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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AMKKENLKILAKKAQTIAIVGANYRFATRVLLENLDKMDFTGTIYLVNPRYENIDGVRCYQSLLEIEDTIDVVVGLVNPQ
LMIQVASNASKINAKVLVIPGGGYGESGVEGQNIQNAILERAADSGMRIVGPNCMGYLNMHAQFTPYIGTLHRPLRPIKK
GPVSIISQSGSVNDAFIASKLGISKIYSTGNEADVQMHDYLNLLAEDPETSVIILYIEAIRNHLSFLRALDLCSKNKKPV
IAIKVGRTIKSAAVANAHSGALAGDYEIEKLFLEGHGVLFVEDIDQAVAVALLLSQPYLPTVNTVAALTVSGGQAGILLD
LAEDYGVDFPDFSAVTNYEIASKLPELGGLSNPLDIWGKSSKDFSEVSNICLSSIVKDADIGIITVAIDAPIGQGDHEFD
FTSIPAKDLASLRGNSDKPFLYFSHIQTEFDPRVESILDEAGIAVIQGSRNALVACRALFKYKEFLEKNNHTPIYSVEDL
SIQKGLKLLHDNEGRKLLDESGFVSPREQVVTSLQEGVDYAESIGYPVVLKAQGLAHKTDVGGVALNIKSAAKLKKAWGK
MEHLNSPYYLIQEMVTDGFETILAYRTDMNYGPVVIFGLGGIYTELFNEVVLAVPPITHKKAEQMVKSIPMLWKSIEGYR
GNPALDLEALTASIVQMGETAMEKYEEIVEFEINPLSVRVKGVVALDVLASVK

The query sequence (length=693) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7cm9:A 693 693 1.0000 1.0000 1.0000 0.0 7cm9:B, 7cm9:C, 7cm9:D
2 5hbr:A 464 393 0.1659 0.2478 0.2926 5.25e-36 5hbr:C, 4xyl:A, 4xyl:C, 4xym:A, 4xym:C, 4xz3:A, 4xz3:C, 4y8v:A, 4y8v:C, 4yak:A, 4yak:C
3 4xym:B 229 215 0.1039 0.3144 0.3349 1.40e-32 4xym:D, 4xz3:B, 4xz3:D, 4y8v:B, 4y8v:D, 4yb8:B, 4yb8:D, 4ybz:D
4 2d5a:A 142 137 0.0577 0.2817 0.2920 1.04e-09 2e6u:X
5 1y81:A 116 111 0.0519 0.3103 0.3243 1.23e-08
6 3q9n:A 138 103 0.0462 0.2319 0.3107 2.67e-06 3q9n:B, 3q9u:A, 3q9u:B
7 6mgg:C 295 108 0.0491 0.1153 0.3148 0.001 6mgg:A, 6pfn:A, 6pfn:C
8 5l8e:A 517 130 0.0491 0.0658 0.2615 0.004
9 8fxi:C 630 82 0.0390 0.0429 0.3293 0.030 8fxi:D
10 1scu:A 288 183 0.0678 0.1632 0.2568 0.031 1cqi:A, 1cqi:D, 1cqj:A, 1cqj:D, 1jkj:A, 1jkj:D, 1jll:A, 1jll:D, 2nu6:A, 2nu6:D, 2nu7:A, 2nu7:D, 2nu8:A, 2nu8:D, 2nu9:A, 2nu9:D, 2nu9:F, 2nu9:H, 2nua:A, 2nua:D, 1scu:D, 2scu:A, 2scu:D
11 2yw2:A 423 65 0.0303 0.0496 0.3231 0.078 2yw2:B
12 7lgm:A 719 67 0.0289 0.0278 0.2985 0.35 7lgm:B
13 6xru:A 309 132 0.0491 0.1100 0.2576 0.37 5cae:A, 1euc:A, 2fpg:A, 7msr:A, 7mss:A, 7mst:A, 6wcv:A, 4xx0:A
14 4xru:B 394 58 0.0260 0.0457 0.3103 1.9 4xru:E
15 3vpd:A 281 34 0.0188 0.0463 0.3824 3.6 3vpd:B
16 1uc9:A 256 34 0.0188 0.0508 0.3824 3.8 1uc9:B
17 1eyz:A 389 160 0.0592 0.1054 0.2562 4.9 1eyz:B, 1ez1:A, 1ez1:B, 1kj8:A, 1kj8:B, 1kj9:A, 1kj9:B, 1kji:A, 1kji:B, 1kjj:A, 1kjj:B, 1kjq:A, 1kjq:B
18 2r0q:C 193 40 0.0216 0.0777 0.3750 5.5 2r0q:D, 2r0q:E, 2r0q:F
19 8fgw:C 1342 150 0.0606 0.0313 0.2800 6.2 8fh3:C
20 7suk:NB 142 89 0.0361 0.1761 0.2809 9.2 7ajt:UC, 7d5s:5H, 7d5t:5H, 7d63:5H, 6ke6:5H, 6lqp:5H, 6lqq:5H, 6lqr:5H, 6lqs:5H, 6lqt:5H, 6lqu:5H, 6lqv:5H, 5wlc:NB, 7wtl:UC, 6zqa:UC, 6zqb:UC, 6zqc:UC, 6zqf:UC, 6zqg:UC
21 3din:A 816 139 0.0577 0.0490 0.2878 9.3 3din:B, 3jux:A, 4ys0:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218