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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ALFVHRDTPKNNPETPFDFTPENYKRIEAIVKNYPEGHKAAAVLPVLDLAQRQNGWLPISAMNKVAEILQVPPMRVYEVA
TFYTMYNRKPVGKYHIQVCTTTPCMLRNSDSILEAIQKKLGIKVGETTPDKLFTLIEVECLGACVNAPMVQINDNYYEDL
TPKDIEEIIDELKAGKIPKPGPRSGRFSCEPAGGLTSLTEPPKGPGFGVQAGL

The query sequence (length=213) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7v2c:O 217 213 0.9906 0.9724 0.9906 7.89e-159 7ak5:E, 7ak6:E, 7b93:E, 8c2s:E, 8ca3:E, 8ca4:E, 8ca5:E, 7dgq:9, 7dgr:9, 7dgs:9, 7dgz:9, 7dh0:9, 7dkf:92, 6g2j:E, 6g72:E, 5gpn:d, 8iao:E, 8iap:E, 8ib4:E, 8ib5:E, 8ib9:E, 8iba:E, 8ibd:E, 8ibe:E, 8ic2:E, 8ic3:E, 5lc5:E, 5ldw:E, 5ldx:E, 5lnk:2, 5o31:E, 8olt:E, 8om1:E, 7psa:E, 8pw5:2, 8pw6:2, 8pw7:2, 8q0a:E, 8q0f:E, 8q0j:E, 8q0m:E, 8q0o:E, 8q0q:E, 8q1p:E, 8q1u:E, 8q1y:E, 8q25:E, 8q45:E, 8q46:E, 8q47:E, 8q48:E, 8q49:E, 8q4a:E, 6q9d:V2, 6qa9:V2, 6qbx:V2, 6qc2:V2, 6qc3:V2, 6qc4:V2, 6qc5:V2, 6qc6:V2, 6qc7:V2, 6qc8:V2, 6qc9:V2, 6qca:V2, 6qcf:V2, 7qsd:E, 7qsk:E, 7qsl:E, 7qsm:E, 7qsn:E, 7qso:E, 7r41:E, 7r42:E, 7r43:E, 7r44:E, 7r45:E, 7r46:E, 7r47:E, 7r48:E, 7r4c:E, 7r4d:E, 7r4f:E, 7r4g:E, 8rgp:2, 8rgq:2, 8rgr:2, 8rgt:2, 8ud1:1E, 8ueo:1E, 8uep:1E, 8ueq:1E, 8uer:1E, 8ues:1E, 8uet:1E, 8ueu:1E, 8uev:1E, 8uew:1E, 8uex:1E, 8uey:1E, 8uez:1E, 8ugh:1E, 8ugi:1E, 8ugj:1E, 8ugn:1E, 8ugn:5E, 8ugr:1E, 8ugr:5E, 7v2d:O, 7v2e:O, 7v2f:O, 7v2h:O, 7v2k:O, 7v2r:O, 7v30:O, 7v31:O, 7v32:O, 7v33:O, 7v3m:O, 7vb7:O, 7vbn:O, 7vbz:O, 7vwj:O, 7vxp:O, 7vxu:O, 7vy8:O, 7vya:O, 7vyf:O, 7vyh:O, 7vyn:O, 7vz1:O, 7vzv:O, 7vzw:O, 7w00:O, 7w0h:O, 7w0r:O, 7w0y:O, 7w1o:O, 7w1p:O, 7w1t:O, 7w1u:O, 7w1v:O, 7w1z:O, 7w20:O, 7w2k:O, 7w2l:O, 7w2r:O, 7w2u:O, 7w2y:O, 7w31:O, 7w32:O, 7w35:O, 7w4c:O, 7w4d:O, 7w4e:O, 7w4f:O, 7w4g:O, 7w4j:O, 7w4k:O, 7w4l:O, 7w4m:O, 7w4n:O, 7w4q:O, 5xtb:O, 5xtd:O, 5xth:O, 5xti:O, 5xti:BO, 7zd6:2, 7zdh:2, 7zdj:2, 7zdm:2, 7zdp:2, 7zeb:2, 6zk9:2, 6zkc:2, 6zkd:2, 6zke:2, 6zkf:2, 6zkg:2, 6zkh:2, 6zki:2, 6zkj:2, 6zkk:2, 6zkl:2, 6zkm:2, 6zkn:2, 6zko:2, 6zkp:2, 6zkq:2, 6zkr:2, 6zks:2, 6zkt:2, 6zku:2, 6zkv:2, 6zr2:E, 6ztq:E
2 5gup:E 197 172 0.8028 0.8680 0.9942 3.57e-129
3 8b9z:E 214 212 0.7230 0.7196 0.7264 1.28e-115 8ba0:E, 8esw:V2, 8esz:V2
4 7zmb:H 221 212 0.6526 0.6290 0.6557 1.77e-98 7zm7:H, 7zmg:H
5 7b0n:E 216 212 0.5822 0.5741 0.5849 1.92e-88 6gcs:H, 7o6y:H, 7o71:H, 6rfq:H, 6rfr:H, 6rfs:H, 6y79:H, 6yj4:E
6 7arc:E 235 203 0.5070 0.4596 0.5320 2.34e-75 7ard:E
7 8e73:V2 222 217 0.5211 0.5000 0.5115 5.18e-74 6x89:V2
8 7a23:B 219 219 0.4977 0.4840 0.4840 1.63e-72 7a24:B, 7aqr:E, 7ar7:E, 7ar8:E, 7arb:E, 8bed:E, 8bpx:E, 8bq5:E, 8bq6:E
9 8iuf:V2 225 206 0.4836 0.4578 0.5000 1.71e-69 8j9h:V2, 8j9i:V2, 8j9j:V2
10 8b6f:AI 231 201 0.4695 0.4329 0.4975 4.51e-67 8bqs:AI, 8gym:v2, 8gym:V2, 8gzu:v2, 8gzu:V2, 7tgh:V2
11 8qby:E 236 189 0.3897 0.3517 0.4392 3.32e-54
12 8e9g:E 233 209 0.3756 0.3433 0.3828 1.04e-39 8e9h:E, 8e9i:E
13 3iam:2 179 159 0.2770 0.3296 0.3711 1.31e-35 2fug:2, 2fug:B, 2fug:K, 2fug:T, 4hea:2, 4hea:C, 6i0d:2, 6i0d:C, 6i1p:2, 6i1p:C, 3i9v:2, 3i9v:B, 3iam:B, 3ias:2, 3ias:B, 3ias:K, 3ias:T, 3m9s:2, 3m9s:B, 6q8o:2, 6q8o:C, 6q8w:2, 6q8w:C, 6q8x:2, 6q8x:C, 6y11:2, 6y11:C, 2ybb:2, 6ziy:2, 6zjl:2, 6zjn:2, 6zjy:2
14 8a6t:C 151 131 0.2535 0.3576 0.4122 1.15e-32 8a6t:F, 8bew:C, 8bew:F
15 7p5h:C 156 151 0.2629 0.3590 0.3709 4.16e-31 7p5h:F, 7p5h:c, 7p5h:f, 7p8n:c, 7p8n:C, 7p91:c, 7p91:C, 7p92:C
16 7t2r:C 152 137 0.2582 0.3618 0.4015 1.08e-30 7t2r:H
17 8oh5:A 150 146 0.2582 0.3667 0.3767 9.78e-30 8oh5:D, 8oh5:G, 8oh5:J, 8oh9:A, 8oh9:D, 8oh9:G, 8oh9:J
18 7awt:E 156 157 0.2582 0.3526 0.3503 1.58e-29 7nyr:E, 7nyu:E, 7nyv:E, 7nz1:E, 7p61:E, 7p62:E, 7p63:E, 7p64:E, 7p69:E, 7p7c:E, 7p7e:E, 7p7j:E, 7p7k:E, 7p7l:E, 7p7m:E, 7z7r:E, 7z7s:E, 7z7t:E, 7z7v:E, 7z80:E, 7z83:E, 7z84:E, 7zc5:E, 7zci:E
19 9fdk:C 160 156 0.2488 0.3312 0.3397 6.34e-28 9fdj:A, 9fdj:C, 9fdk:A, 9fdv:A, 9fdv:C, 9fe0:A, 9fe0:C, 9fe5:A, 9fe5:C, 9fe7:A, 9fe7:C, 9fe8:A, 9fe8:C, 9fea:A, 9fea:C, 9fif:A, 9fif:C, 9fih:A, 9fih:C, 9fii:A, 9fii:C, 9fij:A, 9fij:C, 9fil:A, 9fil:C, 6hl2:A, 6hl2:C, 6hl3:A, 6hl3:C, 6hl4:A, 6hl4:C, 6hla:A, 6hla:C, 6hli:A, 6hli:C, 6hlj:A, 6hlj:C, 6hlm:A, 6hlm:C, 7q5y:E, 7q5y:K, 7q5y:Q, 7q5y:W, 6q9c:A, 6q9c:C, 6q9g:A, 6q9g:C, 6q9j:A, 6q9j:C, 6q9k:A, 6q9k:C, 8qg1:A, 8qg1:C, 8qgw:A, 8qgw:C, 8qh4:A, 8qh4:C, 8qh7:A, 8qh7:C, 8qhk:A, 8qhk:C, 6r7p:A, 6r7p:C, 6saq:A, 6saq:C
20 8a5e:C 156 150 0.2441 0.3333 0.3467 6.28e-27 7q4v:C, 7q4v:G, 7q4w:C, 7q4w:G
21 6vw8:C 152 154 0.2113 0.2961 0.2922 1.21e-19 6vw7:A, 6vw7:C, 6vw8:A
22 2auv:A 85 82 0.1362 0.3412 0.3537 5.68e-17
23 6tg9:G 148 150 0.1878 0.2703 0.2667 1.50e-15 6tg9:C, 6tga:G, 6tga:C
24 7vw6:B 560 115 0.1315 0.0500 0.2435 9.03e-08 7e5z:B, 8j83:B, 7xqw:B
25 1f37:B 110 78 0.0986 0.1909 0.2692 0.003 1f37:A, 1m2a:A, 1m2a:B, 1m2b:A, 1m2b:B, 1m2d:A, 1m2d:B
26 5xfa:A 581 122 0.1221 0.0448 0.2131 0.007 5xf9:A, 5xf9:E, 5xfa:E
27 7p8n:B 613 88 0.1127 0.0392 0.2727 0.016 7p5h:B, 7p5h:E, 7p5h:b, 7p5h:e, 7p8n:b, 7p91:b, 7p91:B, 7p92:B
28 8hfr:zp 88 64 0.0845 0.2045 0.2812 0.019 7bt6:z, 7btb:z, 6elz:z, 6em1:z, 6em5:z, 6ft6:z, 3jct:z, 6m62:z, 6n8j:z, 6n8k:z, 6n8l:z, 7nac:z, 7oh3:z, 7ohq:z, 7r7a:z, 7u0h:z, 7uoo:z, 7uqb:z, 7uqz:z, 7v08:z, 8v87:z, 6ylx:z, 6yly:z, 7z34:z
29 6h8k:H 154 19 0.0610 0.0844 0.6842 0.17 4wz7:H
30 6nag:A 351 79 0.0986 0.0598 0.2658 0.39 5l20:B
31 3iyd:C 1089 119 0.1362 0.0266 0.2437 0.85
32 4s20:C 1179 119 0.1362 0.0246 0.2437 1.1 4s20:H
33 8sy7:I 1170 119 0.1362 0.0248 0.2437 1.2 8igr:I, 8sy5:I, 8sy6:I
34 6vyx:AA 1223 119 0.1362 0.0237 0.2437 1.2 6vyy:AA, 6vyz:AA, 6vz3:AA
35 8txo:I 1024 119 0.1362 0.0283 0.2437 1.2
36 8pil:I 1342 119 0.1362 0.0216 0.2437 1.3 8ac0:C, 7adb:X, 7adc:X, 7add:X, 7ade:X, 6b6h:C, 7bef:C, 7beg:C, 6byu:C, 7c17:C, 6c6s:I, 7c97:C, 6ca0:C, 7chw:C, 6cux:C, 7d7d:C, 7dy6:C, 8e3f:A, 8e5k:A, 8e5o:A, 8e6x:A, 8e6z:A, 8eg8:I, 8egb:I, 6flq:C, 8ftd:I, 6gfw:C, 6gh5:C, 6gov:X, 5ipl:C, 5ipm:C, 5ipn:C, 6jnx:C, 8jo2:C, 6k4y:C, 8k58:C, 8k5a:C, 7khb:C, 7khc:C, 7khe:C, 7khi:C, 6kj6:C, 4kmu:C, 4kmu:H, 4kn4:C, 4kn4:H, 4kn7:C, 4kn7:H, 6ldi:C, 7m8e:C, 4mex:C, 4mex:I, 7mkd:I, 7mke:I, 7mki:I, 7mkj:I, 7mkn:C, 6n4c:C, 7n4e:C, 6n57:I, 6n58:I, 6n60:C, 6omf:C, 6oul:I, 6p18:C, 6p19:C, 6pb4:C, 6pb5:C, 6pb6:C, 8pdy:I, 8ph9:I, 6pmi:C, 6pmj:C, 6psq:I, 6psr:I, 6pst:I, 6psu:I, 6psv:I, 6psw:I, 7py0:C, 7py1:C, 7py3:C, 7py5:C, 7py6:C, 7py7:C, 7py8:C, 7pyj:C, 7pyk:C, 7q0j:C, 7q0k:C, 8re4:C, 8rea:C, 8reb:C, 8rec:C, 8red:C, 8ree:C, 7szj:C, 7szk:C, 8to1:I, 8to6:I, 8to8:I, 8toe:I, 8tom:I, 6tqn:X, 6tqo:X, 8u3b:C, 5uac:C, 5uah:C, 5ual:C, 7ubm:C, 7ubn:C, 6utv:CCC, 6utw:CCC, 6utx:CCC, 6uty:CCC, 6utz:CCC, 6uu0:CCC, 6uu1:CCC, 6uu2:CCC, 6uu3:CCC, 6uu4:CCC, 6uu5:CCC, 6uu6:CCC, 6uu7:CCC, 6uu8:CCC, 6uu9:CCC, 6uua:CCC, 6uub:CCC, 6uuc:CCC, 6vjs:C, 5vt0:I, 6vu3:AA, 7vwy:C, 7vwz:C, 6vyq:AA, 6vyr:AA, 6vys:AA, 6vyt:AA, 6vyu:AA, 6vyw:AA, 6vz2:AA, 6vz5:AA, 6vz7:AA, 6vzj:AA, 7w5w:C, 7w5x:C, 7w5y:C, 6wmu:C, 6x6t:AA, 6x7f:AA, 6x7k:AA, 6x9q:AA, 6xas:I, 6xdq:AA, 6xdr:AA, 6xgf:AA, 6xh7:C, 6xh8:C, 6xij:AA, 6xl5:C, 6xl9:C, 6xlj:C, 6xll:C, 6xlm:C, 6xln:C, 4xsx:C, 4xsx:I, 4xsy:C, 4xsy:I, 4xsz:C, 4xsz:I, 7xue:I, 7xui:I, 8y6u:C, 4yfn:I, 4yfx:C, 4yln:C, 4yln:I, 4yln:O, 4ylo:C, 4ylo:I, 4ylo:O, 4ylp:C, 4ylp:I, 4ylp:O, 6z9p:X, 6z9q:X, 6z9r:X, 6z9s:X, 6z9t:X, 4zh2:C, 4zh2:I, 4zh3:C, 4zh3:I, 4zh4:C, 4zh4:I
37 7ypb:C 1292 119 0.1362 0.0224 0.2437 1.4 7ypa:C
38 8pen:I 1321 119 0.1362 0.0220 0.2437 1.4 8aby:C, 8abz:C, 8ac1:C, 8acp:C, 8ad1:C, 6alf:I, 6alg:I, 6alh:I, 6asx:I, 6bjs:I, 6c6t:I, 6c6u:I, 7d7c:C, 8eg7:I, 8eh8:I, 8eh9:I, 8eha:I, 8ehf:I, 8ehi:I, 8f3c:I, 8fix:C, 8fiy:C, 6flp:C, 8fvr:F, 8fvw:F, 8g00:I, 8g1s:I, 8g2w:I, 8g4w:I, 8g7e:I, 8g8z:I, 6jbq:C, 7mko:C, 8pbl:F, 8pfg:I, 8pfj:I, 8phk:I, 8pib:I, 8pid:I, 8pim:I, 6rh3:C, 6ri7:C, 6ri9:C, 6rin:C, 6rip:C, 8upo:AA, 8upr:AA, 8uql:AA, 8uqm:AA, 8uqp:AA, 8ur0:AA, 8urh:AA, 8uri:AA, 8urx:AA, 8ury:AA, 7uwe:I, 7uwh:I, 6x26:I, 6x2f:I, 6x2n:I, 6x43:I, 6x4w:I, 6x4y:I, 6x50:I, 6xav:I, 6xii:AA, 7xug:I, 6ztj:CC, 6ztl:CC, 6ztm:CC, 6ztn:CC, 6zto:CC, 6ztp:CC, 6zu1:CC
39 5ms0:C 1291 119 0.1362 0.0225 0.2437 1.5
40 1e9m:A 106 75 0.0892 0.1792 0.2533 1.5 1uwm:A
41 5ug1:A 179 26 0.0657 0.0782 0.5385 2.8
42 8a6t:B 630 88 0.1033 0.0349 0.2500 4.0 8a6t:E, 8bew:B, 8bew:E
43 4njg:A 209 97 0.1127 0.1148 0.2474 4.1 4njg:B, 4njh:A, 4njh:B, 4nji:A, 4nji:B, 4njj:A, 4njj:B, 4njk:A, 4njk:B
44 7qy5:B 320 42 0.0610 0.0406 0.3095 4.3 7qy5:D
45 5bpf:C 306 60 0.0845 0.0588 0.3000 4.7 5bpf:B, 5bpf:D, 5bph:A, 5bph:B, 5bph:C, 5bph:D, 5c1o:A, 5c1o:B, 5c1o:C, 5c1o:D, 5c1p:B, 5c1p:C, 5c1p:D
46 4zgl:F 102 73 0.0939 0.1961 0.2740 5.7 4zgl:B, 4zgl:C, 4zgl:H, 4zgl:I
47 2f4l:C 278 39 0.0563 0.0432 0.3077 6.1 2f4l:A, 2f4l:B, 2f4l:D
48 5vlq:B 413 41 0.0657 0.0339 0.3415 7.2
49 6b3x:A 327 88 0.0986 0.0642 0.2386 8.6
50 8f6y:C 409 37 0.0751 0.0391 0.4324 9.3 8f6z:C, 7smm:C, 7smq:C, 7smr:C, 7sms:C, 7smt:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218