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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AMSICPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTMKCGTCHEINSGATFMCLQCGFCGCWNHSHFLSHSK
QIGHIFGINSNNGLLFCFKCEDYIGNIDLINDAILAKYWDDVCTKTMVPSMERRDGLSGLINMGNTCFMSSILQCLIHNP
YFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGALNTNRQTGFIYLLTCAWKINQNQDAHEFWQFIINQIHQSYVL
DLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYH
CGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTSENGKVPDIIYELIGIVSHKG
TVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIRQVN

The query sequence (length=450) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3mhs:A 455 462 0.9800 0.9692 0.9545 0.0 6aqr:A, 4fip:A, 4fip:E, 4fjc:A, 4fk5:A, 6t9l:K, 4w4u:A, 4wa6:A, 4zux:U, 4zux:Z, 4zux:e, 4zux:j
2 4fjc:E 434 456 0.9489 0.9839 0.9364 0.0 3m99:A, 3mhh:A
3 4wa6:D 415 449 0.9200 0.9976 0.9220 0.0 4w4u:D
4 8bs3:A 324 313 0.2267 0.3148 0.3259 3.16e-45 8bs9:A, 8bs9:C
5 7r2g:B 351 343 0.2356 0.3020 0.3090 1.84e-38 6cpm:C, 6cpm:D, 6crn:A, 6crn:B, 6crn:C, 6crn:D, 6gh9:A, 6gha:A, 6ml1:A, 6ml1:B, 7r2g:A
6 5k16:B 328 330 0.2378 0.3262 0.3242 9.22e-38 5cvm:A, 5k16:A, 5k1c:A, 5l8h:A, 5l8w:A
7 2hd5:A 315 347 0.2467 0.3524 0.3199 1.48e-36
8 2y6e:B 339 340 0.2244 0.2979 0.2971 3.85e-36 2y6e:A, 2y6e:C, 2y6e:E, 2y6e:F
9 3nhe:A 338 359 0.2467 0.3284 0.3092 2.17e-34 6dgf:A, 2ibi:A, 3v6c:A, 3v6e:A, 5xu8:A, 5xve:A
10 3n3k:A 355 344 0.2333 0.2958 0.3052 2.46e-34 2gfo:A, 8xpn:A, 8xpn:B
11 5cvn:B 321 335 0.2267 0.3178 0.3045 4.57e-34 5cvo:B, 5cvo:E, 6jlq:A
12 2y5b:E 325 334 0.2244 0.3108 0.3024 4.30e-33 3i3t:A, 3i3t:C, 3i3t:E, 3i3t:G, 3mtn:A, 3mtn:C, 2y5b:A
13 5k1b:A 264 320 0.2267 0.3864 0.3187 6.36e-30
14 5wch:A 350 324 0.1978 0.2543 0.2747 1.33e-29 5wch:B, 5wch:C, 5wch:D
15 8xpn:C 327 338 0.2289 0.3150 0.3047 1.83e-27
16 5ohk:A 304 317 0.1978 0.2928 0.2808 2.29e-27 5ohn:A, 5ohn:C
17 8itn:A 350 331 0.2044 0.2629 0.2779 1.66e-25 8itn:C, 8itp:D, 8itp:B
18 5gvi:A 326 342 0.1933 0.2669 0.2544 3.96e-24
19 5k1a:A 239 314 0.2022 0.3808 0.2898 1.91e-23 5k1a:C, 5k1a:E, 5k1a:G
20 8d1t:A 330 340 0.2000 0.2727 0.2647 1.31e-22 8d0a:A, 5ohp:A
21 5n9t:A 357 305 0.1822 0.2297 0.2689 9.29e-20 8d4z:A, 8d4z:B, 6f5h:A, 6f5h:B, 6m1k:A, 6m1k:B, 5n9r:A, 5n9r:B, 5n9t:B, 5nge:A, 5ngf:A, 5ngf:B, 5uqv:A, 5uqv:B, 5uqx:A, 5uqx:B, 6vn2:A, 6vn2:B, 6vn3:A, 6vn3:B, 6vn4:A, 6vn4:B, 6vn5:A, 6vn5:B, 6vn6:A, 6vn6:B, 5vs6:A, 5vs6:B, 5vsb:A, 5vsb:B, 5vsk:A, 5whc:A, 5whc:B, 7xhh:A, 7xhh:B, 7xhk:B
22 7w3u:A 343 330 0.1733 0.2274 0.2364 1.33e-17 7w3r:A, 7w3u:B, 7w3u:C
23 8p14:A 331 313 0.1778 0.2417 0.2556 1.48e-15 8hje:A, 7tuo:A
24 5cht:A 308 333 0.1911 0.2792 0.2583 3.03e-15 5cht:B, 5chv:A, 5chv:B
25 5txk:A 317 340 0.2022 0.2871 0.2676 4.43e-15
26 8a9k:D 285 323 0.1844 0.2912 0.2570 1.65e-13 7ay0:D, 7zh4:D
27 9fcj:D 312 336 0.1956 0.2821 0.2619 1.97e-13 7ay0:B, 9fci:D
28 3ihp:B 681 369 0.1711 0.1131 0.2087 3.00e-12 6dxh:A, 6dxt:A, 6dxt:B, 2g43:A, 2g43:B, 2g45:A, 2g45:D, 3ihp:A, 7ms5:A, 7ms5:B, 7ms6:A, 7ms7:A, 7ms7:B, 6nft:A, 6nft:B, 6p9g:A
29 7ay1:D 341 347 0.1911 0.2522 0.2478 3.80e-12 8a9j:D, 7ay2:B, 7zh3:D
30 5nge:B 313 330 0.1667 0.2396 0.2273 1.04e-11 5vsk:B
31 6iil:A 341 363 0.1800 0.2375 0.2231 5.28e-09 6iik:A, 6iik:B, 6iil:B, 6iim:A, 6iim:B, 6iin:A, 6iin:B
32 8y6o:U 458 447 0.2000 0.1965 0.2013 4.25e-08 8h6e:4T, 8h6j:4T, 6qw6:U, 6qx9:U
33 6h4h:A 458 262 0.1422 0.1397 0.2443 5.34e-08 6h4h:B, 8p1p:A
34 6h4h:A 458 51 0.0422 0.0415 0.3725 0.009 6h4h:B, 8p1p:A
35 8p1q:A 439 261 0.1356 0.1390 0.2337 7.49e-05 8p1p:B, 8p1q:B
36 8p1q:A 439 51 0.0422 0.0433 0.3725 0.005 8p1p:B, 8p1q:B
37 3c5k:A 108 93 0.0533 0.2222 0.2581 0.054 5b8d:A, 6ce6:A, 6ce8:A, 6cea:A, 6cec:A, 6ced:A, 6cee:A, 6cef:A, 8g43:A, 8g44:A, 8g45:A, 3gv4:A, 5kh3:A, 5kh7:A, 5kh9:A, 3phd:A, 3phd:B, 3phd:C, 3phd:D, 5wbn:A, 5wpb:A, 7zyu:A
38 5g0f:A 110 60 0.0378 0.1545 0.2833 0.067
39 7ay2:E 203 164 0.0822 0.1823 0.2256 2.9
40 5v8f:D 456 68 0.0378 0.0373 0.2500 4.1 7mca:D, 6rqc:D, 5zr1:D
41 6wgc:D 436 68 0.0378 0.0390 0.2500 4.9 7tjf:D, 7tjh:D, 7tji:D, 7tjj:D, 7tjk:D, 6wgg:D, 6wgi:D
42 6l7c:A 253 92 0.0444 0.0791 0.2174 6.3 6l7c:B, 6l7c:C, 6l7c:D, 6l7c:E, 6l7c:F, 6l7c:G, 6l7c:H, 6l7c:I
43 7mqa:SP 2485 69 0.0356 0.0064 0.2319 6.8
44 4q8g:B 353 53 0.0400 0.0510 0.3396 7.1 4q8g:A
45 7suk:LP 359 95 0.0467 0.0585 0.2211 7.8 5wlc:LP
46 2i50:A 122 54 0.0311 0.1148 0.2593 9.0
47 6r9j:A 595 53 0.0400 0.0303 0.3396 9.0 6r9o:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218