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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ALFGYARVSTSQQSLDIQVRALKDAGVKANRIFTDKASGSSSDRKGLDLLRMKVKEGDVILVKKLDRLGRDTADMIQLIK
EFDAQGVSIRFIDDGISTDSYIGKMVVTILSAVAQAERQRILQRTNEGRQEAMAKGVVFGRKRKIDRDAVLNMWQQGLGA
SHISKTMNIARSTVYKVINESN

The query sequence (length=182) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1gdt:A 183 181 0.9670 0.9617 0.9724 1.17e-125 1gdt:B, 2gm4:A, 2gm4:B, 1zr2:A, 1zr2:B, 1zr4:A, 1zr4:B, 1zr4:E, 1zr4:D
2 5cy1:A 183 180 0.7582 0.7541 0.7667 2.78e-97 5cy1:B, 5cy2:A, 5cy2:B, 5cy2:E, 5cy2:F
3 4m6f:A 188 178 0.3571 0.3457 0.3652 2.34e-32
4 2r0q:C 193 195 0.3352 0.3161 0.3128 3.63e-20 2r0q:D, 2r0q:E, 2r0q:F
5 6yxx:EA 532 51 0.0934 0.0320 0.3333 1.5 7aoi:XL, 6yxy:EA
6 4af0:A 395 68 0.0934 0.0430 0.2500 6.4 4af0:B
7 6evj:C 748 76 0.1429 0.0348 0.3421 9.3 6evj:F, 6evk:C, 9f2r:C, 9f37:C, 6fhh:C, 6fhi:C, 5m3h:C, 6szu:C, 6szv:C, 6t0n:C, 6t0r:C, 6t0s:C, 6t0u:C, 6t0v:C, 6tw1:C, 4wsb:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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