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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AMPGPPLGPVLGQRGVSINQFCKEFNERTKDIKEGIPLPTKILVKPDRTFEIKIGQPTVSYFLKAAAGIEKGARQTGKEV
AGLVTLKHVYEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGIRVVKDLSSEELAAFQKERAIFLAAQKEADLAAQEE
AA

The query sequence (length=162) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6gaw:BK 176 152 0.8827 0.8125 0.9408 3.00e-103 7a5f:J3, 7a5g:J3, 7a5h:J, 7a5i:J3, 7a5j:J, 7a5k:J3, 5aj4:BK, 8any:J, 6gb2:BK, 6i9r:J, 3j7y:J, 3j9m:J, 8k2a:LK, 8k2b:LK, 7l08:J, 7l20:J, 7nqh:BK, 7nql:BK, 7nsh:BK, 7nsi:BK, 7nsj:BK, 6nu2:J, 6nu3:J, 7o9k:J, 7o9m:J, 7odr:J, 7ods:J, 7odt:J, 7of0:J, 7of2:J, 7of3:J, 7of4:J, 7of5:J, 7of6:J, 7of7:J, 7og4:XJ, 7oi6:J, 7oi7:J, 7oi8:J, 7oi9:J, 7oia:J, 7oib:J, 7oic:J, 7oid:J, 7oie:J, 8oin:BQ, 8oiq:BQ, 8oir:BQ, 8oit:BQ, 5ool:J, 5oom:J, 7pd3:J, 8pk0:J, 7po4:J, 7qi4:J, 7qi5:J, 7qi6:J, 8qsj:J, 8qu1:J, 8qu5:J, 4v19:K, 6vlz:J, 6vmi:J, 8xt0:LK, 8xt1:LK, 8xt2:LK, 8xt3:LK, 6ydp:BK, 6ydw:BK, 6zm5:J, 6zm6:J, 6zs9:XJ, 6zsa:XJ, 6zsb:XJ, 6zsc:XJ, 6zsd:XJ, 6zse:XJ, 6zsg:XJ
2 6ywe:g 147 135 0.3827 0.4218 0.4593 6.36e-37 6yws:g, 6ywv:g, 6ywx:g, 6ywy:g
3 6xyw:Ai 138 129 0.3395 0.3986 0.4264 8.68e-35
4 2jq7:A 134 128 0.3580 0.4328 0.4531 2.64e-29 1mms:A, 1mms:B, 1oln:A, 4v4p:AL, 4v4r:BK, 4v4s:BK, 4v4t:BK
5 5ady:I 141 130 0.3333 0.3830 0.4154 1.67e-28 7abz:I, 5afi:I, 5aka:I, 7bl2:I, 7bl3:I, 7bl5:I, 6bu8:11, 7bv8:J, 6by1:CI, 6by1:DI, 6c4i:J, 7cpj:I, 4csu:I, 7d6z:I, 7d80:h, 3deg:H, 6dnc:M, 8fiz:BL, 8fzd:J, 8fze:J, 8fzf:J, 8fzg:J, 8fzh:J, 8fzi:J, 8fzj:J, 8g7p:J, 8g7q:J, 5gad:J, 5gae:J, 5gaf:J, 5gag:J, 5gah:J, 6gwt:I, 6gxm:I, 6gxn:I, 6gxo:I, 6gxp:I, 5h5u:J, 6hrm:I, 6i0y:I, 6i7v:DJ, 6i7v:CJ, 5iqr:I, 5it8:CJ, 5it8:DJ, 3j0d:G, 2j28:I, 3j5l:I, 5j5b:CJ, 5j5b:DJ, 3j7z:I, 5j7l:CJ, 5j7l:DJ, 3j8g:I, 5j88:CJ, 5j88:DJ, 5j8a:CJ, 5j8a:DJ, 3j9y:I, 3j9z:LE, 5j91:CJ, 5j91:DJ, 3ja1:LK, 3jbv:i, 3jcd:I, 3jce:I, 3jcj:H, 3jcn:I, 5jc9:CJ, 5jc9:DJ, 7jsz:i, 5jte:BI, 7jt3:i, 5ju8:BI, 7k50:i, 7k51:i, 7k52:i, 7k53:i, 7k54:i, 7k55:i, 5kcr:1K, 5kcs:1K, 5kps:I, 5kpv:H, 5kpw:H, 5kpx:H, 5l3p:K, 6lkq:Z, 7lv0:i, 5lza:I, 5lzb:I, 5lzc:I, 5lzd:I, 5lze:I, 5lzf:I, 7m5d:I, 5mdv:I, 5mdw:I, 5mdy:I, 5mdz:I, 7n1p:LK, 7n2c:LK, 7n2v:LK, 5nco:J, 5np6:g, 5nwy:V, 7nwt:I, 5o2r:I, 6o9j:6, 6o9k:I, 7oj0:9, 8p16:I, 8p17:I, 8p18:I, 8peg:k, 8phj:6, 6pj6:Q, 7pjs:I, 7pjt:I, 7pju:I, 7pjv:I, 7pjw:I, 7pjx:I, 7pjy:I, 7pjz:I, 8pkl:k, 6q97:I, 6q98:I, 6q9a:I, 7qg8:V, 7qgh:V, 7qgn:V, 7qgr:V, 8qk7:I, 6s0k:J, 7sa4:I, 7ss9:i, 7ssd:i, 7ssl:i, 7ssn:i, 7sso:i, 7ssw:i, 7st2:i, 7st6:i, 7st7:i, 7tos:L11, 4u1u:BI, 4u1u:DI, 4u1v:BI, 4u1v:DI, 4u20:BI, 4u20:DI, 4u24:BI, 4u24:DI, 4u25:BI, 4u25:DI, 4u26:BI, 4u26:DI, 4u27:BI, 4u27:DI, 5u4i:J, 6u48:CJ, 5u9f:11, 5u9g:11, 7ug7:LK, 8upo:Y, 8upr:Y, 8uql:Y, 8uqm:Y, 8uqp:Y, 8ur0:Y, 8urh:Y, 8uri:Y, 8urx:Y, 8ury:Y, 4uy8:I, 5uyk:11, 5uyl:11, 5uym:11, 5uyn:11, 5uyp:11, 5uyq:11, 4v4h:BI, 4v4h:DI, 4v4q:BI, 4v4q:DI, 4v4v:BG, 4v4w:BG, 4v50:BI, 4v50:DI, 4v52:BI, 4v52:DI, 4v53:BI, 4v53:DI, 4v54:BI, 4v54:DI, 4v55:BI, 4v55:DI, 4v56:BI, 4v56:DI, 4v57:BI, 4v57:DI, 4v5b:AI, 4v5b:CI, 4v5h:BI, 4v5y:BI, 4v5y:DI, 4v64:BI, 4v64:DI, 4v65:B5, 4v66:B5, 4v69:BI, 4v6c:BI, 4v6c:DI, 4v6d:BI, 4v6d:DI, 4v6e:BI, 4v6e:DI, 4v6k:AJ, 4v6l:BJ, 4v6m:BI, 4v6n:AK, 4v6o:BK, 4v6p:BK, 4v6q:BK, 4v6r:BK, 4v6s:AK, 4v6t:BI, 4v6v:BK, 4v6y:BI, 4v6z:BI, 4v70:BI, 4v71:BI, 4v72:BI, 4v73:BI, 4v74:BI, 4v75:BI, 4v76:BI, 4v77:BI, 4v78:BI, 4v79:BI, 4v7a:BI, 4v7b:BI, 4v7c:BK, 4v7d:AK, 4v7i:AI, 4v7s:BI, 4v7s:DI, 4v7t:BI, 4v7t:DI, 4v7u:BI, 4v7u:DI, 4v7v:BI, 4v7v:DI, 4v85:BI, 4v89:BI, 4v9c:BI, 4v9c:DI, 4v9d:CI, 4v9d:DI, 4v9o:AI, 4v9o:CI, 4v9o:EI, 4v9o:GI, 4v9p:AI, 4v9p:CI, 4v9p:EI, 4v9p:GI, 8vs9:L11, 8vsa:L11, 8w51:J, 5wdt:I, 6wd0:i, 6wd1:i, 6wd2:i, 6wd3:i, 6wd4:i, 6wd5:i, 6wd6:i, 6wd7:i, 6wd8:i, 6wd9:i, 6wda:i, 6wdb:i, 6wdc:i, 6wdd:i, 6wde:i, 6wdf:i, 6wdg:i, 6wdh:i, 6wdi:i, 6wdj:i, 6wdk:i, 6wdl:i, 6wdm:i, 5we4:I, 5we6:I, 4wf1:BI, 4wf1:DI, 5wf0:I, 5wfk:I, 5wfs:I, 6wnt:i, 6wnv:i, 6wnw:i, 4woi:BI, 4woi:CI, 4www:RI, 4www:YI, 6xz7:I, 6xza:I2, 6xzb:I2, 4ybb:CJ, 4ybb:DJ, 7yla:Q, 6ysr:I, 6yss:I, 6yst:I, 6ysu:I, 6ztj:BJ
6 5d8b:G 147 128 0.3333 0.3673 0.4219 2.26e-28 5a9z:AJ, 5aa0:AJ, 6c5l:BK, 6c5l:DK, 3cjt:B, 3cjt:F, 3cjt:J, 3cjt:N, 5d8b:CB, 6gsl:48, 5hau:1K, 5hau:2K, 5imq:3, 5imr:3, 5j8b:K, 4v4x:BL, 4v4y:BL, 4v4z:BL, 4v5e:BK, 4v5e:DK, 4v5f:BK, 4v5f:DK, 4v5j:BK, 4v5j:DK, 4v5m:BK, 4v5n:BK, 4v67:BK, 4v67:DK, 4v68:BL, 4v6f:DL, 4v9h:BK, 4v9j:BK, 4v9j:DK, 4v9k:BK, 4v9k:DK, 4v9l:BK, 4v9l:DK, 4v9m:BK, 4v9m:DK, 4v9n:BK, 4v9n:DK, 4w29:BK, 4w29:DK, 4w2e:K, 4wpo:AL, 4wpo:CL, 4wqf:AL, 4wqf:CL, 4wqu:AL, 4wqu:CL, 4wqy:AL, 4wqy:CL, 4xej:AL11, 4xej:BL11, 5zlu:f
7 6spb:I 140 127 0.3272 0.3786 0.4173 5.59e-27 6spd:I, 6spf:I, 6spg:I, 7unr:J, 7unu:J, 7unv:J, 7unw:J
8 3j3v:6 141 130 0.3333 0.3830 0.4154 9.59e-24 7aqc:I, 7aqd:I, 7as8:K, 7as9:K, 7asa:K, 1c04:C, 1hc8:A, 1hc8:B, 3j3w:6, 3j9w:BK, 7o5b:q, 7ope:K, 1qa6:A, 1qa6:B, 7qgu:I, 7qh4:I, 1y39:A, 1y39:B
9 5d8h:C 158 128 0.3086 0.3165 0.3906 2.48e-23 5dar:C, 5dar:F
10 8fmw:AK 139 129 0.3210 0.3741 0.4031 3.46e-23 8fn2:K
11 8a57:E 140 130 0.3333 0.3857 0.4154 9.18e-23 8uu8:H
12 4v4n:AH 134 125 0.2963 0.3582 0.3840 1.07e-22 4v6u:BH
13 3cf5:F 144 127 0.2901 0.3264 0.3701 3.47e-22 3dll:F, 5dm6:F, 5dm7:F, 4io9:F, 4ioa:F, 4ioc:F, 5jvg:F, 3pio:F, 3pip:F, 1sm1:G, 4v49:BG, 4v4a:BG, 4v4g:BJ, 4v4g:DJ, 4v4g:FJ, 4v4g:HJ, 4v4g:JJ, 1xbp:G, 2zjp:F, 2zjq:F, 2zjr:F
14 6dzi:J 133 127 0.3025 0.3684 0.3858 1.18e-21 6dzp:J, 8fr8:S, 8kab:J, 5o60:J, 5o61:J, 7s0s:K, 8v9j:J, 8v9k:J, 8v9l:J, 7xam:J, 8xz3:J, 7y41:J, 5zeb:J, 5zep:J, 5zet:J
15 4v61:BK 145 127 0.2963 0.3310 0.3780 4.79e-21 5mmi:J, 5mmm:J
16 6z1p:An 158 127 0.2593 0.2658 0.3307 7.08e-20
17 7ood:h 128 128 0.2778 0.3516 0.3516 1.31e-17 7p6z:h, 7pah:h, 7pai:h, 7paj:h, 7pak:h, 7pal:h, 7pam:h, 7pan:h, 7pao:h, 7paq:h, 7par:h, 7pas:h, 7pat:h, 7pau:h, 7ph9:h, 7pha:h, 7phb:h, 7phc:h, 7pi8:h, 7pi9:h, 7pia:h, 7pib:h, 7pic:h, 7pio:h, 7pip:h, 7piq:h, 7pir:h, 7pis:h, 7pit:h
18 3cjq:B 121 128 0.2654 0.3554 0.3359 9.97e-17 3cjq:E, 3cjq:H
19 7aih:E 326 134 0.2716 0.1350 0.3284 2.13e-12 7am2:E, 7ane:E
20 4v9f:I 145 127 0.2222 0.2483 0.2835 5.36e-12 3cc2:I, 3cc4:I, 3cc7:I, 3cce:I, 3ccj:I, 3ccl:I, 3ccm:I, 3ccq:I, 3ccr:I, 3ccs:I, 3ccu:I, 3ccv:I, 3cd6:I, 3cma:I, 3cme:I, 3g4s:I, 3g6e:I, 3g71:I, 3i55:I, 3i56:I, 2otj:I, 2otl:I, 2qa4:I, 2qex:I, 1s72:I, 1vq4:I, 1vq5:I, 1vq6:I, 1vq7:I, 1vq8:I, 1vq9:I, 1vqk:I, 1vql:I, 1vqm:I, 1vqn:I, 1vqo:I, 1vqp:I, 1yhq:I, 1yi2:I, 1yij:I, 1yit:I, 1yj9:I, 1yjn:I, 1yjw:I
21 6hiv:AK 323 129 0.2593 0.1300 0.3256 5.94e-12 6hix:AK
22 8cf5:Ee 160 123 0.2099 0.2125 0.2764 0.021 8aaf:z, 8agt:z, 8agu:z, 8agv:z, 8agw:z, 8agx:z, 8agz:z, 8ccs:Ee, 8cdl:Ee, 8cdr:Ee, 8ceh:Ee, 8cg8:Ee, 8cgn:Ee, 8civ:Ee, 8cku:Ee, 8cmj:Ee, 5dge:m2, 5dgf:m2, 6gq1:P2, 6gqb:P2, 6gqv:P2, 8hfr:KM, 3j16:H, 3j77:62, 3j78:62, 5jcs:K, 5juo:P, 5jup:P, 5jus:P, 5jut:P, 5juu:P, 8k2d:LK, 8k82:LK, 6oig:s, 7osa:uL11, 7osm:uL11, 6r84:P, 6r86:P, 6r87:P, 7rr5:P2, 5tgm:m2, 7ug6:q, 7uoo:8, 7uqb:8, 7uqz:8, 7v08:8, 4v4b:BK, 4v6i:BJ, 4v7h:BK, 4v7r:DL, 6xiq:P2, 8y0u:P2, 6ylg:q, 6ylh:q, 7z34:a
23 8c3a:12 63 44 0.1111 0.2857 0.4091 0.024 8cq7:12, 8cqw:12, 8cre:12
24 8idt:y 165 123 0.1914 0.1879 0.2520 0.78 7a01:M2, 5a8l:G, 5aj0:Aq, 9bdn:AL12, 9bdp:AL12, 8bhf:f1, 8bpo:r2, 8btk:Bt, 6d90:t, 6d9j:t, 9f1b:Bt, 9f1c:Bt, 9f1d:Bt, 8fkr:BA, 8fks:BA, 8fkt:BA, 8fku:BA, 8fkv:BA, 8fkw:BA, 8fkx:BA, 8fky:BA, 8fkz:BA, 8fl0:BA, 8fl2:BA, 8fl3:BA, 8fl4:BA, 8fl6:BA, 8fl7:BA, 8fl9:BA, 8fla:BA, 8flb:BA, 8flc:BA, 6frk:4, 6ftg:t, 6fti:t, 6ftj:t, 8g5z:LK, 8g60:LK, 8g6j:LK, 6gz3:Aq, 6gz4:Aq, 6gz5:Aq, 6hcf:t3, 6hcj:u3, 6hcm:t3, 6hcq:u3, 8idy:y, 8ine:y, 8inf:y, 8ink:y, 8ipd:y, 8ipx:y, 8ipy:y, 8ir1:y, 8ir3:y, 3j7p:K, 3j92:t, 3jag:t, 3jah:t, 3jai:t, 3jaj:K, 3jan:K, 8k2c:Lt, 7ls1:k, 7ls2:k, 5lzs:t, 5lzt:t, 5lzu:t, 5lzv:t, 5lzw:t, 5lzx:t, 5lzy:t, 5lzz:t, 6mtd:t, 6mte:t, 7nwg:u3, 7nwh:t, 7nwi:t, 7o7y:Bt, 7o7z:Bt, 7o80:Bt, 7o81:Bt, 6olg:Aq, 8p2k:Bt, 8q87:Bt, 6r5q:t, 6r6g:t, 6r6p:t, 6r7q:t, 8scb:t, 6sgc:t2, 6t59:t3, 4v5z:Bi, 4v6x:CK, 8xsx:LK, 8xsy:Lt, 8xsz:Lt, 8yoo:Lt, 8yop:Lt, 6zm7:Lt, 6zme:Lt, 6zmi:Lt, 6zmo:Lt, 6zvk:M2
25 3g2s:A 146 62 0.1235 0.1370 0.3226 3.4 3g2s:B, 3g2t:A, 3g2t:B, 3g2u:A, 3g2u:B, 3g2v:A, 3g2v:B, 3g2w:A, 3g2w:B, 1jwg:A, 1jwg:B, 1py1:A, 1py1:B, 1py1:C, 1py1:D, 1ujj:A, 1ujk:A, 1ujk:B
26 6g9f:A 539 21 0.0679 0.0204 0.5238 4.1 6g9s:A
27 8arv:A 255 93 0.1481 0.0941 0.2581 5.3 8arv:B
28 7s37:P 1033 34 0.0802 0.0126 0.3824 5.4 7s3h:P
29 8v6g:A 1050 77 0.1420 0.0219 0.2987 8.1 8v6h:A, 8v6i:A, 8v6j:A
30 8g99:A 1063 77 0.1420 0.0216 0.2987 8.2 8g9f:A, 8g9l:A, 8g9n:A, 8g9o:A, 8ucu:A, 8ucv:A, 8ucw:A, 8v5m:A, 8v5n:A, 8v5o:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218