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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AKYTKEDIFRFADEQNVKFIRLQFTDILGIIKNVEIPVSQLKKALDNKIMFDGSSIEGFVRIEESDMYLFPDLDTWVVFP
WTAEKGKVARMICDIYNPDMTPFAGDPRANLKRVLKEMEELGFTEFNLGPEPEFFLFKLDENRRPTLELNDSGGYFDLAP
TDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYEDAITACDSIQTFKLVVKTIARKHGLHATFMPKPLFGVNG
SGMHFNMSLFNEKGNAFFDESGELELSQTAYHFLAGMLKHARGYTAVTNPTINSFKRLVPGYEAPCYIAWSGKNRSPLVR
VPSSRGLSTRLELRSVDPSANPYLAMAVLLKAGLSGIKDELTPPAPVDRNIYGMNEEEREATGIYDLPESLGHALIELEK
NEIIKDGLGEHIFEHFIEAKTIECDMFRTAVHPWEREQYLEIY

The query sequence (length=443) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7tf9:S 443 443 1.0000 1.0000 1.0000 0.0 7ten:A, 7ten:E, 7ten:B, 7ten:D, 7ten:H, 7ten:J, 7ten:M, 7ten:O, 7ten:Q, 7ten:S, 7ten:U, 7ten:W, 7tf9:H, 7tf9:A, 7tf9:Q, 7tf9:C, 7tf9:O, 7tf9:B, 7tf9:P, 7tf9:R, 7tf9:I, 7tf9:T, 7tf9:F, 7tf9:G, 7tf9:N, 7tfe:A, 7tfe:G, 7tfe:H, 7tfe:I, 7tfe:B, 7tfe:C, 7tfe:J, 7tfe:D, 7tfe:E, 7tfe:F, 7tfe:K, 7tfe:L
2 4s0r:D 447 443 0.7765 0.7696 0.7765 0.0 4lnf:A, 4lnf:B, 4lnf:C, 4lnf:D, 4lnf:E, 4lnf:F, 4lnf:G, 4lnf:H, 4lnf:I, 4lnf:J, 4lnf:K, 4lnf:L, 4lni:A, 4lni:B, 4lni:C, 4lni:D, 4lni:E, 4lni:F, 4lni:G, 4lni:H, 4lni:I, 4lni:J, 4lni:K, 4lni:L, 4lnk:A, 4lnk:B, 4lnk:C, 4lnk:D, 4lnk:E, 4lnk:F, 4lnn:A, 4lnn:B, 4lnn:C, 4lnn:D, 4lnn:E, 4lnn:F, 4lnn:G, 4lnn:H, 4lnn:I, 4lnn:J, 4lnn:K, 4lnn:L, 4lno:A, 4lno:B, 4lno:C, 4lno:D, 4lno:E, 4lno:F, 4s0r:A, 4s0r:C, 4s0r:F, 4s0r:G, 4s0r:I, 4s0r:E, 4s0r:L, 4s0r:M, 4s0r:J, 4s0r:K, 4s0r:N, 4s0r:B, 4s0r:H, 7tfc:B, 7tfc:C, 7tfc:Q, 7tfc:R, 7tfc:F, 7tfc:G, 7tfc:H, 7tfc:P, 7tfc:O, 7tfc:S, 7tfc:I, 7tfc:N, 7tfc:T, 7tfc:A
3 7tdv:C 443 441 0.7540 0.7540 0.7574 0.0 7tdv:A, 7tdv:D, 7tdv:E, 7tdv:B, 7tdv:H, 7tf6:C, 7tf6:O, 7tf6:R, 7tf6:F, 7tf6:N, 7tf6:H, 7tf6:L, 7tf6:T, 7tf6:A, 7tf6:S, 7tf6:G, 7tf6:B
4 7tfa:B 441 441 0.7246 0.7279 0.7279 0.0 7tdp:A, 7tdp:C, 7tdp:B, 7tfa:L, 7tfa:Q, 7tfa:E, 7tfa:F, 7tfa:J, 7tfa:K, 7tfa:W, 7tfa:R, 7tfa:S, 7tfa:T, 7tfa:X, 7tfb:B, 7tfb:S, 7tfb:D, 7tfb:U, 7tfb:F, 7tfb:Y, 7tfb:J, 7tfb:K, 7tfb:Z, 7tfb:L, 7tfb:b, 7tfb:N, 7tfb:V, 7tfb:T, 7tfd:B, 7tfd:E, 7tfd:F, 7tfd:J, 7tfd:K, 7tfd:L, 7tfd:Q, 7tfd:R, 7tfd:S, 7tfd:T, 7tfd:W, 7tfd:X
5 8ufj:B 444 439 0.5530 0.5518 0.5581 0.0 8tfb:A, 8tfb:B, 8tfb:C, 8tfb:D, 8tfb:L, 8tfb:M, 8tfb:O, 8tfb:P, 8tfb:Q, 8tfb:V, 8tfb:X, 8tfb:Y, 8tfk:A, 8tfk:B, 8tfk:C, 8tfk:D, 8tfk:E, 8tfk:F, 8tfk:G, 8tfk:H, 8tfk:I, 8tfk:J, 8tfk:K, 8tfk:L, 8ufj:A, 8ufj:C
6 8oox:B 438 441 0.5688 0.5753 0.5714 1.02e-178 8oow:A, 8oow:B, 8oow:C, 8oow:D, 8oow:E, 8oow:F, 8oow:G, 8oow:H, 8oow:I, 8oow:J, 8oow:K, 8oow:L, 8oox:A, 8ooz:A, 8ooz:B, 8ooz:C, 8ooz:D, 8ooz:E, 8ooz:F, 8ooz:K, 8ooz:G, 8ooz:H, 8ooz:I, 8ooz:J, 8ooz:L
7 8ooo:A 447 446 0.5327 0.5280 0.5291 4.36e-173 8ooo:L, 8ooo:B, 8ooo:H, 8ooo:C, 8ooo:J, 8ooo:D, 8ooo:F, 8ooo:E, 8ooo:G, 8ooo:I, 8ooo:K, 8ooq:A, 8ooq:L, 8ooq:B, 8ooq:H, 8ooq:C, 8ooq:J, 8ooq:D, 8ooq:F, 8ooq:E, 8ooq:G, 8ooq:I, 8ooq:K, 8ooq:P, 8ooq:c, 8ooq:Q, 8ooq:Y, 8ooq:S, 8ooq:a, 8ooq:T, 8ooq:V, 8ooq:U, 8ooq:X, 8ooq:Z, 8ooq:b
8 1f1h:A 468 477 0.4086 0.3868 0.3795 3.93e-93 1f1h:B, 1f1h:C, 1f1h:D, 1f1h:E, 1f1h:F, 1f1h:G, 1f1h:H, 1f1h:I, 1f1h:J, 1f1h:K, 1f1h:L, 1f52:A, 1f52:B, 1f52:C, 1f52:D, 1f52:E, 1f52:F, 1f52:G, 1f52:H, 1f52:I, 1f52:J, 1f52:K, 1f52:L, 1fpy:A, 1fpy:B, 1fpy:C, 1fpy:D, 1fpy:E, 1fpy:F, 1fpy:G, 1fpy:H, 1fpy:I, 1fpy:J, 1fpy:K, 1fpy:L, 2gls:A, 2gls:B, 2gls:C, 2gls:D, 2gls:E, 2gls:F, 2gls:G, 2gls:H, 2gls:I, 2gls:J, 2gls:K, 2gls:L
9 1hto:A 477 478 0.3837 0.3564 0.3556 1.01e-88 4acf:A, 4acf:B, 4acf:C, 4acf:D, 4acf:E, 4acf:F, 2bvc:A, 2bvc:B, 2bvc:C, 2bvc:D, 2bvc:E, 2bvc:F, 1hto:B, 1hto:C, 1hto:D, 1hto:E, 1hto:F, 1hto:G, 1hto:H, 1hto:I, 1hto:J, 1hto:K, 1hto:L, 1hto:M, 1hto:N, 1hto:O, 1hto:P, 1hto:Q, 1hto:R, 1hto:S, 1hto:T, 1hto:U, 1hto:V, 1hto:W, 1hto:X, 1htq:A, 1htq:B, 1htq:C, 1htq:D, 1htq:E, 1htq:F, 1htq:G, 1htq:H, 1htq:I, 1htq:J, 1htq:K, 1htq:L, 1htq:M, 1htq:N, 1htq:O, 1htq:P, 1htq:Q, 1htq:R, 1htq:S, 1htq:T, 1htq:U, 1htq:V, 1htq:W, 1htq:X, 2wgs:A, 2wgs:B, 2wgs:C, 2wgs:D, 2wgs:E, 2wgs:F, 2wgs:G, 2wgs:H, 2wgs:I, 2wgs:J, 2wgs:K, 2wgs:L, 2whi:A, 2whi:B, 2whi:C, 2whi:D, 2whi:E, 2whi:F, 4xyc:A, 4xyc:B, 4xyc:C, 4xyc:D, 4xyc:E, 4xyc:F, 4xyc:G, 4xyc:H, 4xyc:I, 4xyc:J, 4xyc:K, 4xyc:L, 4xyc:M, 4xyc:N, 4xyc:O, 4xyc:P, 4xyc:Q, 4xyc:R, 4xyc:S, 4xyc:T, 4xyc:U, 4xyc:V, 4xyc:W, 4xyc:X, 3zxr:A, 3zxr:B, 3zxr:C, 3zxr:D, 3zxr:E, 3zxr:F, 3zxv:A, 3zxv:B, 3zxv:C, 3zxv:D, 3zxv:E, 3zxv:F
10 5zlp:J 478 465 0.3792 0.3515 0.3613 3.28e-83 5zlp:A, 5zlp:B, 5zlp:C, 5zlp:D, 5zlp:E, 5zlp:F, 5zlp:H, 5zlp:K, 5zlp:L, 5zlp:G, 5zlp:I
11 3ng0:A 465 474 0.3815 0.3634 0.3565 2.84e-81
12 1lgr:A 445 477 0.3815 0.3798 0.3543 9.75e-79 1lgr:B, 1lgr:C, 1lgr:D, 1lgr:E, 1lgr:F, 1lgr:G, 1lgr:H, 1lgr:I, 1lgr:J, 1lgr:K, 1lgr:L, 2lgs:A, 2lgs:B, 2lgs:C, 2lgs:D, 2lgs:E, 2lgs:F, 2lgs:G, 2lgs:H, 2lgs:I, 2lgs:J, 2lgs:K, 2lgs:L
13 4s17:A 452 475 0.3612 0.3540 0.3368 4.10e-76 4s17:B, 4s17:C, 4s17:D, 4s17:E, 4s17:F
14 7cqw:A 430 450 0.3273 0.3372 0.3222 9.68e-61 7cqn:A, 7cqn:B, 7cqn:C, 7cqq:A, 7cqq:B, 7cqq:C, 7cqu:A, 7cqu:B, 7cqu:C, 7cqw:B, 7cqw:C, 7cqx:A, 7cqx:B, 7cqx:C
15 5dm3:C 396 370 0.2641 0.2955 0.3162 1.76e-41 5dm3:D, 5dm3:B, 5dm3:E, 5dm3:F
16 8wwu:B 492 479 0.2935 0.2642 0.2714 3.68e-41 8wwu:A, 8wwu:C, 8wwu:D, 8wwu:E, 8wwu:F, 8wwv:A, 8wwv:B, 8wwv:C, 8wwv:D, 8wwv:E, 8wwv:F, 8x6z:A, 8x6z:B, 8x6z:C, 8x6z:D, 8x6z:E, 8x6z:F
17 5dm3:A 374 375 0.2528 0.2995 0.2987 1.41e-38
18 4hpp:A 426 431 0.2528 0.2629 0.2599 1.19e-28
19 3o6x:A 638 133 0.1061 0.0737 0.3534 4.20e-12 3o6x:B, 3o6x:C, 3o6x:D, 3o6x:E, 3o6x:F
20 8ecy:A 371 333 0.1986 0.2372 0.2643 6.22e-10 8dnu:A, 8ecy:J, 8ecy:L, 8ecy:Q, 8ecy:H, 8ecy:D, 8ecy:B, 8ecy:F, 8ecy:I, 8ecy:M, 2ojw:A, 2ojw:B, 2ojw:C, 2ojw:D, 2ojw:E, 2qc8:A, 2qc8:B, 2qc8:C, 2qc8:D, 2qc8:E, 2qc8:F, 2qc8:G, 2qc8:H, 2qc8:I, 2qc8:J, 2uu7:A, 2uu7:B, 2uu7:C, 2uu7:D, 2uu7:E, 2uu7:F, 2uu7:G, 2uu7:H, 2uu7:I, 2uu7:J, 2uu7:K, 2uu7:L, 2uu7:M, 2uu7:N, 2uu7:O
21 2d3a:A 353 208 0.1264 0.1586 0.2692 4.21e-09 2d3a:B, 2d3a:C, 2d3a:D, 2d3a:E, 2d3a:F, 2d3a:G, 2d3a:H, 2d3a:I, 2d3a:J, 2d3b:A, 2d3b:B, 2d3b:C, 2d3b:D, 2d3b:E, 2d3b:G, 2d3b:F, 2d3b:I, 2d3b:J, 2d3b:H, 2d3c:A, 2d3c:B, 2d3c:C, 2d3c:D, 2d3c:E, 2d3c:F, 2d3c:G, 2d3c:H, 2d3c:I, 2d3c:J
22 7u5n:A 343 241 0.1467 0.1895 0.2697 2.16e-06 7u5n:B, 7u5n:C, 7u5n:D, 7u5n:E, 7u5n:F, 7u5n:G, 7u5n:H, 7u5n:I, 7u5n:J
23 6dxs:A 342 75 0.0519 0.0673 0.3067 5.3 6dwv:B, 6dwv:A, 6dwv:C, 6dwv:D, 6dxq:A, 6dxq:B, 6dxq:C, 6dxq:D, 6dxs:B, 6dxs:C, 6dxs:D
24 6kut:A 688 54 0.0429 0.0276 0.3519 7.1 6kuj:A, 6kuk:A, 6kup:A, 6kur:A, 6kuu:A, 6kuv:A
25 3lv4:A 441 43 0.0361 0.0363 0.3721 8.7 3lv4:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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