, 8cre:BM, 8oeq:z, 8oeq:BM, 7pzy:z, 7q08:z, 7q0f:z, 7q0p:z, 7q0r:z, 8q5i:z
6 7r81:T1 191 153 0.6883 0.5550 0.6928 1.76e-65 7olc:LR, 7old:LR, 8onz:LR, 8oo0:LR, 8pv1:LR, 8pv2:LR, 8pv3:LR, 8pv4:LR, 8pv5:LR, 8pv6:LR, 8pv7:LR, 8pv8:LR, 8pvk:LR, 8pvl:LR, 7z3n:LR, 7z3o:LR
7 4v6w:CR 203 154 0.5974 0.4532 0.5974 7.79e-65 6xu6:CR, 6xu7:CR, 6xu8:CR
8 8eui:R 149 149 0.6623 0.6846 0.6846 2.29e-61 8etg:R, 8etj:R, 8eug:R
9 8azw:H 182 153 0.6169 0.5220 0.6209 1.10e-57 8b2l:H3, 7qiw:T, 7qix:X, 7qiz:T
10 9bh5:CR 194 154 0.5779 0.4588 0.5779 1.90e-57 9cai:CR
11 4v3p:LT 189 153 0.6104 0.4974 0.6144 1.80e-56 8ip8:LA, 8ipa:LA, 8ipb:LA, 8jiv:CR, 4v7e:CR
12 6zj3:Lf 170 166 0.5649 0.5118 0.5241 1.83e-56
13 5xxb:Q 176 153 0.6039 0.5284 0.6078 7.42e-56
14 4v6x:CR 189 152 0.6039 0.4921 0.6118 8.20e-55 7a01:32, 8a3d:L, 5aj0:AR, 8b5l:R, 8b6c:R, 9bdl:AL19, 9bdn:AL19, 9bdp:AL19, 8bf9:R, 7bhp:LR, 8bhf:E1, 8bpo:Q2, 8btk:BR, 7cpu:LR, 7cpv:LR, 4d5y:R, 4d67:R, 6d90:R, 6d9j:R, 9f1b:BR, 9f1c:BR, 9f1d:BR, 7f5s:LR, 8fl2:LD, 8fl3:LD, 8fl4:LD, 8fl6:LD, 8fl7:LD, 8fl9:LD, 8fla:LD, 8flb:LD, 8flc:LD, 8fld:LD, 8fle:LD, 8flf:LD, 9fpz:LR, 9fq0:LR, 6frk:R, 6ftg:R, 6fti:R, 6ftj:R, 8g5y:LR, 8g5z:LR, 8g60:LR, 8g61:LR, 8g6j:LR, 8glp:LR, 6gz3:AR, 6gz4:AR, 6gz5:AR, 6hcf:R3, 6hcj:R3, 6hcm:R3, 6hcq:R3, 8idt:a, 8idy:a, 8ie3:a, 8ifd:2L, 8ife:2L, 8ine:a, 8inf:a, 8ink:a, 6ip5:2L, 6ip6:2L, 6ip8:2L, 8ipd:a, 8ipx:a, 8ipy:a, 8ir1:a, 8ir3:a, 3j7o:R, 3j7p:R, 3j7q:R, 3j7r:R, 3j92:R, 3jag:R, 3jah:R, 3jai:R, 3jaj:R, 3jan:R, 8jdj:W, 8jdk:W, 8jdl:W, 8jdm:W, 8k2c:LR, 5lks:LR, 6lqm:a, 6lsr:a, 6lss:a, 7ls1:L2, 7ls2:L2, 6lu8:a, 5lzs:R, 5lzt:R, 5lzu:R, 5lzv:R, 5lzw:R, 5lzx:R, 5lzy:R, 5lzz:R, 7mdz:R, 6mtb:R, 6mtc:R, 6mtd:R, 6mte:R, 7nfx:R, 7nwg:R3, 7nwh:R, 7nwi:R, 7o7y:BR, 7o7z:BR, 7o80:BR, 7o81:BR, 7obr:R, 8ohd:LR, 8oj0:LR, 8oj5:LR, 8oj8:LR, 6ole:S, 6olf:S, 6olg:AR, 6oli:S, 6olz:AR, 6om0:S, 6om7:S, 8ony:LR, 7oya:R1, 7oyb:R1, 7oyc:R1, 7oyd:R, 8p2k:BR, 6p5i:AR, 6p5j:AR, 6p5k:AR, 6p5n:AR, 8q7z:BR, 8q87:BR, 8qfd:R, 7qgg:S, 8qoi:LR, 7qvp:LR, 7qvp:MR, 7qwq:R, 7qwr:R, 7qws:R, 6qzp:LR, 6r5q:R, 6r6g:R, 6r6p:R, 6r7q:R, 8rjb:R, 8rjc:R, 8rjd:R, 8scb:R, 6sgc:R2, 6swa:o, 6sxo:LR, 5t2c:L, 6t59:R3, 7tm3:R, 7toq:AL19, 7tor:AL19, 7tut:R, 7ucj:R, 7uck:R, 4ug0:LR, 4ujc:BR, 4ujd:AR, 4uje:CR, 6xa1:LR, 7xnx:LR, 7xny:LR, 8xsx:LR, 8xsy:LR, 8xsz:LR, 6y0g:LR, 8y0w:LR, 8y0x:LR, 6y2l:LR, 6y57:LR, 6y6x:LR, 8yoo:LR, 8yop:LR, 6z6l:LR, 6z6m:LR, 6z6n:LR, 7zjw:LU, 7zjx:LU, 6zm7:LR, 6zme:LR, 6zmi:LR, 6zmo:LR, 6zvk:32
15 5xy3:R 162 154 0.5455 0.5185 0.5455 1.96e-52
16 8br8:LS 192 142 0.5260 0.4219 0.5704 1.64e-51 8brm:LS, 8bsi:LS, 8bsj:LS, 8btd:LS, 8btr:LS, 8fru:R, 7pwg:R, 7pwo:R2
17 7ohv:R 89 127 0.5779 1.0000 0.7008 2.27e-51
18 4v8p:BO 184 146 0.5714 0.4783 0.6027 1.63e-50 4v8p:EO, 4v8p:GO
19 4v8p:CO 175 145 0.5649 0.4971 0.6000 2.74e-49
20 8i9z:LR 148 153 0.5779 0.6014 0.5817 7.19e-48 8i9x:LR, 8i9y:LR, 8ia0:LR
21 8rxh:LQ 201 153 0.5325 0.4080 0.5359 8.55e-48 8a3w:Q, 8a98:Q, 6az3:Q, 3jcs:Q, 8ovj:Q, 8rxx:LQ, 5t2a:R
22 3j79:T 181 153 0.5455 0.4641 0.5490 9.14e-47 3jbn:AT, 3jbo:AT, 3jbp:AT, 8tpu:AT, 5umd:T
23 4v8m:BT 199 153 0.5195 0.4020 0.5229 7.96e-46 8ova:BT, 8ove:BT, 5t5h:T
24 6w6l:S 156 152 0.5455 0.5385 0.5526 2.62e-43 8fky:LD, 8fkz:LD, 7ow7:L
25 8etc:R 124 145 0.5519 0.6855 0.5862 3.02e-43 8esq:R, 8esr:R
26 6zu5:LR0 161 152 0.3896 0.3727 0.3947 2.25e-37
27 7qep:M9 170 148 0.3831 0.3471 0.3986 9.84e-37
28 4v5z:Bp 159 146 0.4870 0.4717 0.5137 1.94e-34
29 8p5d:LR0 164 148 0.3961 0.3720 0.4122 4.62e-34 8p60:LR0, 8p60:KR0, 7qca:LR0
30 6rm3:LR0 165 146 0.3766 0.3515 0.3973 1.95e-33
31 6skf:BS 146 135 0.3442 0.3630 0.3926 2.31e-32 6skg:BS, 6th6:BS
32 4v4n:AQ 150 136 0.3312 0.3400 0.3750 1.27e-29 4v6u:BQ
33 4v9f:P 144 140 0.3312 0.3542 0.3643 9.45e-22 3cc2:P, 3cc4:P, 3cc7:P, 3cce:P, 3ccj:P, 3ccl:P, 3ccm:P, 3ccq:P, 3ccr:P, 3ccs:P, 3ccu:P, 3ccv:P, 3cd6:P, 3cma:P, 3cme:P, 3cpw:O, 3cxc:O, 1ffk:M, 3g4s:P, 3g6e:P, 3g71:P, 3i55:P, 3i56:P, 1jj2:O, 1k73:Q, 1k8a:Q, 1k9m:Q, 1kc8:Q, 1kd1:Q, 1kqs:O, 1m1k:Q, 1m90:Q, 1n8r:Q, 1nji:Q, 2otj:P, 2otl:P, 3ow2:O, 1q7y:Q, 1q81:Q, 1q82:Q, 1q86:Q, 2qa4:P, 2qex:P, 1qvf:O, 1qvg:O, 1s72:P, 1vq4:P, 1vq5:P, 1vq6:P, 1vq7:P, 1vq8:P, 1vq9:P, 1vqk:P, 1vql:P, 1vqm:P, 1vqn:P, 1vqo:P, 1vqp:P, 1w2b:O, 1yhq:P, 1yi2:P, 1yij:P, 1yit:P, 1yj9:P, 1yjn:P, 1yjw:P
34 8hku:L19E 144 134 0.3117 0.3333 0.3582 2.14e-20 8hkv:L19E, 8hky:L19E, 8hkz:L19E, 8hl1:L19E, 8hl2:L19E, 8hl3:L19E, 8hl4:L19E, 8hl5:L19E
35 7f0d:T 98 37 0.1039 0.1633 0.4324 1.1 7kgb:T, 7msc:T, 7msh:T, 7msm:T, 7msz:T, 7mt2:T, 7mt3:T, 7mt7:T, 7sfr:T, 5v7q:T, 5v93:T
36 8rsl:A 271 67 0.1688 0.0959 0.3881 1.4 5kiv:A, 8rsl:B
37 4ej0:A 330 33 0.0779 0.0364 0.3636 2.2 4ej0:B, 4ej0:C, 4ej0:D, 4ej0:E, 4ej0:F, 4ej0:G, 4ej0:H, 4ej0:I, 4ej0:J
38 6gej:Y 447 45 0.1234 0.0425 0.4222 3.1 8ets:W, 8ets:U, 8ets:Y, 8etu:W, 8etu:U, 8etu:Y, 8etw:W, 8etw:U, 8etw:Y, 8eu9:W, 8eu9:U, 8eu9:Y, 8euf:W, 8euf:U, 8euf:Y, 6gej:U, 6gej:W, 6gen:U, 6gen:W, 6gen:Y
39 6dzi:U 97 37 0.0909 0.1443 0.3784 4.4 6dzp:U, 8fr8:Z, 8kab:U, 5o60:U, 5o61:U, 7s0s:V, 8v9j:V, 8v9k:V, 8v9l:V, 8whx:W, 8why:W, 8wi7:W, 8wi8:W, 8wib:W, 8wic:W, 7xam:U, 5xym:T, 8xz3:U, 7y41:U, 5zeb:U, 5zep:U, 5zet:U
40 1ddz:A 481 42 0.0909 0.0291 0.3333 9.0 1ddz:B
41 4xyj:A 768 43 0.0909 0.0182 0.3256 9.4 4rh3:A, 4rh3:B, 4rh3:C, 4rh3:D, 4u1r:A, 4u1r:B, 4u1r:C, 4u1r:D, 4wl0:A, 4wl0:B, 4wl0:C, 4wl0:D, 4xyj:B, 4xyj:C, 4xyj:D, 4xyj:E, 4xyj:F, 4xyj:G, 4xyj:H, 4xyk:A, 4xyk:B, 4xyk:C, 4xyk:D, 4xz2:A, 4xz2:B, 4xz2:C, 4xz2:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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