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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKACQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVMR
FSETEQNGKLEWLIRKDGCMHCEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKCT
LCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEGVGGTHVMYVLHHADQPELYHGLP
KDPKIDTSVSLWKGALKPLAAAGFIATFAGLIFHYIGIGPNKEVDDDEE

The query sequence (length=289) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1kqf:B 289 289 1.0000 1.0000 1.0000 0.0 1kqg:B
2 1h0h:B 214 211 0.2526 0.3411 0.3460 2.14e-38 1h0h:L
3 8bqg:B 214 211 0.2630 0.3551 0.3602 1.77e-37 8bqh:B, 8bqi:B, 8bqj:B, 8bqk:B, 8bql:B, 8cm4:B, 8cm4:D, 8cm5:B, 8cm5:D, 8cm5:L, 8cm5:S, 8cm6:B, 8cm6:D, 8cm7:B, 8rc8:B, 8rc9:B, 8rca:B, 8rcb:B, 8rcc:B, 8rcg:B, 6sdr:B, 6sdv:B, 7z5o:BBB
4 2vpw:F 193 197 0.2457 0.3679 0.3604 7.17e-27 2vpw:B, 2vpx:F, 2vpx:B, 2vpy:F, 2vpy:B, 2vpz:F, 2vpz:B
5 5ch7:B 329 184 0.2007 0.1763 0.3152 2.62e-16 5ch7:D, 5ch7:F, 5chc:B, 5chc:D, 5chc:F, 5e7o:B, 5e7o:D, 5e7o:F, 5e7o:H, 5e7o:J, 5e7o:L, 4ydd:B, 4ydd:D, 4ydd:F
6 7qv7:B 183 174 0.2076 0.3279 0.3448 5.48e-15 7qv7:C, 7qv7:J, 7qv7:N, 7qv7:P, 7qv7:X
7 6f0k:B 961 203 0.1903 0.0572 0.2709 1.47e-13
8 8k9e:B 951 226 0.2111 0.0641 0.2699 2.34e-13 8k9f:B, 8x2j:B
9 2ivf:B 337 247 0.2076 0.1780 0.2429 4.93e-13
10 8c0z:C 158 153 0.1453 0.2658 0.2745 1.56e-12 8c0z:F
11 8c0z:C 158 99 0.0865 0.1582 0.2525 9.4 8c0z:F
12 3egw:B 509 87 0.1038 0.0589 0.3448 1.63e-11 3ir5:B, 3ir6:B, 3ir7:B, 1q16:B, 1r27:B, 1r27:D, 1siw:B, 1y4z:B, 1y5i:B, 1y5l:B, 1y5n:B
13 6cz7:B 234 247 0.1903 0.2350 0.2227 4.66e-11 6cz7:D, 6cz8:D, 6cz8:B, 6cz9:B, 6cz9:D, 6cza:B, 6cza:D
14 4v4c:B 274 158 0.1349 0.1423 0.2468 3.17e-09 4v4c:D, 4v4c:F, 4v4c:H, 4v4c:J, 4v4c:L, 4v4c:N, 4v4c:P, 4v4c:R, 4v4c:T, 4v4c:V, 4v4c:X, 4v4d:B, 4v4d:D, 4v4d:F, 4v4d:H, 4v4d:J, 4v4d:L, 4v4d:N, 4v4d:P, 4v4d:R, 4v4d:T, 4v4d:V, 4v4d:X, 4v4e:B, 4v4e:D, 4v4e:F, 4v4e:H, 4v4e:J, 4v4e:L, 4v4e:N, 4v4e:P, 4v4e:R, 4v4e:T, 4v4e:V, 4v4e:X
15 6x6u:B 167 80 0.0969 0.1677 0.3500 1.30e-08 6x1o:B, 6x1o:D, 6x6u:D
16 7b04:A 409 68 0.0796 0.0562 0.3382 2.79e-06 7b04:D, 7b04:G, 7b04:J, 7b04:M, 7b04:P, 7b04:S, 7b04:V
17 7qv7:A 174 116 0.1176 0.1954 0.2931 5.01e-06 7qv7:G
18 7qv7:A 174 85 0.0830 0.1379 0.2824 2.2 7qv7:G
19 6lod:B 929 234 0.1903 0.0592 0.2350 5.02e-06 6loe:B
20 7z0s:B 170 189 0.1834 0.3118 0.2804 8.83e-06 7z0t:B
21 6btm:B 948 141 0.1211 0.0369 0.2482 1.07e-04
22 5odc:A 653 81 0.0934 0.0413 0.3333 0.001 5odc:G, 5odh:A, 5odh:G, 5odi:A, 5odi:G, 5odq:A, 5odq:G, 5odr:A, 5odr:G
23 8a8o:D 102 85 0.0934 0.2647 0.3176 0.007 8a8o:C
24 7bkb:L 79 74 0.0727 0.2658 0.2838 0.044 7bkb:l, 7bkc:L, 7bkc:l
25 7bkb:L 79 38 0.0450 0.1646 0.3421 1.8 7bkb:l, 7bkc:L, 7bkc:l
26 3mm5:B 363 53 0.0554 0.0441 0.3019 0.054 3mm5:E, 3mm6:B, 3mm6:E, 3mm7:B, 3mm7:E, 3mm8:B, 3mm8:E, 3mm9:B, 3mm9:E, 3mma:B, 3mma:E, 3mmb:B, 3mmb:E, 3mmc:B, 3mmc:E
27 6fah:E 393 93 0.1107 0.0814 0.3441 0.10 6fah:A
28 7bkb:K 386 104 0.1038 0.0777 0.2885 0.10 7bkb:k, 7bkc:M, 7bkc:m
29 7bkb:K 386 158 0.1419 0.1062 0.2595 3.9 7bkb:k, 7bkc:M, 7bkc:m
30 6cfw:N 121 69 0.0588 0.1405 0.2464 0.12
31 7koe:D 92 76 0.0727 0.2283 0.2763 0.13 7koe:H
32 5t61:L 348 187 0.1522 0.1264 0.2353 0.16 5t5i:F, 5t5i:N, 5t5m:F, 5t61:F, 5t61:R, 5t61:X, 5t61:d, 5t61:j, 5t61:p, 5t61:v
33 8atu:A 2837 30 0.0484 0.0049 0.4667 0.16 8atu:B, 8atx:A, 8atx:B, 8auk:A, 8auk:B, 8auw:B
34 8auw:A 2900 30 0.0484 0.0048 0.4667 0.16
35 8a6t:B 630 78 0.0934 0.0429 0.3462 0.17 8a6t:E, 8bew:B, 8bew:E
36 4hea:9 180 84 0.0900 0.1444 0.3095 0.22 2fug:9, 2fug:G, 2fug:P, 2fug:Y, 4hea:O, 6i0d:9, 6i0d:O, 6i1p:9, 6i1p:O, 3i9v:9, 3i9v:G, 3iam:9, 3iam:G, 3ias:9, 3ias:G, 3ias:P, 3ias:Y, 3m9s:9, 3m9s:G, 6q8o:9, 6q8o:O, 6q8w:9, 6q8w:O, 6q8x:9, 6q8x:O, 6y11:9, 6y11:O, 2ybb:8, 6ziy:9, 6zjl:9, 6zjn:9, 6zjy:9
37 4hea:9 180 99 0.0761 0.1222 0.2222 3.3 2fug:9, 2fug:G, 2fug:P, 2fug:Y, 4hea:O, 6i0d:9, 6i0d:O, 6i1p:9, 6i1p:O, 3i9v:9, 3i9v:G, 3iam:9, 3iam:G, 3ias:9, 3ias:G, 3ias:P, 3ias:Y, 3m9s:9, 3m9s:G, 6q8o:9, 6q8o:O, 6q8w:9, 6q8w:O, 6q8x:9, 6q8x:O, 6y11:9, 6y11:O, 2ybb:8, 6ziy:9, 6zjl:9, 6zjn:9, 6zjy:9
38 7q4v:B 599 55 0.0727 0.0351 0.3818 0.23 8a5e:B, 7q4v:F, 7q4w:B, 7q4w:F
39 7q4v:B 599 156 0.1246 0.0601 0.2308 2.2 8a5e:B, 7q4v:F, 7q4w:B, 7q4w:F
40 4z3w:F 170 170 0.1453 0.2471 0.2471 0.29 4z3w:E, 4z3w:G, 4z3w:H, 4z3x:E, 4z3x:F, 4z3x:G, 4z3x:H, 4z3y:E, 4z3y:F, 4z3y:G, 4z3y:H, 4z3z:E, 4z3z:F, 4z3z:G, 4z3z:H, 4z40:E, 4z40:F, 4z40:G, 4z40:H
41 5c4i:E 312 65 0.0761 0.0705 0.3385 0.48 5c4i:B, 5exd:E, 5exe:B
42 5exd:H 291 65 0.0761 0.0756 0.3385 0.49 5exd:B, 5exd:K, 5exe:E
43 3bk7:A 593 44 0.0554 0.0270 0.3636 0.50 3j15:B, 5lw7:B, 1yqt:A, 5yv5:A
44 6hum:I 193 82 0.0692 0.1036 0.2439 0.86 6khi:I, 6khj:I, 6l7o:I, 6l7p:I, 6nbq:I, 6nbx:I, 6nby:I, 6tjv:I
45 7zc6:B 202 39 0.0484 0.0693 0.3590 0.90
46 7bkd:A 664 68 0.0692 0.0301 0.2941 0.96 7bkb:A, 7bkb:a, 7bkc:A, 7bkc:a, 7bkd:a, 7bke:A, 7bke:a
47 2cs8:A 108 91 0.0865 0.2315 0.2747 1.0
48 6tmf:d 582 44 0.0554 0.0275 0.3636 1.1 3ozx:A, 3ozx:B
49 7wfg:I 160 73 0.0657 0.1187 0.2603 1.1 7wg5:I
50 7wfg:I 160 92 0.0830 0.1500 0.2609 4.9 7wg5:I
51 7bkc:K 321 86 0.0865 0.0779 0.2907 1.3 7bkc:k
52 7bkc:K 321 126 0.1211 0.1090 0.2778 4.1 7bkc:k
53 7p63:I 180 72 0.0727 0.1167 0.2917 1.3 7awt:I, 7nyr:I, 7nyu:I, 7nyv:I, 7nz1:I, 7p61:I, 7p62:I, 7p64:I, 7p69:I, 7p7c:I, 7p7e:I, 7p7j:I, 7p7k:I, 7p7l:I, 7p7m:I, 7z7r:I, 7z7s:I, 7z7t:I, 7z7v:I, 7z80:I, 7z83:I, 7z84:I, 7zc5:I, 7zci:I
54 7o80:Bz 595 33 0.0554 0.0269 0.4848 1.8 7a09:J, 6hcf:k1, 6hcm:k1, 3jag:jj, 3jah:jj, 3jai:jj, 5lzv:jj, 8p03:k, 8p09:k, 8scb:jj, 6yal:k, 6yam:k, 6zme:CI, 6zvj:1
55 8e9i:I 166 88 0.0830 0.1446 0.2727 2.6 8e9g:I, 8e9h:I
56 8e9i:I 166 77 0.0761 0.1325 0.2857 3.9 8e9g:I, 8e9h:I
57 7p8n:B 613 55 0.0588 0.0277 0.3091 2.6 7p5h:B, 7p5h:E, 7p5h:b, 7p5h:e, 7p8n:b, 7p91:b, 7p91:B, 7p92:B
58 4crm:P 608 14 0.0311 0.0148 0.6429 3.5 7a1g:x, 8cah:x, 3j16:B
59 6tg9:A 949 18 0.0311 0.0095 0.5000 3.7 6tg9:E, 6tga:A, 6tga:E
60 6tg9:A 949 58 0.0554 0.0169 0.2759 5.5 6tg9:E, 6tga:A, 6tga:E
61 8cas:k 579 14 0.0311 0.0155 0.6429 3.8 5ll6:h, 6zce:k, 6zu9:k
62 1h98:A 77 49 0.0519 0.1948 0.3061 4.0
63 6u8y:N 176 70 0.0727 0.1193 0.3000 4.5 6u8y:n
64 3eun:A 81 68 0.0692 0.2469 0.2941 4.7 1blu:A, 3exy:A
65 2fgo:A 81 70 0.0692 0.2469 0.2857 5.0
66 3lq3:A 339 76 0.0865 0.0737 0.3289 5.4 3feg:A
67 7q5y:D 197 57 0.0657 0.0964 0.3333 5.9 7q5y:J, 7q5y:P, 7q5y:V
68 7zc6:C 435 19 0.0311 0.0207 0.4737 5.9
69 3or1:B 385 48 0.0588 0.0442 0.3542 6.0 3or1:E, 3or2:B, 3or2:E
70 3zxs:A 508 101 0.0969 0.0551 0.2772 6.6 3zxs:B, 3zxs:C
71 1hfe:L 396 52 0.0554 0.0404 0.3077 6.7 8bj7:A, 8bj8:A, 1e08:A, 1gx7:A, 1hfe:M, 6sg2:AAA
72 7z0s:F 164 51 0.0588 0.1037 0.3333 7.0 7z0t:F
73 7vzg:B 76 74 0.0727 0.2763 0.2838 7.1
74 2vkr:A 103 71 0.0727 0.2039 0.2958 9.6 2vkr:B, 2vkr:C, 2vkr:D, 2vkr:E, 2vkr:F, 2vkr:G, 1xer:A
75 6oeo:B 346 33 0.0415 0.0347 0.3636 9.6 6cg0:B, 6cg0:D, 6cij:B, 6cij:D, 6cik:B, 6cil:B, 6oeo:D, 6oeq:D, 6oer:D, 6oes:B, 6oes:D, 6oet:D, 6oet:B, 6xnx:B, 6xnx:D, 6xny:B, 6xny:D, 6xnz:B, 6xnz:D, 5zdz:B, 5zdz:D, 5ze0:B, 5ze0:D, 5ze1:B, 5ze1:D, 5ze2:B, 5ze2:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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