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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ALRIPRFSQGIAQDPTTRRIWFGIATAHDFESHDDITEGRLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFEAWVQDP
FHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNNAYSGVYQWWYTIGLRTNEDLYTGAIFLLFLSFISLLAGWLHLQPKW
KPSVSWFKNAESRLNHHLSGLFGVSSLAWAGHLVHVAIPGSRGEYVRWNNFLDVLPYPQGLGPLLTGQWNLYAQNPSSSN
HLFGTTQGAGTAILTILGGFHPQTQSLWLTDVAHHHLAIAFLFLIGGLMYRTNFGIGHSIKYILEAHIPPGGRLGRGHKG
LYDTINNSIHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGPIFFIRDYNPE
QNADNVLARMLEHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTTYGFDIPLSST
NGPALNAGRNIWLPGWLNAINENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDG
PGRGGTCDISAWDDFYLAVFWMLNTIGWVTFYWHWKHITLWRGNVSQFNESSTYLMGWLRDYLWLNSSQLINGITPLVCN
SLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLVHFSVGYIFTY
AAFLIASTSGKFG

The query sequence (length=733) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7wfd:AB 734 733 0.9372 0.9360 0.9372 0.0 8bcv:B, 8bcw:B, 7dkz:B, 7ew6:B, 7ewk:B, 7f9o:B, 7f9o:f, 8htu:B, 8j6z:B, 8j7a:B, 8j7b:B, 7ksq:B, 7kux:B, 6l35:B, 5l8r:B, 3lw5:B, 2o01:B, 4rku:B, 7wfe:BB, 7wg5:AB, 7wg5:BB, 8wgh:B, 2wsc:B, 2wse:B, 2wsf:B, 4xk8:B, 4xk8:b, 7xqp:B, 4y28:B, 6yac:B, 6yez:B, 5zji:B, 6zoo:B, 6zxs:B
2 6igz:B 733 733 0.8213 0.8213 0.8213 0.0
3 7d0j:B 734 729 0.8158 0.8147 0.8203 0.0 7a4p:B, 7bgi:B, 7blx:B, 8cmo:B, 7dz7:B, 7dz8:B, 8h2u:B, 6ijj:B, 6ijo:B, 6jo5:B, 6jo6:B, 6qph:B, 7r3k:B, 6rhz:B, 6sl5:B, 7wyi:B, 7wzn:B, 6yxr:B, 7zq9:B, 7zqc:B, 7zqd:B, 7zqd:B2, 6zzx:B, 6zzy:B
4 7y5e:BN 732 731 0.8022 0.8033 0.8044 0.0 7y5e:B2, 7y7a:B7, 7y7a:Bo, 7y7b:B, 7y8a:B
5 7yca:B 732 733 0.8063 0.8074 0.8063 0.0
6 8wm6:B 732 731 0.7763 0.7773 0.7784 0.0 8wmj:B, 8wmv:B, 8wmw:B
7 6vpv:B 737 738 0.7926 0.7883 0.7873 0.0 8am5:b, 8asl:b, 8asp:b, 6hqb:B, 4kt0:B, 4l6v:B, 4l6v:b, 4l6v:2, 6nwa:B, 6nwa:b, 6nwa:G, 7o1v:B, 5oy0:B, 5oy0:b, 5oy0:2, 7umh:B, 7umh:G, 7umh:b, 6uzv:B, 6uzv:b, 6uzv:2, 6vpv:b, 6vpv:2
8 7blz:B 731 732 0.7817 0.7839 0.7828 0.0 6fos:B, 8wey:B, 5zgb:B, 5zgh:B
9 6kif:B 733 733 0.7804 0.7804 0.7804 0.0 6kif:H, 6kif:f, 6kig:B, 6kig:H, 6kig:f
10 6kmw:aB 740 740 0.7790 0.7716 0.7716 0.0 6kmw:cB, 6kmw:bB
11 7fix:B1 740 740 0.7844 0.7770 0.7770 0.0 7bw2:B, 4fe1:B, 7fix:B2, 7fix:B3, 1jb0:B, 6k33:aB, 6k33:bB, 6k33:cB, 7m75:B, 7m76:B, 7m78:B, 3pcq:B, 6pfy:H, 6pfy:B, 6pfy:Z, 6pgk:H, 6pgk:B, 6pgk:Z, 6tra:B, 6trc:B, 6trc:b, 6trc:2, 6trd:B, 6trd:b, 6trd:2, 5zf0:B1, 5zf0:B2, 5zf0:B3, 5zf0:B4, 5zf0:B6, 5zf0:B5
12 6ly5:b 732 733 0.7653 0.7664 0.7653 0.0 6l4u:B
13 7qco:B 734 734 0.7585 0.7575 0.7575 0.0 7qco:G, 7qco:g, 7qco:b
14 6k61:B 740 740 0.7599 0.7527 0.7527 0.0 6jeo:aB, 6jeo:bB, 6jeo:cB, 6jeo:dB, 6k61:b, 6tcl:B1, 6tcl:B2, 6tcl:B, 6tcl:BB, 7y3f:B
15 6lu1:B 713 735 0.7681 0.7896 0.7660 0.0
16 7dr0:B 706 733 0.7572 0.7861 0.7572 0.0 7dr1:B, 7dr2:aB, 7dr2:bB, 7dr2:cB, 7dr2:dB
17 7s3d:B 742 742 0.7381 0.7291 0.7291 0.0 7s3d:H, 7s3d:b
18 6kmx:aB 727 735 0.7312 0.7373 0.7293 0.0 6kmx:bB, 6kmx:cB
19 7lx0:H 739 740 0.7326 0.7267 0.7257 0.0 7lx0:b, 7lx0:B, 6pnj:H, 6pnj:B, 6pnj:b
20 7f4v:aB 725 731 0.7217 0.7297 0.7237 0.0 7f4v:bB, 7f4v:cB
21 7dwq:B 659 727 0.6521 0.7253 0.6575 0.0 7coy:aB, 7coy:bB, 7coy:cB
22 5l8r:A 743 754 0.4516 0.4455 0.4390 0.0 8bcv:A, 8bcw:A, 7dkz:A, 7ew6:A, 7ewk:A, 7f9o:A, 7f9o:e, 8htu:A, 8j6z:A, 8j7a:A, 8j7b:A, 7ksq:A, 7kux:A, 6l35:A, 3lw5:A, 2o01:A, 4rku:A, 7wfd:AA, 7wfe:BA, 7wg5:AA, 7wg5:BA, 8wgh:A, 2wsc:A, 2wse:A, 2wsf:A, 4xk8:A, 4xk8:a, 7xqp:A, 4y28:A, 6yac:A, 6yez:A, 5zji:A, 6zoo:A, 6zxs:A
23 7y5e:AN 745 753 0.4407 0.4336 0.4290 0.0 7y5e:A2, 7y7a:A7, 7y7a:Ao
24 7f4v:aA 772 764 0.4475 0.4249 0.4293 0.0 7f4v:bA, 7f4v:cA
25 6k61:A 742 757 0.4434 0.4380 0.4293 0.0 6jeo:aA, 6jeo:bA, 6jeo:cA, 6jeo:dA, 6k61:a, 6tcl:A1, 6tcl:A2, 6tcl:A, 6tcl:AA, 7y3f:A
26 6tra:A 746 749 0.4434 0.4357 0.4339 0.0 4fe1:A, 7fix:A1, 7fix:A2, 7fix:A3, 1jb0:A, 6k33:aA, 6k33:bA, 6k33:cA, 6lu1:A, 7m75:A, 7m76:A, 7m78:A, 3pcq:A, 6pfy:A, 6pfy:G, 6pfy:Y, 6pgk:A, 6pgk:G, 6pgk:Y, 6trc:A, 6trc:a, 6trc:1, 6trd:A, 6trd:a, 6trd:1, 5zf0:A1, 5zf0:A2, 5zf0:A3, 5zf0:A4, 5zf0:A6, 5zf0:A5
27 7blz:A 743 753 0.4420 0.4361 0.4303 0.0 6fos:A, 8wey:A, 5zgb:A, 5zgh:A
28 8wm6:A 742 748 0.4461 0.4407 0.4372 0.0 8wmj:A, 8wmv:A, 8wmw:A, 7y7b:A, 7y8a:A
29 6kif:A 751 765 0.4434 0.4328 0.4248 0.0 6kif:G, 6kif:e, 6kig:A, 6kig:G, 6kig:e
30 7yca:A 742 752 0.4352 0.4299 0.4242 0.0 7a4p:A, 7bgi:A, 7blx:A, 8cmo:A, 7d0j:A, 7dz7:A, 7dz8:A, 8h2u:A, 6ijj:A, 6ijo:A, 6jo5:A, 6jo6:A, 7r3k:A, 7wyi:A, 7wzn:A, 7zq9:A, 7zqc:A, 7zqd:A, 7zqd:A2, 6zzx:A, 6zzy:A
31 5oy0:A 751 745 0.4393 0.4288 0.4322 0.0 8am5:a, 8asl:a, 8asp:a, 6hqb:A, 4kt0:A, 4l6v:A, 4l6v:a, 4l6v:1, 6nwa:A, 6nwa:a, 6nwa:H, 7o1v:A, 5oy0:a, 5oy0:1, 7umh:A, 7umh:H, 7umh:a, 6uzv:A, 6uzv:a, 6uzv:1, 6vpv:A, 6vpv:a, 6vpv:1
32 7dr0:A 739 754 0.4297 0.4263 0.4178 0.0 7dr1:A, 7dr2:aA, 7dr2:bA, 7dr2:cA, 7dr2:dA
33 6igz:A 740 745 0.4352 0.4311 0.4282 0.0 6qph:A, 6rhz:A, 6sl5:A, 6yxr:A
34 6ly5:a 742 755 0.4297 0.4245 0.4172 2.98e-180 6l4u:A
35 7qco:A 728 753 0.4338 0.4368 0.4223 9.32e-180 7qco:E, 7qco:e, 7qco:a
36 6kmw:aA 721 756 0.4352 0.4424 0.4220 1.70e-179 6kmw:bA, 6kmw:cA
37 7dwq:A 726 753 0.4134 0.4174 0.4024 6.46e-179
38 7s3d:A 749 763 0.4311 0.4219 0.4142 2.90e-178 7s3d:G, 7s3d:a
39 7coy:aA 685 727 0.4052 0.4336 0.4085 1.27e-174 7coy:bA, 7coy:cA
40 7lx0:G 751 752 0.4297 0.4194 0.4189 1.58e-171 7lx0:a, 7lx0:A, 6pnj:A, 6pnj:G, 6pnj:a
41 8jze:b 663 735 0.4175 0.4615 0.4163 2.28e-170 8jzf:b
42 8jw0:b 617 721 0.4120 0.4895 0.4189 7.68e-170
43 8jjr:b 659 740 0.4311 0.4795 0.4270 5.23e-169
44 6kmx:aA 717 737 0.4079 0.4170 0.4057 1.42e-166 6kmx:bA, 6kmx:cA
45 8jjr:a 665 732 0.3192 0.3519 0.3197 2.35e-102
46 8jze:a 670 737 0.3042 0.3328 0.3026 2.08e-93 8jzf:a
47 8jw0:a 645 732 0.3165 0.3597 0.3169 1.29e-92
48 7zq9:B2 180 215 0.1746 0.7111 0.5953 3.54e-73
49 7zq9:B2 180 27 0.0191 0.0778 0.5185 0.11
50 5v8k:A 600 365 0.1269 0.1550 0.2548 1.95e-12
51 6m32:A 628 80 0.0396 0.0462 0.3625 1.37e-05 6m32:a
52 8gwa:A 667 80 0.0396 0.0435 0.3625 1.60e-05 8gwa:a, 7uea:A, 7uea:a, 7ueb:A, 7ueb:a, 7z6q:A, 7z6q:a
53 7vzg:a 858 116 0.0409 0.0350 0.2586 5.46e-04 7vzg:A, 7vzr:A, 7vzr:a
54 4gfv:B 288 61 0.0314 0.0799 0.3770 0.043 4gfu:A, 4gfv:A, 4nnd:A, 4nnd:B, 4nnd:D, 4nnd:G

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218