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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AMKMSELEKMLKGEHFDGASAEIEALRSQAGRLKLEINQSLDEAERYALQRELFGHLGHKSCVQPPFHCEFGKTIRIGDH
TFINMNVVMLDGAPITIGDHVLIGPSTQFYTASHSLDYRRRQAWETICKPIVIEDDVWIGGNVVINQGVTIGARSVVAAN
SVVNQDVPPDTLVGGTPARILRSLK

The query sequence (length=185) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3nz2:J 185 185 1.0000 1.0000 1.0000 1.72e-139 3ect:A, 3nz2:A, 3nz2:C, 3nz2:B, 3nz2:D, 3nz2:E, 3nz2:F, 3nz2:G, 3nz2:H, 3nz2:I, 3nz2:K, 3nz2:L
2 3igj:C 188 188 0.3730 0.3670 0.3670 5.43e-41 3igj:A, 3igj:B
3 4isx:A 186 184 0.3676 0.3656 0.3696 4.54e-40 4isx:B
4 1kru:A 201 185 0.3405 0.3134 0.3405 1.88e-36 1kqa:A, 1kqa:B, 1kqa:C, 1krr:A, 1krr:B, 1krr:C, 1kru:B, 1kru:C, 1krv:A, 1krv:C, 1krv:B
5 5u2k:A 190 184 0.3514 0.3421 0.3533 4.98e-36 5v0z:A, 5v0z:C, 5v0z:B, 3v4e:A, 3v4e:C, 3v4e:B
6 3r8y:A 203 108 0.2270 0.2069 0.3889 7.78e-11 3r8y:C, 3r8y:D, 3r8y:F
7 4hus:A 212 109 0.2054 0.1792 0.3486 9.70e-11 4hur:A, 4hur:B, 4hur:C, 4hus:C, 6x3c:A, 6x3c:F, 6x3c:B, 6x3c:C, 6x3c:D, 6x3c:E, 6x3j:A, 6x3j:B, 6x3j:D, 6x3j:C, 6x3j:E, 6x3j:F
8 1khr:A 206 51 0.1459 0.1311 0.5294 3.37e-09 3dho:A, 3dho:C, 3dho:B, 3dho:D, 3dho:F, 3dho:E, 1khr:B, 1khr:C, 1khr:D, 1khr:E, 1khr:F, 1kk4:A, 1kk4:B, 1kk4:C, 1kk4:D, 1kk4:E, 1kk4:F, 1mr9:A, 1mr9:C, 1mr9:B, 1mr9:X, 1mr9:Z, 1mr9:Y, 1mrl:A, 1mrl:B, 1mrl:C
9 3mqg:C 192 110 0.2054 0.1979 0.3455 1.79e-08 3mqg:A, 3mqg:B, 3mqg:D, 3mqg:E, 3mqg:F, 3mqh:A, 3mqh:C, 3mqh:B, 3mqh:D, 3mqh:F, 3mqh:E
10 7s3u:A 145 102 0.1730 0.2207 0.3137 6.23e-08 7s3w:A, 7s41:A, 7s42:A, 7s43:A, 7s44:A, 7s45:A
11 7s3u:A 145 25 0.0757 0.0966 0.5600 8.6 7s3w:A, 7s41:A, 7s42:A, 7s43:A, 7s44:A, 7s45:A
12 4mzu:F 294 106 0.2000 0.1259 0.3491 1.46e-07 4mzu:A, 4mzu:C, 4mzu:E, 4mzu:B, 4mzu:D, 4mzu:G, 4mzu:I, 4mzu:K, 4mzu:H, 4mzu:J, 4mzu:L, 4zu4:A, 4zu4:B, 4zu4:C
13 8j40:A 209 51 0.1135 0.1005 0.4118 1.50e-07
14 8vr7:E 180 49 0.1297 0.1333 0.4898 3.72e-07 8vr6:A, 8vr7:A, 8vr7:B, 8vr7:C, 8vr7:D, 8vr7:F
15 6pub:A 210 51 0.1189 0.1048 0.4314 1.21e-06 6u9c:A, 6u9c:B, 6u9c:C
16 2xat:A 208 51 0.1027 0.0913 0.3725 1.90e-05
17 7uuk:C 276 56 0.1189 0.0797 0.3929 2.76e-05 7jm1:A, 7jm1:C, 7jm1:B, 7jm2:A, 7jm2:C, 7jm2:B, 7uuj:A, 7uuj:C, 7uuj:B, 7uuk:A, 7uuk:B, 7uul:A, 7uul:B, 7uul:D, 7uul:C, 7uul:F, 7uul:E, 7uum:A, 7uun:A, 7uuo:B
18 6wye:A 261 54 0.1351 0.0958 0.4630 2.81e-05 7ra4:A, 7ra4:C, 7ra4:B, 6wye:C, 6wye:B, 6wye:D, 6wye:F, 6wye:E
19 7aqq:z 233 117 0.1784 0.1416 0.2821 2.83e-05 7a23:q, 7a23:p, 7a24:q, 7a24:p, 7ar7:z, 7ar8:z, 7arb:z, 8bef:z, 8bpx:z, 8bq5:z, 8bq6:z
20 7aqq:y 268 121 0.1676 0.1157 0.2562 3.43e-05 7ar7:y, 7ar8:y, 7arb:y, 8bef:y, 8bpx:y, 8bq5:y, 8bq6:y
21 1hm8:A 458 73 0.1189 0.0480 0.3014 1.62e-04 4aaw:A, 4ac3:A, 1g97:A, 1hm8:B, 1hm9:A, 1hm9:B, 7kr9:A
22 8e73:G2 258 117 0.1730 0.1240 0.2735 2.77e-04 6x89:G2
23 2wle:C 211 55 0.1027 0.0900 0.3455 2.83e-04 2wle:A, 2wle:B, 2wlf:A, 2wlf:C, 2wlf:B, 2wlg:A, 2wlg:C, 2wlg:B
24 3vnp:A 171 128 0.1838 0.1988 0.2656 2.87e-04 3vnp:B, 3vnp:C
25 7txp:A 209 111 0.1568 0.1388 0.2613 6.82e-04 7txq:A, 7txs:A
26 4n27:A 175 105 0.1514 0.1600 0.2667 0.001 4n27:B, 4n27:C, 4n27:D, 4n27:E, 4n27:F
27 4n69:A 243 49 0.1189 0.0905 0.4490 0.002 4n69:B, 4n6b:A, 4n6b:E, 4n6b:B, 4n6b:C, 4n6b:D, 4n6b:F
28 4h7o:A 258 49 0.1081 0.0775 0.4082 0.002 4h7o:C, 4h7o:B
29 6sc4:B 178 125 0.1730 0.1798 0.2560 0.003 6sc4:A, 6sc4:C, 6sc4:D, 6sc4:E
30 1t3d:A 262 49 0.1081 0.0763 0.4082 0.004 7e3y:A, 7e3y:C, 7e3y:B, 8i04:A, 8i04:C, 8i04:B, 8i06:A, 8i06:B, 8i09:A, 8i09:B, 8i09:C, 8i09:D, 8i09:E, 8i09:F, 8i09:G, 8i09:H, 8i09:I, 8i09:J, 8i09:K, 8i09:L, 6jvu:A, 6jvu:C, 6jvu:B, 6jvu:D, 6jvu:F, 6jvu:E, 1t3d:B, 1t3d:C
31 7l7y:AAA 217 55 0.1135 0.0968 0.3818 0.005 7l7z:AAA, 7l81:AAA, 7l82:AAA
32 2fko:A 173 114 0.1676 0.1792 0.2719 0.005 1v3w:A, 1v67:A
33 2fko:A 173 67 0.1081 0.1156 0.2985 0.15 1v3w:A, 1v67:A
34 6pxa:E 221 38 0.0757 0.0633 0.3684 0.012 6pxa:A, 6pxa:B, 6pxa:C, 6pxa:D, 6pxa:F, 6pxa:G, 6pxa:H, 6pxa:I, 6pxa:J, 6pxa:K, 6pxa:L, 5ux9:A, 5ux9:B, 5ux9:C, 5ux9:D
35 8bef:x 210 61 0.1027 0.0905 0.3115 0.013 8bpx:x, 8bq5:x, 8bq6:x
36 7ojp:Z 261 107 0.1676 0.1188 0.2897 0.014 5dep:A, 5dep:B, 5dep:D, 5dep:E, 5dep:F, 5dg3:A, 5dg3:B, 5dg3:C, 5dg3:D, 5dg3:E, 7oj6:A, 7oj6:B, 7oj6:C, 7ojp:A, 7ojp:B, 7ojp:C, 7ojp:D, 7ojp:E, 7ojp:F, 7ojp:G, 7ojp:H, 7ojp:I, 7ojp:J, 7ojp:K, 7ojp:L, 7ojp:M, 7ojp:N, 7ojp:O, 7ojp:P, 7ojp:Q, 7ojp:R, 7ojp:S, 7ojp:T, 7ojp:U, 7ojp:V, 7ojp:W, 7ojp:X, 7ojp:Y, 7ojp:a, 7ojp:b, 7ojp:c, 7ojp:d, 7ojq:A, 7ojq:B, 7ojq:C, 7ojw:A, 7ojw:B, 7ojw:C, 7ojy:A, 7ojy:B, 7ojy:C, 7ok1:A, 7ok1:B, 7ok1:C, 7ok2:1, 7ok2:Y, 7ok2:Z, 7ok2:2, 7ok2:4, 7ok2:3, 7ok2:A, 7ok2:B, 7ok2:C, 7ok2:D, 7ok2:E, 7ok2:F, 7ok2:G, 7ok2:I, 7ok2:H, 7ok2:J, 7ok2:L, 7ok2:K, 7ok2:M, 7ok2:N, 7ok2:O, 7ok2:P, 7ok2:Q, 7ok2:R, 7ok2:S, 7ok2:T, 7ok2:U, 7ok2:V, 7ok2:X, 7ok2:W, 7oka:A, 7oka:C, 7oka:B, 7oka:D, 7oka:E, 7oka:F, 7oka:G, 7oka:H, 7oka:I, 7oka:M, 7oka:N, 7oka:O, 7oka:J, 7oka:K, 7oka:L, 7oka:P, 7oka:Q, 7oka:R, 7oka:S, 7oka:T, 7oka:U, 7oka:V, 7oka:W, 7oka:X, 7oka:Y, 7oka:Z, 7oka:a, 7oka:b, 7oka:d, 7oka:c, 7okb:A, 7okb:B, 7okb:C, 7okb:D, 7okb:E, 7okb:F, 7okb:G, 7okb:H, 7okb:I, 7okb:M, 7okb:N, 7okb:O, 7okb:J, 7okb:K, 7okb:L, 7okb:P, 7okb:Q, 7okb:R, 7okb:S, 7okb:T, 7okb:U, 7okb:V, 7okb:W, 7okb:X, 7okb:Y, 7okb:Z, 7okb:a, 7okb:b, 7okb:c, 7okb:d, 7t5r:A, 7t5r:B, 7t5r:C, 7t5r:D, 7t5r:F, 7t5r:E, 7t5s:A, 7t5s:B, 7t5s:C, 7t5s:D, 7t5s:F, 7t5s:E, 7t5x:A, 7t5x:B, 7t5x:C, 7t5x:D, 7t5x:F, 7t5x:E, 7t5z:A, 7t5z:B, 7t5z:C, 7t5z:D, 7t5z:E, 7t5z:F, 7t60:A, 7t60:B, 7t60:C, 7t60:D, 7t60:F, 7t60:E, 7t61:A, 7t61:B, 7t61:C, 7t61:D, 7t61:E, 7t61:F, 6uee:A, 6uee:C, 6uee:B, 6uee:D, 6uee:E, 6uee:F, 6ueg:A, 6ueg:C, 6ueg:B, 6ueg:D, 6ueg:E, 6ueg:F
37 4hzd:A 250 49 0.1081 0.0800 0.4082 0.017 4hzc:F, 4hzc:J
38 6ive:A 168 55 0.1081 0.1190 0.3636 0.021 6ive:B, 6ive:C, 6ive:D, 6ive:E, 6ive:F
39 3fsb:A 260 47 0.0973 0.0692 0.3830 0.025 3fs8:A, 3fs8:B, 3fsb:B, 3fsc:A, 3fsc:B
40 3gvd:I 272 49 0.1027 0.0699 0.3878 0.026 3gvd:A, 3gvd:C, 3gvd:B, 3gvd:D, 3gvd:F, 3gvd:E, 3gvd:G, 3gvd:H, 3gvd:J, 3gvd:K, 3gvd:L
41 4eaa:A 210 33 0.0919 0.0810 0.5152 0.036 4ea7:A, 4ea8:A, 4ea9:A, 4eab:A
42 7okc:A 264 53 0.1027 0.0720 0.3585 0.042 2aq9:A, 6hy2:X, 4j09:A, 2jf3:A, 6p9p:A, 6p9q:A, 6p9r:A, 6p9s:A, 6p9t:A, 2qia:A, 2qiv:X
43 3i3a:A 259 51 0.0919 0.0656 0.3333 0.046 3i3a:B, 3i3a:C, 3i3x:A, 3i3x:B, 3i3x:C
44 8gpm:A 193 94 0.1351 0.1295 0.2660 0.12 8gpp:A, 8gpp:B, 8gpp:C
45 2iu8:A 346 78 0.1351 0.0723 0.3205 0.12 2iu8:B, 2iu8:C, 2iu9:A, 2iu9:B, 2iu9:C, 2iua:A, 2iua:C
46 4ll2:B 224 27 0.0811 0.0670 0.5556 0.16 4oei:A, 4oei:B, 3s18:A, 3s18:B, 3v6n:A, 3v6n:B, 4yeh:A, 4yeh:B
47 1ssq:D 257 53 0.0973 0.0700 0.3396 0.17 1ssq:A, 1sst:A, 1sst:B, 1sst:C
48 2oi6:B 452 76 0.1243 0.0509 0.3026 0.29 4aa7:A, 4aa7:B, 1fwy:A, 1fwy:B, 1hv9:A, 1hv9:B, 2oi5:A, 2oi5:B, 2oi6:A, 2oi7:A, 2oi7:B, 3twd:A, 3twd:B
49 4eqy:G 260 46 0.0919 0.0654 0.3696 0.30
50 7bw9:A 280 92 0.1351 0.0893 0.2717 0.47 7bw9:B, 7bw9:C
51 4r37:A 255 101 0.1135 0.0824 0.2079 0.80
52 3l8a:B 385 39 0.0541 0.0260 0.2564 1.8 3l8a:A
53 3lp9:A 227 27 0.0703 0.0573 0.4815 2.1 3lp9:B, 3lp9:C, 3lp9:D
54 3mdd:A 385 20 0.0595 0.0286 0.5500 2.1 3mdd:B, 3mde:A, 3mde:B, 1udy:A, 1udy:B, 1udy:C, 1udy:D
55 2a1t:C 388 19 0.0595 0.0284 0.5789 2.1 2a1t:A, 2a1t:B, 2a1t:D, 1egc:A, 1egc:B, 1egc:C, 1egc:D, 1egd:A, 1egd:B, 1egd:C, 1egd:D, 1ege:A, 1ege:B, 1ege:C, 1ege:D, 4p13:A, 4p13:B, 4p13:C, 4p13:D, 8sgp:A, 8sgp:B, 8sgp:C, 8sgp:D, 1t9g:A, 1t9g:B, 1t9g:C, 1t9g:D
56 4fce:A 441 71 0.0973 0.0408 0.2535 2.2
57 3vm5:A 499 32 0.0757 0.0281 0.4375 2.2
58 3d8v:A 478 84 0.1297 0.0502 0.2857 2.4 3dj4:A, 4g3p:A, 4g3q:A, 4g3s:A, 4g87:A, 6ge9:A, 4hcq:A, 4k6r:A, 2qkx:A, 3spt:A, 3st8:A
59 4m99:A 206 57 0.0973 0.0874 0.3158 3.0 4m99:B, 4m99:C
60 6vmb:B 503 31 0.0757 0.0278 0.4516 3.6 6fkf:A, 6fkf:C, 6fkf:E, 6fkh:C, 6fkh:E, 6fkh:A, 6fki:E, 6fki:A, 6fki:C, 1kmh:A, 6vmb:A, 6vmb:C, 6vmd:A, 6vmd:B, 6vmd:C, 6vof:A, 6vof:B, 6vof:C, 6vog:A, 6vog:B, 6vog:C, 6voh:A, 6voh:C, 6voh:B, 6voi:A, 6voi:C, 6voi:B, 6voj:A, 6voj:B, 6voj:C, 6vok:A, 6vok:B, 6vok:C, 6vol:A, 6vol:B, 6vol:C, 6vom:A, 6vom:B, 6vom:C, 6von:A, 6von:B, 6von:C, 6voo:A, 6voo:B, 6voo:C
61 3r3r:A 184 96 0.1405 0.1413 0.2708 4.7
62 3tte:A 361 39 0.1027 0.0526 0.4872 9.3 3toy:A, 3toy:B, 3toy:C, 3toy:D, 3tte:B
63 3oyo:A 225 54 0.0865 0.0711 0.2963 9.8 3oyo:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218