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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEGRLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFEAWVQDP
LHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYTGAIFLLFLSFISLLAGWLHLQPKW
KPSVSWFKNAESRLNHHLSGLFGVSSLAWAGHLVHVAIPGSRGEYVRWNNFLSVLPHPQGLGPLFTGQWNLYAQNPDSSN
HLFSTSQGAGTAILTLLGGFHPQTQSLWLTDMAHHHLAIAILFLIGGHMYRTNFGIGHSIKYILEAHIPPGGRLGRGHKG
LYDTINNSIHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPE
QNADNVLARMLEHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSST
NSPALNAGRSIWLPGWLNAINENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDG
PGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMN
SLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLVHFSVGYIFTY
AAFLIASTSGKFG

The query sequence (length=733) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7wfd:AB 734 733 0.9673 0.9659 0.9673 0.0 8bcv:B, 8bcw:B, 7dkz:B, 7ew6:B, 7ewk:B, 7f9o:B, 7f9o:f, 8htu:B, 8j6z:B, 8j7a:B, 8j7b:B, 7ksq:B, 7kux:B, 6l35:B, 5l8r:B, 3lw5:B, 2o01:B, 4rku:B, 7wfe:BB, 7wg5:AB, 7wg5:BB, 8wgh:B, 2wsc:B, 2wse:B, 2wsf:B, 4xk8:B, 4xk8:b, 7xqp:B, 4y28:B, 6yac:B, 6yez:B, 5zji:B, 6zoo:B, 6zxs:B
2 6igz:B 733 733 0.8486 0.8486 0.8486 0.0
3 7d0j:B 734 730 0.8417 0.8406 0.8452 0.0 7a4p:B, 7bgi:B, 7blx:B, 8cmo:B, 7dz7:B, 7dz8:B, 8h2u:B, 6ijj:B, 6ijo:B, 6jo5:B, 6jo6:B, 6qph:B, 7r3k:B, 6rhz:B, 6sl5:B, 7wyi:B, 7wzn:B, 6yxr:B, 7zq9:B, 7zqc:B, 7zqd:B, 7zqd:B2, 6zzx:B, 6zzy:B
4 7y5e:BN 732 731 0.8267 0.8279 0.8290 0.0 7y5e:B2, 7y7a:B7, 7y7a:Bo, 7y7b:B, 7y8a:B
5 7yca:B 732 733 0.8308 0.8320 0.8308 0.0
6 8wm6:B 732 731 0.8008 0.8019 0.8030 0.0 8wmj:B, 8wmv:B, 8wmw:B
7 6vpv:B 737 738 0.8131 0.8087 0.8076 0.0 8am5:b, 8asl:b, 8asp:b, 6hqb:B, 4kt0:B, 4l6v:B, 4l6v:b, 4l6v:2, 6nwa:B, 6nwa:b, 6nwa:G, 7o1v:B, 5oy0:B, 5oy0:b, 5oy0:2, 7umh:B, 7umh:G, 7umh:b, 6uzv:B, 6uzv:b, 6uzv:2, 6vpv:b, 6vpv:2
8 7blz:B 731 732 0.8076 0.8098 0.8087 0.0 6fos:B, 8wey:B, 5zgb:B, 5zgh:B
9 6kif:B 733 733 0.8035 0.8035 0.8035 0.0 6kif:H, 6kif:f, 6kig:B, 6kig:H, 6kig:f
10 6kmw:aB 740 740 0.8022 0.7946 0.7946 0.0 6kmw:cB, 6kmw:bB
11 6ly5:b 732 733 0.7899 0.7910 0.7899 0.0 6l4u:B
12 7fix:B1 740 740 0.8035 0.7959 0.7959 0.0 7bw2:B, 4fe1:B, 7fix:B2, 7fix:B3, 1jb0:B, 6k33:aB, 6k33:bB, 6k33:cB, 7m75:B, 7m76:B, 7m78:B, 3pcq:B, 6pfy:H, 6pfy:B, 6pfy:Z, 6pgk:H, 6pgk:B, 6pgk:Z, 6tra:B, 6trc:B, 6trc:b, 6trc:2, 6trd:B, 6trd:b, 6trd:2, 5zf0:B1, 5zf0:B2, 5zf0:B3, 5zf0:B4, 5zf0:B6, 5zf0:B5
13 7qco:B 734 734 0.7817 0.7807 0.7807 0.0 7qco:G, 7qco:g, 7qco:b
14 6k61:B 740 740 0.7844 0.7770 0.7770 0.0 6jeo:aB, 6jeo:bB, 6jeo:cB, 6jeo:dB, 6k61:b, 6tcl:B1, 6tcl:B2, 6tcl:B, 6tcl:BB, 7y3f:B
15 7dr0:B 706 733 0.7831 0.8130 0.7831 0.0 7dr1:B, 7dr2:aB, 7dr2:bB, 7dr2:cB, 7dr2:dB
16 6lu1:B 713 735 0.7885 0.8107 0.7864 0.0
17 7lx0:H 739 740 0.7572 0.7510 0.7500 0.0 7lx0:b, 7lx0:B, 6pnj:H, 6pnj:B, 6pnj:b
18 7s3d:B 742 742 0.7572 0.7480 0.7480 0.0 7s3d:H, 7s3d:b
19 6kmx:aB 727 735 0.7503 0.7565 0.7483 0.0 6kmx:bB, 6kmx:cB
20 7f4v:aB 725 731 0.7312 0.7393 0.7332 0.0 7f4v:bB, 7f4v:cB
21 7dwq:B 659 727 0.6658 0.7405 0.6713 0.0 7coy:aB, 7coy:bB, 7coy:cB
22 5l8r:A 743 738 0.4625 0.4563 0.4593 0.0 8bcv:A, 8bcw:A, 7dkz:A, 7ew6:A, 7ewk:A, 7f9o:A, 7f9o:e, 8htu:A, 8j6z:A, 8j7a:A, 8j7b:A, 7ksq:A, 7kux:A, 6l35:A, 3lw5:A, 2o01:A, 4rku:A, 7wfd:AA, 7wfe:BA, 7wg5:AA, 7wg5:BA, 8wgh:A, 2wsc:A, 2wse:A, 2wsf:A, 4xk8:A, 4xk8:a, 7xqp:A, 4y28:A, 6yac:A, 6yez:A, 5zji:A, 6zoo:A, 6zxs:A
23 7y5e:AN 745 753 0.4529 0.4456 0.4409 0.0 7y5e:A2, 7y7a:A7, 7y7a:Ao
24 7f4v:aA 772 768 0.4516 0.4288 0.4310 0.0 7f4v:bA, 7f4v:cA
25 6k61:A 742 753 0.4516 0.4461 0.4396 0.0 6jeo:aA, 6jeo:bA, 6jeo:cA, 6jeo:dA, 6k61:a, 6tcl:A1, 6tcl:A2, 6tcl:A, 6tcl:AA, 7y3f:A
26 6tra:A 746 741 0.4488 0.4410 0.4440 0.0 4fe1:A, 7fix:A1, 7fix:A2, 7fix:A3, 1jb0:A, 6k33:aA, 6k33:bA, 6k33:cA, 6lu1:A, 7m75:A, 7m76:A, 7m78:A, 3pcq:A, 6pfy:A, 6pfy:G, 6pfy:Y, 6pgk:A, 6pgk:G, 6pgk:Y, 6trc:A, 6trc:a, 6trc:1, 6trd:A, 6trd:a, 6trd:1, 5zf0:A1, 5zf0:A2, 5zf0:A3, 5zf0:A4, 5zf0:A6, 5zf0:A5
27 7yca:A 742 752 0.4461 0.4407 0.4348 0.0 7a4p:A, 7bgi:A, 7blx:A, 8cmo:A, 7d0j:A, 7dz7:A, 7dz8:A, 8h2u:A, 6ijj:A, 6ijo:A, 6jo5:A, 6jo6:A, 7r3k:A, 7wyi:A, 7wzn:A, 7zq9:A, 7zqc:A, 7zqd:A, 7zqd:A2, 6zzx:A, 6zzy:A
28 7blz:A 743 753 0.4516 0.4455 0.4396 0.0 6fos:A, 8wey:A, 5zgb:A, 5zgh:A
29 6kif:A 751 750 0.4516 0.4407 0.4413 0.0 6kif:G, 6kif:e, 6kig:A, 6kig:G, 6kig:e
30 5oy0:A 751 739 0.4475 0.4368 0.4438 0.0 8am5:a, 8asl:a, 8asp:a, 6hqb:A, 4kt0:A, 4l6v:A, 4l6v:a, 4l6v:1, 6nwa:A, 6nwa:a, 6nwa:H, 7o1v:A, 5oy0:a, 5oy0:1, 7umh:A, 7umh:H, 7umh:a, 6uzv:A, 6uzv:a, 6uzv:1, 6vpv:A, 6vpv:a, 6vpv:1
31 8wm6:A 742 753 0.4420 0.4367 0.4303 0.0 8wmj:A, 8wmv:A, 8wmw:A, 7y7b:A, 7y8a:A
32 7dr0:A 739 754 0.4379 0.4344 0.4257 0.0 7dr1:A, 7dr2:aA, 7dr2:bA, 7dr2:cA, 7dr2:dA
33 6igz:A 740 752 0.4420 0.4378 0.4309 0.0 6qph:A, 6rhz:A, 6sl5:A, 6yxr:A
34 6ly5:a 742 755 0.4393 0.4340 0.4265 0.0 6l4u:A
35 6kmw:aA 721 756 0.4434 0.4508 0.4299 0.0 6kmw:bA, 6kmw:cA
36 7qco:A 728 753 0.4393 0.4423 0.4276 0.0 7qco:E, 7qco:e, 7qco:a
37 7s3d:A 749 763 0.4393 0.4299 0.4220 0.0 7s3d:G, 7s3d:a
38 7dwq:A 726 753 0.4229 0.4270 0.4117 0.0
39 7lx0:G 751 767 0.4379 0.4274 0.4185 6.30e-178 7lx0:a, 7lx0:A, 6pnj:A, 6pnj:G, 6pnj:a
40 7coy:aA 685 727 0.4120 0.4409 0.4154 6.40e-178 7coy:bA, 7coy:cA
41 8jze:b 663 735 0.4229 0.4676 0.4218 1.91e-176 8jzf:b
42 8jjr:b 659 740 0.4379 0.4871 0.4338 9.77e-175
43 8jw0:b 617 719 0.4161 0.4943 0.4242 9.62e-174
44 6kmx:aA 717 753 0.4175 0.4268 0.4064 7.54e-171 6kmx:bA, 6kmx:cA
45 8jjr:a 665 740 0.3247 0.3579 0.3216 3.91e-101
46 8jze:a 670 738 0.3042 0.3328 0.3022 1.92e-94 8jzf:a
47 8jw0:a 645 735 0.3192 0.3628 0.3184 3.85e-94
48 7zq9:B2 180 216 0.1801 0.7333 0.6111 1.24e-75
49 7zq9:B2 180 27 0.0191 0.0778 0.5185 0.11
50 5v8k:A 600 221 0.0859 0.1050 0.2851 1.63e-12
51 6m32:A 628 80 0.0396 0.0462 0.3625 1.80e-05 6m32:a
52 8gwa:A 667 80 0.0396 0.0435 0.3625 1.95e-05 8gwa:a, 7uea:A, 7uea:a, 7ueb:A, 7ueb:a, 7z6q:A, 7z6q:a
53 7vzg:a 858 116 0.0396 0.0338 0.2500 0.002 7vzg:A, 7vzr:A, 7vzr:a
54 4gfv:B 288 61 0.0286 0.0729 0.3443 1.1 4gfu:A, 4gfv:A, 4nnd:A, 4nnd:B, 4nnd:D, 4nnd:G
55 4xsc:B 284 98 0.0355 0.0915 0.2653 1.5 4xsc:A, 4xsc:C, 4xsc:D, 4xsd:A, 4xsd:B, 4xsd:C, 4xsd:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218