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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AMGSRVVILFTDIEESTALNERIGDRAWVKLISSHDKLVSDLVRRQSGHVVKSQGDGFMVAFARPEQAVRCGIELQRALR
RNEEIRVRIGIHMGRSVRRGDDLFGRNVAMAARVAAQAAGGEILVSQPVRDALSRSDGIRFDDGREVELKGFSGTYRLFA
VLA

The query sequence (length=163) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4wp8:B 166 168 0.9816 0.9639 0.9524 3.89e-108 5d0e:A, 5d0e:B, 5d0g:A, 5d0g:B, 5d0h:A, 5d0h:B, 5d15:A, 5d15:B, 4wp8:A, 4wp9:A, 4wp9:B, 4wpa:A, 4wpa:B
2 1ybu:A 166 160 0.3804 0.3735 0.3875 8.36e-25 1ybu:D
3 1fx4:A 231 184 0.3374 0.2381 0.2989 7.79e-15
4 1y10:C 363 158 0.2883 0.1295 0.2975 3.77e-10 2ev1:A, 2ev1:B, 2ev2:A, 2ev2:B, 2ev3:A, 2ev3:B, 2ev4:A, 2ev4:B, 1y10:A, 1y10:B, 1y10:D
5 6fht:B 735 170 0.2761 0.0612 0.2647 8.02e-10 5ajg:A, 8avv:A, 8avv:B, 8avx:A, 8avx:B, 8bor:A, 8bor:B, 8bor:C, 8bor:D, 8c3i:B, 8c3i:A, 5c5k:A, 5c5k:B, 5c5k:C, 5c5k:D, 4cqh:A, 6fht:A, 6ftd:A, 6ftd:B, 4ijg:A, 5k5b:A, 5l8m:A, 5lbr:A, 5mg0:A, 5mg1:A, 5nfx:A, 5nm3:A, 5nm3:B, 5nm3:C, 5nm3:D, 5nwn:A, 5nwn:B, 5nwn:C, 5nwn:D, 4o01:A, 4o01:B, 4o01:C, 4o01:D, 4o0p:A, 4o0p:B, 4o8g:A, 2o9b:A, 2o9c:A, 4q0h:A, 4q0i:A, 4q0j:A, 3s7n:A, 3s7o:A, 3s7p:A, 3s7q:A, 8sgk:A, 8sgk:B, 6t3l:B, 6t3l:A, 6t3u:B, 6t3u:A, 4y3i:A, 4y5f:A, 4z1w:A, 7z9d:A, 7z9e:A, 4zrr:A, 1ztu:A
6 1wc4:A 199 180 0.3006 0.2462 0.2722 0.001 2bw7:A, 2bw7:B, 2bw7:C, 2bw7:D, 1wc0:A, 1wc0:B, 1wc1:A, 1wc1:C, 1wc1:B, 1wc3:A, 1wc3:B, 1wc4:B, 1wc5:A, 1wc5:D, 1wc5:B, 1wc5:C, 1wc6:A, 1wc6:C, 1wc6:B
7 8bv5:A 437 158 0.2147 0.0801 0.2215 0.002
8 4yut:A 351 178 0.2577 0.1197 0.2360 0.083 8qfe:A, 8qff:A, 8qfg:A, 8qfh:A, 8qfi:A, 8qfj:A, 5x4t:A, 5x4u:A, 5x4v:A, 4yus:A, 4yut:B
9 4o7p:B 451 79 0.1411 0.0510 0.2911 0.62
10 6pas:B 576 132 0.2025 0.0573 0.2500 0.89 6pat:B
11 4ijs:A 232 46 0.0736 0.0517 0.2609 1.1 4ijs:B, 4ijs:C, 4ijs:D, 3zla:A, 3zla:B, 3zla:C, 3zla:D, 3zla:E, 3zla:F, 3zla:G, 3zla:H
12 4urs:A 162 108 0.1656 0.1667 0.2500 1.8 4urg:A, 4urs:B
13 7y4l:MI 275 38 0.0859 0.0509 0.3684 1.9 7ezx:MA, 7ezx:MG, 7ezx:MN, 7ezx:MQ, 6kgx:M1, 6kgx:21, 6kgx:M4, 6kgx:24, 7y4l:ZI, 7y4l:M9, 7y4l:Z9, 7y5e:Z9, 7y5e:M5, 7y5e:Z5, 7y5e:M9, 7y7a:MH, 7y7a:ZH, 7y7a:Ma, 7y7a:Mf, 7y7a:Za, 7y7a:Zf, 7y7a:Mh, 7y7a:Zh
14 4o27:A 325 54 0.0920 0.0462 0.2778 2.1 4fzd:A, 1upk:A
15 4jwt:A 245 93 0.1227 0.0816 0.2151 4.0
16 6yx5:B 339 42 0.1166 0.0560 0.4524 4.3
17 6top:A 154 58 0.1227 0.1299 0.3448 4.5 6top:B, 6top:C, 6top:D
18 8pfg:P 136 75 0.1104 0.1324 0.2400 9.4 5ond:A, 5ond:B, 8pib:P

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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