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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ALIVQKFGGTSVGTVERIQAVAQRIKRTVQGGNSLVVVVSAMGKSTDVLVDLAQQISPNPCRREMDMLLSTGEQVSIALL
SLALQEIDQPAISLTGAQVGIVTELEIRPDRLEHHLREGKVVVVAGFQGISEHLEITTLGRGGSDTSAVALAAALKADFC
EIYTDVPGILTTDPRLVPEAQLMAEITCDEMLELASLGAKVLHPRAVEIARNYGIPLVVRSSWSDEPGTKVVAPPVRSLV
GLEIAKAVDGVEYDADQAKVALLRVPDRPGVASKLFRDIAQQQVDIDLIIQSIHDGNSNDIAFTVVKDLLNTAEAVTSAI
APALRSYPEADQEAEIIVEKGIAKIAIAGAGMIGRPGIAAKMFKTLADVGVNIEMISTSEVKVSCVIDQRDADRAIAALS
NAFGVTLSPPKNLPAVRGVALDQDQAQIAIRHVPDRPGMAAQLFTALAEANISVDMIIQSQRCRINQGTPCRDIAFMVAE
GDSSQAEAILQPLIKDWLDAAIVVNKAIAKVSIVGSGMIGHPGVAAHFFAALAQENINIEMIATSEIKISCVVPQDRGVD
ALKAAHSAFNLAGTKTVTVPA

The query sequence (length=581) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3l76:A 585 587 0.9966 0.9897 0.9864 0.0 3l76:B
2 5yei:C 397 412 0.3391 0.4962 0.4782 1.93e-117 5yei:D, 5yei:B, 5yei:A, 5yei:F, 5yei:E, 5yei:H, 5yei:G
3 5yei:C 397 158 0.1102 0.1612 0.4051 5.68e-27 5yei:D, 5yei:B, 5yei:A, 5yei:F, 5yei:E, 5yei:H, 5yei:G
4 3aaw:C 392 407 0.3081 0.4566 0.4398 1.34e-97 3aaw:A, 3aaw:B, 3aaw:D, 3ab2:A, 3ab2:B, 3ab2:C, 3ab2:D, 3ab2:E, 3ab2:F, 3ab2:G, 3ab2:H, 3ab2:I, 3ab2:J, 3ab2:K, 3ab2:L, 3ab2:M, 3ab2:N, 3ab2:O, 3ab2:P, 3ab4:B, 3ab4:D, 3ab4:F, 3ab4:H, 3ab4:J, 3ab4:K, 3ab4:L, 3ab4:M, 3ab4:N, 3ab4:P, 2dtj:A, 2dtj:B
5 3aaw:C 392 158 0.1084 0.1607 0.3987 1.30e-27 3aaw:A, 3aaw:B, 3aaw:D, 3ab2:A, 3ab2:B, 3ab2:C, 3ab2:D, 3ab2:E, 3ab2:F, 3ab2:G, 3ab2:H, 3ab2:I, 3ab2:J, 3ab2:K, 3ab2:L, 3ab2:M, 3ab2:N, 3ab2:O, 3ab2:P, 3ab4:B, 3ab4:D, 3ab4:F, 3ab4:H, 3ab4:J, 3ab4:K, 3ab4:L, 3ab4:M, 3ab4:N, 3ab4:P, 2dtj:A, 2dtj:B
6 3ab4:A 370 404 0.2840 0.4459 0.4084 1.81e-85 3ab4:C, 3ab4:E, 3ab4:G, 3ab4:I, 3ab4:O
7 3ab4:A 370 156 0.1067 0.1676 0.3974 1.31e-26 3ab4:C, 3ab4:E, 3ab4:G, 3ab4:I, 3ab4:O
8 3c1m:C 468 374 0.2220 0.2756 0.3449 8.33e-55 3c1m:A, 3c1m:B, 3c1m:D, 3c1n:A, 3c1n:B, 3c1n:C, 3c1n:D, 3c20:A, 3c20:B, 2hmf:A, 2hmf:B, 2hmf:C, 2hmf:D
9 3c1m:C 468 147 0.0878 0.1090 0.3469 1.09e-15 3c1m:A, 3c1m:B, 3c1m:D, 3c1n:A, 3c1n:B, 3c1n:C, 3c1n:D, 3c20:A, 3c20:B, 2hmf:A, 2hmf:B, 2hmf:C, 2hmf:D
10 3c1m:C 468 142 0.0740 0.0919 0.3028 8.32e-11 3c1m:A, 3c1m:B, 3c1m:D, 3c1n:A, 3c1n:B, 3c1n:C, 3c1n:D, 3c20:A, 3c20:B, 2hmf:A, 2hmf:B, 2hmf:C, 2hmf:D
11 3c1m:C 468 78 0.0516 0.0641 0.3846 3.47e-06 3c1m:A, 3c1m:B, 3c1m:D, 3c1n:A, 3c1n:B, 3c1n:C, 3c1n:D, 3c20:A, 3c20:B, 2hmf:A, 2hmf:B, 2hmf:C, 2hmf:D
12 2re1:A 148 157 0.1239 0.4865 0.4586 2.16e-32
13 2re1:A 148 160 0.0998 0.3919 0.3625 1.85e-23
14 2dt9:A 153 160 0.1119 0.4248 0.4062 2.12e-30 2dt9:B
15 2dt9:A 153 161 0.1256 0.4771 0.4534 3.00e-30 2dt9:B
16 4go7:X 165 156 0.0998 0.3515 0.3718 2.78e-27 3s1t:A, 3s1t:B
17 4go7:X 165 162 0.1084 0.3818 0.3889 5.81e-24 3s1t:A, 3s1t:B
18 2cdq:A 470 468 0.2065 0.2553 0.2564 2.01e-25 2cdq:B
19 2cdq:A 470 53 0.0258 0.0319 0.2830 0.24 2cdq:B
20 3tvi:E 439 284 0.1343 0.1777 0.2746 2.44e-22 3tvi:A, 3tvi:B, 3tvi:C, 3tvi:D, 3tvi:G, 3tvi:H, 3tvi:I, 3tvi:L
21 3tvi:E 439 88 0.0499 0.0661 0.3295 4.28e-05 3tvi:A, 3tvi:B, 3tvi:C, 3tvi:D, 3tvi:G, 3tvi:H, 3tvi:I, 3tvi:L
22 3tvi:E 439 128 0.0551 0.0729 0.2500 1.9 3tvi:A, 3tvi:B, 3tvi:C, 3tvi:D, 3tvi:G, 3tvi:H, 3tvi:I, 3tvi:L
23 2j0w:A 447 469 0.2186 0.2841 0.2708 1.98e-20 2j0x:A, 2j0x:B
24 2j0w:A 447 163 0.0688 0.0895 0.2454 0.054 2j0x:A, 2j0x:B
25 2bmu:B 226 85 0.0516 0.1327 0.3529 9.67e-05 2bmu:A, 2bri:A, 2bri:B, 2ji5:A, 2ji5:B
26 3nwy:B 231 226 0.1015 0.2554 0.2611 4.35e-04 7bes:A, 7bes:B, 7bes:C, 7bix:A, 7bix:C, 7bix:B, 7bix:E, 7bix:D, 7bix:G, 7bix:I, 7bix:H, 7bix:K, 7bix:J, 7bl7:B, 7bl7:A, 7bl7:C, 7bl7:F, 7bl7:D, 7bl7:E, 7bl7:I, 7bl7:K, 7bl7:J, 7bl7:H, 7bl7:L, 7bl7:G, 3nwy:A, 3nwy:D, 3nwy:C, 3nwy:E, 3nwy:F
27 3ek5:A 241 169 0.0775 0.1867 0.2663 0.039 3ek5:B, 3ek5:C, 3ek5:F, 3ek5:E, 3ek5:D
28 4v8m:BM 138 107 0.0620 0.2609 0.3364 0.055
29 3lkk:B 238 45 0.0258 0.0630 0.3333 0.88 3lkk:A, 3ll5:A, 3ll5:B, 3ll5:C, 3ll5:D
30 7nf6:A 623 73 0.0310 0.0289 0.2466 0.90 7nf7:A, 7nf8:A
31 2j5t:D 365 45 0.0310 0.0493 0.4000 1.3 2j5t:A, 2j5t:B, 2j5t:C, 2j5t:E, 2j5t:F, 2j5t:G
32 7l1k:B 660 47 0.0293 0.0258 0.3617 1.7
33 2j4j:F 226 211 0.0757 0.1947 0.2085 1.9 2j4j:A, 2j4j:E, 2j4j:B, 2j4j:D, 2j4j:C, 2j4k:A, 2j4k:B, 2j4k:D, 2j4k:E, 2j4k:F, 2j4l:A, 2j4l:B, 2j4l:C, 2j4l:D, 2j4l:E, 2j4l:F, 2j4l:G, 2j4l:I, 2j4l:J, 2j4l:K, 2j4l:L
34 4a7x:C 234 111 0.0482 0.1197 0.2523 2.5 4a7w:A, 4a7w:B, 4a7x:B, 4a7x:D, 4a7x:E
35 6j31:B 387 62 0.0327 0.0491 0.3065 4.5 6j31:A, 6j31:C, 6j31:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218