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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ALAQVERTAEGVVLTLPEGTVKKLRLQVMGERIIRVTALPGTDFGIVPESIQVVAKPATNVPFSVDQAGEKLVLKTSQVS
AEVSLLDGTVSFRDAKGNVLLQEENRGTFSPVIHDPDPVDADSYALRQEFNRGSDEGFFGLGQHQNGQVNYAGENVELTT
YNLVISIPFLVSSRNYGLLWDNNSITRFGDPREAQPLNQSLKLYDAEGKEGGLTVRYFVGDELKLTRVEADFNHQFYKQG
NELENPFPEEVAGAYKNNTLRIELEGSIEAQATGKHQFKMYNSGYAQLSLDGEVVLDRWRMNWNPWYHNFYRELNAGDKH
KLKVSWKPDGGFFHLRHLDPLPANEQHELSLASETGKAIDYYFVAGDTKDDIISGYRQLTGKSVMLPKWAYGFWQSRERY
KSSDEIIQNLKEYRDRKIPIDNIVLDWSYWPEDAWGSHDFDKQFFPDPKALVDKVHAMNAQIMISVWPKFYPTTDNYKEL
NAKGFMFNRNLDEKNLDWIGKGYLNAFYDPFSPEATAIFWKQIRDKINVHGFDAWWLDAVEPDIHSNLTFEKRKWLMTPN
ARGNGAEIFNAYAVPHAEGVYQGELATDGDKRSFILTRSGFGGIQRTGSAIWSGDIVSRWSDMKDQIAAGIGTNLAGVTN
WTFDIGGFTPEDRFRHGKKGFVGSWTALDAEQVDEWQELNTRWYQFGAFVPLYRSHGQNPYREIFNIADEGTEVYNAMVW
YTKLRYYLMPYIYTLGGDTYHKDGTIMRGLVMDFPNDRKAWDINTQYMFGPAFLVNPVYEYKARSRDVYLPAGSDWYNFY
TGEKLAGGQTITADAPLARVPLFVKAGAIVPTGPLIQHVDEGLNSPLLITVYTGANGSFDIYEDDGRSLKYQQGEWSRIP
LSYDDVTGTLIIGDRVGSFTGMADERNIRVRFIAGPTADATNFDKAAAEAVTYTGKSVSIKRPR

The query sequence (length=944) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2xvk:A 944 944 1.0000 1.0000 1.0000 0.0 2xvl:A
2 7knc:A 919 939 0.5318 0.5462 0.5346 0.0
3 5jov:A 949 946 0.4619 0.4594 0.4609 0.0
4 5zn7:A 680 492 0.1748 0.2426 0.3354 5.09e-81 5zn7:C, 5zn7:D, 5zn7:F, 5zn7:H
5 5zn7:A 680 184 0.0636 0.0882 0.3261 6.33e-16 5zn7:C, 5zn7:D, 5zn7:F, 5zn7:H
6 6jr7:A 812 553 0.1833 0.2131 0.3128 1.53e-66 6jr7:B, 6jr7:C, 6jr7:D, 6jr8:A, 6jr8:B, 6jr8:C, 6jr8:D
7 6jr7:A 812 101 0.0328 0.0382 0.3069 0.042 6jr7:B, 6jr7:C, 6jr7:D, 6jr8:A, 6jr8:B, 6jr8:C, 6jr8:D
8 4ba0:A 781 577 0.1663 0.2010 0.2721 3.23e-53 4b9y:A, 4b9z:A, 5i23:A, 5i24:A, 5npb:A, 5npc:A, 5npd:A, 5npe:A, 7p4c:AAA, 7p4d:AAA, 8rw3:C, 8rw3:A, 8rw3:B
9 5x7o:A 1247 593 0.1748 0.1323 0.2782 2.15e-47 5x7o:B, 5x7p:B, 5x7p:A, 5x7q:A, 5x7q:B, 5x7r:A, 5x7r:B, 5x7s:A, 5x7s:B
10 6dru:A 718 507 0.1536 0.2019 0.2860 2.81e-44 6dru:B
11 6dru:A 718 53 0.0148 0.0195 0.2642 0.027 6dru:B
12 5hxm:A 1060 606 0.1674 0.1491 0.2607 3.88e-44 5f7u:A, 5hpo:A, 5i0d:A, 5i0d:B, 4kmq:A, 4kwu:A
13 5hxm:A 1060 136 0.0350 0.0311 0.2426 0.003 5f7u:A, 5hpo:A, 5i0d:A, 5i0d:B, 4kmq:A, 4kwu:A
14 5ief:A 858 552 0.1494 0.1643 0.2554 2.14e-40 5h9o:A, 5h9o:C, 5hjo:A, 5hjo:C, 5hjr:A, 5hjr:C, 5ied:A, 5iee:A, 5ieg:A, 7jty:A, 7jty:C, 7k9n:A, 7k9n:C, 7k9o:A, 7k9o:C, 7k9q:A, 7k9q:C, 7k9t:A, 7k9t:C, 7kad:A, 7kad:C, 7kb6:A, 7kb6:C, 7kb8:A, 7kb8:C, 7kbj:A, 7kbj:C, 7kbr:A, 7kbr:C, 7kry:A, 7kry:C
15 3l4u:A 864 518 0.1430 0.1562 0.2606 2.93e-36 3ctt:A, 3l4t:A, 3l4v:A, 3l4w:A, 3l4x:A, 3l4y:A, 3l4z:A, 2qmj:A
16 6c9x:A 666 576 0.1515 0.2147 0.2483 7.86e-36 6c9x:B, 6c9z:A, 6c9z:B, 6ca1:A, 6ca1:B, 6ca3:A, 6ca3:B, 3mkk:B, 3mkk:A, 3pha:A, 3pha:B, 3pha:C, 3pha:D, 3poc:B, 3poc:A
17 3wem:A 830 681 0.1737 0.1976 0.2408 5.78e-35 3w37:A, 3wel:A, 3wen:A, 3weo:A
18 2f2h:A 773 491 0.1229 0.1501 0.2363 1.12e-34 2f2h:B, 2f2h:C, 2f2h:D, 2f2h:E, 2f2h:F, 1xsk:A, 1xsk:B, 1xsk:C, 1xsk:E
19 7wj9:A 733 536 0.1377 0.1774 0.2425 2.85e-34 7wj9:B, 7wj9:C, 7wj9:D, 7wj9:F, 7wj9:E, 7wjb:A, 7wjc:A, 7wjd:A, 7wje:A, 7wjf:A
20 5dky:A 928 564 0.1600 0.1627 0.2677 6.09e-34 5dkz:A, 5dl0:A
21 3top:A 890 544 0.1525 0.1618 0.2647 1.44e-32 3top:B
22 5kzw:A 850 570 0.1504 0.1671 0.2491 2.54e-32 8cb1:A, 8cb6:A, 5kzx:A, 5nn4:A, 5nn5:A, 5nn6:A, 5nn8:A, 7p2z:AaA, 7p32:AAA
23 6m77:A 907 642 0.1790 0.1863 0.2632 6.21e-32 7f7q:A, 7f7r:A
24 3lpp:B 869 557 0.1462 0.1588 0.2478 8.88e-32 3lpp:D
25 5x3j:A 718 534 0.1441 0.1894 0.2547 1.31e-30 5x3j:B, 5x3k:A, 5x3k:B
26 5i0g:B 730 501 0.1250 0.1616 0.2355 1.92e-29 5f7s:A, 5f7s:B, 5i0e:B, 5i0f:B
27 4xpq:A 670 561 0.1451 0.2045 0.2442 1.38e-26 4xpp:A, 4xps:A
28 8r56:D 673 477 0.1186 0.1664 0.2348 4.81e-24 8r56:A, 8r56:B, 8r56:C
29 6pnr:A 667 478 0.1261 0.1784 0.2490 1.56e-20 6pnr:C
30 7ofx:B 665 262 0.0731 0.1038 0.2634 6.57e-20 7ofx:A, 7ofx:C, 7ofx:D, 5ohs:A, 5ohs:B, 5ohs:C, 5ohs:D, 5ohs:E, 5ohs:F, 5ohs:G, 5ohs:H, 5ohy:A, 5ohy:B, 5ohy:C, 5ohy:D
31 5aed:A 674 497 0.1239 0.1736 0.2354 8.90e-19 5aed:B, 5aee:A, 5aee:B, 5aeg:A, 5aeg:B, 5oht:A, 5oht:B
32 4amw:A 1025 321 0.0837 0.0771 0.2461 2.10e-12 4amw:B, 4amw:C, 4amw:D, 4amx:A, 4amx:B, 4amx:C, 4amx:D, 2x2i:A, 2x2i:B, 2x2i:C, 2x2i:D, 2x2j:A, 2x2j:B, 2x2j:C, 2x2j:D
33 7xoi:A 465 198 0.0572 0.1161 0.2727 4.85e-12 7xoi:C, 7xoi:E, 7xoi:G, 7xoi:I, 7xoi:K, 7xoi:M, 7xoi:O
34 7xoi:B 436 316 0.0837 0.1812 0.2500 4.99e-10 7xoi:D, 7xoi:F, 7xoi:H, 7xoi:J, 7xoi:L, 7xoi:N, 7xoi:P
35 8j51:A 510 502 0.1102 0.2039 0.2072 2.19e-09 8j51:B, 8j52:A, 8j52:B
36 7qqg:B 623 144 0.0456 0.0690 0.2986 2.01e-08 7qqg:A, 7qqg:C, 7qqh:A, 7qqh:B, 7qqh:C, 7qqh:D
37 7qqg:D 496 144 0.0456 0.0867 0.2986 3.51e-07
38 4ljr:B 213 84 0.0286 0.1268 0.3214 0.13 4ljr:A
39 3v76:A 390 115 0.0371 0.0897 0.3043 0.50
40 6qe7:A 291 174 0.0403 0.1306 0.2184 1.8 6qe7:B, 6qe7:C
41 3chv:A 279 65 0.0233 0.0789 0.3385 1.9
42 3bdz:A 397 60 0.0233 0.0554 0.3667 2.2 3bdz:B, 3be0:A, 3be0:B, 4fb2:A, 4fb2:B, 4fb2:C, 4fb2:D, 4fmx:A, 4fmx:B, 4fyz:A, 4fyz:B, 4l6g:A, 4l6g:B, 4l77:A, 4l77:B, 4lht:A, 4lht:B, 1t2b:A, 1t2b:B
43 6q45:A 476 109 0.0275 0.0546 0.2385 3.2 6q45:B, 6q45:C, 6q45:I, 6q45:J, 6q45:K
44 2xmr:A 281 54 0.0159 0.0534 0.2778 6.7
45 8dx0:B 139 79 0.0286 0.1942 0.3418 7.7
46 4h3d:B 254 50 0.0138 0.0512 0.2600 8.8 4h3d:A, 4h3d:C, 4h3d:D, 3js3:A, 3js3:B, 3js3:C, 3js3:D
47 3abi:A 349 123 0.0307 0.0831 0.2358 8.9 3abi:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218