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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ALIVQKFGGTSVGTVERIQAVAQRIKRTVQGGNSLVVVVSAMGKSTDVLVDLAQQISPNPCRREMDMLLSTGEQVSIALL
SLALQEIDQPAISLTGAQVGIVTEILEIRPDRLEHHLREGKVVVVAGFQGIHLEITTLGRGGSDTSAVALAAALKADFCE
IYTDVPGILTTDPRLVPEAQLMAEITCDEMLELASLGAKVLHPRAVEIARNYGIPLVVRSSWSDEPGTKVVAPPVQNRSL
VGLEIAKAVDGVEYDADQAKVALLRVPDRPGVASKLFRDIAQQQVDIDLIIQSIHDGNSNDIAFTVVKDLLNTAEAVTSA
IAPALRSYPEADQEAEIIVEKGIAKIAIAGAGMIGRPGIAAKMFKTLADVGVNIEMISTSEVKVSCVIDQRDADRAIAAL
SNAFGVTLSPPKNQTDLPAVRGVALDQDQAQIAIRHVPDRPGMAAQLFTALAEANISVDMIIQSQRCRINQGTPCRDIAF
MVAEGDSSQAEAILQPLIKDWLDAAIVVNKAIAKVSIVGSGMIGHPGVAAHFFAALAQENINIEMIATSEIKISCVVPQD
RGVDALKAAHSAFNLAGTKTVTVPA

The query sequence (length=585) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3l76:A 585 585 1.0000 1.0000 1.0000 0.0 3l76:B
2 5yei:C 397 414 0.3385 0.4987 0.4783 1.73e-116 5yei:D, 5yei:B, 5yei:A, 5yei:F, 5yei:E, 5yei:H, 5yei:G
3 5yei:C 397 158 0.1094 0.1612 0.4051 4.90e-27 5yei:D, 5yei:B, 5yei:A, 5yei:F, 5yei:E, 5yei:H, 5yei:G
4 3aaw:C 392 409 0.3060 0.4566 0.4377 1.04e-96 3aaw:A, 3aaw:B, 3aaw:D, 3ab2:A, 3ab2:B, 3ab2:C, 3ab2:D, 3ab2:E, 3ab2:F, 3ab2:G, 3ab2:H, 3ab2:I, 3ab2:J, 3ab2:K, 3ab2:L, 3ab2:M, 3ab2:N, 3ab2:O, 3ab2:P, 3ab4:B, 3ab4:D, 3ab4:F, 3ab4:H, 3ab4:J, 3ab4:K, 3ab4:L, 3ab4:M, 3ab4:N, 3ab4:P, 2dtj:A, 2dtj:B
5 3aaw:C 392 158 0.1077 0.1607 0.3987 1.60e-27 3aaw:A, 3aaw:B, 3aaw:D, 3ab2:A, 3ab2:B, 3ab2:C, 3ab2:D, 3ab2:E, 3ab2:F, 3ab2:G, 3ab2:H, 3ab2:I, 3ab2:J, 3ab2:K, 3ab2:L, 3ab2:M, 3ab2:N, 3ab2:O, 3ab2:P, 3ab4:B, 3ab4:D, 3ab4:F, 3ab4:H, 3ab4:J, 3ab4:K, 3ab4:L, 3ab4:M, 3ab4:N, 3ab4:P, 2dtj:A, 2dtj:B
6 3ab4:A 370 405 0.2821 0.4459 0.4074 3.15e-85 3ab4:C, 3ab4:E, 3ab4:G, 3ab4:I, 3ab4:O
7 3ab4:A 370 156 0.1060 0.1676 0.3974 1.54e-26 3ab4:C, 3ab4:E, 3ab4:G, 3ab4:I, 3ab4:O
8 3c1m:C 468 377 0.2256 0.2821 0.3501 9.43e-53 3c1m:A, 3c1m:B, 3c1m:D, 3c1n:A, 3c1n:B, 3c1n:C, 3c1n:D, 3c20:A, 3c20:B, 2hmf:A, 2hmf:B, 2hmf:C, 2hmf:D
9 3c1m:C 468 150 0.0872 0.1090 0.3400 5.87e-15 3c1m:A, 3c1m:B, 3c1m:D, 3c1n:A, 3c1n:B, 3c1n:C, 3c1n:D, 3c20:A, 3c20:B, 2hmf:A, 2hmf:B, 2hmf:C, 2hmf:D
10 3c1m:C 468 142 0.0735 0.0919 0.3028 8.64e-11 3c1m:A, 3c1m:B, 3c1m:D, 3c1n:A, 3c1n:B, 3c1n:C, 3c1n:D, 3c20:A, 3c20:B, 2hmf:A, 2hmf:B, 2hmf:C, 2hmf:D
11 3c1m:C 468 78 0.0513 0.0641 0.3846 3.56e-06 3c1m:A, 3c1m:B, 3c1m:D, 3c1n:A, 3c1n:B, 3c1n:C, 3c1n:D, 3c20:A, 3c20:B, 2hmf:A, 2hmf:B, 2hmf:C, 2hmf:D
12 2re1:A 148 157 0.1231 0.4865 0.4586 2.52e-32
13 2re1:A 148 160 0.0991 0.3919 0.3625 2.10e-23
14 2dt9:A 153 160 0.1111 0.4248 0.4062 1.85e-30 2dt9:B
15 2dt9:A 153 161 0.1248 0.4771 0.4534 2.67e-30 2dt9:B
16 4go7:X 165 156 0.0991 0.3515 0.3718 2.96e-27 3s1t:A, 3s1t:B
17 4go7:X 165 162 0.1077 0.3818 0.3889 5.55e-24 3s1t:A, 3s1t:B
18 2cdq:A 470 470 0.2051 0.2553 0.2553 4.61e-27 2cdq:B
19 2cdq:A 470 53 0.0256 0.0319 0.2830 0.25 2cdq:B
20 3tvi:E 439 296 0.1368 0.1822 0.2703 6.31e-21 3tvi:A, 3tvi:B, 3tvi:C, 3tvi:D, 3tvi:G, 3tvi:H, 3tvi:I, 3tvi:L
21 3tvi:E 439 88 0.0496 0.0661 0.3295 4.21e-05 3tvi:A, 3tvi:B, 3tvi:C, 3tvi:D, 3tvi:G, 3tvi:H, 3tvi:I, 3tvi:L
22 2j0w:A 447 466 0.2137 0.2796 0.2682 2.29e-19 2j0x:A, 2j0x:B
23 2j0w:A 447 166 0.0701 0.0917 0.2470 0.15 2j0x:A, 2j0x:B
24 2bmu:B 226 85 0.0513 0.1327 0.3529 8.83e-05 2bmu:A, 2bri:A, 2bri:B, 2ji5:A, 2ji5:B
25 3nwy:B 231 223 0.1009 0.2554 0.2646 2.12e-04 7bes:A, 7bes:B, 7bes:C, 7bix:A, 7bix:C, 7bix:B, 7bix:E, 7bix:D, 7bix:G, 7bix:I, 7bix:H, 7bix:K, 7bix:J, 7bl7:B, 7bl7:A, 7bl7:C, 7bl7:F, 7bl7:D, 7bl7:E, 7bl7:I, 7bl7:K, 7bl7:J, 7bl7:H, 7bl7:L, 7bl7:G, 3nwy:A, 3nwy:D, 3nwy:C, 3nwy:E, 3nwy:F
26 4v8m:BM 138 107 0.0615 0.2609 0.3364 0.033
27 3ek5:A 241 145 0.0667 0.1618 0.2690 0.091 3ek5:B, 3ek5:C, 3ek5:F, 3ek5:E, 3ek5:D
28 3dwf:B 275 87 0.0427 0.0909 0.2874 0.14 3dwf:A, 3dwf:C, 3dwf:D, 3g49:A, 3g49:B, 3g49:C, 3g49:D, 3lz6:A, 3lz6:B, 3lz6:C, 3lz6:D, 1xse:A, 1xse:B
29 7nf6:A 623 84 0.0359 0.0337 0.2500 0.36 7nf7:A, 7nf8:A
30 4a7x:C 234 104 0.0462 0.1154 0.2596 0.86 4a7w:A, 4a7w:B, 4a7x:B, 4a7x:D, 4a7x:E
31 3lkk:B 238 45 0.0256 0.0630 0.3333 0.94 3lkk:A, 3ll5:A, 3ll5:B, 3ll5:C, 3ll5:D
32 2j5t:D 365 45 0.0308 0.0493 0.4000 1.4 2j5t:A, 2j5t:B, 2j5t:C, 2j5t:E, 2j5t:F, 2j5t:G
33 7l1k:B 660 47 0.0291 0.0258 0.3617 1.6
34 3ce9:A 349 44 0.0274 0.0458 0.3636 2.4 3ce9:B, 3ce9:C, 3ce9:D
35 6je3:A 858 46 0.0274 0.0186 0.3478 6.3
36 6je4:O 1049 46 0.0274 0.0153 0.3478 7.5 8hj4:A, 8ja0:A, 6je9:C
37 6jdv:A 1036 46 0.0274 0.0154 0.3478 7.6 6kc8:A
38 6jdq:A 1069 46 0.0274 0.0150 0.3478 7.7 6je4:A, 6je4:E, 6je4:K, 6je9:A
39 8asn:G 346 65 0.0359 0.0607 0.3231 8.2 8asn:H, 8asn:I, 5m7g:F
40 6j31:B 387 64 0.0325 0.0491 0.2969 9.0 6j31:A, 6j31:C, 6j31:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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