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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ALRYPMAVGLNKGHKVTKNVSKPRHSRRRGRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHI
RAKRKREELSSVLAAMRKAAAK

The query sequence (length=102) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7qgg:j 104 102 0.9902 0.9712 0.9902 5.66e-69 7a01:B2, 8a3d:c, 5aj0:Ai, 8b5l:i, 8b6c:i, 9bdl:AL36, 9bdn:AL36, 9bdp:AL36, 7bhp:Li, 8bhf:V1, 8bpo:h2, 8btk:Bi, 7cpu:Li, 7cpv:Li, 4d5y:i, 4d67:i, 6d90:i, 6d9j:i, 9f1b:Bi, 9f1c:Bi, 9f1d:Bi, 7f5s:Li, 8fkp:LU, 8fkq:LU, 8fkr:LU, 8fks:LU, 8fkt:LU, 8fku:LU, 8fkv:LU, 8fkw:LU, 8fkx:LU, 8fky:LU, 8fkz:LU, 8fl2:LU, 8fl3:LU, 8fl4:LU, 8fl6:LU, 8fl7:LU, 8fl9:LU, 8fla:LU, 8flb:LU, 8flc:LU, 8fld:LU, 8fle:LU, 8flf:LU, 6frk:i, 6ftg:i, 6fti:i, 6ftj:i, 8g5y:Li, 8g5z:Li, 8g60:Li, 8g61:Li, 8g6j:Li, 8glp:Li, 6gz3:Ai, 6gz4:Ai, 6gz5:Ai, 6hcf:i3, 6hcj:i3, 6hcm:i3, 6hcq:i3, 8idt:K, 8idy:K, 8ie3:K, 8ifd:2c, 8ife:2c, 8ine:K, 8inf:K, 8ink:K, 6ip5:2c, 6ip6:2c, 6ip8:2c, 8ipd:K, 8ipx:K, 8ipy:K, 8ir1:K, 8ir3:K, 3j7o:i, 3j7p:i, 3j7q:i, 3j7r:i, 3j92:i, 3jag:i, 3jah:i, 3jai:i, 3jaj:i, 3jan:i, 8jdj:n, 8jdk:n, 8jdl:n, 8jdm:n, 8k2c:Li, 5lks:Li, 6lqm:K, 6lsr:K, 6lss:K, 7ls1:c2, 7ls2:c2, 6lu8:K, 5lzs:i, 5lzt:i, 5lzu:i, 5lzv:i, 5lzw:i, 5lzx:i, 5lzy:i, 5lzz:i, 7mdz:i, 6mtb:i, 6mtc:i, 6mtd:i, 6mte:i, 7nfx:i, 7nwg:i3, 7nwh:i, 7nwi:i, 7o7y:Bi, 7o7z:Bi, 7o80:Bi, 7o81:Bi, 7obr:i, 8ohd:Li, 8oj0:Li, 8oj5:Li, 8oj8:Li, 6ole:j, 6olf:j, 6olg:Ai, 6oli:j, 6olz:Ai, 6om0:j, 6om7:j, 7ow7:c, 7oya:i1, 7oyb:i1, 7oyc:i1, 7oyd:i, 8p2k:Bi, 6p5i:Ai, 6p5j:Ai, 6p5k:Ai, 6p5n:Ai, 8q7z:Bi, 8q87:Bi, 8qfd:i, 8qoi:Li, 7qvp:Li, 7qvp:Mi, 7qwq:i, 7qwr:i, 7qws:i, 6qzp:Li, 6r5q:i, 6r6g:i, 6r6p:i, 6r7q:i, 8rjb:i, 8rjc:i, 8rjd:i, 8scb:i, 6sgc:i2, 6swa:g, 5t2c:c, 6t59:i3, 7tm3:i, 7toq:AL36, 7tor:AL36, 7tut:i, 7ucj:i, 7uck:i, 4ug0:Li, 4ujc:Bi, 4ujd:Ai, 4uje:Ci, 4v6x:Ci, 6w6l:j, 6xa1:Li, 7xnx:Li, 7xny:Li, 8xsx:Li, 8xsy:Li, 8xsz:Li, 6y0g:Li, 8y0w:Li, 8y0x:Li, 6y2l:Li, 6y57:Li, 6y6x:Li, 8yoo:Li, 8yop:Li, 6z6l:Li, 6z6m:Li, 6z6n:Li, 7zjw:Ll, 7zjx:Ll, 6zm7:Li, 6zme:Li, 6zmi:Li, 6zmo:Li, 6zvk:B2
2 4v6w:Ci 113 111 0.6569 0.5929 0.6036 5.02e-41 6xu6:Ci, 6xu7:Ci, 6xu8:Ci
3 9bh5:Ci 104 94 0.5588 0.5481 0.6064 4.19e-36 9cai:Ci
4 8ip8:AB 100 94 0.5882 0.6000 0.6383 7.82e-35 8ipa:AB, 8ipb:AB, 8jiv:Ci
5 7qiw:k 100 92 0.5784 0.5900 0.6413 8.92e-35 8azw:U, 8b2l:U3, 7qiz:k
6 7r81:k1 96 93 0.5490 0.5833 0.6022 2.71e-31
7 7olc:Li 102 91 0.5490 0.5490 0.6154 4.83e-31 8i9p:Li, 8i9r:Li, 8i9t:Li, 8i9v:Li, 8i9w:Li, 8i9x:Li, 8i9y:Li, 8i9z:Li, 8ia0:Li, 7old:Li, 8oo0:Li, 8pv1:Li, 8pv2:Li, 8pv3:Li, 8pv4:Li, 8pv5:Li, 8pv6:Li, 8pv7:Li, 8pv8:Li, 8pvk:Li, 8pvl:Li, 7z3n:Li, 7z3o:Li
8 8eth:i 98 94 0.5392 0.5612 0.5851 1.10e-29 8esq:i, 8esr:i, 8etc:i, 8etg:i, 8eti:i, 8etj:i, 8eug:i, 8eui:i, 8eup:i, 8euy:i, 8ev3:i
9 4v3p:Lk 77 69 0.4510 0.5974 0.6667 5.44e-26 4v7e:Ci
10 5xxb:h 97 96 0.5000 0.5258 0.5312 7.84e-26
11 8aaf:V 99 93 0.4314 0.4444 0.4731 8.85e-26 8agt:V, 8agu:V, 8agv:V, 8agw:V, 8agx:V, 8agz:V, 5apn:i, 5apo:i, 7azy:d, 7b7d:Le, 8bip:Li, 8bjq:Li, 8bn3:O6, 8bqd:AC, 8bqx:AC, 7bt6:i, 7btb:i, 6c0f:i, 6cb1:i, 8ccs:U, 8cdl:U, 8cdr:U, 8ceh:U, 8cf5:U, 8cg8:U, 8cgn:U, 8civ:U, 8cku:U, 8cmj:U, 5dat:O6, 5dat:o6, 5dc3:O6, 5dc3:o6, 5dge:O6, 5dge:o6, 5dgf:O6, 5dgf:o6, 5dgv:O6, 5dgv:o6, 8e5t:i, 6elz:i, 6em1:i, 6em3:i, 6em4:i, 6em5:i, 8eub:Ai, 8evp:Ai, 8evq:Ai, 8evr:Ai, 8evs:Ai, 8evt:Ai, 8ewb:Ai, 8ewc:Ai, 5fci:O6, 5fci:o6, 5fcj:O6, 5fcj:o6, 6ft6:i, 5gak:k, 6gq1:i, 6gqb:i, 6gqv:i, 5h4p:i, 6hd7:k, 8hfr:ia, 6hhq:AJ, 6hhq:DK, 5i4l:O6, 5i4l:o6, 6i7o:AC, 6i7o:XC, 3j6x:76, 3j6y:76, 3j77:86, 3j78:86, 3jct:i, 5jcs:i, 5juo:NA, 5jup:NA, 5jus:NA, 5jut:NA, 5juu:NA, 8k2d:Li, 8k82:Li, 5lyb:O6, 5lyb:o6, 5m1j:i5, 6m62:i, 5mc6:AC, 5mei:AJ, 5mei:DK, 7mpi:Ai, 7mpj:Ai, 6n8j:i, 6n8k:i, 6n8l:i, 6n8m:v, 6n8n:v, 6n8o:v, 7n8b:Ai, 7nac:i, 5ndg:O6, 5ndg:o6, 5ndv:O6, 5ndv:o6, 5ndw:O6, 5ndw:o6, 7nrc:Lk, 7nrd:Lk, 5obm:O6, 5obm:o6, 7of1:i, 7oh3:i, 7ohp:i, 7ohq:i, 7ohr:i, 7ohs:i, 7ohu:i, 7ohv:i, 7ohw:i, 6oig:i, 5on6:AJ, 5on6:DK, 7osa:eL36, 7osm:eL36, 8p8m:RI, 8p8n:RI, 8p8u:RI, 8pfr:RI, 6q8y:AC, 6qik:h, 6qt0:h, 6qtz:h, 7r6k:i, 7r7a:i, 6r84:k, 6r86:k, 6r87:k, 6ri5:h, 7rr5:Li, 6rzz:h, 6s05:h, 6s47:Ak, 6snt:ah, 6sv4:AC, 6sv4:XC, 6sv4:zC, 6t4q:Li, 5t62:v, 5t6r:v, 6t7i:Li, 6t7t:Li, 6t83:ib, 6t83:T, 5tbw:AJ, 5tbw:DK, 6tb3:AC, 5tga:O6, 5tga:o6, 5tgm:O6, 5tgm:o6, 6tnu:AC, 7too:AL36, 7top:AL36, 7u0h:i, 4u3m:O6, 4u3m:o6, 4u3n:O6, 4u3n:o6, 4u3u:O6, 4u3u:o6, 4u4n:O6, 4u4n:o6, 4u4o:O6, 4u4o:o6, 4u4q:O6, 4u4q:o6, 4u4r:O6, 4u4r:o6, 4u4u:O6, 4u4u:o6, 4u4y:O6, 4u4y:o6, 4u4z:O6, 4u4z:o6, 4u50:O6, 4u50:o6, 4u51:O6, 4u51:o6, 4u52:O6, 4u52:o6, 4u53:O6, 4u53:o6, 4u55:O6, 4u55:o6, 4u56:O6, 4u56:o6, 4u6f:O6, 4u6f:o6, 7ug6:i, 7uoo:i, 7uqb:i, 7uqz:i, 7v08:i, 4v6i:Bk, 4v7f:g, 4v88:Bi, 4v88:Di, 4v8t:i, 4v8y:Bi, 4v8z:Bi, 8v83:i, 8v84:i, 8v87:i, 4v91:i, 6woo:i, 6xiq:i, 6xir:i, 8y0u:Li, 6ylg:i, 6ylh:i, 6ylx:i, 6yly:i, 5z3g:m, 7z34:i, 6z6j:Li, 6z6k:Li, 7zpq:Bh, 7zrs:Bh, 7zs5:Bj, 7zuw:Bh, 7zux:Eh, 7zw0:Ll
12 5it7:ii 98 93 0.4314 0.4490 0.4731 1.35e-23 6uz7:Bi
13 6zj3:Lx 102 81 0.4216 0.4216 0.5309 1.22e-20
14 3j79:b 95 96 0.4020 0.4316 0.4271 2.92e-20 3jbn:Ab, 3jbo:Ab, 3jbp:Ab, 8tpu:Ab, 5umd:b
15 7pzy:AJ 98 93 0.4412 0.4592 0.4839 9.08e-19 8c3a:AJ, 8c3a:CD, 8cq7:AJ, 8cq7:CD, 8cqw:AJ, 8cqw:CD, 8cre:AJ, 8cre:CD, 8oeq:AJ, 8oeq:CD, 7q08:AJ, 7q0f:AJ, 7q0p:AJ, 7q0r:AJ, 8q5i:AJ
16 4v8p:AQ 102 99 0.4608 0.4608 0.4747 1.49e-18 4v8p:DQ, 4v8p:FQ, 4v8p:HQ
17 4v8m:Bm 106 91 0.3725 0.3585 0.4176 4.26e-17 8ova:Bm, 8ove:Bm, 5t5h:m
18 8rxh:Li 102 88 0.3333 0.3333 0.3864 1.92e-15 8a98:i, 6az3:i, 3jcs:i, 8rxx:Li, 5t2a:k
19 8a3w:i 86 91 0.3431 0.4070 0.3846 1.15e-13 8ovj:i
20 8br8:Lj 89 56 0.2745 0.3146 0.5000 1.87e-13 8brm:Lj, 8bsi:Lj, 8bsj:Lj, 8btd:Lj, 8btr:Lj, 8fru:i, 7pwg:i, 7pwo:i2
21 6zu5:LII 97 70 0.2353 0.2474 0.3429 4.30e-12
22 6rm3:LII 93 80 0.2941 0.3226 0.3750 1.08e-11
23 5xy3:i 73 60 0.2451 0.3425 0.4167 1.91e-11
24 8p5d:LII 97 91 0.3627 0.3814 0.4066 6.98e-11 8p60:LII, 8p60:KII, 7qca:LII
25 7r6q:i 58 73 0.2451 0.4310 0.3425 2.02e-09
26 7qep:O6 94 62 0.2059 0.2234 0.3387 8.42e-07
27 7xyf:K 656 67 0.1667 0.0259 0.2537 0.52 7xyg:K
28 1aor:A 605 45 0.1569 0.0264 0.3556 1.6 1aor:B
29 5b7i:A 1044 43 0.1569 0.0153 0.3721 3.3
30 8cmo:6 226 51 0.1765 0.0796 0.3529 4.0
31 2pd3:A 274 60 0.1863 0.0693 0.3167 4.5 8jfm:A, 8jfm:B, 8jfm:C, 8jfm:D, 8jfm:E, 8jfm:F, 8jfm:G, 8jfm:H, 8jfn:A, 2pd3:B, 2pd3:C, 2pd3:D, 2pd4:A, 2pd4:B, 2pd4:C, 2pd4:D
32 4b3g:A 614 33 0.1176 0.0195 0.3636 8.5 4b3g:B
33 6rop:B 831 30 0.1275 0.0156 0.4333 8.9
34 5my0:A 852 30 0.1275 0.0153 0.4333 8.9 5my0:C, 5my0:D, 5my2:D, 6rop:A, 6rop:C, 6rop:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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