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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AMHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDV
QWVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPF
KAKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVSDFTGGHNYMLT
GNIVAGNPRVVKAMLANMRDELSDALK

The query sequence (length=267) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6ib8:B 270 267 1.0000 0.9889 1.0000 0.0 6ib7:A, 6ib8:A, 2qfl:A, 6tqn:T, 6tqn:S, 6tqo:T, 6tqo:S
2 8wdq:A 273 271 0.5543 0.5421 0.5461 2.57e-101 8wdq:B
3 3lv0:A 258 246 0.4045 0.4186 0.4390 3.64e-64 3luz:A, 3lv0:B
4 3luz:B 234 246 0.3783 0.4316 0.4106 1.31e-54
5 2p3n:A 256 246 0.3483 0.3633 0.3780 2.11e-48 2p3n:B, 2p3n:C, 2p3n:D
6 6giu:A 275 257 0.3146 0.3055 0.3268 3.16e-45 4as4:A, 4as4:B, 1awb:A, 1awb:B, 6giu:B, 6gj0:A, 6gj0:B, 2hhm:A, 2hhm:B, 1ima:A, 1ima:B, 1imb:A, 1imb:B, 1imc:A, 1imc:B, 1imd:A, 1imd:B, 1ime:A, 1ime:B, 6zk0:AAA, 6zk0:BBB
7 2czi:A 259 251 0.3184 0.3282 0.3386 9.90e-44 2czh:B
8 4as5:A 274 249 0.3034 0.2956 0.3253 1.58e-42 4as5:B, 4as5:C, 4as5:D
9 2bji:A 274 259 0.3146 0.3066 0.3243 1.50e-40 2bji:B
10 5dw8:A 260 217 0.2921 0.3000 0.3594 1.40e-36 5dw8:B, 5j16:A, 5j16:B, 5j16:C, 5j16:D
11 5eyg:B 265 183 0.1985 0.2000 0.2896 1.08e-23 5eyg:A, 5eyh:A, 5eyh:B, 5f24:A, 5f24:B, 4g61:A, 4g61:B, 4i3e:A, 4i3e:B, 4i3y:A, 4i3y:B, 4i40:A, 4i40:B, 4ptk:A, 4ptk:B, 3ryd:A, 3ryd:C
12 5eq9:B 260 231 0.2472 0.2538 0.2857 3.16e-21 5eq8:A, 5eq9:A, 5eq9:C, 5eq9:D, 5t3j:A
13 1dk4:A 252 194 0.2022 0.2143 0.2784 2.46e-17 1dk4:B, 1g0h:A, 1g0h:B, 1g0i:A, 1g0i:B
14 5zon:A 256 202 0.2247 0.2344 0.2970 1.55e-13 5yht:A, 5yht:B, 5zon:B, 5zon:C, 5zon:D
15 6b5z:A 252 229 0.2622 0.2778 0.3057 2.77e-13 6b5z:B, 6b60:A, 6b60:B, 6b61:A, 6b61:B, 6b62:A, 6b62:B, 6b63:A, 6b63:B, 6b64:A, 6b64:B, 6b65:A, 6b65:B, 6b66:A, 6b66:B, 1lbx:A, 1lbx:B, 1lby:A, 1lby:B, 1lbz:A, 1lbz:B
16 4hxv:A 317 206 0.2060 0.1735 0.2670 2.92e-09 4o7i:A
17 8f9y:A 352 288 0.2734 0.2074 0.2535 1.92e-08
18 2wef:A 303 264 0.2509 0.2211 0.2538 2.78e-08 1jp4:A
19 1k9y:A 354 357 0.2959 0.2232 0.2213 1.96e-06 1k9z:A, 1ka0:A, 1ka1:A, 1qgx:A
20 5djj:A 257 87 0.0936 0.0973 0.2874 0.017 5djg:A, 5djh:A, 5dji:A, 5djk:A
21 5q0c:A 328 86 0.0861 0.0701 0.2674 0.13 5et6:A, 5et6:C, 5et6:B, 5et6:D, 4he0:A, 4he1:A, 4he2:A, 3ifa:A, 3ifa:B, 3ifa:C, 3ifa:D, 3ifc:A, 3ifc:B, 3ifc:C, 3ifc:D, 5k56:A, 5l0a:A, 5q0c:B, 5q0c:C, 5q0c:D, 5q0c:E, 5q0c:F, 5q0c:G, 5q0c:H
22 8de5:A 338 126 0.1386 0.1095 0.2937 0.33
23 5o9z:L 459 41 0.0562 0.0327 0.3659 1.9
24 2wnb:A 273 126 0.1049 0.1026 0.2222 2.3 2wnf:A
25 1ee9:A 317 64 0.0712 0.0599 0.2969 2.9
26 4oal:A 444 61 0.0524 0.0315 0.2295 2.9 4oal:B
27 9enp:A 1072 135 0.1461 0.0364 0.2889 3.3 9enq:A, 8oja:A
28 8v1t:A 1064 147 0.1573 0.0395 0.2857 4.1
29 5k55:A 290 65 0.0562 0.0517 0.2308 4.5 5et8:A
30 5fm6:A 426 40 0.0562 0.0352 0.3750 4.8 5fm7:A, 4ww4:A
31 8av6:C 459 40 0.0562 0.0327 0.3750 5.2 8av6:A, 8av6:B, 6fhs:A, 6fhs:B, 6fhs:C, 6fml:A, 6fml:B, 6fml:C, 8oo7:A, 8oo7:B, 8oo7:C, 8ooc:A, 8ooc:B, 8ooc:C, 8oop:A, 8oop:B, 8oop:C, 8oor:A, 8oor:B, 8oor:C, 4wvy:A
32 5yjl:B 415 69 0.1011 0.0651 0.3913 5.2 5yjl:A
33 8v1q:A 1097 149 0.1573 0.0383 0.2819 6.2 8exx:A, 7luf:A, 7luf:B, 8oj6:A, 8oj7:A, 8ojb:A, 8ojd:A, 8v1r:A, 8v1s:A, 8vq2:A, 8vq2:B
34 3e4d:A 278 19 0.0375 0.0360 0.5263 7.0 3e4d:B, 3e4d:C, 3e4d:E, 3e4d:D, 3e4d:F
35 3ojl:A 418 84 0.0749 0.0478 0.2381 9.9 3ojl:B, 3ojo:A, 3ojo:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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